Frontiers in Pharmacology

Original Research

Published on 10 Feb 2025

Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic pathways and BDNF expression

Hart Mann Alain Youbi Mambou
Simon Pale
Orelien Sylvain Mtopi Bopda
Vanessa Tita Jugha
Nji Seraphin Ombel Musa
Tambong Ako Ojongnkpot
Bertrand Yuwong Wanyu
Raymond Bess Bila
Rashed N. Herqash
Abdelaaty A. Shahat

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1301002

Original Research

Published on 05 Feb 2025

Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition

Sajida Parveen
Kashif ur Rehman Khan
Shahid Muhammad Iqbal
Hanan Y. Aati
Areej M. Al-taweel
Liaqat Hussain
Musaddique Hussain

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500085

273 views

Original Research

Published on 05 Feb 2025

Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish

Xiaoqi Pan
Tianyu Liang
Han Feng
Weiying Liu
Qiaoxin Mou
Xiaoyu Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500527

138 views

Policy and Practice Reviews

Published on 03 Feb 2025

Climate change and the sustainable use of medicinal plants: a call for “new” research strategies

Olha Mykhailenko
Banaz Jalil
Lyndy J. McGaw
Javier Echeverría
Marce Takubessi
Michael Heinrich

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496792

710 views

Original Research

Published on 03 Feb 2025

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

Kohen Goble
Aarav Mehta
Damien Guilbaud
Jacob Fessler
Jingting Chen
William Nenad
Christina G. Ford
Oliver Cope
Darby Cheng
William Dennis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516621

238 views

Original Research

Published on 31 Jan 2025

Hu-lu-su-pian ameliorates hepatic steatosis by regulating CIDEA expression in AKT-driven MASLD mice

Rumeng Ren
Qi Wang
Dongjie Deng
Aoao Guo
Xin Chen
Yan Meng
Ying Fang
Guohua Zheng
Zhong Xu
Man Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1503247

266 views

Original Research

Published on 31 Jan 2025

Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice

Jiyao Zhao
Wei Shi
Yan Zheng
Junjie Wang
Muzhao Yuan
Yultuz Anwar
Yuxuan He
Haiping Ma
Jianjiang Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506401

218 views

Brief Research Report

Published on 31 Jan 2025

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

Valentina N. Nikolić
Milan Stefanović
Dejan Mitić
Slavica Sunarić
Vladana Stojiljkovic
Hristina Trajković
Aleksandra Ignjatović
Dragana Stokanović

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505022

257 views

Original Research

Published on 30 Jan 2025

FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage

Fan Wang
Yue Xu
Yajie Wang
Qian Liu
Yanan Li
Weiwei Zhang
Huiming Nong
Junhong Zhang
Hao Zhao
Huaqian Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462421

258 views

Original Research

Published on 30 Jan 2025

Effects of dexmedetomidine-ropivacaine assisted combined spinal-epidural anesthesia on neutrophil-lymphocyte ratio and postoperative delirium in elderly patients with intertrochanteric femoral fracture

Lili Bai
Lina Zhao
Fang Jia
Ying Liu
Ping Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454452

196 views

Original Research

Published on 30 Jan 2025

Ethanol extract of Polygonatum cyrtonema Hua mitigates non-alcoholic steatohepatitis in mice

Dongliang Chen
Yue Shen
Fang Huang
Bo Huang
Shangfu Xu
Lisheng Li
Jie Liu
Zheng Li
Xia Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1487738

209 views

Review

Published on 30 Jan 2025

The enigmatic SLC26A6 multifunctional anion transporter: recent advances in structure-function relationship, pathophysiological significance and novel pharmacological inhibitors

Ursula E. Seidler

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1536864

203 views

Original Research

Published on 29 Jan 2025

Population dynamics analysis of the interaction between tacrolimus and voriconazole in renal transplant recipients

Zhi-Hua Sun
Yi-Chang Zhao
Jia-Kai Li
Fenghua Peng
Feng Yu
Bi-Kui Zhang
Miao Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1502097

187 views

Original Research

Published on 29 Jan 2025

Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study

Li-Qiong Chen
Yong-Can Zhou
Fang Ning
Ming-Jin Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1495957

251 views

Original Research

Published on 29 Jan 2025

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells

Jianfen Shen
Shuo Zhang
Yan Song
Leiming Yang
Qi Huang
Pengyu Wang
Youzhi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1531220

162 views

Correction

Published on 29 Jan 2025

Corrigendum: Polydatin ameliorates early brain injury after subarachnoid hemorrhage through up-regulating SIRT1 to suppress endoplasmic reticulum stress

Yuwei Han
Guangzhi Hao
Song Han
Tingzhun Zhu
Yushu Dong
Ligang Chen
Xinyu Yang
Xiaoming Li
Hai Jin
Guobiao Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1537295

119 views

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Volumes

Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic pathways and BDNF expression

Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition

Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish

Climate change and the sustainable use of medicinal plants: a call for “new” research strategies

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

Hu-lu-su-pian ameliorates hepatic steatosis by regulating CIDEA expression in AKT-driven MASLD mice

Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage

Effects of dexmedetomidine-ropivacaine assisted combined spinal-epidural anesthesia on neutrophil-lymphocyte ratio and postoperative delirium in elderly patients with intertrochanteric femoral fracture

Ethanol extract of Polygonatum cyrtonema Hua mitigates non-alcoholic steatohepatitis in mice

The enigmatic SLC26A6 multifunctional anion transporter: recent advances in structure-function relationship, pathophysiological significance and novel pharmacological inhibitors

Population dynamics analysis of the interaction between tacrolimus and voriconazole in renal transplant recipients

Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells

Corrigendum: Polydatin ameliorates early brain injury after subarachnoid hemorrhage through up-regulating SIRT1 to suppress endoplasmic reticulum stress