Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 01 Mar 2024

Evaluation of binding mechanism of dietary phytochemical, capsaicin, with human transferrin: targeting neurodegenerative diseases therapeutics

in Translational Pharmacology

Mohammed Alrouji
Fahad A. Alhumaydhi
Kumar Venkatesan
Sharaf E. Sharaf
Moyad Shahwan
Anas Shamsi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1348128

2,975 views
4 citations

Original Research

Published on 23 Feb 2024

Quantification of stimulus-evoked tactile allodynia in free moving mice by the chainmail sensitivity test

in Translational Pharmacology

Yildirim Ozdemir
Kazuo Nakamoto
Bruno Boivin
Daniel Bullock
Nick A. Andrews
Rafael González-Cano
Michael Costigan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352464

3,776 views
2 citations

Perspective

Published on 22 Feb 2024

Exploiting the damaging effects of ROS for therapeutic use by deactivating cell-free chromatin: the alchemy of resveratrol and copper

in Translational Pharmacology

Indraneel Mittra

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1345786

4,413 views
9 citations

Review

Published on 13 Feb 2024

Exploring the efficacy and safety of Ambroxol in Gaucher disease: an overview of clinical studies

in Translational Pharmacology

Feda E. Mohamed
Fatma Al-Jasmi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1335058

12,190 views
11 citations

Review

Published on 08 Feb 2024

A comprehensive review of the literature on CD10: its function, clinical application, and prospects

in Translational Pharmacology

Shudong Wang
Yinghui Xiao
Xingna An
Ling Luo
Kejian Gong
Dehai Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1336310

12,539 views
17 citations

Review

Published on 08 Feb 2024

Update on the advances and challenges in bioequivalence testing methods for complex topical generic products

in Translational Pharmacology

Nedaa Alomari
Waleed Alhussaini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1330712

6,602 views
8 citations

Original Research

Published on 07 Feb 2024

Prediction of drug–disease associations based on reinforcement symmetric metric learning and graph convolution network

in Translational Pharmacology

Huimin Luo
Chunli Zhu
Jianlin Wang
Ge Zhang
Junwei Luo
Chaokun Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1337764

3,487 views
8 citations

Clinical Trial

Published on 07 Feb 2024

Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

in Translational Pharmacology

Joan Perelló
Joan Alberti
Juan Vicente Torres
Miguel D. Ferrer
M. Mar Perez
Firas Bassissi
Alex Gold
Paolo Raggi
Glenn M. Chertow
Carolina Salcedo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1325186

2,551 views
1 citation

Original Research

Published on 06 Feb 2024

Prevalence and clinical significance of potential drug-drug interactions among lung transplant patients

in Translational Pharmacology

Jiali Zhang
Danyi Ma
Meng Chen
Yanting Hu
Xveying Chen
Jingyu Chen
Man Huang
Haibin Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1308260

3,432 views
6 citations

Original Research

Published on 26 Jan 2024

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

in Translational Pharmacology

Adele Moatti
Shannon Connard
Novietta De Britto
William A. Dunn
Srishti Rastogi
Mani Rai
Lauren V. Schnabel
Frances S. Ligler
Kendall A. Hutson
Douglas C. Fitzpatrick

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1348172

5,665 views
9 citations

Clinical Trial

Published on 25 Jan 2024

Effect of dexmedetomidine on postoperative nausea and vomiting in female patients undergoing radical thoracoscopic lung cancer resection

in Translational Pharmacology

Haipeng Zhu
Shichao Wang
Ruohan Wang
Bing Li
Jiaqiang Zhang
Wei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353620

2,902 views
10 citations

Clinical Trial

Published on 19 Jan 2024

Towards a better detection of patients at-risk of linezolid toxicity in clinical practice: a prospective study in three Belgian hospital centers

in Translational Pharmacology

Hélène Thirot
David Fage
Antonia Leonhardt
Philippe Clevenbergh
Tatiana Besse-Hammer
Jean Cyr Yombi
Olivier Cornu
Caroline Briquet
Maya Hites
Frédérique Jacobs

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1310309

5,254 views
14 citations

Review

Published on 11 Jan 2024

The potential influence of melatonin on mitochondrial quality control: a review

in Translational Pharmacology

Xudan Lei
Zhenni Xu
Lingxiao Huang
Yujun Huang
Siyu Tu
Lu Xu
Dengqun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1332567

11,506 views
21 citations

Original Research

Published on 10 Jan 2024

Population pharmacokinetic modeling of ilaprazole in healthy subjects and patients with duodenal ulcer in China

in Translational Pharmacology

Mengyang Yu
Shupeng Liu
Xiaofei Wu
Hongyun Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1306222

3,468 views
1 citation

Editorial

Published on 11 Dec 2023

Editorial: Disease-on-a-chip: from point-of-care to personalized medicine

in Translational Pharmacology

Andrea Cruz
Elisabete Fernandes
Raquel O. Rodrigues
Susana O. Catarino
Diana Pinho

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1344379

2,166 views
1 citation

Clinical Trial

Published on 11 Dec 2023

A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects

in Translational Pharmacology

Qian Chen
Qingqing Wu
Rong Song
Yating Wang
Mengqi Zhang
Fangqiong Li
Weifang Zeng
Wei Wang
Jingying Jia
Chen Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1296672

4,054 views
6 citations

Original Research

Published on 07 Dec 2023

A synthetic notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay

in Translational Pharmacology

YangHao Fu
TianDuo Wang
John A. Ronald

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304194

7,840 views
6 citations

Original Research

Published on 06 Dec 2023

Quantitative systems pharmacology model of erythropoiesis to simulate therapies targeting anemia due to chronic kidney disease

in Translational Pharmacology

Mrittika Roy
Shaifali Saroha
Uddipan Sarma
Harini Sarathy
Rukmini Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1274490

4,386 views
1 citation

Original Research

Published on 30 Nov 2023

Harnessing the translational power of bleomycin model: new insights to guide drug discovery for idiopathic pulmonary fibrosis

in Translational Pharmacology

Annalisa Murgo
Fabio Bignami
Giuseppina Federico
Gino Villetti
Maurizio Civelli
Angelo Sala
Daniela Miglietta

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1303646

5,967 views
3 citations

Review

Published on 27 Nov 2023

Verapamil chronicles: advances from cardiovascular to pancreatic β-cell protection

in Translational Pharmacology

Hossein Arefanian
Lubaina Koti
Sardar Sindhu
Rasheed Ahmad
Ashraf Al Madhoun
Fahd Al-Mulla

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1322148

5,787 views
11 citations

Original Research

Published on 24 Nov 2023

Population pharmacokinetics of everolimus in patients with seizures associated with focal cortical dysplasia

in Translational Pharmacology

Jinha Park
Se Hee Kim
Jongsung Hahn
Hoon-Chul Kang
Sang-Guk Lee
Heung Dong Kim
Min Jung Chang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1197549

3,485 views
4 citations

Clinical Trial

Published on 21 Nov 2023

Effect of Berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi-centric, open-label clinical trial

in Translational Pharmacology

Francesco Di Pierro
Ruqqia Sultana
Amna Zia Eusaph
Saida Abrar
Mahroo Bugti
Fauzia Afridi
Umer Farooq
Somia Iqtadar
Fareeha Ghauri
Syeda Makhduma

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1269605

37,584 views
14 citations

Original Research

Published on 14 Nov 2023

Intraoperative parameters and postoperative follow-up of foam-based intraperitoneal chemotherapy (FBIC)

in Translational Pharmacology

Carolina Khosrawipour
Jakub Nicpoń
Zdzisław Kiełbowicz
Przemysław Prządka
Bartłomiej Liszka
Said Al-Jundi
Veria Khosrawipour
Shiri Li
Hien Lau
Joanna Kulas

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1276759

2,482 views
2 citations

Case Report

Published on 10 Nov 2023

Case report: Supratherapeutic tacrolimus concentrations with nirmatrelvir/ritonavir in a lung transplant patient: a case report using Rifampin for reversal

in Translational Pharmacology

Yu Xiong
Xiaoxing Wang
Shu Li
Qian Zhang
Lijuan Guo
Wenhui Chen
Zhixia Zhao
Lihong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1285078

3,525 views
5 citations

1,097 articles

articles

Evaluation of binding mechanism of dietary phytochemical, capsaicin, with human transferrin: targeting neurodegenerative diseases therapeutics

Quantification of stimulus-evoked tactile allodynia in free moving mice by the chainmail sensitivity test

Exploiting the damaging effects of ROS for therapeutic use by deactivating cell-free chromatin: the alchemy of resveratrol and copper

Exploring the efficacy and safety of Ambroxol in Gaucher disease: an overview of clinical studies

A comprehensive review of the literature on CD10: its function, clinical application, and prospects

Update on the advances and challenges in bioequivalence testing methods for complex topical generic products

Prediction of drug–disease associations based on reinforcement symmetric metric learning and graph convolution network

Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

Prevalence and clinical significance of potential drug-drug interactions among lung transplant patients

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

Effect of dexmedetomidine on postoperative nausea and vomiting in female patients undergoing radical thoracoscopic lung cancer resection

Towards a better detection of patients at-risk of linezolid toxicity in clinical practice: a prospective study in three Belgian hospital centers

The potential influence of melatonin on mitochondrial quality control: a review

Population pharmacokinetic modeling of ilaprazole in healthy subjects and patients with duodenal ulcer in China

Editorial: Disease-on-a-chip: from point-of-care to personalized medicine

A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects

A synthetic notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay

Quantitative systems pharmacology model of erythropoiesis to simulate therapies targeting anemia due to chronic kidney disease

Harnessing the translational power of bleomycin model: new insights to guide drug discovery for idiopathic pulmonary fibrosis

Verapamil chronicles: advances from cardiovascular to pancreatic β-cell protection

Population pharmacokinetics of everolimus in patients with seizures associated with focal cortical dysplasia

Effect of Berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi-centric, open-label clinical trial

Intraoperative parameters and postoperative follow-up of foam-based intraperitoneal chemotherapy (FBIC)

Case report: Supratherapeutic tacrolimus concentrations with nirmatrelvir/ritonavir in a lung transplant patient: a case report using Rifampin for reversal