Frontiers in Pharmacology

Systematic Review

Published on 12 Feb 2026

Cluster of differentiation 38 monoclonal antibody therapy in the treatment of multiple myeloma: a systematic review and meta-analysis

Yan-Jun Guo
Zhi-Zhong Tian
Xiao-Fen Zhang
Zhen-Jun Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1687718

439 views

Original Research

Published on 12 Feb 2026

Parabrachial calcitonin gene-related peptide neurons sex-specifically modulate behavior in anxiety assays during alcohol withdrawal

C. E. Van Doorn
J. B. Tyree
A. A. Jaramillo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1750956

388 views

Review

Published on 11 Feb 2026

Plant polysaccharides in neuroprotection: mechanistic insights across central nervous system disorders

Qiyue Yu
Hui Chen
Zhuofeng Qu
Jialin Qu
Yan Wang
Lina Liang
Shouyu Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1727705

407 views

Review

Published on 11 Feb 2026

Oleaceae plants: a source of metabolites with atheroprotective potential

Agnieszka Filipek
Edyta Czepielewska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721433

355 views

Review

Published on 11 Feb 2026

Research progress on mechanisms and applications of Chinese herbal pairs in treating hyperplasia of mammary gland

Lu Liu
Yuxuan Zhang
Wei Shen
Wanyu Li
Xudong Lei
Xiaoyan Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704606

471 views

Original Research

Published on 11 Feb 2026

Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

Martina Redl
Sabrina Weisenburger
Andreas Wasilewicz
Ulrike Grienke
Martin D. Lehner
Dirk Bredenbröker
Judith M. Rollinger

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1720314

431 views

Original Research

Published on 10 Feb 2026

Historical studies on the use of Rhubarb in Japan

Misato Ota
Toshiaki Makino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726521

649 views

Original Research

Published on 10 Feb 2026

Licochalcone B suppresses oxidative stress and apoptosis accompanied by upregulating Nrf2/HO-1 pathway to ameliorate diabetic nephropathy in mice

Shan Luo
Yake Lan
Ruoqi Zhang
Zhongqiu Luan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1737091

453 views

Case Report

Published on 10 Feb 2026

Clopidogrel-induced drug-induced hypersensitivity syndrome following percutaneous coronary intervention: a case report of therapeutic dilemma and management strategy

Sikun Wang
Jiang Zhou
Yuanhua Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695177

660 views

Review

Published on 10 Feb 2026

How do nanoparticle properties shape pharmacokinetics and pharmacodynamics? A mechanistic review

Esperanza Peralta-Cuevas
Nahomi Y. Degollado-Hernández
Iliana C. Martínez-Ortiz
Ashley J. Gutierrez-Onofre
Igor Garcia-Atutxa
Francisca Villanueva-Flores

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704814

822 views

Systematic Review

Published on 09 Feb 2026

Progress, critical challenges, and translational prospects of intranasal administration of botanical essential oils for the treatment of depression

Kexin Cheng
Hongyi Zhao
Kui He
Xiuwen Xia
Yi Wang
Shuyu Wang
Weihong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1748824

532 views

Review

Published on 09 Feb 2026

Incorporating patient-reported outcome measures into routine paediatric pharmacovigilance: opportunities for safety monitoring with practical use scenarios from paediatric oncology

Pedro Teodoro
Ricardo M. Fernandes
Inês Ribeiro
Renato Ferreira-da-Silva

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719963

406 views

Original Research

Published on 09 Feb 2026

Targeted lipidomics meets transcriptomics: how cinobufagin rewires fatty acid, sphingolipid, and glycerophospholipid metabolism to combat hepatoma cell growth

Wanjun Shao
Congying Yu
Rufei Xu
Xiaoqian Rong
Ailin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664915

381 views

Original Research

Published on 09 Feb 2026

Characterization and anti-inflammatory studies of supramolecular assemblies of chlorogenic acids with metal ions

Zhen-Min Zhang
Ru-Yue Zhang
Lian Zhu
Zi-Xuan Liu
Han-Xiu Deng
Jie-Fu Tang
Jia-Yu Zhang
Wei Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726226

333 views

Original Research

Published on 06 Feb 2026

Therapeutic potential of combination medicinal mushrooms (NevG) in ischemic stroke: correlating motor function, cognitive recovery, and hippocampal integrity in MCAO rats

Nur Athirah Azlan
Misya Afiqah Noor Tuah
Nik Nasihah Nik Ramli
Hussin Muhammad
Zolkapli Eshak
Liao Peng
Chen Bo
Yatinesh Kumari
Imran Jazuli
Che Mohd Nasril Che Mohd Nasir

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698883

784 views

Original Research

Published on 03 Feb 2026

Phytochemical profiling, antimicrobial, antibiofilm, and molecular docking of Farsetia aegyptia and Zilla spinosa from Saudi Arabia

Malek Besbes
Assia Hamdi
Mabrouk Horchani
Kaouther Majouli
Amal Dbeibia
Saoussen Jilani
Abeer Ayed Alshammari
Salwa Ahmed Lotfi
Khulood Fahad Alabbosh
Ramzi Hadj Lajimi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723207

798 views

Original Research

Published on 03 Feb 2026

Pharmacogenomic and in silico identification of isoform-selective AKT inhibitors from Pithecellobium dulce for precision cancer therapy

Gnanaprakash Jeyaraj
Bing Yang
Kuppusamy Sathishkumar
Santosh Chokkakula
Bader O. Almutairi
Weimim Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1744408

584 views

Review

Published on 03 Feb 2026

Targeting lipophagy and nuclear receptors in metabolic-associated fatty liver disease: insights from traditional Chinese medicine

Ting Yue
Nafei Huang
Ziming Zhao
Lili Yu
Xiaoming He
Xiao Yu
Yi Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1744069

425 views

Original Research

Published on 02 Feb 2026

In vitro exploration of drug-induced thrombotic microangiopathies: clues of diverse endothelial activation pathways respective to interferon-β1a, ciclosporin A, and gemcitabine exposure

Edouard Cubilier
Maxime Taghavi
Eric De Prez
Lucas Jacobs
Sébastien Sinaeve
Joëlle Nortier
Marie-Hélène Antoine

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719192

625 views

Original Research

Published on 30 Jan 2026

Molecular features of prenylated (iso)flavonoids from Fabaceae in relation to their potential NorA inhibition in Staphylococcus aureus

Marina Ika Irianti
Janniek Henrieke Ritsema
Jos Hageman
Jean-Paul Vincken
Carla Araya-Cloutier

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715533

558 views

Original Research

Published on 30 Jan 2026

Synthesis, characterization, and in silico and in vivo profiling of selective cyclo-oxygenase-2 inhibitors of indazole–indolinone derivatives with anti-inflammatory and analgesic potency

Sultan Ibrahim Alkubaysi
Mohammad Jaffar Sadiq Mantargi
Faisal Ateeq Almalki
Alaa Mohammad Alqahtani
Alaa Omar Baryyan
Saeed Mohammad Tayeb
Hussni Ahmad Muathen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723200

709 views

Review

Published on 30 Jan 2026

A comprehensive review on indigenous therapeutic approaches in kidney care using Ayush medicine

Niharika
Rabea Parveen
Bushra Parveen
Shahid Umar
Sayeed Ahmad

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588424

631 views

Original Research

Published on 30 Jan 2026

A new Jun amino-terminal kinase inhibitor, KRev-202, inhibits rat ischemic acute injury and the progression to renal fibrosis

David J. Nikolic-Paterson
Greg H. Tesch
Elyce Ozols
Kurt Jarnagin
Yoshi Satoh
David R. Webb
Elizabeth Squiers
Keren Grynberg
Frank Y. Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667221

426 views

Review

Published on 29 Jan 2026

Beneficial effects of berberine in the treatment of diabetes and its complications

Shanyao Liu
Jie Shen
Fanghui Xu
Lu Niu
Fengchan Wang
Guojing Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701513

657 views

4,175 Publications

volumes

Cluster of differentiation 38 monoclonal antibody therapy in the treatment of multiple myeloma: a systematic review and meta-analysis

Parabrachial calcitonin gene-related peptide neurons sex-specifically modulate behavior in anxiety assays during alcohol withdrawal

Plant polysaccharides in neuroprotection: mechanistic insights across central nervous system disorders

Oleaceae plants: a source of metabolites with atheroprotective potential

Research progress on mechanisms and applications of Chinese herbal pairs in treating hyperplasia of mammary gland

Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

Historical studies on the use of Rhubarb in Japan

Licochalcone B suppresses oxidative stress and apoptosis accompanied by upregulating Nrf2/HO-1 pathway to ameliorate diabetic nephropathy in mice

Clopidogrel-induced drug-induced hypersensitivity syndrome following percutaneous coronary intervention: a case report of therapeutic dilemma and management strategy

How do nanoparticle properties shape pharmacokinetics and pharmacodynamics? A mechanistic review

Progress, critical challenges, and translational prospects of intranasal administration of botanical essential oils for the treatment of depression

Incorporating patient-reported outcome measures into routine paediatric pharmacovigilance: opportunities for safety monitoring with practical use scenarios from paediatric oncology

Targeted lipidomics meets transcriptomics: how cinobufagin rewires fatty acid, sphingolipid, and glycerophospholipid metabolism to combat hepatoma cell growth

Characterization and anti-inflammatory studies of supramolecular assemblies of chlorogenic acids with metal ions

Therapeutic potential of combination medicinal mushrooms (NevG) in ischemic stroke: correlating motor function, cognitive recovery, and hippocampal integrity in MCAO rats

Phytochemical profiling, antimicrobial, antibiofilm, and molecular docking of Farsetia aegyptia and Zilla spinosa from Saudi Arabia

Pharmacogenomic and in silico identification of isoform-selective AKT inhibitors from Pithecellobium dulce for precision cancer therapy

Targeting lipophagy and nuclear receptors in metabolic-associated fatty liver disease: insights from traditional Chinese medicine

In vitro exploration of drug-induced thrombotic microangiopathies: clues of diverse endothelial activation pathways respective to interferon-β1a, ciclosporin A, and gemcitabine exposure

Molecular features of prenylated (iso)flavonoids from Fabaceae in relation to their potential NorA inhibition in Staphylococcus aureus

Synthesis, characterization, and in silico and in vivo profiling of selective cyclo-oxygenase-2 inhibitors of indazole–indolinone derivatives with anti-inflammatory and analgesic potency

A comprehensive review on indigenous therapeutic approaches in kidney care using Ayush medicine

A new Jun amino-terminal kinase inhibitor, KRev-202, inhibits rat ischemic acute injury and the progression to renal fibrosis

Beneficial effects of berberine in the treatment of diabetes and its complications