Frontiers in Pharmacology

Original Research

Published on 21 Jan 2025

Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway

Yan Ye
Xiaopeng Huang
Xueying Li
Fei Gao
Wenzhen Zhong
Anqi Tang
Liangbin Zhao
Dengpiao Xie
Naijing Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453668

4,423 views
1 citation

Original Research

Published on 20 Jan 2025

Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells

Xixi Hou
Longfei Mao
Huibin Zhang
Lan Wang
Baoyu He
Jingjing Guo
Jianji Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1509520

3,934 views
7 citations

Original Research

Published on 20 Jan 2025

Towards implementing new payment models for the reimbursement of high-cost, curative therapies in Europe: insights from semi-structured interviews

Thomas Desmet
Sissel Michelsen
Elena Van den Brande
Walter Van Dyck
Steven Simoens
Isabelle Huys

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1397531

3,393 views
2 citations

Original Research

Published on 20 Jan 2025

α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach

Aimin Cai
Dingchao Shen
Qiushuang Xiong
Jie Ding
Yang Ding
Xinlu Lin
Lijia Chen
Qing Yao
Guangyong Lin
Ruijie Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1463673

2,914 views
2 citations

Original Research

Published on 20 Jan 2025

4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies

Ashanul Haque
Khalaf M. Alenezi
Mohd. Saeed Maulana Abdul Rasheed
Md. Ataur Rahman
Saleha Anwar
Shahzaib Ahamad
Dinesh Gupta

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1517504

7,240 views
2 citations

Original Research

Published on 20 Jan 2025

Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway

Ju Huang
Jing Li
Zhijun Geng
Lixia Yin
Minzhu Niu
Qingqing Li
Xinyue Liu
Xinke Cheng
Xiaofeng Zhang
Xue Song

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496068

3,380 views
3 citations

Original Research

Published on 20 Jan 2025

Enhanced antitumor efficacy through sustained release of 5-fluorouracil from poly(trimethylene carbonate) membranes

Zongheng Wang
Zhipeng Hou
Shuguang Zhang
Shuangyi Ren
Liqun Yang
Qianshi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1536764

1,629 views

Original Research

Published on 20 Jan 2025

Nicotine’s impact on platelet function: insights into hemostasis mechanisms

Xiayu Wu
Yongjun Liu
Changhao Zou
Fuqin He
Fang Guo
Sijia Liu
Yi Fan
Xuedong Zhu
Qianyi Zhou
Dan Shu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1512142

3,604 views
4 citations

Mini Review

Published on 20 Jan 2025

The potential role of nanobodies in asthma therapy

Baraa Khalid Salah Al-Sheakly
Fatemeh Saheb Sharif-Askari
Narjes Saheb Sharif-Askari
Jennifer E. Hundt
Rabih Halwani

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1510806

3,453 views
1 citation

Review

Published on 20 Jan 2025

A review of Psoralea corylifolia L.: a valuable plant with profound biological significance

Anni Yang
Lingping Kong
Zhibo You
Xinyu Li
Jian Guan
Fengjin Li
Lingyun Zhong
Hai Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1521040

8,344 views
10 citations

Review

Published on 20 Jan 2025

Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus

Xu He
Wei Zhao
PeiHang Li
YinJiang Zhang
GuoHua Li
HongYu Su
BiNan Lu
ZongRan Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1483792

5,795 views
6 citations

Clinical Trial

Published on 17 Jan 2025

Effects of oral Lcarnitine supplementation on liver enzymes in pediatric acute lymphoblastic leukemia patients in the maintenance phase of treatment: a randomized clinical trial study

Aziz Eghbali
Aygin Eghbali
Neda Ashayeri
Fatemeh Fadayi
Kazem Ghaffari
Ali Ghasemi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1507996

2,298 views
3 citations

Original Research

Published on 17 Jan 2025

Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms

Monika Jürgenson
Keerthana Chithanathan
Aivar Orav
Külli Jaako
Janeli Viil
Mithu Guha
Kalev Kask
Alexander Zharkovsky

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505729

4,260 views

Original Research

Published on 17 Jan 2025

Comparative study on the bioavailability and bioequivalence of rifapentine capsules in humans

Ying Qi
Pengfei Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1463575

2,905 views
1 citation

Systematic Review

Published on 17 Jan 2025

Efficacy and safety of tripterygium glycosides combined with ACEI/ARB on diabetic nephropathy: a meta-analysis

Zhuan’E. Yao
Pengbo Wang
Qinjuan Fu
Qiong Song
Haojian Xu
Peng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1493590

2,482 views
2 citations

Original Research

Published on 17 Jan 2025

VASN knockout induces myocardial fibrosis in mice by downregulating non-collagen fibers and promoting inflammation

Junming Sun
Siwei Yin
Qiurui Li
Jun Zhang
Xiaoping Guo
Na Yu
Bing Hu
Yiqiang Ouyang
Qiaojuan Huang
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500617

2,225 views
2 citations

Review

Published on 17 Jan 2025

Plant protein-derived anti-breast cancer peptides: sources, therapeutic approaches, mechanisms, and nanoparticle design

Deju Zhang
Ying Yuan
Qingdong Zeng
Juan Xiong
Yiming Gan
Kai Jiang
Ni Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1468977

4,266 views
20 citations

Original Research

Published on 16 Jan 2025

Protective effect and mechanism of Sufentanil on acute lung injury in septic mice

Hongqiao Hou
Bowen Jiang
Aiqing Zhu
Junjun Hou
Zhe Qu
Ruping Liu
Aiqun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1514602

2,504 views

Original Research

Published on 16 Jan 2025

Walnut oil prevents hyperlipidemia induced by high-fat diet and regulates intestinal flora and liver metabolism

Rui Yang
Dan Chen
Yanling Chen
Yage Ma
Chaoyin Chen
Shenglan Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431649

2,472 views

Brief Research Report

Published on 16 Jan 2025

Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses

Yu-Wei Lin
Anna Largajolli
A. Yin Edwards
S. Y. Amy Cheung
Kashyap Patel
Stefanie Hennig

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1487062

2,664 views
2 citations

Review

Published on 15 Jan 2025

A review of the Bovis Calculus’s intervention mechanism and clinical application in ischemic stroke

Ke Xu
Bowen Deng
Tongtong Jia
Mihong Ren
Hai Chen
Jing Zhang
Jinlin Guo
Yong Li
Jian Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1510779

4,337 views
3 citations

Original Research

Published on 15 Jan 2025

Large variability in the alkaloid content of Corydalis yanhusuo dietary supplements

Paula B. Luis
Claus Schneider

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1518750

11,727 views

Original Research

Published on 15 Jan 2025

Parishin B blocking TRIB3-AKT1 interaction inhibits breast cancer lung metastasis

Xiongtao Cheng
Jianguo Sun
Shouhong Chen
Nan Wang
Weijing Tang
Zijian Xia
Yuhong Shu
Shouhong Gao
Zhipeng Wang
Xinxia Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1517708

3,018 views
6 citations

Original Research

Published on 15 Jan 2025

Drug-induced heart failure: a real-world pharmacovigilance study using the FDA adverse event reporting system database

Youqi Huang
Xiaowen Chen
Mingyu Chen
Yuze Lin
Bingqi Chen
Hongjin Gao
Min Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1523136

4,098 views
1 citation

3,490 Publications

volumes

Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway

Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells

Towards implementing new payment models for the reimbursement of high-cost, curative therapies in Europe: insights from semi-structured interviews

α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach

4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies

Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway

Enhanced antitumor efficacy through sustained release of 5-fluorouracil from poly(trimethylene carbonate) membranes

Nicotine’s impact on platelet function: insights into hemostasis mechanisms

The potential role of nanobodies in asthma therapy

A review of Psoralea corylifolia L.: a valuable plant with profound biological significance

Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus

Effects of oral Lcarnitine supplementation on liver enzymes in pediatric acute lymphoblastic leukemia patients in the maintenance phase of treatment: a randomized clinical trial study

Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms

Comparative study on the bioavailability and bioequivalence of rifapentine capsules in humans

Efficacy and safety of tripterygium glycosides combined with ACEI/ARB on diabetic nephropathy: a meta-analysis

VASN knockout induces myocardial fibrosis in mice by downregulating non-collagen fibers and promoting inflammation

Plant protein-derived anti-breast cancer peptides: sources, therapeutic approaches, mechanisms, and nanoparticle design

Protective effect and mechanism of Sufentanil on acute lung injury in septic mice

Walnut oil prevents hyperlipidemia induced by high-fat diet and regulates intestinal flora and liver metabolism

Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses

A review of the Bovis Calculus’s intervention mechanism and clinical application in ischemic stroke

Large variability in the alkaloid content of Corydalis yanhusuo dietary supplements

Parishin B blocking TRIB3-AKT1 interaction inhibits breast cancer lung metastasis

Drug-induced heart failure: a real-world pharmacovigilance study using the FDA adverse event reporting system database