Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 26 Sep 2025

Comparison of oliceridine and sufentanil in patient - controlled intravenous analgesia for post - thoracoscopic nausea and vomiting: a prospective, double - blind, randomized controlled trial

in Translational Pharmacology

Yuxiang Meng
Sumin Yuan
Hengrui Zhang
Zijie Ling
Chenyang Shi
Yang Niu
Li Zhang
Zhibiao Xu
Yujun Liu
Kang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576154

2,983 views
1 citation

Original Research

Published on 25 Sep 2025

Bio-hybrid scaffolds combining polyvinyl alcohol and decellularized articular cartilage for the treatment of focal chondral lesions in hemophilic patients

in Translational Pharmacology

Silvia Barbon
Marta Confalonieri
Elena Stocco
Alice D’Osualdo
Martina Contran
Pier Paolo Parnigotto
Raffaele De Caro
Silvia Todros
Veronica Macchi
Piero G. Pavan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1650467

1,962 views

Mini Review

Published on 22 Sep 2025

The physiological and pharmaceutical roles of MCTs and other ingredients in intravenous emulsions containing omega-3 enriched fish oil designed to mitigate cytokine release syndrome

in Translational Pharmacology

David F. Driscoll
Bruce R. Bistrian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673290

2,332 views

Review

Published on 18 Sep 2025

Multifunctional PLGA nanosystems: enabling integrated diagnostic and therapeutic strategies

in Translational Pharmacology

Yue Li
Tao Tao
Yao Xiong
Weiyu Guo
Yangbiao Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1670397

3,033 views
4 citations

Review

Published on 18 Sep 2025

Retrospective evaluation of resident pharmacists’ services in a liver intensive care unit: a single-center experience

in Translational Pharmacology

Huijie Meng
Zhaoshuai Ji
Zhenyu Zhang
Yuanyuan Liu
Fang Li
Jing Tang
Guangmeng Nie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583818

1,652 views

Original Research

Published on 17 Sep 2025

Clinical development prospects of siRNA drugs for tumor therapy: analysis of clinical trial registration data from 2004 to 2024

in Translational Pharmacology

Cai-E. Wang
Delong Zhen
Lukui Yang
Guifang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1637958

4,121 views

Original Research

Published on 16 Sep 2025

Safety, tolerability, pharmacokinetics, immunogenicity and pharmacodynamics of 9MW1911, an anti-ST2 monoclonal antibody: results from a first-in-human phase 1 study

in Translational Pharmacology

Qian Zhao
Qian Li
Yucan Wang
Li Li
Xue Zhao
Ni Wu
Diyi Fu
Danfeng Yin
Jing Feng
Zhitian Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1647816

3,012 views

Original Research

Published on 15 Sep 2025

Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3

in Translational Pharmacology

Adina-Gabriela Vasilescu
Andrei-Mihai Vasilescu
Livia Elena Sima
Natalia Baran
Ștefan-Eugen Szedlacsek

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673427

2,191 views

Original Research

Published on 12 Sep 2025

Effect of structure and composition of cationic liposomes on the delivery of siRNA in vitro and in vivo

in Translational Pharmacology

Daniil V. Gladkikh
Elena V. Shmendel
Darya M. Makarova
Mikhail A. Maslov
Marina A. Zenkova
Elena L. Chernolovskaya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656671

2,639 views

Original Research

Published on 12 Sep 2025

A novel cytotoxic anti-B7-H3 affibody with therapeutic potential in acute myeloid leukemia

in Translational Pharmacology

Andrei-Mihai Vasilescu
Adina-Gabriela Vasilescu
Livia Elena Sima
Cristian V. A. Munteanu
Natalia Baran
Ștefan-Eugen Szedlacsek

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684226

2,750 views

Brief Research Report

Published on 11 Sep 2025

Buprenorphine and cannabidiol co-administration reduces survival in a mouse model of orthopedic trauma

in Translational Pharmacology

Caroline Bouchard
Geneviève Frégeau
Ian Massé
Louis De Beaumont

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683842

2,022 views

Case Report

Published on 11 Sep 2025

Occupational toxic encephalopathy due to 1,2-dichloroethane exposure: a case series

in Translational Pharmacology

Tongyao Li
Wensi Hu
Xia Rong
Ping Yang
Yu Du
Songbai He
Haibo Tang
Linna Luo
Lin Shi
Junzhao Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542156

1,856 views
3 citations

Review

Published on 08 Sep 2025

Efficacy and safety of pregabalin in the management of low back pain: a comprehensive meta-analysis

in Translational Pharmacology

Carlos Cordero‐García
Judith Sánchez‐Raya
Tamara L. Rodríguez‐Araya
María Dolores López‐Alarcón
Eva Trillo‐Calvo
Jerónimo Balsalobre‐Aznar
Maria Pérez‐Páramo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1659531

5,290 views

Original Research

Published on 03 Sep 2025

Differential carbon source utilization drives metabolic state and resuscitation in antibiotic-tolerant persister cells

in Translational Pharmacology

Yufei Sun
Sweta Roy
Qingbo Yang
Yinjie J. Tang
Dacheng Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634627

2,483 views
1 citation

Original Research

Published on 02 Sep 2025

Parthanatos drives cognitive decline in repeated brain trauma: MSC-derived exosomes as a novel therapeutic strategy

in Translational Pharmacology

Heba Mohammed Refat M. Selim
Amira A. El-Gazar
Dalaal M. Abdallah
Hagar B. Abo-Zalam
Ghada M. Ragab
Ahmed N. Abdallah
Rabab A. El-Gazar
Sultan Alshehri
Einas M. Yousef
Rayan Ballal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1622018

2,764 views
1 citation

Original Research

Published on 29 Aug 2025

c-MYC mRNA destabilization inhibited lethal pancreatic cancer in vivo with significant survival outcomes

in Translational Pharmacology

Jigme P. Dorji
Queenie Chen
Sandali G. Perera
Fizza Aijaz
Petvy Li
Tanjina Sania
Hiroshi Matsui
Chidiebere U. Awah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630476

2,837 views

Original Research

Published on 28 Aug 2025

Pharmacokinetics and safety of highly variable nitroglycerin lingual spray (NLS) versus US-licensed nitroglycerin lingual spray reference product (Nitrolingual®): a randomized, four-cycle, four-sequence, partially replicated crossover Phase I bioequivalence clinical trial

in Translational Pharmacology

Yingying Fang
Lu Qi
Yu Wang
Chunyu Han
Qian Zhang
Xiaoyun Liu
Ju Liu
Xiaoqiang Cheng
Yinjuan Li
Yan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631341

1,795 views

Editorial

Published on 28 Aug 2025

Editorial: Emerging horizons of metformin: exploring recent advances and addressing challenges in research and clinical utilization

in Translational Pharmacology

Charupong Saengboonmee
Mehrnaz Abbasi
Agnieszka Śliwińska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1674641

2,480 views

Original Research

Published on 28 Aug 2025

Investigating the feasibility of machine learning to guide personalized red blood cell (RBC) transfusion: analyzing the heterogeneity of RBC transfusion in septic patients with hemoglobin levels of 7–9 g/dL based on the causal forest model

in Translational Pharmacology

Penglei Yang
Jun Yuan
Jie He
Lina Yu
Xue Gu
Xizhen Ding
Qihong Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615618

2,124 views
1 citation

Review

Published on 25 Aug 2025

Targeted photodynamic therapy: enhancing efficacy through specific organelle engagement

in Translational Pharmacology

Jiawen Tao
Zhifei Yuan
Mengjiao Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667812

4,297 views
7 citations

Original Research

Published on 21 Aug 2025

Locked nucleic acid-modified antisense oligonucleotides attenuate scar hyperplasia through targeted inhibition of CTGF

in Translational Pharmacology

Jinhe Li
Xi Wu
Ying Yang
Ruiqi Mao
Zherui Li
Xiujun Zhang
Wenguo Wei
Wendi Wang
Hailong Li
Honggang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1623640

2,396 views

Original Research

Published on 21 Aug 2025

Effect of ketamine on cellular immunity and inflammation in patients who undergo laparoscopic colon cancer surgery: a retrospective study

in Translational Pharmacology

Jiajia Ji
Haiping Zhang
Lixia Zhou
Chunlan Fan
Ligen Dai
Shaolei Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562122

1,991 views

Original Research

Published on 18 Aug 2025

Published population pharmacokinetic models of mycophenolate sodium: a systematic review and external evaluation in a Chinese sample of renal transplant recipients

in Translational Pharmacology

Tong Gao
Wen Xu
Xiao Li
Qie Guo
Donghua Liu
Xiaolei Zhang
Ping Leng
Jialin Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632568

1,684 views
1 citation

Original Research

Published on 15 Aug 2025

Global research trends on ALK-TKIs in non-small cell lung cancer: a bibliometric analysis

in Translational Pharmacology

Yafeng Liu
Zhaojin Han
Yujia Li
Pengfei Zhang
Qiushi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665174

2,967 views

1,097 articles

articles

Comparison of oliceridine and sufentanil in patient - controlled intravenous analgesia for post - thoracoscopic nausea and vomiting: a prospective, double - blind, randomized controlled trial

Bio-hybrid scaffolds combining polyvinyl alcohol and decellularized articular cartilage for the treatment of focal chondral lesions in hemophilic patients

The physiological and pharmaceutical roles of MCTs and other ingredients in intravenous emulsions containing omega-3 enriched fish oil designed to mitigate cytokine release syndrome

Multifunctional PLGA nanosystems: enabling integrated diagnostic and therapeutic strategies

Retrospective evaluation of resident pharmacists’ services in a liver intensive care unit: a single-center experience

Clinical development prospects of siRNA drugs for tumor therapy: analysis of clinical trial registration data from 2004 to 2024

Safety, tolerability, pharmacokinetics, immunogenicity and pharmacodynamics of 9MW1911, an anti-ST2 monoclonal antibody: results from a first-in-human phase 1 study

Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3

Effect of structure and composition of cationic liposomes on the delivery of siRNA in vitro and in vivo

A novel cytotoxic anti-B7-H3 affibody with therapeutic potential in acute myeloid leukemia

Buprenorphine and cannabidiol co-administration reduces survival in a mouse model of orthopedic trauma

Occupational toxic encephalopathy due to 1,2-dichloroethane exposure: a case series

Efficacy and safety of pregabalin in the management of low back pain: a comprehensive meta-analysis

Differential carbon source utilization drives metabolic state and resuscitation in antibiotic-tolerant persister cells

Parthanatos drives cognitive decline in repeated brain trauma: MSC-derived exosomes as a novel therapeutic strategy

c-MYC mRNA destabilization inhibited lethal pancreatic cancer in vivo with significant survival outcomes

Pharmacokinetics and safety of highly variable nitroglycerin lingual spray (NLS) versus US-licensed nitroglycerin lingual spray reference product (Nitrolingual®): a randomized, four-cycle, four-sequence, partially replicated crossover Phase I bioequivalence clinical trial

Editorial: Emerging horizons of metformin: exploring recent advances and addressing challenges in research and clinical utilization

Investigating the feasibility of machine learning to guide personalized red blood cell (RBC) transfusion: analyzing the heterogeneity of RBC transfusion in septic patients with hemoglobin levels of 7–9 g/dL based on the causal forest model

Targeted photodynamic therapy: enhancing efficacy through specific organelle engagement

Locked nucleic acid-modified antisense oligonucleotides attenuate scar hyperplasia through targeted inhibition of CTGF

Effect of ketamine on cellular immunity and inflammation in patients who undergo laparoscopic colon cancer surgery: a retrospective study

Published population pharmacokinetic models of mycophenolate sodium: a systematic review and external evaluation in a Chinese sample of renal transplant recipients

Global research trends on ALK-TKIs in non-small cell lung cancer: a bibliometric analysis