volumes

Volume 16 - 2025

Hypothesis and Theory

Published on 12 Jan 2026

X-inactive specific transcript (XIST) can determine sex differences in cardiovascular drug responses: focus on RNA therapeutics

Timur O. Yarovinsky
Vinod S. Ramgolam
Iva R. Knezevic
Nina S. Stachenfeld
Jeffrey R. Bender

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716863

957 views

Original Research

Published on 12 Jan 2026

Partially hydrolyzed formula with high sn-2 palmitic acid on eosinophils and outcomes in preterm infants: PRIOR secondary analysis

Jialu Zhuang
Ye Liu
Qiongyu Liu
Jiaan Wang
Songlin Liu
Jing Wu
Yanqing Shen
Xuemin Wang
Hui Zhang
Li Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1724281

688 views

Original Research

Published on 12 Jan 2026

Network pharmacology-based identification of potential drug targets and bioactive compounds in Lycii Fructus (Gouqizi) for the therapeutics of Parkinson’s disease

Sufana Al Hashmi
Rana Adnan Tahir
Sheikh Arslan Sehgal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714071

1,601 views
1 citation

Original Research

Published on 12 Jan 2026

Characterization of the biodistribution profile of a human Dialyzable Leukocyte Extract (hDLE) by in vivo fluorescence imaging: a strategy to infer the ADME profile of complex multipeptide drugs

Ana Fragozo
Ismael Trejo-Martínez
Kuauhtémok Domínguez-Bernal
Luis Valencia-Flores
Zaira Macias-Palacios
Lenin Pavón
Armando Pérez-Torres
Francisco A. Aguilar-Alonso
Said Vázquez-Leyva
Luis Vallejo-Castillo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701647

998 views

Original Research

Published on 12 Jan 2026

Association of medication regimen complexity index with ADRs in HIV/AIDS patients: a retrospective cohort study

Ji Sun
Hui Qi
Jingmeng Huang
Ying Wang
Yu Xiang
Gefei He
Shiqiong Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721289

654 views

Editorial

Published on 12 Jan 2026

Editorial: Genomic discoveries and pharmaceutical development in urologic tumors - volume II

Wenjia Li
Jialin Meng
Huan Yang
Tao Zhang
Lei Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1743378

537 views

Original Research

Published on 12 Jan 2026

γ-Mangostin attenuates osteoclastogenesis and bone resorption by suppressing the PI3K/AKT/NF-κB pathway

Jian Wei
Jiayue Xie
Zhiyang He
Xiaofeng Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1742401

655 views

Original Research

Published on 12 Jan 2026

Psychotropic medication use and risks of kidney injury and fall-related events: a propensity score–matched cohort study

Yu-Hsien Wu
Shang-Feng Tsai
Shiau-Shian Huang
Po-Hsun Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1690792

879 views

Review

Published on 12 Jan 2026

Genome-wide association studies and traditional Chinese medicine in hyperuricemia: current evidence and mechanistic insights

Le Yang
Jing Liu
Shengping Luo
Yihui Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1647264

1,043 views

Original Research

Published on 09 Jan 2026

Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data

Tingting Yang
Xiaoxiao Wu
Xueliang Yi
Chunlin Xiang
Yinping Yang
Chen Yang
Xiaoxia Zheng
Yuhong Han
Yiping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1737359

1,149 views

Original Research

Published on 09 Jan 2026

Dual therapy with allicin and metformin provides superior cardioprotection against doxorubicin-induced cardiotoxicity in rats compared to monotherapy

Mohammed Mojamel
Hassan Al-Mahbashi
Afif Al-Nabehi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725943

848 views

Original Research

Published on 09 Jan 2026

Exploring the therapeutic potential of baicalin against MCF-7 breast cancer cells: biochemical, in vitro, and computational perspectives

Adil Ali
Tarun Kumar Upadhyay
Lamya Ahmed Al-Keridis
Mohammad Y. Alshahrani
Nawaf Alshamamri
Mohd Saeed

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698631

1,980 views
2 citations

Original Research

Published on 09 Jan 2026

Liuwei Dihuang pills ameliorate renal injury in experimental type 2 diabetes mellitus rat by regulating host-gut microbiota interaction

Han Jiang
Xiao-wan Hu
Xu Deng
Xian-jie Huang
Yu-lin Chen
Yi-fan Yang
Yan Du
Shuai Ji
Dao-quan Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715600

1,253 views

Original Research

Published on 09 Jan 2026

Lack of formal regulatory definitions of off-label medication use in children: an analysis using agency inquiry and text mining

Christina Gade
Ulrik Lausten-Thomsen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1750718

634 views

Brief Research Report

Published on 09 Jan 2026

Subclavian artery stenosis in hemodialysis patients: a case series and review of the literature

Wenshen Pu
Jingjie Yang
Qiquan Lai
Yu Zhou
Bo Tu
Bingjie Wang
Ziming Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689306

714 views

Systematic Review

Published on 09 Jan 2026

Rodent models of genetic epilepsy and its association with neurocognitive impairment- a systematic review

Renee Yan Ni Foo
Ian Juin Liang Chiew
Alina Arulsamy
Vanessa Lin Lin Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1659569

882 views

Opinion

Published on 09 Jan 2026

Integrating traditional and herbal medicine into heatwave resilience and care

M. L. Manoj
Kranthi Kiran Akula
Harsha Hegde
Subarna Roy

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712917

885 views

Editorial

Published on 09 Jan 2026

Editorial: Metabolic dysfunction-associated fatty liver disease (MAFLD): innovative management strategies using herbal medicines

Yunhui Chen
Yujie Liu
Qing Zhang
Wei Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1742956

634 views

Review

Published on 09 Jan 2026

Unveiling abietic Acid’s therapeutic potential: a narrative review on structure-activity relationship, pharmacological properties, pharmacokinetics, and toxicological considerations

Wanqing Ren
Tongzheng Liu
Jianlin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1738572

1,224 views

Original Research

Published on 09 Jan 2026

Levocarnitine improves cardiac energy metabolic remodeling in myocarditis mice

Shutong Yang
Xiaoou Li
Zhenpeng Lu
Xiang Xu
Zuzhen Guo
Bing He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706936

810 views

Volume 17 - 2026

Systematic Review

Published on 12 Jan 2026

Melatonin supplementation reduces delirium incidence in critically ill patients: a systematic review and meta-analysis

Xiaoyu Wu
Panxin Hu
Haopeng Wu
Kai Zhang
Jianzhi Ying

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1728873

874 views

Original Research

Accepted on 09 Jan 2026

Chrysin, a Natural Kv7 Potassium Channel Opener, Alleviates Chronic Pain by Restoring M-current Activity in Sensory Neurons

Muhammed Yusuf
Ayfer Busra Benkli

Frontiers in Pharmacology

1,198 views

Review

Accepted on 09 Jan 2026

Genome agnostic, multi-level non-oncogene addiction-based systems pharmacology for rescuing metastatic relapsed/refractory neoplasias

Dennis Christoph Harrer
Florian Lüke
Tobias Pukrop
Lina Ghibelli
Albrecht Reichle
Daniel Heudobler

Frontiers in Pharmacology

207 views

Original Research

Accepted on 09 Jan 2026

18-Glycyrrhetinic Acid Suppresses Glioblastoma by Regulating p38 signaling pathway: An Integrative Approach Combining Network Analysis, Transcriptomics, and Experimental Validation

Xuanzhi Luo
Mujin Li
Xue Wang
Yuan Zeng
Ya-Lei Wang
Tiantian Peng
Cuiyan Ma
Qian Hua

Frontiers in Pharmacology

195 views