Frontiers in Pharmacology

Original Research

Published on 12 Jan 2023

Gel formulated with Bryophyllum pinnatum leaf extract promotes skin wound healing in vivo by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals

Edilane Rodrigues Dantas Araújo
Jacinthia Beatriz Xavier-Santos
Valéria Costa da Silva
Juliana Bessa Figueiredo de Lima
Jade Schlamb
Matheus de Freitas Fernandes-Pedrosa
Arnóbio Antônio da Silva Júnior
Raimundo Fernandes de Araújo Júnior
Thirumurugan Rathinasabapathy
Marvin Moncada

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1104705

17,880 views
15 citations

Original Research

Published on 12 Jan 2023

Factors associated with the uptake of biosimilars for breast cancer treatment from the perspectives of physicians and patients-Evidence from China

Qiyou Wu
Zhiwei Lian
Xin Wang
Hanchao Cheng
Jing Sun
Hui Yu
Gong Zhang
Fan Wu
Jian Liu
Chuanben Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1044798

3,427 views
7 citations

Original Research

Published on 12 Jan 2023

Adherence and treatment patterns of disease-specific drugs among patients with pulmonary arterial hypertension: A nationwide, new-user cohort study

Cheng-Yu Tsai
Chuan-Wei Shen
Hsuan-Lin Lai
Chung-Yu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1030693

5,914 views
9 citations

Original Research

Published on 12 Jan 2023

Green synthesis of hyaluronic acid coated, thiolated chitosan nanoparticles for CD44 targeted delivery and sustained release of Cisplatin in cervical carcinoma

Kousain Kousar
Faiza Naseer
Maisa S. Abduh
Salik Kakar
Rabia Gul
Sadia Anjum
Tahir Ahmad

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1073004

8,362 views
60 citations

Correction

Published on 12 Jan 2023

Corrigendum: Wuzi Yanzong pill—Based on network pharmacology and In Vivo evidence—Protects against spermatogenesis disorder via the regulation of the apoptosis pathway

Wang-qiang Chen
Cai-fei Ding
Jia Yu
Chen-ye Wang
Ling-yi Wan
Hui-min Hu
Jian-xiong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1129448

1,931 views
1 citation

Review

Published on 12 Jan 2023

Protective effect of natural products in the metabolic-associated kidney diseases via regulating mitochondrial dysfunction

Peng Liu
Yao Chen
Jing Xiao
Wenhui Zhu
Xiaoming Yan
Ming Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1093397

4,425 views
14 citations

Original Research

Published on 12 Jan 2023

Research trends and hotspots of neurodegenerative diseases employing network pharmacology: A bibliometric analysis

Jie Zhu
Qingchun Liang
Siyi He
Chen Wang
Xiafei Lin
Duozhi Wu
Guanwen Lin
Zhihua Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1109400

7,287 views
10 citations

Correction

Published on 12 Jan 2023

Corrigendum: R-carvedilol, a potential new therapy for Alzheimer’s disease

Jinjing Yao
S. R. Wayne Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1125890

1,674 views

Original Research

Published on 12 Jan 2023

Piper sarmentosum Roxb. methanolic extract prevents stress-induced gastric ulcer by modulating oxidative stress and inflammation

Muhamad Nurul Akmal
Ibrahim Abdel Aziz
Mohd Fahami Nur Azlina

Frontiers in Pharmacology

doi 10.3389/fphar.2022.971443

4,296 views
15 citations

Original Research

Published on 12 Jan 2023

Association between fibrinogen/albumin ratio and arterial stiffness in patients with type 2 diabetes: A cross-sectional study

Chun-mei Chen
Chun-feng Lu
Wang-shu Liu
Zhen-hua Gong
Xue-qin Wang
Feng Xu
Jian-feng Ji
Xing-xing Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1120043

2,730 views
12 citations

Original Research

Published on 12 Jan 2023

Identification of a novel P2X7 antagonist using structure-based virtual screening

Gaia Pasqualetto
Marika Zuanon
Andrea Brancale
Mark T. Young

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1094607

4,394 views
5 citations

Review

Published on 12 Jan 2023

Recent advances of tanshinone in regulating autophagy for medicinal research

Sha Wu
Kui Zhao
Jie Wang
Nannan Liu
Kaidi Nie
Luming Qi
Lina Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1059360

6,435 views
27 citations

Original Research

Published on 12 Jan 2023

Fast cycling of intermittent hypoxia in a physiomimetic 3D environment: A novel tool for the study of the parenchymal effects of sleep apnea

Alicia Jurado
Anna Ulldemolins
Helena Lluís
Xavier Gasull
Núria Gavara
Raimon Sunyer
Jorge Otero
David Gozal
Isaac Almendros
Ramon Farré

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1081345

2,910 views
2 citations

Review

Published on 12 Jan 2023

Molecular profiling of urinary extracellular vesicles in chronic kidney disease and renal fibrosis

Melanie Tepus
Elisa Tonoli
Elisabetta A. M. Verderio

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1041327

6,450 views
12 citations

Original Research

Published on 12 Jan 2023

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

Robin Michelet
Davide Bindellini
Johanna Melin
Uta Neumann
Oliver Blankenstein
Wilhelm Huisinga
Trevor N. Johnson
Martin J. Whitaker
Richard Ross
Charlotte Kloft

