Frontiers in Pharmacology

Original Research

Published on 05 Jan 2026

Cost-effectiveness analysis of inavolisib combined with palbociclib plus fulvestrant in PIK3CA-mutated HR+/Her2− advanced breast cancer in China

Weiwei Huang
Cijuan Li
Yuanqing Huang
Chang Wang
Yingxin Zhang
Yingtao Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1742507

1,024 views

Systematic Review

Published on 05 Jan 2026

Comparative efficacy and safety of imrecoxib versus celecoxib: a systematic review and meta-analysis

Xian Zeng
Lilin Dai
Zude Li
Xiaomin Dong
Zengzhen Liao
Liji Chen
Yuan Tan
Wei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707079

905 views

Original Research

Published on 05 Jan 2026

Maternal influenza vaccination during pregnancy and the risk of adverse pregnancy and birth outcomes

Vanina Tchuente
Odile Sheehy
Gina Muckle
Mark Walker
William D. Fraser
Anick Bérard

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691111

906 views

Original Research

Published on 05 Jan 2026

Antibiotic use for respiratory tract infections in nursing homes: a multicentre cross-sectional study

Carl Llor
Rosa Morros
Jesús Mateos-Nozal
Carlota Manuela Zárate Sáez
María N. Vaquero Pinto
Consuelo Rodríguez Jiménez
Carmen Sáez Bejar
Rosa Magallón-Botaya
Priscila Matovelle
Alicia Navarro Sanmartín

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721689

845 views

Review

Published on 05 Jan 2026

Osteoarthritis: multitissue pathology, molecular mechanisms, clinical management, and emerging precision and regenerative therapies

Lina Qiu
Ahmad Alhaskawi
Safwat Adel Abdo Moqbel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697192

1,456 views
1 citation

Systematic Review

Published on 05 Jan 2026

Different traditional Chinese medicine injections combined with conventional therapy for sepsis-induced myocardial dysfunction: a systematic review and network meta-analysis

Wenjie Deng
Xiaolei Fang
Po Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688113

821 views

Original Research

Published on 05 Jan 2026

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for bimekizumab

Zhuomiao Lin
Xihui Yu
Meiqing Yang
Jialan Xu
Jiahong Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714173

1,406 views

Review

Published on 05 Jan 2026

Molecular insights into NLRP3 inflammasome and miRNA modulation in oral cancer

Deborah Mannino
Morena D’Ariano
Ivana Bello
Irene Paterniti
Giovanna Casili
Elisabetta Panza

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713259

1,066 views

Systematic Review

Published on 05 Jan 2026

The anti-osteoporotic effect of puerarin on the femoral bone in rat models of osteoporosis: a systematic review and meta-analysis

Zhaoxi Yang
Rui Tang
Yulin Ma
Wenlong Luo
Yimei Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712682

1,066 views

Original Research

Published on 05 Jan 2026

Astaxanthin activates the Nrf2/HO-1 pathway to attenuate indoxyl sulfate-induced oxidative stress and DNA damage in renal tubular epithelial cells

Xiaoli Qian
Zhixia Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715462

1,102 views

Original Research

Published on 05 Jan 2026

Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae]

Mariana Andrea Peralta
Einy Nallybe Bedoya Aguirre
Melisa Fabiana Negro
Javier Echeverría
Maria Daniela Santi
Maria Gabriela Ortega

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1717359

576 views

Original Research

Published on 05 Jan 2026

Lauric acid modulates the cyclooxygenases and nitric oxide pathways and reduces oxidative stress in preventing tracheal hyperresponsiveness in asthmatic Wistar rats

Indyra Alencar Duarte Figueiredo
Alissa Maria de Oliveira Martins
Alexya Mikelle Teixeira Cavalcanti
Jayne Muniz Fernandes
Ludmila Emilly da Silva Gomes
Gabriel Nunes Machado de Oliveira
Lucas Nóbrega de Oliveira
Isabela Motta Felício
Adriana Maria Fernandes de Oliveira Golzio
Adriano Francisco Alves

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657799

3,394 views

Systematic Review

Published on 05 Jan 2026

A critical review of systematic reviews and meta-analyses of curcumin for knee osteoarthritis

Jixin Chen
Qinxin Zhou
Weijie Yu
Dongdong Cao
Yingzhou Li
Jianliang Chen
Feng Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664319

1,352 views

Original Research

Published on 05 Jan 2026

Comparison of granule and traditional decoction of Gancao Xiexin for cold-heat complex pattern recurrent oral ulcer: a randomized controlled trial

Si-Run Liu
Hai-Tao Zhu
Pei-Chi Chen
Yu-Yu Zeng
Rui-Min Wang
Hua-Chong Xu
Ze-Jian Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668985

948 views

Mini Review

Published on 05 Jan 2026

Patient-derived organoids in non-small cell lung cancer: advances in drug sensitivity testing

Wanyu Tang
Xudong Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639268

1,121 views

Systematic Review

Published on 05 Jan 2026

Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions

Adriana Monserrath Orellana-Paucar
Erick Thomas Mosquera-Lopez
Nancy Michelle Bustamante-Alvarez
María Gabriela Machado-Orellana
Daniela Alejandra Vintimilla-Rojas
John Diego Atiencia-Palacios
Ana Cristina Espinoza-Fajardo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676685

1,033 views

Original Research

Published on 05 Jan 2026

Study on the correlation between plasma concentration of voriconazole and clinical efficacy and safety in elderly patients

Yueran Li
Huifang Xu
Huifang Wang
Wen Zhang
Yujia Song
Sheng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726902

789 views

Review

Published on 05 Jan 2026

Signaling pathways of marine-derived natural products on lung injury: from the in vivo perspective

Haitong Wang
Feng Qiu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716898

715 views

General Commentary

Published on 05 Jan 2026

Commentary: CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

Wentao Guo
Yun Wang
Danqin Fang
Zhihui Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1750070

513 views

Original Research

Published on 05 Jan 2026

Pharmacovigilance signal detection of psychiatric adverse events induced by third-generation antiepileptic drugs in children

Wenfang Sun
Yali Li
Binbin Xia
Liushui Li
Jing Chen
Yang Liu
Jingyao Pang
Fang Liu
Hua Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1711879

1,013 views

Review

Published on 05 Jan 2026

Dietary polyphenols maintain human health through modulation of gut microbiota

Mithun Rudrapal
André M. de Oliveira
Ravi Pratap Singh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710088

1,921 views
1 citation

Original Research

Published on 05 Jan 2026

Harnessing red grape pomace extract for sustainable broad-spectrum photoprotection in a reconstructed human epidermis model

Antonella Smeriglio
Marta Mangano
Mariarosaria Ingegneri
Annarita La Neve
Chiara Brenna
Luca Mastracci
Francesco Merlino
Giancarlo Tonon
Diego Bosco
Domenico Trombetta

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1744377

549 views

Original Research

Published on 05 Jan 2026

Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis

Sijin Wang
Minghui Zhang
Yao Lu
Peipei Du
Ziwen Xu
Xu Pang
Jierong Gao
Li Li
Chi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730699

925 views

Original Research

Published on 05 Jan 2026

Randomized trial and multi-omics, machine learning–based mechanistic exploration of daixie decoction granules in type 2 diabetes

Zhong Zheng
Kepei Zhang
Xiaogang Ma
Yuezhou Qian
Miao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723584

1,026 views

29,545 Publications

volumes

Volume 16 - 2025

Cost-effectiveness analysis of inavolisib combined with palbociclib plus fulvestrant in PIK3CA-mutated HR+/Her2− advanced breast cancer in China

Comparative efficacy and safety of imrecoxib versus celecoxib: a systematic review and meta-analysis

Maternal influenza vaccination during pregnancy and the risk of adverse pregnancy and birth outcomes

Antibiotic use for respiratory tract infections in nursing homes: a multicentre cross-sectional study

Osteoarthritis: multitissue pathology, molecular mechanisms, clinical management, and emerging precision and regenerative therapies

Different traditional Chinese medicine injections combined with conventional therapy for sepsis-induced myocardial dysfunction: a systematic review and network meta-analysis

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for bimekizumab

Molecular insights into NLRP3 inflammasome and miRNA modulation in oral cancer

The anti-osteoporotic effect of puerarin on the femoral bone in rat models of osteoporosis: a systematic review and meta-analysis

Astaxanthin activates the Nrf2/HO-1 pathway to attenuate indoxyl sulfate-induced oxidative stress and DNA damage in renal tubular epithelial cells

Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae]

Lauric acid modulates the cyclooxygenases and nitric oxide pathways and reduces oxidative stress in preventing tracheal hyperresponsiveness in asthmatic Wistar rats

A critical review of systematic reviews and meta-analyses of curcumin for knee osteoarthritis

Comparison of granule and traditional decoction of Gancao Xiexin for cold-heat complex pattern recurrent oral ulcer: a randomized controlled trial

Patient-derived organoids in non-small cell lung cancer: advances in drug sensitivity testing

Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions

Study on the correlation between plasma concentration of voriconazole and clinical efficacy and safety in elderly patients

Signaling pathways of marine-derived natural products on lung injury: from the in vivo perspective

Commentary: CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

Pharmacovigilance signal detection of psychiatric adverse events induced by third-generation antiepileptic drugs in children

Dietary polyphenols maintain human health through modulation of gut microbiota

Harnessing red grape pomace extract for sustainable broad-spectrum photoprotection in a reconstructed human epidermis model

Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis

Randomized trial and multi-omics, machine learning–based mechanistic exploration of daixie decoction granules in type 2 diabetes