Frontiers in Pharmacology

Original Research

Published on 06 Jan 2025

pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties

Carlos Coll-Díez
Ana Marcela Giudici
Alberto Potenza
José Manuel González-Ros
José Antonio Poveda

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499383

1,887 views

Review

Published on 06 Jan 2025

Plant and marine-derived natural products: sustainable pathways for future drug discovery and therapeutic development

Muhammad Ahmad
Maleha Tahir
Zibin Hong
Muhammad Anjum Zia
Hamza Rafeeq
Muhammad Shaheez Ahmad
Saif ur Rehman
Junming Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1497668

13,109 views
30 citations

Original Research

Published on 06 Jan 2025

Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4

Mengjiao Xue
Yiwei Tian
Hua Zhang
Shijie Dai
Yangsheng Wu
Juan Jin
Jian Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1508312

3,187 views
3 citations

Review

Published on 06 Jan 2025

Regulation and therapy: the role of ferroptosis in DLBCL

Yifan Wang
Zhengmei He
Xinyu Dong
Yiming Yao
Qiuni Chen
Yuye Shi
Yuan Deng
Quane Zhang
Liang Yu
Chunling Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458412

3,378 views

Original Research

Published on 06 Jan 2025

Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter?

Agnieszka Zelek-Molik
Anna Gądek-Michalska
Michał Wilczkowski
Adam Bielawski
Katarzyna Maziarz
Grzegorz Kreiner
Irena Nalepa

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451895

1,871 views
3 citations

Original Research

Published on 06 Jan 2025

Drug-induced urinary retention: a real-world pharmacovigilance study using FDA and Canada vigilance databases

Xianyu Dai
Kai Yu
Yu Chang
Yuchuan Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466875

5,863 views
3 citations

Original Research

Published on 06 Jan 2025

The efficacy and safety of half-dose glucocorticoids combined with rituximab versus high-dose glucocorticoids for initial treatment of minimal change disease: a single-center experience

Xueting Li
Peng Yan
Lu Zhang
Wei Qiao
Zhengbiao Xue
Xiangdong Fang
Ben Ke
Shuying Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1403562

2,760 views
3 citations

Original Research

Published on 06 Jan 2025

CPT1 deficiency blocks autophagic flux to promote lipid accumulation induced by co-exposure to polystyrene microplastic and cadmium

Zhixuan Chen
Huayi Qu
Jian Sun
Tao Wang
Yan Yuan
Jianhong Gu
Jianchun Bian
Zongping Liu
Hui Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1533188

2,387 views
1 citation

Editorial

Published on 06 Jan 2025

Editorial: Novel pharmacological targets and strategies to treat neglected global diseases (NGDs): an LMIC perspective

Kishor M. Wasan
Somia Iqtadar
Celestin Nzanzu Mudogo
Miguel Angel Chávez-Fumagalli

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1527705

1,511 views
2 citations

Methods

Published on 06 Jan 2025

Liquid chromatography-tandem mass spectrometry for the quantification of ripretinib and its metabolites DP-5439 in human plasma

Jiahui Lin
Aiting Jiang
Juntao Zheng
Jingjing Wu
Hao Li
Shirong Cai
Yulong He
Xiao Chen
Guoping Zhong
Ke-Jing Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506931

1,886 views
2 citations

Original Research

Published on 06 Jan 2025

Median effective dose of remimazolam combined with sufentanil for inhibiting laryngeal mask airway insertion responses in children of different ages

Hongyun Li
Jinxia Wang
Rong Wei
Yan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506209

1,942 views
4 citations

Original Research

Published on 06 Jan 2025

Accurate identification of snoRNA targets using variational graph autoencoder to advance the redevelopment of traditional medicines

Zhina Wang
Yangyuan Chen
Hongming Ma
Hong Gao
Yangbin Zhu
Hongwu Wang
Nan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1529128

2,103 views
2 citations

Original Research

Published on 03 Jan 2025

Ceftriaxone-associated dysbiosis decreases voriconazole bioavailability by upregulating intestinal P-glycoprotein expression through activation of the Nrf2-mediated signalling pathway

Xiaokang Wang
Chunxiao Ye
Xixiao Yang
Maoxun Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1522271

1,915 views
3 citations

Original Research

Published on 03 Jan 2025

Protein-ligand binding affinity prediction using multi-instance learning with docking structures

Hyojin Kim
Heesung Shim
Aditya Ranganath
Stewart He
Garrett Stevenson
Jonathan E. Allen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1518875

5,125 views
5 citations

Original Research

Published on 03 Jan 2025

Inappropriate prescribing of drugs for peptic ulcer and gastro-esophageal reflux disease remains a matter of concern: Results from the LAPTOP-PPI cluster randomized trial

Manuela Casula
Ilaria Ardoino
Laura Pierini
Lara Perrella
Stefano Scotti
Sara Mucherino
Valentina Orlando
Enrica Menditto
Carlotta Franchi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430879

3,161 views
1 citation

Original Research

Published on 03 Jan 2025

Effect of bromelain on ischemia-reperfusion injury in the torsion model created in polycystic and normal ovarian tissues

Sevgi Ulusoy Tangul
Taylan Onat
Demet Aydoğan Kirmizi
Zuleyha Doganyigit
Emin Kaymak
Aslı Oflamaz
Atilla Şenayli
Salih Somuncu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451592

3,112 views
3 citations

Original Research

Published on 03 Jan 2025

Integrated serum pharmacochemistry, pharmacokinetics, and network analysis to explore active components of BuShao Tiaozhi Capsule on hyperlipidemia

Ruiyin Tang
Guanlin Xiao
Yanchang Liu
Dezheng Jia
Zhihao Zeng
Canchao Jia
Dongmei Li
Yangxue Li
Jieyi Jiang
Sumei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1444967

2,045 views
1 citation

Systematic Review

Published on 03 Jan 2025

Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic review and meta-analysis

Yuanchen Lv
Zibo Hua
Xiaomei Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1511525

3,900 views
3 citations

Original Research

Published on 03 Jan 2025

Modulation of gut microbiota, up-regulation of ZO-1, and promotion of metabolism as therapeutic mechanisms of indole-3-carbinol against obesity in mice

XuWen Mao
Guliruoyi Paerhati
Yuche Wu
Lu Feng Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499142

2,779 views
8 citations

Review

Published on 03 Jan 2025

Research progress on the synthesis process, detection method, pharmacological effects and application of glycocholic acid

Jiahui Li
Chungang Zhang
Yang Wang
Minyuan Tian
Chao Xie
Heng Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1492070

3,475 views
3 citations

Original Research

Published on 03 Jan 2025

Pathogenesis-directed therapy of methylphenidate-induced oxidative heart damage in rats

Izzet Emir
Seval Bulut
Bahadır Suleyman
Renad Mammadov
Nurinisa Yucel
Betul Cicek
Gulce Naz Yazici
Durdu Altuner
Murat Gunay
Halis Suleyman

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1503032

2,655 views
2 citations

Original Research

Published on 03 Jan 2025

Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms

Min Chen
Yingying Xiao
Jijian Zheng
Peibin Zhao
Lin Cheng
Chuan Jiang
Sixie Zheng
Zheng Wang
Sijuan Sun
Lincai Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1449831

2,141 views
1 citation

Original Research

Published on 03 Jan 2025

Drug-induced Parkinson-like events: a real-world study from 2004 to the first quarter of 2024 based on FAERS

Ke Wang
Junyan Chen
Mingquan Huang
Xinhao Zeng
Xiaoqun Ren
Xiuqiong Liu
Chao Tao
Liuxuan Yang
Jinlu Shang
Meiling Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1529260

3,180 views

Original Research

Published on 03 Jan 2025

Assessing the relationships of 1,400 blood metabolites with abdominal aortic aneurysm: a Mendelian randomization study

Qian Guo
Xinghua Xu
Xiaohui Li
Yang Mao
Shengqiang Li
Yuxin Yao
Xiang Li
Yaxing Li
Jiayue Feng
Yan Shu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1514293

3,166 views
4 citations

3,490 Publications

volumes

pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties

Plant and marine-derived natural products: sustainable pathways for future drug discovery and therapeutic development

Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4

Regulation and therapy: the role of ferroptosis in DLBCL

Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter?

Drug-induced urinary retention: a real-world pharmacovigilance study using FDA and Canada vigilance databases

The efficacy and safety of half-dose glucocorticoids combined with rituximab versus high-dose glucocorticoids for initial treatment of minimal change disease: a single-center experience

CPT1 deficiency blocks autophagic flux to promote lipid accumulation induced by co-exposure to polystyrene microplastic and cadmium

Editorial: Novel pharmacological targets and strategies to treat neglected global diseases (NGDs): an LMIC perspective

Liquid chromatography-tandem mass spectrometry for the quantification of ripretinib and its metabolites DP-5439 in human plasma

Median effective dose of remimazolam combined with sufentanil for inhibiting laryngeal mask airway insertion responses in children of different ages

Accurate identification of snoRNA targets using variational graph autoencoder to advance the redevelopment of traditional medicines

Ceftriaxone-associated dysbiosis decreases voriconazole bioavailability by upregulating intestinal P-glycoprotein expression through activation of the Nrf2-mediated signalling pathway

Protein-ligand binding affinity prediction using multi-instance learning with docking structures

Inappropriate prescribing of drugs for peptic ulcer and gastro-esophageal reflux disease remains a matter of concern: Results from the LAPTOP-PPI cluster randomized trial

Effect of bromelain on ischemia-reperfusion injury in the torsion model created in polycystic and normal ovarian tissues

Integrated serum pharmacochemistry, pharmacokinetics, and network analysis to explore active components of BuShao Tiaozhi Capsule on hyperlipidemia

Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic review and meta-analysis

Modulation of gut microbiota, up-regulation of ZO-1, and promotion of metabolism as therapeutic mechanisms of indole-3-carbinol against obesity in mice

Research progress on the synthesis process, detection method, pharmacological effects and application of glycocholic acid

Pathogenesis-directed therapy of methylphenidate-induced oxidative heart damage in rats

Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms

Drug-induced Parkinson-like events: a real-world study from 2004 to the first quarter of 2024 based on FAERS

Assessing the relationships of 1,400 blood metabolites with abdominal aortic aneurysm: a Mendelian randomization study