Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 19 Mar 2025

Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis

in Translational Pharmacology

Montana Young
Ryan P. Ceddia
Analisa Thompson-Gray
David Reyes
Jackson B. Cassada
Julio E. Ayala
Owen P. McGuinness
Sheila Collins
Heidi E. Hamm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544456

2,678 views

Original Research

Published on 19 Mar 2025

Metformin as a disease-modifying therapy in osteoarthritis: bridging metabolism and joint health

in Translational Pharmacology

Iryna Halabitska
Pavlo Petakh
Oleksandr Kamyshnyi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567544

4,339 views
8 citations

Review

Published on 19 Mar 2025

Functional tumor-derived exosomes in NSCLC progression and clinical implications

in Translational Pharmacology

Yuxin Gao
Jun Xie
Zhenya Yang
Mengxi Li
Hongfan Yuan
Rui Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1485661

3,789 views
3 citations

Editorial

Published on 14 Mar 2025

Editorial: The potential of transferrin as a drug target and drug delivery system

in Translational Pharmacology

Patricia Carrilho
Sidharth Chopra
Mallikarjuna Rao Pichika
Robert E. Fleming
Nermi L. Parrow

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584190

3,209 views
2 citations

Original Research

Published on 05 Mar 2025

Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE−/− mice through the miR-34a/FGF-21 axis

in Translational Pharmacology

Ning Tao
Zhichao He
Han Duan
Liang Wang
Jing Yi
Jingyuan Shao
Lin Lv
Junzhao Duan
Hu Cao
Xiwen Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562321

2,375 views

Brief Research Report

Published on 03 Mar 2025

SysNatMed: rational natural medicine discovery by systems genetics

in Translational Pharmacology

Chang-Qing Ye
Jie Leng
Meng-Yuan Jin
Yuan-Dong Meng
Zi-Yi Zhao
Fan-Xing Meng
Xuan Xu
Sha-Sha Fan
Hong-Bin Luo
Xiang-Yu Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1496061

2,723 views
1 citation

Original Research

Published on 26 Feb 2025

Knowledge structure and dynamic evolution of nanomedicine in liver cancer research: a scientometric analysis and visualization

in Translational Pharmacology

Shaodong Li
Dapeng Cui
Bo Shao
Zhenhua Kang
Guoqiang Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509259

2,879 views

Review

Published on 26 Feb 2025

Muscle loss in cancer cachexia: what is the basis for nutritional support?

in Translational Pharmacology

Jaline Faiad
Márcia Fábia Andrade
Gabriela de Castro
Joyce de Resende
Marina Coêlho
Giovana Aquino
Marilia Seelaender

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519278

5,724 views
7 citations

Original Research

Published on 17 Feb 2025

A double-layer PLGA/CoI-MeHA tissue engineering scaffold for urethral reconstruction

in Translational Pharmacology

Mingyang Chang
Qinyuan Tan
Ge Bian
Ming Zhang
Jianing Lv
Junjie Su
Xiaoqing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555183

2,474 views
2 citations

Review

Published on 13 Feb 2025

Exploring the application of metal-based photothermal agents in photothermal therapy combined with immune checkpoint therapy

in Translational Pharmacology

Bin Xie
ZhiRong Xiao
JiaBao Ling
Yichao Peng
Tianfeng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553158

2,835 views
3 citations

Original Research

Published on 12 Feb 2025

Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women

in Translational Pharmacology

Katja Graf
José Martin Murrieta-Coxca
Tobias Vogt
Sophie Besser
Daria Geilen
Tim Kaden
Anne-Katrin Bothe
Diana Maria Morales-Prieto
Behnam Amiri
Stephan Schaller

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528748

9,853 views
10 citations

Review

Published on 12 Feb 2025

Advances in hydrogel for diagnosis and treatment for Parkinson’s disease

in Translational Pharmacology

Peining Zhu
Zenghui Zhao
Yufei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552586

4,332 views
2 citations

Brief Research Report

Published on 31 Jan 2025

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

in Translational Pharmacology

Valentina N. Nikolić
Milan Stefanović
Dejan Mitić
Slavica Sunarić
Vladana Stojiljkovic
Hristina Trajković
Aleksandra Ignjatović
Dragana Stokanović

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505022

2,801 views
1 citation

Mini Review

Published on 22 Jan 2025

Brief summary of the regulatory frameworks of regenerative medicine therapies

in Translational Pharmacology

Jinah Yoon
Sukhyang Lee
Min Jung Kim
Jung-Hyun Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486812

9,011 views
13 citations

Brief Research Report

Published on 16 Jan 2025

Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses

in Translational Pharmacology

Yu-Wei Lin
Anna Largajolli
A. Yin Edwards
S. Y. Amy Cheung
Kashyap Patel
Stefanie Hennig

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1487062

3,039 views
2 citations

Original Research

Published on 09 Jan 2025

Targeted lipidomics analysis of possible molecular mechanisms of lipid changes in temporal lobe epilepsy models

in Translational Pharmacology

Huaiyu Sun
Xuewei Li
Zhiqing Chen
Hongmei Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1531524

3,164 views
3 citations

Review

Published on 06 Jan 2025

Polymer-based antimicrobial strategies for periodontitis

in Translational Pharmacology

Jiajia Chen
Shujun Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1533964

3,127 views
4 citations

Original Research

Published on 06 Jan 2025

Astragaloside IV alleviates GDM via regulating gut microbiota and gut microbiota metabolomic

in Translational Pharmacology

Fengge Wang
Yongning Zhu
Hua Shu
Xiaoyun Zhang
Liting Duan
Dongmei Man
Yanping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431240

3,517 views
2 citations

Review

Published on 06 Jan 2025

Applications of polymeric nanoparticles in drug delivery for glioblastoma

in Translational Pharmacology

Bin Tan
Shuhan Liu
Feng Wang
Ying Yu
Tianmeng Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1519479

5,179 views
18 citations

Editorial

Published on 03 Jan 2025

Editorial: Advances in mitochondria-targeting in drug development for common disorders

in Translational Pharmacology

Mundla Srilatha
Ganji Purnachandra Nagaraju

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1520126

1,579 views

Original Research

Published on 03 Jan 2025

Tumor microenvironment–responsive and modulatory manganese-based nanoenzyme for enhanced tumor immunotherapy

in Translational Pharmacology

Qi Yang
Qiong Wu
Haiyan Liu
Jiandong Wu
Feng Ma
Xiaofeng Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1518983

3,167 views
5 citations

Review

Published on 23 Dec 2024

Comprehensive review on neprilysin (NEP) inhibitors: design, structure-activity relationships, and clinical applications

in Translational Pharmacology

Xinyue Zhang
Chun Hu
Erkang Tian
Yanxin Shen
Wei Liu
Juan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1501407

7,604 views
8 citations

Clinical Trial

Published on 18 Dec 2024

Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study

in Translational Pharmacology

Chenan Liu
Tong Liu
Yaping Wei
Jinyu Shi
Li Deng
Mengmeng Song
Hanping Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1507125

3,405 views

Original Research

Published on 16 Dec 2024

In vitro elimination of antimicrobials during ADVanced Organ Support hemodialysis

in Translational Pharmacology

Christina König
Otto Frey
Susanne Himmelein
Lisa Mulack
Alexander Brinkmann
Aritz Perez Ruiz de Garibay
Tobias Bingold

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1447511

2,387 views
2 citations