Frontiers in Pharmacology

Original Research

Published on 02 Jan 2025

Integrated approach with UHPLC-Q-Exactive-tandem mass spectrometry, network analysis, and molecular docking to determine potential active compounds and mechanisms of Rhizoma Musae decoction in osteoarthritis treatment

Jian Zhang
Wanyan Shen
Fanzhi Liu
Hehe He
Shuquan Han
Lina Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1380335

1,926 views
1 citation

Review

Published on 02 Jan 2025

Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review

Huige Wang
Wenchao Yu
Tong Wang
Dianwei Fang
Zeyun Wang
Yuanhong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423717

5,903 views
1 citation

Original Research

Published on 24 Dec 2024

Mechanistic analysis of Tanshinone IIA’s regulation of the ATM/GADD45/ORC signaling pathway to reduce myocardial ischemia-reperfusion injury

Yiwei Sang
Jiangnan Du
Dilimulati Zulikala
Zhongqiang Sang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1510380

2,053 views
2 citations

Original Research

Published on 24 Dec 2024

Efficacy of Hongjing I granule, an herbal medicine, in patients with mild to moderate erectile dysfunction in a randomized controlled trial

Run-Nan Xu
Jun Guo
Chun-He Zhang
Qing Zhou
Qiang Gen
Fu Wang
Yu Zhao
Xin-Yun Luo
Yan-Feng Li
Yi-Jia Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1367812

3,979 views
1 citation

Original Research

Published on 24 Dec 2024

Emodin induced hepatic steatosis in BALb/c mice by modulating the gut microbiota composition and fatty acid metabolism

Xinhua Xia
Xueling He
Jinzhou Huang
Xuyang Hou
Chen Lin
Yaxiong Liu
Mei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516272

2,021 views
1 citation

Review

Published on 24 Dec 2024

Role of salvianolic acid B in the treatment of acute ischemic stroke: a systematic review and meta-analysis of animal models

Jiashan Wang
Pingping Su
Chenyu Wan
Yingqi Xu
Junyue Huang
Jianli Niu
Zhuqing Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1479765

3,547 views
10 citations

Review

Published on 24 Dec 2024

The protective effects of gastrodin on neurological disorders: an update and future perspectives

Zhouying Shi
Yali Zhang
Yuhua Xiao
Zhoujing Shi
Xiaotong Wei
Bin Wang
Yue Yuan
Ping Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494277

3,720 views
6 citations

Review

Published on 24 Dec 2024

Large language models facilitating modern molecular biology and novel drug development

Xiao-huan Liu
Zhen-hua Lu
Tao Wang
Fei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458739

6,493 views
10 citations

Original Research

Published on 24 Dec 2024

Carthamus tinctorius L. protects cerebral ischemia/reperfusion injury via arachidonic acid/p53-mediated apoptosis axis

Junren Chen
Liujun Wu
Xiaofang Xie
Cheng Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1504109

3,326 views
3 citations

Review

Published on 24 Dec 2024

Cutaneous adverse events associated with BRAF and MEK inhibitors: a systematic review and meta-analysis

Junhui Qian
Jinlong Wan
Qin Yao
Yin Chen
Tao Ling
Yuejuan Zhang
Zhihua Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1457226

3,550 views
1 citation

Original Research

Published on 24 Dec 2024

Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota

Yijia Zhong
Xiujuan Chang
Zihan Zhao
Lijun Zheng
Gaobo Kuang
Ping Li
Chenxuexuan Liu
Yuqin Fan
Zhixuan Liang
Ke Zhuang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1402465

4,510 views
10 citations

Original Research

Published on 23 Dec 2024

Safety assessment of deutetrabenazine: real-world adverse event analysis from the FAERS database

Yanping Shu
Yuanhe Wang
Jiaoying Liu
Lingyan Hu
Sichao Tong
Gang Wu
Xianlin Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1498215

3,229 views
1 citation

Review

Published on 23 Dec 2024

Platelets as crucial players in the dynamic interplay of inflammation, immunity, and cancer: unveiling new strategies for cancer prevention

Annalisa Contursi
Stefania Tacconelli
Sara Di Berardino
Alessandra De Michele
Paola Patrignani

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1520488

6,217 views
12 citations

Review

Published on 23 Dec 2024

Exosomal communication: a pivotal regulator of bone homeostasis and a potential therapeutic target

Qian-Yun Ye
Yan Cui
Hao-Yu Wang
Ling-Yu Li
Jian-Bing Chen
Xiao-Feng Zhu
Zhi-Jian Xue
Rong-Hua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516125

2,917 views
6 citations

Original Research

Published on 23 Dec 2024

Inhibition of the polyol pathway by Ducrosia anethifolia extract: plausible implications for diabetic retinopathy treatment

Saheem Ahmad
Mohammad Faizan Ali Ahmad
Saif Khan
Sultan Alouffi
Mahvish Khan
Mohd Wajid Ali Khan
Irfan Ahmad Ansari

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1513967

2,088 views
1 citation

Original Research

Published on 23 Dec 2024

Biocompatible nanoparticles self-assembled by PEGylated polyphosphoesters for combination of photodynamic therapy and hypoxia-activated chemotherapy against breast cancer

