Frontiers in Pharmacology

Original Research

Published on 03 Jan 2024

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

Huaqiang Bi
Kai Feng
Xiaofei Wang
Ping Zheng
Chengming Qu
Kuansheng Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304996

2,295 views
1 citation

Systematic Review

Published on 03 Jan 2024

Nanomedicine drug delivery in South Africa: a retrospective study on research, funding and collaboration

Faatiema Salie
Trust Saidi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1317137

3,290 views
6 citations

Review

Published on 03 Jan 2024

The application and sustainable development of coral in traditional medicine and its chemical composition, pharmacology, toxicology, and clinical research

Mengtian Han
Zhongyuan Wang
Yiye Li
Yinglian Song
Zhang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1230608

26,682 views
9 citations

Case Report

Published on 03 Jan 2024

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

Olga Rogozina
Carmen Ruiz-Fernández
Susana Martín-López
Ibtissam Akatbach-Bousaid
Miguel González-Muñoz
Elena Ramírez

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1293294

3,806 views
7 citations

Original Research

Published on 03 Jan 2024

Ameliorative inhibition of sirtuin 6 by imidazole derivative triggers oxidative stress-mediated apoptosis associated with Nrf2/Keap1 signaling in non-small cell lung cancer cell lines

Uma Maheswara Rao Dindi
Sameer Al-Ghamdi
Naif Abdurhman Alrudian
Salman Bin Dayel
Abdulwahab Ali Abuderman
Mohammed Saad Alqahtani
Nasraddin Othman Bahakim
Thiyagarajan Ramesh
Ravikumar Vilwanathan

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1335305

3,624 views
6 citations

Original Research

Published on 03 Jan 2024

Renal and survival benefits of seventeen prescribed Chinese herbal medicines against oxidative-inflammatory stress in systemic lupus erythematosus patients with chronic kidney disease: a real-world longitudinal study

Hsiao-Tien Chen
Chien-Hsueh Tung
Ben-Hui Yu
Ching-Mao Chang
Yi-Chun Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1309582

4,462 views
11 citations

Original Research

Published on 03 Jan 2024

The protective effect of PL 1-3 on D-galactose-induced aging mice

Pengxiao Li
Yazhong Ma
Xiaotong Wang
Xin Li
Xuekun Wang
Jie Yang
Guoyun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304801

5,997 views
10 citations

Original Research

Published on 03 Jan 2024

Cardiac miRNA expression during the development of chronic anthracycline-induced cardiomyopathy using an experimental rabbit model

Michaela Adamcova
Helena Parova
Olga Lencova-Popelova
Petra Kollarova-Brazdova
Ivana Baranova
Marcela Slavickova
Tereza Stverakova
Petra Sauer Mikyskova
Yvona Mazurova
Martin Sterba

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1298172

2,399 views
5 citations

Original Research

Published on 03 Jan 2024

Klotho-derived peptide KP1 ameliorates SARS-CoV-2-associated acute kidney injury

Jie Xu
Enqing Lin
Xue Hong
Li Li
Jun Gu
Jinghong Zhao
Youhua Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1333389

4,955 views
10 citations

Review

Published on 03 Jan 2024

Challenges in management of refractory pain and sedation in infants

Alexandra Oschman
Karishma Rao

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1259064

5,528 views
7 citations

Original Research

Published on 03 Jan 2024

Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology

Iméne Ben Toumia
Tiziana Bachetti
Leila Chekir-Ghedira
Aldo Profumo
Marco Ponassi
Alessandro Di Domizio
Alberto Izzotti
Salvatore Sciacca
Caterina Puglisi
Stefano Forte

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1258108

5,099 views
3 citations

Original Research

Published on 03 Jan 2024

Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria

Xiaojuan Zhu
Feng Zhang
Yong Zhao
Wen Zhang
Yahui Zhang
Jianchun Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1265463

4,748 views
9 citations

Mini Review

Published on 03 Jan 2024

Potential applications of JAK inhibitors, clinically approved drugs against autoimmune diseases, in cancer therapy

Xiao-Huan Wei
Yuan-Yuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326281

9,473 views
16 citations

Original Research

Published on 03 Jan 2024

Stevens’ Cure (Umckaloabo)—the vindication of a patent medicine

T. Brendler
M. A. Stander
B.-E. van Wyk

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1294997

4,804 views
2 citations

Original Research

Published on 03 Jan 2024

Iron scavenging and suppression of collagen cross-linking underlie antifibrotic effects of carnosine in the heart with obesity

Islam A. Berdaweel
T. Blake Monroe
Amany A. Alowaisi
Jolonda C. Mahoney
I-Chau Liang
Kaitlyn A. Berns
Dylan Gao
Jared M. McLendon
Ethan J. Anderson

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1275388

5,109 views
3 citations

Original Research

Published on 03 Jan 2024

Anti-platelet aggregation activities of different grades of Angelica sinensis and their therapeutic mechanisms in rats with blood deficiency: insights from metabolomics and lipidomics analyses

Xue Shen
Yangyang Wu
Ping Chen
Yuwei Bai
Yanan Liu
Yihan Jiang
Yawen Zhang
Zhigang Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1230861

3,665 views
6 citations

Original Research

Published on 29 Dec 2023

Population pharmacokinetics and individualized dosing of vancomycin for critically ill patients receiving continuous renal replacement therapy: the role of residual diuresis

Zhenwei Yu
Jieqiong Liu
Haitao Yu
Ling Zhou
Jianping Zhu
Gang Liang
Yi Yang
Ying Zheng
Yun Han
Junjun Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1298397

4,533 views
3 citations

Original Research

Published on 27 Dec 2023

A glycoengineered therapeutic anti-HBV antibody that allows increased HBsAg immunoclearance improves HBV suppression in vivo

Min You
Fentian Chen
Chao Yu
Yuanzhi Chen
Yue Wang
Xue Liu
Xueran Guo
Bing Zhou
Xin Wang
Boya Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1213726

3,486 views

Original Research

Published on 27 Dec 2023

Research on the quality markers of antioxidant activity of Kai-Xin-San based on the spectrum–effect relationship

Xiaoxiao Shan
Xuan Yang
Dawei Li
Lele Zhou
Shaogang Qin
Junying Li
Wenkang Tao
Can Peng
Jinming Wei
Xiaoqin Chu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1270836

4,179 views
8 citations

Original Research

Published on 27 Dec 2023

Microalgae (Chlorella vulgaris) attenuates aflatoxin-associated renal injury

Ahmed Abdeen
Rasha Elsabagh
Sawsan S. Elbasuni
Alshaimaa M. Said
Afaf Abdelkader
Ali H. El-Far
Samah F. Ibrahim
Ostan Mihaela
Liana Fericean
Abdelfattah M. Abdelfattah

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1291965

3,927 views
6 citations

Clinical Trial

Published on 22 Dec 2023

Evaluating the bioequivalence and safety of liraglutide injection versus Victoza® in healthy Chinese subjects: a randomized, open, two-cycle, self-crossover phase I clinical trial

Chao Liu
Hongrong Xu
Fei Yuan
Hanjing Chen
Lei Sheng
Weili Chen
Haisong Xie
Hongmei Xu
Xuening Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326865

6,859 views
3 citations

Systematic Review

Published on 22 Dec 2023

The current view of potentially inappropriate medications (PIMs) among older adults in Saudi Arabia: a systematic review

Fawaz M. Alotaibi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1325871

3,710 views
3 citations

Original Research

Published on 22 Dec 2023

Identification of oral therapeutics using an AI platform against the virus responsible for COVID-19, SARS-CoV-2

Adam Bess
Frej Berglind
Supratik Mukhopadhyay
Michal Brylinski
Chris Alvin
Fanan Fattah
Kishor M. Wasan

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1297924

5,579 views
5 citations

Original Research

Published on 22 Dec 2023

Casuarina glauca branchlets’ extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies

Maged E. Mohamed
Azza M. El-Shafae
Eman Fikry
Samar S. Elbaramawi
Mahmoud H. Elbatreek
Nora Tawfeek

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1322181

6,147 views
6 citations

3,308 Publications

volumes

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

Nanomedicine drug delivery in South Africa: a retrospective study on research, funding and collaboration

The application and sustainable development of coral in traditional medicine and its chemical composition, pharmacology, toxicology, and clinical research

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

Ameliorative inhibition of sirtuin 6 by imidazole derivative triggers oxidative stress-mediated apoptosis associated with Nrf2/Keap1 signaling in non-small cell lung cancer cell lines

Renal and survival benefits of seventeen prescribed Chinese herbal medicines against oxidative-inflammatory stress in systemic lupus erythematosus patients with chronic kidney disease: a real-world longitudinal study

The protective effect of PL 1-3 on D-galactose-induced aging mice

Cardiac miRNA expression during the development of chronic anthracycline-induced cardiomyopathy using an experimental rabbit model

Klotho-derived peptide KP1 ameliorates SARS-CoV-2-associated acute kidney injury

Challenges in management of refractory pain and sedation in infants

Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology

Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria

Potential applications of JAK inhibitors, clinically approved drugs against autoimmune diseases, in cancer therapy

Stevens’ Cure (Umckaloabo)—the vindication of a patent medicine

Iron scavenging and suppression of collagen cross-linking underlie antifibrotic effects of carnosine in the heart with obesity

Anti-platelet aggregation activities of different grades of Angelica sinensis and their therapeutic mechanisms in rats with blood deficiency: insights from metabolomics and lipidomics analyses

Population pharmacokinetics and individualized dosing of vancomycin for critically ill patients receiving continuous renal replacement therapy: the role of residual diuresis

A glycoengineered therapeutic anti-HBV antibody that allows increased HBsAg immunoclearance improves HBV suppression in vivo

Research on the quality markers of antioxidant activity of Kai-Xin-San based on the spectrum–effect relationship

Microalgae (Chlorella vulgaris) attenuates aflatoxin-associated renal injury

Evaluating the bioequivalence and safety of liraglutide injection versus Victoza® in healthy Chinese subjects: a randomized, open, two-cycle, self-crossover phase I clinical trial

The current view of potentially inappropriate medications (PIMs) among older adults in Saudi Arabia: a systematic review

Identification of oral therapeutics using an AI platform against the virus responsible for COVID-19, SARS-CoV-2

Casuarina glauca branchlets’ extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies