Frontiers in Pharmacology

Original Research

Published on 11 Apr 2025

Evaluation of drug-drug interaction between Suraxavir Marboxil (GP681) and itraconazole, and assessment of the impact of gene polymorphism

Mai Han
Gang Cui
Yan Zhao
Xianbo Zuo
Xiaoxue Wang
Xin Zhang
Na Mi
Jiangli Jin
Chunyan Xiao
Jing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505557

826 views

Review

Published on 19 Mar 2025

Mitochondria and oxidative stress in epilepsy: advances in antioxidant therapy

Delphine Ji
Shanthini Mylvaganam
Prathyusha Ravi Chander
Mark Tarnopolsky
Keiran Murphy
Peter Carlen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505867

942 views

Correction

Published on 07 Mar 2025

Corrigendum: Novel chemical scaffolds to inhibit the neutral amino acid transporter B0AT1 (SLC6A19), a potential target to treat metabolic diseases

Aditya Yadav
Nishank Shah
Praveen Kumar Tiwari
Kiran Javed
Qi Cheng
Indrapal Singh Aidhen
Stefan Bröer

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485054

666 views

Original Research

Published on 05 Mar 2025

Allele and genotype frequencies of variants in P450 cytochromes, transports, and DNA repair enzymes in the Dominican Republic population

Elizabeth Pérez-Duval
Berniza Calderón
Marlen Izquierdo
José A. Herrera-Isidrón
Elizabeth Reyes-Reyes
Alejandro Herrera
Manuel Soto
Alba Beltré
Idania Rodeiro-Guerra

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494482

692 views

Case Report

Published on 27 Feb 2025

Re-challenging pralsetinib following recovery from pneumocystis jirovecii pneumonia in a lung cancer patient: a Case Report

Zhe Zhao
Longbin Pang
Surui Liu
Jie Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443609

979 views

Systematic Review

Published on 21 Feb 2025

Astragalus-containing Chinese herbal medicine used with Western medicine for lupus nephritis: a systematic review and meta-analysis of randomized controlled trials

Jinjiao Li
Mengyun Wu
Weiwei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1395844

1,587 views

Review

Published on 17 Feb 2025

Contribution and expression of renal drug transporters in renal cell carcinoma

Yawen Zuo
Tong Li
Shilei Yang
Xuyang Chen
Xufeng Tao
Deshi Dong
Fang Liu
Yanna Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466877

990 views

Original Research

Published on 17 Feb 2025

Comparison of the effects of perioperative fentanyl and morphine use on the short-term prognosis of patients with cardiac surgery in the ICU

Jingtao Zhong
Runqian Sui
Jie Zi
Anbiao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453835

1,458 views

Original Research

Published on 12 Feb 2025

Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes

Sadegh Faramarzi
Arianna Bassan
Kevin P. Cross
Xinning Yang
Glenn J. Myatt
Donna A. Volpe
Lidiya Stavitskaya

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451164

873 views

Original Research

Published on 10 Feb 2025

Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic pathways and BDNF expression

Hart Mann Alain Youbi Mambou
Simon Pale
Orelien Sylvain Mtopi Bopda
Vanessa Tita Jugha
Nji Seraphin Ombel Musa
Tambong Ako Ojongnkpot
Bertrand Yuwong Wanyu
Raymond Bess Bila
Rashed N. Herqash
Abdelaaty A. Shahat

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1301002

1,017 views

Original Research

Published on 05 Feb 2025

Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition

Sajida Parveen
Kashif ur Rehman Khan
Shahid Muhammad Iqbal
Hanan Y. Aati
Areej M. Al-taweel
Liaqat Hussain
Musaddique Hussain

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500085

947 views
1 citation

Original Research

Published on 05 Feb 2025

Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish

Xiaoqi Pan
Tianyu Liang
Han Feng
Weiying Liu
Qiaoxin Mou
Xiaoyu Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500527

679 views

Policy and Practice Reviews

Published on 03 Feb 2025

Climate change and the sustainable use of medicinal plants: a call for “new” research strategies

Olha Mykhailenko
Banaz Jalil
Lyndy J. McGaw
Javier Echeverría
Marce Takubessi
Michael Heinrich

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496792

3,099 views

Original Research

Published on 03 Feb 2025

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

Kohen Goble
Aarav Mehta
Damien Guilbaud
Jacob Fessler
Jingting Chen
William Nenad
Christina G. Ford
Oliver Cope
Darby Cheng
William Dennis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516621

1,100 views

Original Research

Published on 31 Jan 2025

Hu-lu-su-pian ameliorates hepatic steatosis by regulating CIDEA expression in AKT-driven MASLD mice

Rumeng Ren
Qi Wang
Dongjie Deng
Aoao Guo
Xin Chen
Yan Meng
Ying Fang
Guohua Zheng
Zhong Xu
Man Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1503247

1,072 views

Original Research

Published on 31 Jan 2025

Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice

Jiyao Zhao
Wei Shi
Yan Zheng
Junjie Wang
Muzhao Yuan
Yultuz Anwar
Yuxuan He
Haiping Ma
Jianjiang Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506401

1,051 views