Fengyu Wang
Xiaojing Zou
Chunyang Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1529631

1,642 views

Review

Published on 23 Dec 2024

Comprehensive review on neprilysin (NEP) inhibitors: design, structure-activity relationships, and clinical applications

Xinyue Zhang
Chun Hu
Erkang Tian
Yanxin Shen
Wei Liu
Juan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1501407

6,487 views
3 citations

Original Research

Published on 23 Dec 2024

Zhili decoction ameliorates ulcerative colitis by modulating gut microbiota and related metabolite, and inhibiting the TLR4/NF-κB/NLRP3 pathway

Tianying Tan
Qin Chen
Ping Chen
Shuangshuang Li
Wenting Hu
Tao Yang
Yingtian Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1481273

3,097 views
1 citation

Original Research

Published on 23 Dec 2024

Chronic nicotine exposure induces molecular and transcriptomic endophenotypes associated with mood and anxiety disorders in a cerebral organoid neurodevelopmental model

Emma K. Proud
Mar Rodríguez-Ruiz
Dana M. Gummerson
Sebastian Vanin
Daniel B. Hardy
Walter J. Rushlow
Steven R. Laviolette

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1473213

2,831 views
4 citations

Original Research

Published on 23 Dec 2024

Medication non-adherence: reflecting on two decades since WHO adherence report and setting goals for the next twenty years

Przemyslaw Kardas
Bryan Bennett
Bijan Borah
Michel Burnier
Christopher Daly
Mickael Hiligsmann
Enrica Menditto
Andrew M. Peterson
Julia F. Slejko
Krisztina Tóth

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1444012

17,851 views
15 citations

Original Research

Published on 23 Dec 2024

Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments

Xuanlin Zhao
Fan Li
Ao Wen
Xiuxian Yu
Xinrui Xu
Chengyu Wan
Yu Cao
Guang Xin
Wen Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485915

2,584 views
2 citations

Original Research

Published on 23 Dec 2024

A supercritical oil extract of Schisandra chinensis seeds ameliorates Huntington’s disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects

Hyo-Sung Jo
Youn-Woo Lee
So-Ri Son
Dae Sik Jang
Tae Woo Kwon
Yujeong Ha
Sang-Kwan Moon
Min Soo Kim
Ik-Hyun Cho

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1471024

3,254 views

Review

Published on 20 Dec 2024

β-blockers and metabolic modulation: unraveling the complex interplay with glucose metabolism, inflammation and oxidative stress

Szymon Drygała
Michał Radzikowski
Mateusz Maciejczyk

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489657

8,999 views
13 citations

Original Research

Published on 20 Dec 2024

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

Kimberly J. Newsom
Bradley Hall
Katherine A. Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

5,191 views
3 citations

3,490 Publications

volumes

Integrated approach with UHPLC-Q-Exactive-tandem mass spectrometry, network analysis, and molecular docking to determine potential active compounds and mechanisms of Rhizoma Musae decoction in osteoarthritis treatment

Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review

Mechanistic analysis of Tanshinone IIA’s regulation of the ATM/GADD45/ORC signaling pathway to reduce myocardial ischemia-reperfusion injury

Efficacy of Hongjing I granule, an herbal medicine, in patients with mild to moderate erectile dysfunction in a randomized controlled trial

Emodin induced hepatic steatosis in BALb/c mice by modulating the gut microbiota composition and fatty acid metabolism

Role of salvianolic acid B in the treatment of acute ischemic stroke: a systematic review and meta-analysis of animal models

The protective effects of gastrodin on neurological disorders: an update and future perspectives

Large language models facilitating modern molecular biology and novel drug development

Carthamus tinctorius L. protects cerebral ischemia/reperfusion injury via arachidonic acid/p53-mediated apoptosis axis

Cutaneous adverse events associated with BRAF and MEK inhibitors: a systematic review and meta-analysis

Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota

Safety assessment of deutetrabenazine: real-world adverse event analysis from the FAERS database

Platelets as crucial players in the dynamic interplay of inflammation, immunity, and cancer: unveiling new strategies for cancer prevention

Exosomal communication: a pivotal regulator of bone homeostasis and a potential therapeutic target

Inhibition of the polyol pathway by Ducrosia anethifolia extract: plausible implications for diabetic retinopathy treatment

Biocompatible nanoparticles self-assembled by PEGylated polyphosphoesters for combination of photodynamic therapy and hypoxia-activated chemotherapy against breast cancer

Comprehensive review on neprilysin (NEP) inhibitors: design, structure-activity relationships, and clinical applications

Zhili decoction ameliorates ulcerative colitis by modulating gut microbiota and related metabolite, and inhibiting the TLR4/NF-κB/NLRP3 pathway

Chronic nicotine exposure induces molecular and transcriptomic endophenotypes associated with mood and anxiety disorders in a cerebral organoid neurodevelopmental model

Medication non-adherence: reflecting on two decades since WHO adherence report and setting goals for the next twenty years

Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments

A supercritical oil extract of Schisandra chinensis seeds ameliorates Huntington’s disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects

β-blockers and metabolic modulation: unraveling the complex interplay with glucose metabolism, inflammation and oxidative stress

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts