Frontiers in Pharmacology

Systematic Review

Published on 10 Dec 2025

Traditional Chinese medicine for non-alcoholic fatty liver disease: an overview of systematic reviews with evidence mapping and metabolic outcome assessment

Juanjuan Li
Ruimin Jiao
Wenquan Su
Wei Chen
Xiangyu Hu
Shuai Xu
Lie Xu
Weiwei Yao
Kejia Liu
Hong You

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675793

2,212 views

Review

Published on 10 Dec 2025

Biological effects of human placental extracts - variations in manufacturing methods and compositions

Yikelamu Alimu
Takeshi Yamamoto
Yasukazu Nakahata

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707890

2,493 views

Review

Published on 10 Dec 2025

Selected traditional Chinese medicine interventions for post-stroke cerebral edema: a review integrating clinical evidence and mechanistic insights

Junyue Huang
Yujia Jin
Yuping Chen
Mengsi Wang
Jian Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1709821

1,305 views

Original Research

Published on 10 Dec 2025

Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning

Dan Zhu
Jie Zhong
Yarong Liu
Sicheng Zhang
Lianhong Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716911

1,172 views

Review

Published on 10 Dec 2025

Flow cytometric detection of leukemic stem cells in Acute Myeloid Leukemia: current status and future directions

Mariam M. Youssef
Christopher Y. Park

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1724473

1,993 views

Original Research

Published on 10 Dec 2025

Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis

Yan Liu
Lufei Yang
Junxi Liu
Zihao He
Jingyi Wang
Yu Zhang
Kaiping Wang
Jinglin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725716

1,098 views
1 citation

Review

Published on 10 Dec 2025

Therapeutic potential of Abelmoschus manihot: mechanisms of action and clinical use in traditional Chinese medicine formulas

Chu Xue
Haitao Ge
Yaru Liu
Yan Zhao
Wenjie Huang
Zhaowen Lu
Qiuhui Ye
Xiaoli Chen
Zhengyu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1709530

901 views

Original Research

Published on 10 Dec 2025

Off-target autophagy disruption associated with a novel liver toxicity in dogs for a highly basic heterobifunctional protein degrader

James E. Kath
Rebecca Kohnken
Timothy Brayman
Junhai Yang
Katharina Haag
Jingyi Gong
Christopher Untucht
Christiane Imhof
Kenneth P. Robinson
Ryan A. McClure

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664889

2,018 views

Original Research

Published on 10 Dec 2025

Potential lipid-lowering effects of preussin B on inhibition of intestinal cholesterol absorption: integrative mechanisms of action and proteomic analysis

Atcharaporn Ontawong
Jakkapong Inchai
Pannita Holasut
Wararat Chiangjong
Thaweesak Chieochansin
Davide Crucitti
Adrián Mosquera Orgueira
Worarat Rojanaverawong
Thanthakan Saithong
Kornwalai Tunkaew

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708213

1,126 views

Review

Published on 10 Dec 2025

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

Yang Wang
Luyao Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723606

1,574 views

Original Research

Published on 10 Dec 2025

Optimisation of peptides targeting reverse transcriptase HIV-1 using QSAR, machine learning, and computational approaches

Fachrur Rizal Mahendra
Indira Prakoso
Alfa Marzelino
Muhamad Rizqy Fadhillah
Syukriyansyah
Muhammad Marsha Azzami Hasibuan
Juniza Firdha Suparningtyas
Mikael Kristiadi
Aprijal Ghiyas Setiawan
Faris Izzatur Rahman

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707377

2,207 views

Editorial

Published on 09 Dec 2025

Editorial: Innovative approaches for wound treatment

Junxiao Zhang
Shenglin Geng
Guojuan Fan
Jinlong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1738213

758 views

Original Research

Published on 09 Dec 2025

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

Guangyao Li
Tiantian Wang
Dan Tan
Yamin Jin
Xuemei Zhou
Hongru Ai
Xinya Zheng
Xiaochen Ren
Shi Hu
Changhai Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1703805

816 views

Review

Published on 09 Dec 2025

Pharmacological effects and application prospects of mussel adhesive proteins

Junsha An
Zengmiao Hou
Jiaqi Li
Qian Bi
Shile Huang
Cheng Peng
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704475

1,897 views
1 citation

Original Research

Published on 09 Dec 2025

Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse

Ayat Zagzoog
Kenzie Halter
Nini Ha
Alayna M. Jones
Rachel Andres
Andy Kim
Deborah Michel
Jane Alcorn
Robert B. Laprairie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672098

