Frontiers in Pharmacology | Translational Pharmacology

Mini Review

Published on 18 Mar 2024

The application of Phase 0 and microtracer approaches in early clinical development: past, present, and future

in Translational Pharmacology

A. F. Roffel
E.-J. van Hoogdalem

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1369079

2,272 views
1 citation

Original Research

Published on 07 Mar 2024

Assessing the relative contribution of CYP3A-and P-gp-mediated pathways to the overall disposition and drug-drug interaction of dabigatran etexilate using a comprehensive mechanistic physiological-based pharmacokinetic model

in Translational Pharmacology

Udomsak Udomnilobol
Wilasinee Dunkoksung
Watchara Sakares
Suree Jianmongkol
Thomayant Prueksaritanont

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1356273

1,946 views
1 citation

Review

Published on 04 Mar 2024

Pathophysiological aspects of transferrin-A potential nano-based drug delivery signaling molecule in therapeutic target for varied diseases

in Translational Pharmacology

Chang Li
Liya Zhou
Xunzhe Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1342181

3,842 views
10 citations

Original Research

Published on 04 Mar 2024

Synthesis, biological and computational evaluation of novel cyanomethyl vinyl ether derivatives

in Translational Pharmacology

Endika Martín-Encinas
María Fuertes
Samuel Delgado-Hernández
Fernando García-Tellado
David Tejedor
Concepción Alonso

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1344042

1,355 views
1 citation

Original Research

Published on 01 Mar 2024

Evaluation of binding mechanism of dietary phytochemical, capsaicin, with human transferrin: targeting neurodegenerative diseases therapeutics

in Translational Pharmacology

Mohammed Alrouji
Fahad A. Alhumaydhi
Kumar Venkatesan
Sharaf E. Sharaf
Moyad Shahwan
Anas Shamsi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1348128

1,836 views
1 citation

Original Research

Published on 23 Feb 2024

Quantification of stimulus-evoked tactile allodynia in free moving mice by the chainmail sensitivity test

in Translational Pharmacology

Yildirim Ozdemir
Kazuo Nakamoto
Bruno Boivin
Daniel Bullock
Nick A. Andrews
Rafael González-Cano
Michael Costigan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352464

2,416 views

Perspective

Published on 22 Feb 2024

Exploiting the damaging effects of ROS for therapeutic use by deactivating cell-free chromatin: the alchemy of resveratrol and copper

in Translational Pharmacology

Indraneel Mittra

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1345786

2,578 views
4 citations

Review

Published on 13 Feb 2024

Exploring the efficacy and safety of Ambroxol in Gaucher disease: an overview of clinical studies

in Translational Pharmacology

Feda E. Mohamed
Fatma Al-Jasmi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1335058

6,931 views
6 citations

Review

Published on 08 Feb 2024

A comprehensive review of the literature on CD10: its function, clinical application, and prospects

in Translational Pharmacology

Shudong Wang
Yinghui Xiao
Xingna An
Ling Luo
Kejian Gong
Dehai Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1336310

6,870 views
2 citations

Review

Published on 08 Feb 2024

Update on the advances and challenges in bioequivalence testing methods for complex topical generic products

in Translational Pharmacology

Nedaa Alomari
Waleed Alhussaini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1330712

3,490 views
4 citations

Original Research

Published on 07 Feb 2024

Prediction of drug–disease associations based on reinforcement symmetric metric learning and graph convolution network

in Translational Pharmacology

Huimin Luo
Chunli Zhu
Jianlin Wang
Ge Zhang
Junwei Luo
Chaokun Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1337764

2,158 views
4 citations

Clinical Trial

Published on 07 Feb 2024

Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

in Translational Pharmacology

Joan Perelló
Joan Alberti
Juan Vicente Torres
Miguel D. Ferrer
M. Mar Perez
Firas Bassissi
Alex Gold
Paolo Raggi
Glenn M. Chertow
Carolina Salcedo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1325186

1,544 views

Original Research

Published on 06 Feb 2024

Prevalence and clinical significance of potential drug-drug interactions among lung transplant patients

in Translational Pharmacology

Jiali Zhang
Danyi Ma
Meng Chen
Yanting Hu
Xveying Chen
Jingyu Chen
Man Huang
Haibin Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1308260

1,947 views
1 citation

Original Research

Published on 26 Jan 2024

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

in Translational Pharmacology

Adele Moatti
Shannon Connard
Novietta De Britto
William A. Dunn
Srishti Rastogi
Mani Rai
Lauren V. Schnabel
Frances S. Ligler
Kendall A. Hutson
Douglas C. Fitzpatrick

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1348172

3,302 views
5 citations

Clinical Trial

Published on 25 Jan 2024

Effect of dexmedetomidine on postoperative nausea and vomiting in female patients undergoing radical thoracoscopic lung cancer resection

in Translational Pharmacology

Haipeng Zhu
Shichao Wang
Ruohan Wang
Bing Li
Jiaqiang Zhang
Wei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353620

1,703 views
5 citations

Clinical Trial

Published on 19 Jan 2024

Towards a better detection of patients at-risk of linezolid toxicity in clinical practice: a prospective study in three Belgian hospital centers

in Translational Pharmacology

Hélène Thirot
David Fage
Antonia Leonhardt
Philippe Clevenbergh
Tatiana Besse-Hammer
Jean Cyr Yombi
Olivier Cornu
Caroline Briquet
Maya Hites
Frédérique Jacobs

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1310309

2,919 views
3 citations