Frontiers in Pharmacology

Original Research

Published on 21 Jan 2022

Spontaneous Activity of CB2 Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice

Melissa A. Ribeiro
Rafael P. Aguiar
Franciele F. Scarante
Eduardo J. Fusse
Rubia M. W. de Oliveira
Francisco S. Guimaraes
Alline C Campos

Frontiers in Pharmacology

doi 10.3389/fphar.2021.805758

3,762 views
17 citations

Original Research

Published on 21 Jan 2022

Activation of the STAT5 Signaling Pathway by Yiqi Jiedu Formula Induces Regulatory T Cell-Mediated Alleviation of Corneal Immunopathological Damage in Mice With Recurrent Herpes Simplex Keratitis

Shuyu Xiao
Yang Yang
Wanhong Miao
Chunming Lyu
Jinhua Tao
Ying Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.790787

3,715 views
5 citations

Mini Review

Published on 21 Jan 2022

Anti-Allergic Properties of Propolis: Evidence From Preclinical and Clinical Studies

Kong Yen Liew
Nurain Irdayani Kamise
Hui Ming Ong
Poi Yi Aw Yong
Fahmida Islam
Ji Wei Tan
Chau Ling Tham

Frontiers in Pharmacology

doi 10.3389/fphar.2021.785371

35,787 views
28 citations

Systematic Review

Published on 21 Jan 2022

Specific Interleukin-1 Inhibitors, Specific Interleukin-6 Inhibitors, and GM-CSF Blockades for COVID-19 (at the Edge of Sepsis): A Systematic Review

Ying Wang
Kun Zhu
Rulin Dai
Rui Li
Miao Li
Xin Lv
Qian Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.804250

7,168 views
26 citations

Systematic Review

Published on 21 Jan 2022

Does Having a Usual Primary Care Provider Reduce Polypharmacy Behaviors of Patients With Chronic Disease? A Retrospective Study in Hubei Province, China

Jia Wang
Zhanchun Feng
Zhongxin Dong
Wanping Li
Chaoyi Chen
Zhichun Gu
Anhua Wei
Da Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.802097

5,293 views
11 citations

Original Research

Published on 21 Jan 2022

Rivastigmine Regulates the HIF-1α/VEGF Signaling Pathway to Induce Angiogenesis and Improves the Survival of Random Flaps in Rats

Yingying Liu
Wenjie Li
Xinyi Ma
Jibing He
Yi Lin
Dingsheng Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.818907

4,811 views
19 citations

Review

Published on 21 Jan 2022

Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis

Cristina Estornut
Javier Milara
María Amparo Bayarri
Nada Belhadj
Julio Cortijo

Frontiers in Pharmacology

doi 10.3389/fphar.2021.794997

16,917 views
117 citations

Review

Published on 21 Jan 2022

Cationic Nanomaterials for Autoimmune Diseases Therapy

Baozhao Xie
Keqian Du
Fujian Huang
Zhiming Lin
Linping Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.762362

5,193 views
19 citations

Correction

Published on 21 Jan 2022

Corrigendum: The Mechanisms of Cucurbitacin E as a Neuroprotective and Memory-Enhancing Agent in a Cerebral Hypoperfusion Rat Model: Attenuation of Oxidative Stress, Inflammation, and Excitotoxicity

Zhiyong Liu
Manish Kumar
Sushma Devi
Atul Kabra

Frontiers in Pharmacology

doi 10.3389/fphar.2021.844464

1,795 views
1 citation

Original Research

Published on 21 Jan 2022

Tumor Necrosis Factor Alpha -308G/A Gene Polymorphisms Combined with Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratio Predicts the Efficacy and Safety of Anti-TNF-α Therapy in Patients with Ankylosing Spondylitis, Rheumatoid Arthritis, and Psoriasis Arthritis

Ziran Wang
Lingjun Kong
Han Zhang
Fengchun Sun
Zijian Guo
Rui Zhang
Yaling Dou

Frontiers in Pharmacology

doi 10.3389/fphar.2021.811719

5,821 views
26 citations

Review

Published on 20 Jan 2022

Molecular Targets for Novel Therapeutics in Pediatric Fusion-Positive Non-CNS Solid Tumors

Wen-I Chang
Claire Lin
Nicholas Liguori
Joshua N. Honeyman
Bradley DeNardo
Wafik El-Deiry

Frontiers in Pharmacology

doi 10.3389/fphar.2021.747895

8,137 views
16 citations

Systematic Review

Published on 20 Jan 2022

Neglected and Underutilised Crops: A Systematic Review of Their Potential as Food and Herbal Medicinal Crops in South Africa

Fhatuwani Nixwell Mudau
Vimbayi Grace Petrova Chimonyo
Albert Thembinkosi Modi
Tafadzwanashe Mabhaudhi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.809866

27,357 views
63 citations

Original Research

Published on 20 Jan 2022

Kangbainian Lotion Ameliorates Vulvovaginal Candidiasis in Mice by Inhibiting the Growth of Fluconazole-Resistant Candida albicans and the Dectin-1 Signaling Pathway Activation

Zewei Chen
Tengshuo Luo
Fengke Huang
Fuzhen Yang
Wenting Luo
Guanfeng Chen
Mengfei Cao
Fengyun Wang
Jun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.816290

4,735 views
11 citations

Systematic Review

Published on 20 Jan 2022

Anti-Remodeling Cardiac Therapy in Patients With Duchenne Muscular Dystrophy, Meta-Analysis Study

Bruria Hirsh Raccah
Bar Biton
Offer Amir
Israel Gotsman
Dean Nahman
Ilan Matok

Frontiers in Pharmacology

doi 10.3389/fphar.2021.769896

5,396 views
2 citations

Original Research

Published on 20 Jan 2022

Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke

Huiting Lin
Shaoru Chen
Lin Shen
Tao Hu
Jiale Cai
Sikai Zhan
Jiayin Liang
Mingmin Huang
Minghua Xian
Shumei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.773722

8,565 views
28 citations

Review

Published on 20 Jan 2022

Bulbus Fritillariae Cirrhosae as a Respiratory Medicine: Is There a Potential Drug in the Treatment of COVID-19?

Yunyun Quan
Li Li
Zhujun Yin
Shilong Chen
Jing Yi
Jirui Lang
Lu Zhang
Qianhua Yue
Junning Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.784335

28,022 views
24 citations

Correction

Published on 20 Jan 2022

Corrigendum: Prevention of Cyclophosphamide-Induced Immunosuppression in Mice With Traditional Chinese Medicine Xuanfei Baidu Decoction

Huimin Yan
Jia Lu
Jiabao Wang
Lu Chen
Yu Wang
Lin Li
Lin Miao
Han Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.808424

2,072 views

Mini Review

Published on 20 Jan 2022

Platelet Mechanobiology Inspired Microdevices: From Hematological Function Tests to Disease and Drug Screening

Yingqi Zhang
Fengtao Jiang
Yunfeng Chen
Lining Arnold Ju

Frontiers in Pharmacology

doi 10.3389/fphar.2021.779753

5,469 views
14 citations

Review

Published on 20 Jan 2022

Evolution of a Paradigm Switch in Diagnosis and Treatment of HPV-Driven Head and Neck Cancer—Striking the Balance Between Toxicity and Cure

Bouchra Tawk
Jürgen Debus
Amir Abdollahi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.753387

8,846 views
25 citations

Systematic Review

Published on 20 Jan 2022

Efficacy and Safety of Ertugliflozin in Type 2 Diabetes: A Systematic Review and Meta-Analysis

Li Liu
Fang-Hong Shi
Hua Xu
Yue Wu
Zhi-Chun Gu
Hou-Wen Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.752440

7,690 views
17 citations

Brief Research Report

Published on 20 Jan 2022

Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study

Guilherme Grossi Lopes Cançado
Cláudia Alves Couto
Laura Vilar Guedes
Michelle Harriz Braga
Débora Raquel Benedita Terrabuio
Eduardo Luiz Rachid Cançado
Maria Lucia Gomes Ferraz
Cristiane Alves Villela-Nogueira
Mateus Jorge Nardelli
Luciana Costa Faria

Frontiers in Pharmacology

doi 10.3389/fphar.2021.818089

6,651 views
12 citations

Systematic Review

Published on 20 Jan 2022

Efficacy and Safety of Chinese Herbal Medicine Xiao Yao San in Functional Gastrointestinal Disorders: A meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials

Qian Liu
Zongming Shi
Tao Zhang
Tianyuan Jiang
Xiaoying Luo
Xiaolan Su
Yang Yang
Wei Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2021.821802

10,539 views
16 citations

Original Research

Published on 20 Jan 2022

Acute Oral, Subacute, and Developmental Toxicity Profiling of Naphthalene 2-Yl, 2-Chloro, 5-Nitrobenzoate: Assessment Based on Stress Response, Toxicity, and Adverse Outcome Pathways

Fareeha Anwar
Uzma Saleem
Atta ur rehman
Bashir Ahmad
Tariq Ismail
Muhammad Usman Mirza
Sarfraz Ahmad

Frontiers in Pharmacology

doi 10.3389/fphar.2021.810704

7,468 views
20 citations

Review

Published on 20 Jan 2022

From Bedside to the Bench—A Call for Novel Approaches to Prognostic Evaluation and Treatment of Empyema

Sophia Karandashova
Galina Florova
Steven Idell
Andrey A. Komissarov

Frontiers in Pharmacology

doi 10.3389/fphar.2021.806393

6,256 views
5 citations

4,137 Publications

volumes

Spontaneous Activity of CB2 Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice

Activation of the STAT5 Signaling Pathway by Yiqi Jiedu Formula Induces Regulatory T Cell-Mediated Alleviation of Corneal Immunopathological Damage in Mice With Recurrent Herpes Simplex Keratitis

Anti-Allergic Properties of Propolis: Evidence From Preclinical and Clinical Studies

Specific Interleukin-1 Inhibitors, Specific Interleukin-6 Inhibitors, and GM-CSF Blockades for COVID-19 (at the Edge of Sepsis): A Systematic Review

Does Having a Usual Primary Care Provider Reduce Polypharmacy Behaviors of Patients With Chronic Disease? A Retrospective Study in Hubei Province, China

Rivastigmine Regulates the HIF-1α/VEGF Signaling Pathway to Induce Angiogenesis and Improves the Survival of Random Flaps in Rats

Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis

Cationic Nanomaterials for Autoimmune Diseases Therapy

Corrigendum: The Mechanisms of Cucurbitacin E as a Neuroprotective and Memory-Enhancing Agent in a Cerebral Hypoperfusion Rat Model: Attenuation of Oxidative Stress, Inflammation, and Excitotoxicity

Tumor Necrosis Factor Alpha -308G/A Gene Polymorphisms Combined with Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratio Predicts the Efficacy and Safety of Anti-TNF-α Therapy in Patients with Ankylosing Spondylitis, Rheumatoid Arthritis, and Psoriasis Arthritis

Molecular Targets for Novel Therapeutics in Pediatric Fusion-Positive Non-CNS Solid Tumors

Neglected and Underutilised Crops: A Systematic Review of Their Potential as Food and Herbal Medicinal Crops in South Africa

Kangbainian Lotion Ameliorates Vulvovaginal Candidiasis in Mice by Inhibiting the Growth of Fluconazole-Resistant Candida albicans and the Dectin-1 Signaling Pathway Activation

Anti-Remodeling Cardiac Therapy in Patients With Duchenne Muscular Dystrophy, Meta-Analysis Study

Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke

Bulbus Fritillariae Cirrhosae as a Respiratory Medicine: Is There a Potential Drug in the Treatment of COVID-19?

Corrigendum: Prevention of Cyclophosphamide-Induced Immunosuppression in Mice With Traditional Chinese Medicine Xuanfei Baidu Decoction

Platelet Mechanobiology Inspired Microdevices: From Hematological Function Tests to Disease and Drug Screening

Evolution of a Paradigm Switch in Diagnosis and Treatment of HPV-Driven Head and Neck Cancer—Striking the Balance Between Toxicity and Cure

Efficacy and Safety of Ertugliflozin in Type 2 Diabetes: A Systematic Review and Meta-Analysis

Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study

Efficacy and Safety of Chinese Herbal Medicine Xiao Yao San in Functional Gastrointestinal Disorders: A meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials

Acute Oral, Subacute, and Developmental Toxicity Profiling of Naphthalene 2-Yl, 2-Chloro, 5-Nitrobenzoate: Assessment Based on Stress Response, Toxicity, and Adverse Outcome Pathways

From Bedside to the Bench—A Call for Novel Approaches to Prognostic Evaluation and Treatment of Empyema