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1090554

3,461 views
4 citations

Editorial

Published on 11 Jan 2023

Editorial: Dietary polyphenols, gut microbiota, and human health

Lei Xu
Xin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1131074

2,831 views
5 citations

Original Research

Published on 11 Jan 2023

DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress

Hui Zhang
Laifa Wang
Yongping Yang
Chuanhai Cai
Xueqin Wang
Ling Deng
Binsheng He
Wenhu Zhou
Yanhui Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2022.987293

8,378 views
65 citations

Original Research

Published on 11 Jan 2023

Alkaloid from Alstonia yunnanensis diels root against gastrointestinal cancer: Acetoxytabernosine inhibits apoptosis in hepatocellular carcinoma cells

Qi Lai
Chun-Ju Yang
Qi zhang
Min Zhuang
Yan-Hua Ma
Cheng-Yuan Lin
Guang-Zhi Zeng
Jun-Lin Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1085309

4,019 views
10 citations

Original Research

Published on 11 Jan 2023

Natural product manoalide promotes EGFR-TKI sensitivity of lung cancer cells by KRAS-ERK pathway and mitochondrial Ca2+ overload-induced ferroptosis

Yinyun Ni
Jiaye Liu
Lingyan Zeng
Ying Yang
Lei Liu
Menglin Yao
Li Chai
Lu Zhang
Yi Li
Li Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1109822

11,607 views
26 citations

Editorial

Published on 11 Jan 2023

Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, Volume II

Yanzhu Zhu
Fatma M. El-Demerdash
Xu Yang
Alex Boye
Michel Mansur Machado
Xinwei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1107327

1,594 views

Correction

Published on 11 Jan 2023

Corrigendum: Formulation and development of transferrin targeted solid lipid nanoparticles for breast cancer therapy

Geeta S. Bhagwat
Rajani B. Athawale
Rajeev P. Gude
Shadab Md
Nabil A. Alhakamy
Usama A. Fahmy
Prashant Kesharwani

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1123542

1,545 views

Original Research

Published on 11 Jan 2023

A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

Kakeru Sato
Tatsuya Seki
Asuka Mizutani
Yuka Muranaka
Shiho Hirota
Kodai Nishi
Kana Yamazaki
Ryuichi Nishii
Takeo Nakanishi
Ikumi Tamai

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1069321

3,677 views
4 citations

Original Research

Published on 11 Jan 2023

Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal

Wan Kong
Shanqing Huang
Zikai Chen
Xiaolin Li
Shujing Liu
Zi Zhang
Ye Yang
Zhanzhang Wang
Xiuqing Zhu
Xiaojia Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1111758

3,488 views
2 citations

Original Research

Published on 11 Jan 2023

Integrated untargeted and targeted metabolomics to reveal therapeutic effect and mechanism of Alpiniae oxyphyllae fructus on Alzheimer’s disease in APP/PS1 mice

Shengnan Zhou
Liwei Liu
Yuanyuan Zhang
Zhibo Zhang
Hanbing Li
Feng Fan
Jiuming He
Jian Kang
Lihua Zuo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1104954

6,352 views
9 citations

5,553 Publications

volumes

Gel formulated with Bryophyllum pinnatum leaf extract promotes skin wound healing in vivo by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals

Factors associated with the uptake of biosimilars for breast cancer treatment from the perspectives of physicians and patients-Evidence from China

Adherence and treatment patterns of disease-specific drugs among patients with pulmonary arterial hypertension: A nationwide, new-user cohort study

Green synthesis of hyaluronic acid coated, thiolated chitosan nanoparticles for CD44 targeted delivery and sustained release of Cisplatin in cervical carcinoma

Corrigendum: Wuzi Yanzong pill—Based on network pharmacology and In Vivo evidence—Protects against spermatogenesis disorder via the regulation of the apoptosis pathway

Protective effect of natural products in the metabolic-associated kidney diseases via regulating mitochondrial dysfunction

Research trends and hotspots of neurodegenerative diseases employing network pharmacology: A bibliometric analysis

Corrigendum: R-carvedilol, a potential new therapy for Alzheimer’s disease

Piper sarmentosum Roxb. methanolic extract prevents stress-induced gastric ulcer by modulating oxidative stress and inflammation

Association between fibrinogen/albumin ratio and arterial stiffness in patients with type 2 diabetes: A cross-sectional study

Identification of a novel P2X7 antagonist using structure-based virtual screening

Recent advances of tanshinone in regulating autophagy for medicinal research

Fast cycling of intermittent hypoxia in a physiomimetic 3D environment: A novel tool for the study of the parenchymal effects of sleep apnea

Molecular profiling of urinary extracellular vesicles in chronic kidney disease and renal fibrosis

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

Editorial: Dietary polyphenols, gut microbiota, and human health

DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress

Alkaloid from Alstonia yunnanensis diels root against gastrointestinal cancer: Acetoxytabernosine inhibits apoptosis in hepatocellular carcinoma cells

Natural product manoalide promotes EGFR-TKI sensitivity of lung cancer cells by KRAS-ERK pathway and mitochondrial Ca2+ overload-induced ferroptosis

Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, Volume II

Corrigendum: Formulation and development of transferrin targeted solid lipid nanoparticles for breast cancer therapy

A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal

Integrated untargeted and targeted metabolomics to reveal therapeutic effect and mechanism of Alpiniae oxyphyllae fructus on Alzheimer’s disease in APP/PS1 mice