Frontiers in Pharmacology

Original Research

Published on 08 Jan 2025

Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database

Qian Qiao
Jiachen Sun
Ya Zheng
Yingying Mi
Yanan Gong
Jiahui Liu
Wenyue Rui
Yumei Ma
Yongning Zhou
Min Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1507196

3,221 views

Original Research

Published on 08 Jan 2025

ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathway

Jiali Hu
Jing Cao
Shanshan Huang
Yang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1536478

2,394 views
5 citations

Original Research

Published on 08 Jan 2025

Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway

Rumeng Ding
Quancheng Kan
Ting Wang
Ran Xiao
Yanan Song
Duolu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1483896

4,025 views
5 citations

Clinical Trial

Published on 08 Jan 2025

Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study

Wei Ji
Liping Sun
Yue Huang
Jie Bai
Jijian Zheng
Kan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515501

1,941 views

Review

Published on 08 Jan 2025

Kleinia (Asteraceae): comprehensive review of ethnomedicinal uses, phytochemical profiles, ethnopharmacological applications, and toxicological insights

Bantayehu Addis Tegegne
Tesfa Begashaw
Wubetu Yihunie Belay
Mengistie Kassahun Tariku
Tirsit Ketsela Zeleke
Mohammed Jemal
Mamaru Getinet
Agumas Alemu Alehegn
Abebe Dagne

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1469887

4,310 views
1 citation

Original Research

Published on 08 Jan 2025

Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease

Ting-Ting Li
Li-Ying Wen
Sha-Sha Meng
Yu-Sang Li
He-Bin Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476735

2,429 views
1 citation

Original Research

Published on 08 Jan 2025

Anti-inflammatory and antioxidant properties of oleuropein in human keratinocytes characterized by bottom-up proteomics

Huifang Li
Ni Deng
Jiayi Yang
Yang Zhao
Xiaoxuan Jin
Ang Cai
Navindra P. Seeram
Hang Ma
Dongli Li
Huilan Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496078

3,110 views
4 citations

Original Research

Published on 08 Jan 2025

Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microbiota

Yunjiao Shen
Yansong Gao
Ge Yang
Zijian Zhao
Yujuan Zhao
Lei Gao
Shengyu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496346

2,622 views

Original Research

Published on 08 Jan 2025

The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist

Xiaoting Gu
Xiaohe Li
Weixue Tian
Chaoyue Zheng
Yutian Cai
Xiang Xu
Conglu Zhao
Hongting Liu
Yao Sun
Zhilin Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1510903

1,901 views

Review

Published on 08 Jan 2025

Natural pigments: innovative extraction technologies and their potential application in health and food industries

Ayu Masyita
Gemala Hardinasinta
Ayun Dwi Astuti
Firdayani Firdayani
Dian Mayasari
Aki Hori
Ira Nur Ainun Nisha
Firzan Nainu
Takayuki Kuraishi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1507108

14,675 views
16 citations

Original Research

Published on 08 Jan 2025

Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway

Gang Liu
Bin-Bin Dong
Zi-Heng Ding
Chao Lan
Chang-Ju Zhu
Qi Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1469783

2,017 views
1 citation

Original Research

Published on 08 Jan 2025

stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments

Roberto Visintainer
Anna Fochesato
Daniele Boaretti
Stefano Giampiccolo
Shayne Watson
Micha Levi
Federico Reali
Luca Marchetti

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462193

1,567 views

Original Research

Published on 08 Jan 2025

Safety of combined drug use in patients with cardiovascular and cerebrovascular diseases: an analysis based on the spontaneous reporting database of adverse drug reactions in Hubei Province

Jia Wang
Yuhang Zhao
Zherui Chen
Rui Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451713

2,637 views
1 citation

Systematic Review

Published on 08 Jan 2025

Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials

Weijie Fu
Maolin Zhao
Sheng Ding
Mei Xin
Ke Yang
Li Jiang
Fan Wu
Xiaochen Wu
Jian Wang
Jie Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1519869

4,572 views
1 citation

Original Research

Published on 08 Jan 2025

Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends

Hong-Yu Jiang
Bo Shao
Hong-Da Wang
Wen-Qi Zhao
Shao-Hua Ren
Yi-Ni Xu
Tong Liu
Cheng-Lu Sun
Yi-Yi Xiao
Yi-Cheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1523052

4,411 views
2 citations

Original Research

Published on 08 Jan 2025

Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway

Yumei Rong
Minghui Zhu
Nan Wang
Feiyu Zhang
Tianjun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1539363

2,105 views
2 citations

Review

Published on 07 Jan 2025

Gallic acid: a dietary metabolite’s therapeutic potential in the management of atherosclerotic cardiovascular disease

Xiao-Lan Zhao
Zhang-Jing Cao
Ke-Di Li
Fei Tang
Li-Yue Xu
Jing-Nan Zhang
Dong Liu
Cheng Peng
Hui Ao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515172

4,589 views
7 citations

Original Research

Published on 07 Jan 2025

Appropriateness and inappropriate medication predictors of stress ulcer prophylaxis in the intensive care unit

Pan Zhang
Siyang Wang
Tingting Zhi
Naobei Ye
Haonan Sun
Xingyu Qin
Shuhan Xu
Ruiqin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1401335

2,207 views
1 citation

Original Research

Published on 07 Jan 2025

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia

Mihaela Butiulca
Lenard Farczadi
Silvia Imre
Camil Eugen Vari
Laurian Vlase
Bogdan Cordos
Leonard Azamfirei
Alexandra Elena Lazar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494646

1,680 views
1 citation

Review

Published on 07 Jan 2025

Radix Codonopsis: a review of anticancer pharmacological activities

Cai-Yue Liu
Zheng Li
Fan-E. Cheng
Yi Nan
Wei-Qiang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1498707

3,689 views
5 citations

Original Research

Published on 07 Jan 2025

A randomized sequential allocation study on the optimum programmed intermittent epidural boluses interval time with different concentrations of ropivacaine combined with the dural puncture epidural technique for labor analgesia

Jingjing Mao
Yi Chen
Linsen Sun
Xiaoxiao Xu
Kai Xu
Tingting Ren
Xiangsheng Xiong
Weibing Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1508514

1,595 views
3 citations

Original Research

Published on 07 Jan 2025

Efficiency and safety of HAIC combined with lenvatinib and tislelizumab for advanced hepatocellular carcinoma with high tumor burden: a multicenter propensity score matching analysis

Zhonghua Zhao
Xiongying Jiang
Shiping Wen
Yanzhang Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499269

2,416 views
1 citation

Case Report

Published on 07 Jan 2025

Ceftriaxone-induced hemolytic anemia managed successfully in a 54-year-old woman: a case report and literature review

Liqian Zhang
Wenfeng Huang
Jiakai Xu
Yunxing Li
Jihong Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505366

2,364 views
2 citations

Review

Published on 07 Jan 2025

The efficacy of core decompression combined with regenerative therapy in early femoral head necrosis: a systematic review and meta-analysis involving 954 subjects

Haiwei Tang
Tingxian Ling
Enze Zhao
Mingke You
Xi Chen
Gang Chen
Kai Zhou
Zongke Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1501590

4,284 views
7 citations

3,490 Publications

volumes

Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database

ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathway

Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway

Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study

Kleinia (Asteraceae): comprehensive review of ethnomedicinal uses, phytochemical profiles, ethnopharmacological applications, and toxicological insights

Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease

Anti-inflammatory and antioxidant properties of oleuropein in human keratinocytes characterized by bottom-up proteomics

Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microbiota

The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist

Natural pigments: innovative extraction technologies and their potential application in health and food industries

Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway

stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments

Safety of combined drug use in patients with cardiovascular and cerebrovascular diseases: an analysis based on the spontaneous reporting database of adverse drug reactions in Hubei Province

Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials

Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends

Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway

Gallic acid: a dietary metabolite’s therapeutic potential in the management of atherosclerotic cardiovascular disease

Appropriateness and inappropriate medication predictors of stress ulcer prophylaxis in the intensive care unit

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia

Radix Codonopsis: a review of anticancer pharmacological activities

A randomized sequential allocation study on the optimum programmed intermittent epidural boluses interval time with different concentrations of ropivacaine combined with the dural puncture epidural technique for labor analgesia

Efficiency and safety of HAIC combined with lenvatinib and tislelizumab for advanced hepatocellular carcinoma with high tumor burden: a multicenter propensity score matching analysis

Ceftriaxone-induced hemolytic anemia managed successfully in a 54-year-old woman: a case report and literature review

The efficacy of core decompression combined with regenerative therapy in early femoral head necrosis: a systematic review and meta-analysis involving 954 subjects