Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 12 Aug 2024

The integrated analysis of gut microbiota and metabolome revealed steroid hormone biosynthesis is a critical pathway in liver regeneration after 2/3 partial hepatectomy

in Translational Pharmacology

Runbin Sun
Fei Fei
Dandan Jin
Haoyi Yang
Zhi Xu
Bei Cao
Juan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407401

1,535 views
2 citations

Clinical Trial

Published on 12 Aug 2024

No QTc prolongation with CDK 4/6 inhibitor FCN-437c: results of a concentration-QTc analysis from a dedicated study in adult healthy subjects

in Translational Pharmacology

Lin Zhao
Yi Sun
Xiaoran Yang
Ling Tian
Lize Li
Fangfang Wang
Xiaoye Niu
Lei Diao
Haiyan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433663

1,455 views

Review

Published on 05 Aug 2024

Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment

in Translational Pharmacology

Monika Chomczyk
Luca Gazzola
Shubhankar Dash
Patryk Firmanty
Binsah S. George
Vakul Mohanty
Hussein A. Abbas
Natalia Baran

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409210

3,670 views
2 citations

Perspective

Published on 02 Aug 2024

Artificial intelligence integration in the drug lifecycle and in regulatory science: policy implications, challenges and opportunities

in Translational Pharmacology

Wahiba Oualikene-Gonin
Marie-Christine Jaulent
Jean-Pierre Thierry
Sofia Oliveira-Martins
Laetitia Belgodère
Patrick Maison
Joël Ankri
The Scientific Advisory Board of ANSM

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437167

4,574 views
3 citations

Editorial

Published on 30 Jul 2024

Editorial: Pharmacoinformatics: new developments and challenges in drug design

in Translational Pharmacology

David Ramírez
Rafael Peláez
Carlos F. Lagos
José L. Medina-Franco

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462070

1,207 views

Original Research

Published on 30 Jul 2024

The 5HT4R agonist velusetrag efficacy on neuropathic chronic intestinal pseudo-obstruction in PrP-SCA7-92Q transgenic mice

in Translational Pharmacology

Yongqiang Liu
Yunfei Wu
Dewan Ren
Yulong Tao
Fangyi Mai
Jingyi Zhu
Xiang Li
Emanuela Colla
Maria Grimaldi
Roberto Giovannini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1411642

1,545 views
1 citation

Original Research

Published on 30 Jul 2024

Nanoparticles (NPs)-mediated lncMALAT1 silencing to reverse cisplatin resistance for effective hepatocellular carcinoma therapy

in Translational Pharmacology

Ting Wang
Qianyao Li
Rui Xu
Zixuan Zhao
Qi Sun
Xiaoding Xu
Rong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437071

1,710 views
3 citations

Original Research

Published on 29 Jul 2024

Causal gene identification using mitochondria-associated genome-wide mendelian randomization in atrial fibrillation

in Translational Pharmacology

Ying Chen
Bingxun Li
Hongxuan Xu
Lin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439816

2,408 views

Original Research

Published on 25 Jul 2024

When to consider intra-target microdosing: physiologically based pharmacokinetic modeling approach to quantitatively identify key factors for observing target engagement

in Translational Pharmacology

Yasunori Aoki
Malcom Rowland
Yuichi Sugiyama

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1366160

1,407 views

Review

Published on 25 Jul 2024

Ligand-conjugated multiwalled carbon nanotubes for cancer targeted drug delivery

in Translational Pharmacology

Chanchal Kiran Thakur
Chandrabose Karthikeyan
Charles R. Ashby
Rabin Neupane
Vishal Singh
R. Jayachandra Babu
N. S. Hari Narayana Moorthy
Amit K. Tiwari

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1417399

2,855 views
5 citations

Review

Published on 25 Jul 2024

Bibliometric and visualized analysis of ultrasound combined with microbubble therapy technology from 2009 to 2023

in Translational Pharmacology

Bin Tu
Yan Li
Wen Wen
Jian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1418142

1,735 views

Original Research

Published on 22 Jul 2024

Pan-cancer analyses reveal the molecular and clinical characteristics of TET family members and suggests that TET3 maybe a potential therapeutic target

in Translational Pharmacology

Chunyan Zhang
Jie Zheng
Jin Liu
Yanxia Li
Guoqiang Xing
Shupeng Zhang
Hekai Chen
Jian Wang
Zhijiang Shao
Yongyuan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1418456

1,873 views
1 citation

Review

Published on 18 Jul 2024

Bibliometric analysis of vitamin D and obesity research over the period 2000 to 2023

in Translational Pharmacology

Xudong Song
Senhua Qin
Shuxin Chen
Can Zhang
Lin Lin
Ziyi Song

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1445061

2,847 views
3 citations

Original Research

Published on 18 Jul 2024

Identifying potential therapeutic targets in lung adenocarcinoma: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization

in Translational Pharmacology

Youpeng Chen
Enzhong Li
Zhenglin Chang
Tingting Zhang
Zhenfeng Song
Haojie Wu
Zhangkai J. Cheng
Baoqing Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433147

3,653 views

Editorial

Published on 16 Jul 2024

Editorial: Incorporating Phase 0 microdosing as a powerful tool into a new vision of drug development

in Translational Pharmacology

H. Markus Weiss
Yuichi Sugiyama
Esther van Duijn

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1455643

918 views

Clinical Trial

Published on 15 Jul 2024

A phase 1, randomized, double-blind, placebo-controlled, dose escalation study to evaluate the safety, tolerability, pharmacokinetics and immunogenicity of SHR-1905, a long-acting anti-thymic stromal lymphopoietin antibody, in healthy subjects

in Translational Pharmacology

Yue Fei
Na Li
Weilin Qian
Yang Fan
Yu Shen
Quanren Wang
Kristi McLendon
Kai Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1400696

4,379 views
1 citation