Original Research

Published on 04 Sep 2024

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection (ALND)

in Translational Pharmacology

Stav Brown
Audree B. Tadros
Giacomo Montagna
Tajah Bell
Fionnuala Crowley
Emily J. Gallagher
Joseph H. Dayan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1457363

2,285 views

Original Research

Published on 02 Sep 2024

Unveiling novel serum biomarkers in intrahepatic cholangiocarcinoma: a pilot proteomic exploration

in Translational Pharmacology

Lavinia Patricia Mocan
Cristiana Grapa
Rareș Crăciun
Ioana Ecaterina Pralea
Alina Uifălean
Andreea Maria Soporan
Ximena Maria Mureșan
Maria Iacobescu
Nadim Al Hajjar
Carmen Mihaela Mihu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440985

1,095 views

Original Research

Published on 30 Aug 2024

The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine

in Translational Pharmacology

Jennifer McDonough
Naveen K. Singhal
Paulina M. Getsy
Katherine Knies
Zackery T. Knauss
Devin Mueller
James N. Bates
Derek S. Damron
Stephen J. Lewis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1416701

800 views

Review

Published on 28 Aug 2024

Advances in research on potential therapeutic approaches for Niemann-Pick C1 disease

in Translational Pharmacology

Caifeng Zhang
Keke Su
Xu Jiang
Yuping Tian
Ke Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465872

1,026 views

Clinical Trial

Published on 22 Aug 2024

Pharmacokinetics and safety profiles of beinaglutide injection, a recombinant human GLP-1, in adults with overweight/obesity: results from a phase I clinical trial

in Translational Pharmacology

Pingping Lin
Chengqian Li
Yanping Liu
Feifei Sun
Tsung-Han Hsieh
Lin Zhang
Yaping Ma
Xiaomeng Gao
Qing Yu
Yu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433587

1,034 views

Original Research

Published on 20 Aug 2024

In vitro evidence of antioxidant and anti-inflammatory effects of a new nutraceutical formulation explains benefits in a clinical setting of COPD patients

in Translational Pharmacology

Valentina Lazzara
Paola Pinto
Serena Di Vincenzo
Maria Ferraro
Filippo Catalano
Pietro Provinzano
Elisabetta Pace
Maria Rosaria Bonsignore

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439835

810 views

Original Research

Published on 16 Aug 2024

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius

in Translational Pharmacology

Christian E. Edvardsson
Jesper Vestlund
Mia Ericson
Elisabet Jerlhag

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439203

1,049 views

Original Research

Published on 12 Aug 2024

The integrated analysis of gut microbiota and metabolome revealed steroid hormone biosynthesis is a critical pathway in liver regeneration after 2/3 partial hepatectomy

in Translational Pharmacology

Runbin Sun
Fei Fei
Dandan Jin
Haoyi Yang
Zhi Xu
Bei Cao
Juan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407401

1,043 views

Clinical Trial

Published on 12 Aug 2024

No QTc prolongation with CDK 4/6 inhibitor FCN-437c: results of a concentration-QTc analysis from a dedicated study in adult healthy subjects

in Translational Pharmacology

Lin Zhao
Yi Sun
Xiaoran Yang
Ling Tian
Lize Li
Fangfang Wang
Xiaoye Niu
Lei Diao
Haiyan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433663

793 views

Review

Published on 05 Aug 2024

Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment

in Translational Pharmacology

Monika Chomczyk
Luca Gazzola
Shubhankar Dash
Patryk Firmanty
Binsah S. George
Vakul Mohanty
Hussein A. Abbas
Natalia Baran

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409210

2,180 views

Perspective

Published on 02 Aug 2024

Artificial intelligence integration in the drug lifecycle and in regulatory science: policy implications, challenges and opportunities

in Translational Pharmacology

Wahiba Oualikene-Gonin
Marie-Christine Jaulent
Jean-Pierre Thierry
Sofia Oliveira-Martins
Laetitia Belgodère
Patrick Maison
Joël Ankri
The Scientific Advisory Board of ANSM

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437167

2,389 views

Editorial

Published on 30 Jul 2024

Editorial: Pharmacoinformatics: new developments and challenges in drug design

in Translational Pharmacology

David Ramírez
Rafael Peláez
Carlos F. Lagos
José L. Medina-Franco

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462070

739 views

Original Research

Published on 30 Jul 2024

The 5HT4R agonist velusetrag efficacy on neuropathic chronic intestinal pseudo-obstruction in PrP-SCA7-92Q transgenic mice

in Translational Pharmacology

Yongqiang Liu
Yunfei Wu
Dewan Ren
Yulong Tao
Fangyi Mai
Jingyi Zhu
Xiang Li
Emanuela Colla
Maria Grimaldi
Roberto Giovannini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1411642

943 views

Original Research

Published on 30 Jul 2024

Nanoparticles (NPs)-mediated lncMALAT1 silencing to reverse cisplatin resistance for effective hepatocellular carcinoma therapy

in Translational Pharmacology

Ting Wang
Qianyao Li
Rui Xu
Zixuan Zhao
Qi Sun
Xiaoding Xu
Rong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437071

1,151 views

Original Research

Published on 29 Jul 2024

Causal gene identification using mitochondria-associated genome-wide mendelian randomization in atrial fibrillation

in Translational Pharmacology

Ying Chen
Bingxun Li
Hongxuan Xu
Lin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439816

1,564 views

Original Research

Published on 25 Jul 2024

When to consider intra-target microdosing: physiologically based pharmacokinetic modeling approach to quantitatively identify key factors for observing target engagement

in Translational Pharmacology

Yasunori Aoki
Malcom Rowland
Yuichi Sugiyama

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1366160

1,037 views

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Articles

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection (ALND)

Unveiling novel serum biomarkers in intrahepatic cholangiocarcinoma: a pilot proteomic exploration

The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine

Advances in research on potential therapeutic approaches for Niemann-Pick C1 disease

Pharmacokinetics and safety profiles of beinaglutide injection, a recombinant human GLP-1, in adults with overweight/obesity: results from a phase I clinical trial

In vitro evidence of antioxidant and anti-inflammatory effects of a new nutraceutical formulation explains benefits in a clinical setting of COPD patients

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius

The integrated analysis of gut microbiota and metabolome revealed steroid hormone biosynthesis is a critical pathway in liver regeneration after 2/3 partial hepatectomy

No QTc prolongation with CDK 4/6 inhibitor FCN-437c: results of a concentration-QTc analysis from a dedicated study in adult healthy subjects

Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment

Artificial intelligence integration in the drug lifecycle and in regulatory science: policy implications, challenges and opportunities

Editorial: Pharmacoinformatics: new developments and challenges in drug design

The 5HT4R agonist velusetrag efficacy on neuropathic chronic intestinal pseudo-obstruction in PrP-SCA7-92Q transgenic mice

Nanoparticles (NPs)-mediated lncMALAT1 silencing to reverse cisplatin resistance for effective hepatocellular carcinoma therapy

Causal gene identification using mitochondria-associated genome-wide mendelian randomization in atrial fibrillation

When to consider intra-target microdosing: physiologically based pharmacokinetic modeling approach to quantitatively identify key factors for observing target engagement