1,957 views

Original Research

Published on 09 Dec 2025

Impact of different doses of rivaroxaban on clinical outcomes in elderly patients with non-valvular atrial fibrillation: a real-world study

Juan Yu
Zufeng Zhang
Qingru Yuan
Haobing Hu
Huimin Li
Meifang Huang
Youlin Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714318

1,649 views

Original Research

Published on 09 Dec 2025

Phoxim induces neurotoxicity and intestinal damage in Caenorhabditis elegans

Mengyuan Zhang
Xin Zhao
Hua Bai
Qi Wang
Wei Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657527

1,318 views

Systematic Review

Published on 09 Dec 2025

Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

Wentao Bian
Mengxia Qi
Lu Ding
Yixuan Lu
Kangling Yan
Ziqi Wang
Jiancheng Zhang
Ping Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1677936

1,451 views

Original Research

Published on 09 Dec 2025

Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide

Rasha A. Tawfiq
Yasmeen M. Attia
Hameis M. Sleem
Mai El-Sayed Ghoneim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610718

1,713 views

Conceptual Analysis

Published on 09 Dec 2025

The night is dark and full of hesitation. The latest step in the legal trajectory of assisted suicide in Italy: through tentative judicial openings, bioethical contradictions and the Parliament’s deafness

Paola Frati
Marco Albore
Eleonora Micaela Ertola
Sossio Del Prete
Letizia Sorace
Raffaele La Russa
Giorgio Bolino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520136

859 views

Original Research

Published on 09 Dec 2025

Cryptotanshinone targets tumor-immune-microbiome axis to suppress colorectal cancer

Zhenya Yang
Mengting Zhou
Fenglin Luo
Shiqi Feng
Yu Tan
Qiqian Wang
Zeneng Cheng
Ruirong Tan
Rui Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667500

1,487 views

Original Research

Published on 09 Dec 2025

Ethnobotany, chemical analysis, and antiglycation activity of Elsholtzia species from Northern Thailand

Angkhana Inta
Pitchaya Mungkornasawakul
Lalida Shank
Wittaya Pongamornkul
Yinxian Shi
Yao Fu
Ruyu Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673250

1,254 views

Editorial

Published on 09 Dec 2025

Editorial: Efficacy and mechanism of herbal medicines and their functional compounds in preventing and treating cardiovascular diseases and cardiovascular disease risk factors-Volume II

Tiantian Meng
Yuqing Zhang
Jie Wang
Chen Huei Leo
Zhongfeng Li
Jian Zhang
Kuo Gao
Qingyong He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1742260

881 views

Correction

Published on 08 Dec 2025

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

Zhijun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1756716

1,069 views

29,570 Publications

volumes

Volume 16 - 2025

Traditional Chinese medicine for non-alcoholic fatty liver disease: an overview of systematic reviews with evidence mapping and metabolic outcome assessment

Biological effects of human placental extracts - variations in manufacturing methods and compositions

Selected traditional Chinese medicine interventions for post-stroke cerebral edema: a review integrating clinical evidence and mechanistic insights

Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning

Flow cytometric detection of leukemic stem cells in Acute Myeloid Leukemia: current status and future directions

Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis

Therapeutic potential of Abelmoschus manihot: mechanisms of action and clinical use in traditional Chinese medicine formulas

Off-target autophagy disruption associated with a novel liver toxicity in dogs for a highly basic heterobifunctional protein degrader

Potential lipid-lowering effects of preussin B on inhibition of intestinal cholesterol absorption: integrative mechanisms of action and proteomic analysis

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

Optimisation of peptides targeting reverse transcriptase HIV-1 using QSAR, machine learning, and computational approaches

Editorial: Innovative approaches for wound treatment

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

Pharmacological effects and application prospects of mussel adhesive proteins

Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse

Impact of different doses of rivaroxaban on clinical outcomes in elderly patients with non-valvular atrial fibrillation: a real-world study

Phoxim induces neurotoxicity and intestinal damage in Caenorhabditis elegans

Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide

The night is dark and full of hesitation. The latest step in the legal trajectory of assisted suicide in Italy: through tentative judicial openings, bioethical contradictions and the Parliament’s deafness

Cryptotanshinone targets tumor-immune-microbiome axis to suppress colorectal cancer

Ethnobotany, chemical analysis, and antiglycation activity of Elsholtzia species from Northern Thailand

Editorial: Efficacy and mechanism of herbal medicines and their functional compounds in preventing and treating cardiovascular diseases and cardiovascular disease risk factors-Volume II

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway