Frontiers in Pharmacology

Opinion

Published on 24 Feb 2022

Nanomedicines and Nanosimilars—Why a Robust Centralised Regulatory Framework Is Essential to Enhance Patient Safety

Michael P. Isles

Frontiers in Pharmacology

doi 10.3389/fphar.2021.787239

4,159 views
15 citations

Original Research

Published on 23 Feb 2022

Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice

Delma Veron
Pardeep K. Aggarwal
Qi Li
Gilbert Moeckel
Michael Kashgarian
Alda Tufro

Frontiers in Pharmacology

doi 10.3389/fphar.2021.788886

5,118 views
12 citations

Original Research

Published on 23 Feb 2022

Genetic Epidemiology of Medication Safety and Efficacy Related Variants in the Central Han Chinese Population With Whole Genome Sequencing

Junbo Tian
Jing Zhang
Zengguang Yang
Shuaisheng Feng
Shujuan Li
Shiqi Ren
Jianxiang Shi
Xinyue Hou
Xia Xue
Bei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.790832

4,010 views
4 citations

Original Research

Published on 23 Feb 2022

Construction of a Non-Mutually Exclusive Decision Tree for Medication Recommendation of Chronic Heart Failure

Yongyi Bai
Haishen Yao
Xuehan Jiang
Suyan Bian
Jinghui Zhou
Xingzhi Sun
Gang Hu
Lan Sun
Guotong Xie
Kunlun He

Frontiers in Pharmacology

doi 10.3389/fphar.2021.758573

4,573 views
6 citations

Original Research

Published on 23 Feb 2022

Efficient Synthesis of 2,3′-Spirobi (Indolin)-2′-Ones and Preliminary Evaluation of Their Damage to Mitochondria in HeLa Cells

Huajie Li
Zhenjie Yu
Haoyi Sun
Bo Liu
Xin Wang
Zhe Shao
Meiling Wang
Weilin Xie
Xingang Yao
Qingqiang Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.821518

2,930 views
6 citations

Original Research

Published on 23 Feb 2022

Ropivacaine Inhibits Lung Cancer Cell Malignancy Through Downregulation of Cellular Signaling Including HIF-1α In Vitro

Junmei Shen
Lina Han
Yongxian Xue
Chao Li
Huiqun Jia
Kangsheng Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.806954

2,841 views
12 citations

Original Research

Published on 22 Feb 2022

Use of Drugs With Risk of Heart Rate-Related Problems is Common in Norwegian Dementia Patients Treated With Acetylcholinesterase Inhibitors: A Prevalence Study Based on the Norwegian Prescription Database

Anne Sverdrup Efjestad
Hege Ihle-Hansen
Vidar Hjellvik
Knut Engedal
Hege Salvesen Blix

Frontiers in Pharmacology

doi 10.3389/fphar.2021.791578

3,194 views
1 citation

Original Research

Published on 22 Feb 2022

Effects of Irbesartan and Amlodipine Besylate Tablets on the Intestinal Microflora of Rats With Hypertensive Renal Damage

Jing Yu
Yan Ma
Xin He
Xiao Na Long
Jun Xu
Lei Wang
Zhi-Peng Feng
Hong-Ying Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.778072

4,337 views
4 citations

Original Research

Published on 22 Feb 2022

Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation

Danlei Li
Xiaoman Liu
Wenhu Pi
Yang Zhang
Lei Yu
Cheng Xu
Zhenzhu Sun
Jianjun Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.808480

22,584 views
171 citations

Review

Published on 21 Feb 2022

Bibliometric Analysis of Ferroptosis in Stroke From 2013 to 2021

Yuhua Chen
Tianlin Long
Quanhua Xu
Chi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.817364

10,742 views
23 citations

Original Research

Published on 16 Feb 2022

Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells

Xiaoyu Yan
Rui Tian
Jicheng Sun
Yuanxin Zhao
Buhan Liu
Jing Su
Minghua Li
Wei Sun
Xuesong Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.788667

5,521 views
18 citations

Original Research

Published on 15 Feb 2022

Identification of lncRNA Signature of Tumor-Infiltrating T Lymphocytes With Potential Implications for Prognosis and Chemotherapy of Head and Neck Squamous Cell Carcinoma

Liping Wang
Gui Yang
Guohong Liu
Yunbao Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2021.795205

5,484 views
13 citations

Review

Published on 15 Feb 2022

Progress in the Mechanism of Autophagy and Traditional Chinese Medicine Herb Involved in Dementia

Pengyu Tao
Jing Ji
Simeng Gu
Qian Wang
Yuzhen Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.825330

4,762 views
15 citations

Original Research

Published on 14 Feb 2022

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides

Qiaoli Shi
Qixin Wang
Jiayun Chen
Fei Xia
Chong Qiu
Min Li
Minghong Zhao
Qian Zhang
Piao Luo
Tianming Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.822154

5,495 views
20 citations

Original Research

Published on 14 Feb 2022

Tricyclic Antidepressant Structure-Related Alterations in Calcium-Dependent Inhibition and Open-Channel Block of NMDA Receptors

Yulia D. Stepanenko
Dmitry A. Sibarov
Natalia N. Shestakova
Sergei M. Antonov

Frontiers in Pharmacology

doi 10.3389/fphar.2021.815368

5,187 views
15 citations

Review

Published on 14 Feb 2022

Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution?

Gerald Zirintunda
Savino Biryomumaisho
Keneth Iceland Kasozi
Gaber El-Saber Batiha
John Kateregga
Patrick Vudriko
Sarah Nalule
Deogracious Olila
Mariam Kajoba
Kevin Matama

Frontiers in Pharmacology

doi 10.3389/fphar.2021.774896

32,964 views
25 citations

Original Research

Published on 14 Feb 2022

SPHK Inhibitors and Zoledronic Acid Suppress Osteoclastogenesis and Wear Particle-Induced Osteolysis

Minghui Gu
Baiqi Pan
Weishen Chen
Hai Xu
Xiaoyu Wu
Xuantao Hu
Linli Zheng
Yongyu Ye
Qing Meng
Guoyan Xian

Frontiers in Pharmacology

doi 10.3389/fphar.2021.794429

4,868 views
7 citations

Original Research

Published on 11 Feb 2022

Derivation of a Human In Vivo Benchmark Dose for Bisphenol A from ToxCast In Vitro Concentration Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitro to In Vivo Extrapolation

George Loizou
Kevin McNally
Alicia Paini
Alex Hogg

Frontiers in Pharmacology

doi 10.3389/fphar.2021.754408

5,669 views
8 citations

Review

Published on 11 Feb 2022

Heptamethine Cyanine–Based Application for Cancer Theranostics

Lei Zhang
Hang Jia
Xuqian Liu
Yaxin Zou
Jiayi Sun
Mengyu Liu
Shuangshuang Jia
Nan Liu
Yanzhang Li
Qun Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.764654

9,087 views
28 citations

Original Research

Published on 11 Feb 2022

The Neuroprotective Effects of Coreopsis tinctoria and Its Mechanism: Interpretation of Network Pharmacological and Experimental Data

Pei Ma
Rong Zhang
Lijia Xu
Haibo Liu
Peigen Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.791288

4,807 views
6 citations

Review

Published on 10 Feb 2022

Pharmacogenetics in Primary Headache Disorders

Irina I. Belyaeva
Anna G. Subbotina
Ivan I. Eremenko
Vadim V. Tarasov
Vladimir N. Chubarev
Helgi B. Schiöth
Jessica Mwinyi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.820214

10,767 views
19 citations

Original Research

Published on 10 Feb 2022

Qingda Granule Attenuates Angiotensin II-Induced Renal Apoptosis and Activation of the p53 Pathway

Linzi Long
Xiuli Zhang
Ying Wen
Jiapeng Li
Lihui Wei
Ying Cheng
Huixin Liu
Jianfeng Chu
Yi Fang
Qiurong Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2021.770863

4,277 views
21 citations

Original Research

Published on 10 Feb 2022

Cordyceps cicadae Ameliorates Renal Hypertensive Injury and Fibrosis Through the Regulation of SIRT1-Mediated Autophagy

Yuzi Cai
Zhendong Feng
Qi Jia
Jing Guo
Pingna Zhang
Qihan Zhao
Yao Xian Wang
Yu Ning Liu
Wei Jing Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.801094

8,059 views
32 citations

Original Research

Published on 09 Feb 2022

Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions

Li Peng
Lijuan Wen
Jie Zhang
Xiaotong Zhang
Qin Wei
Jing Guo
Jinhao Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.639580

7,151 views
10 citations

4,137 Publications

volumes

Nanomedicines and Nanosimilars—Why a Robust Centralised Regulatory Framework Is Essential to Enhance Patient Safety

Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice

Genetic Epidemiology of Medication Safety and Efficacy Related Variants in the Central Han Chinese Population With Whole Genome Sequencing

Construction of a Non-Mutually Exclusive Decision Tree for Medication Recommendation of Chronic Heart Failure

Efficient Synthesis of 2,3′-Spirobi (Indolin)-2′-Ones and Preliminary Evaluation of Their Damage to Mitochondria in HeLa Cells

Ropivacaine Inhibits Lung Cancer Cell Malignancy Through Downregulation of Cellular Signaling Including HIF-1α In Vitro

Use of Drugs With Risk of Heart Rate-Related Problems is Common in Norwegian Dementia Patients Treated With Acetylcholinesterase Inhibitors: A Prevalence Study Based on the Norwegian Prescription Database

Effects of Irbesartan and Amlodipine Besylate Tablets on the Intestinal Microflora of Rats With Hypertensive Renal Damage

Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation

Bibliometric Analysis of Ferroptosis in Stroke From 2013 to 2021

Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells

Identification of lncRNA Signature of Tumor-Infiltrating T Lymphocytes With Potential Implications for Prognosis and Chemotherapy of Head and Neck Squamous Cell Carcinoma

Progress in the Mechanism of Autophagy and Traditional Chinese Medicine Herb Involved in Dementia

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides

Tricyclic Antidepressant Structure-Related Alterations in Calcium-Dependent Inhibition and Open-Channel Block of NMDA Receptors

Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution?

SPHK Inhibitors and Zoledronic Acid Suppress Osteoclastogenesis and Wear Particle-Induced Osteolysis

Derivation of a Human In Vivo Benchmark Dose for Bisphenol A from ToxCast In Vitro Concentration Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitro to In Vivo Extrapolation

Heptamethine Cyanine–Based Application for Cancer Theranostics

The Neuroprotective Effects of Coreopsis tinctoria and Its Mechanism: Interpretation of Network Pharmacological and Experimental Data

Pharmacogenetics in Primary Headache Disorders

Qingda Granule Attenuates Angiotensin II-Induced Renal Apoptosis and Activation of the p53 Pathway

Cordyceps cicadae Ameliorates Renal Hypertensive Injury and Fibrosis Through the Regulation of SIRT1-Mediated Autophagy

Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions