Frontiers in Pharmacology

Systematic Review

Accepted on 30 Dec 2025

Efficacy of Selected Dietary Supplements and Pharmacological Agents on Metabolic and Oxidative Stress Outcomes in Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD): A Bayesian Network Meta-analysis

Yunyi Yang
Xiaoli He
Yanming He
Jiayuan Cai
Tan Shufa
Jiawen You
Zheng Yao
Hongjie Yang

Frontiers in Pharmacology

Brief Research Report

Accepted on 30 Dec 2025

Very low enalapril and enalaprilat exposure via human milk: a case report from the ConcePTION project

Emily Jacobs
Michael Ceulemans
Nina Nauwelaerts
Siemon de Nys
Kathleen J Claes
Pieter Annaert
Kristel Van Calsteren
Anne Smits
Karel Allegaert
Martje Van Neste

Frontiers in Pharmacology

Mini Review

Accepted on 30 Dec 2025

Aloe-Emodin: From Pharmacological Mechanisms to Clinical Applications and Future Perspectives

Jin Xie
Junfeng Zhang
Xiaoyan Chen

Frontiers in Pharmacology

Review

Accepted on 30 Dec 2025

Pulmonary Hypertension: Etiology and Anti-Inflammatory Treatment Pathways of Natural Products

Liyang Li
Xing Huang
Maojun Cheng
Chengxun He
Changmao Dai
Fang Ding
Jia Xu
Feier Chen
Kaichen Zhang
Li Xueping

Frontiers in Pharmacology

Systematic Review

Accepted on 30 Dec 2025

Progress, Critical Challenges, and Translational Prospects of Intranasal Administration of Botanical Essential Oils for the Treatment of Depression

Kexin Cheng
Hongyi Zhao
Kui He
Xiuwen Xia
王祎
Shuyu Wang
WeiHong Li

Frontiers in Pharmacology

Review

Accepted on 30 Dec 2025

Natural terpenoids with therapeutic potential against pulmonary arterial hypertension

Kaijie Dang
Junru Zhang
Kexin Yu
Xinyu Liu
Yi Zhu
Xiuli Yang
XIAO LIU
Chuantao Zhang

Frontiers in Pharmacology

Original Research

Accepted on 30 Dec 2025

Ginsenoside Rk1 alleviates lipopolysaccharide (LPS)-induced cognitive impairment by modulating synaptic plasticity

Xuesong Zhang
Funan Ning
Biqun zhang
Jiaqi Ji
Junzuo Zheng
Xiaosong Hu
Zhiang Liu
Li Ding
Ping Wang
Zhou Lan

Frontiers in Pharmacology

Original Research

Accepted on 30 Dec 2025

Dual Inhibition of ERG11 and CDR2 in Drug-Resistant Candida albicans by Indian Phytochemicals: A Combined In Silico–In Vitro Aproach

Reena Rajkumari Baskaran
Akshay Kisan Mundhe

Frontiers in Pharmacology

Original Research

Accepted on 30 Dec 2025

Serum valeric acid stimulates lung epithelial cilia assembly and improves prognosis in patients with severe respiratory infections

Yabin Zhang
Yuqing Zhang
Lin Wang
Beibei Liu
Jia Jia Zheng
Jiabao Cao
Lixin Xie
Ning Shen
Jun Wang

Frontiers in Pharmacology

Original Research

Accepted on 30 Dec 2025

Real-World Safety Profile and Mechanistic Insights into Regorafenib-Induced Liver Failure: A Pharmacovigilance Study Integrated with Network Toxicology

Haonan Sun
Heng Gu
Pengkai Xu
Dong Jiang
Tian Pu
Jiangming Chen
Fubao Liu

Frontiers in Pharmacology

Review

Accepted on 30 Dec 2025

Pharmacological Advances in Multi-Targeted Strategies for Type 2 Diabetes Mellitus: A Systematic Perspective Based on Traditional Chinese Medicine

Yanli Zhao
Jiabao Liao
Panpan Pang
JingYuan Li
Suocai Su
Mengqiu Shao
Weibo Wen
Furong Xu

Frontiers in Pharmacology

Review

Accepted on 29 Dec 2025

Targeting Hippo-YAP/TAZ signaling pathway: An updated review demonstrating the therapeutic potential of key plant derived anticancer compounds

Deena Elsori
Pratibha Pandey
Kholoud Alshaikh
Ali Alkhathami
Mohd Saeed
Ajay Kumar
Fahad Khan

Frontiers in Pharmacology

Review

Accepted on 29 Dec 2025

Tribulus terrestris L.: A Medicinal Plant with Promising Therapeutic Potential for Skin Diseases

Xiao-Mu Wang
Xiao-Min Liu
Yan Zeng
Ke-Jing Zhu
Tian-Tian Shen
Fang Bian

Frontiers in Pharmacology

Systematic Review

Accepted on 29 Dec 2025

Traditional Herbal Medicine for Opioid-Induced Constipation in Patients with Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Su Hyeon Lee
Hayun Jin
Eun Hye Kim
Seong Woo Yoon

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Partially Hydrolyzed Formula with High sn-2 Palmitic Acid on Eosinophils and Outcomes in Preterm Infants: PRIOR Secondary Analysis

Jialu Zhuang
Ye Liu
Qiongyu Liu
Jiaan Wang
Songlin Liu
Jing Wu
Yanqing Shen
Xuemin Wang
Hui Zhang
Li Yuan

Frontiers in Pharmacology

Review

Accepted on 29 Dec 2025

Glutathione and Neurodegenerative Diseases: Immunopharmacological Implications

Ethan Knudsen
Jason Tadje
Carter Coggins
Vishwanath Venketaraman

Frontiers in Pharmacology

Review

Accepted on 29 Dec 2025

Incorporating Patient-Reported Outcome Measures into routine paediatric pharmacovigilance: opportunities for safety monitoring with practical use scenarios from paediatric oncology

Pedro Teodoro
Ricardo Fernandes
Inês Ribeiro
Renato Ferreira da Silva

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Licochalcone B suppresses oxidative stress and apoptosis accompanied by upregulating Nrf2/HO-1 pathway to ameliorate diabetic nephropathy in mice

Shan Luo
Yake Lan
Ruoqi Zhang
Zhongqiu Luan

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Setmelanotide-Mediated MC4R Activation Improves Hypothalamic Obesity via CaMKK2/AMPK Pathways

Junjie Peng
Yichao Ou
Mingfeng Zhou
Xingqin Wang
Xi'an Zhang
Hao Long
Guangsen Wu
Mengjie Che
Li Kai
Le Yang

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Parabrachial Calcitonin Gene-Related Peptide Neurons Sex-Specifically Modulate Behavior in Anxiety Assays During Alcohol Withdrawal

Catherine Elizabeth Van Doorn
Jordan Brooke Tyree
Anel Ariana Jaramillo

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Inflammatory and chemotactic signals of the brainstem solitary tract mediate the morphine exacerbation of impaired reflex chronotropism in septic rats

Mohamed Abdelnaby
Marwa Y Sallam
Mai M Helmy
Hanan M El-Gowelli
Mahmoud M El-Mas

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Disposition and effects of alpha-pyrrolidinoisohexanophenone (α-PHiP) in comparison with cocaine: an observational study

Georgina De La Rosa
Giorgia Iacobone
Esther Papaseit
Olga Hladun
Lourdes Poyatos
Dolly Andrea Caicedo
Martha Catalina Argote
Soraya Martín
Mireia Ventura
Alessandro Di Giorgi

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Dual blockade of DPP-4 and CXCL12/CXCR4 axes synergistically protects podocytes in lupus nephritis

Hui-miao Hu
Yong-chun Li
Yang-ming Zhang
Teng-yu Zhu
Wei-jing Yong
Yu-hui Gan
Chen Liu
Rui-ying Duan
Hong De Xu
Zhanzheng Zhao

Frontiers in Pharmacology

Systematic Review

Accepted on 29 Dec 2025

The Effect of Plant Active Substances on Cognitive Function in Healthy Older Adults: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Xueyan Feng
Shuangbo Fan
Fengqin Wei

Frontiers in Pharmacology

4,177 Publications

volumes

Efficacy of Selected Dietary Supplements and Pharmacological Agents on Metabolic and Oxidative Stress Outcomes in Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD): A Bayesian Network Meta-analysis

Very low enalapril and enalaprilat exposure via human milk: a case report from the ConcePTION project

Aloe-Emodin: From Pharmacological Mechanisms to Clinical Applications and Future Perspectives

Pulmonary Hypertension: Etiology and Anti-Inflammatory Treatment Pathways of Natural Products

Progress, Critical Challenges, and Translational Prospects of Intranasal Administration of Botanical Essential Oils for the Treatment of Depression

Natural terpenoids with therapeutic potential against pulmonary arterial hypertension

Ginsenoside Rk1 alleviates lipopolysaccharide (LPS)-induced cognitive impairment by modulating synaptic plasticity

Dual Inhibition of ERG11 and CDR2 in Drug-Resistant Candida albicans by Indian Phytochemicals: A Combined In Silico–In Vitro Aproach

Serum valeric acid stimulates lung epithelial cilia assembly and improves prognosis in patients with severe respiratory infections

Real-World Safety Profile and Mechanistic Insights into Regorafenib-Induced Liver Failure: A Pharmacovigilance Study Integrated with Network Toxicology

Pharmacological Advances in Multi-Targeted Strategies for Type 2 Diabetes Mellitus: A Systematic Perspective Based on Traditional Chinese Medicine

Targeting Hippo-YAP/TAZ signaling pathway: An updated review demonstrating the therapeutic potential of key plant derived anticancer compounds

Tribulus terrestris L.: A Medicinal Plant with Promising Therapeutic Potential for Skin Diseases

Traditional Herbal Medicine for Opioid-Induced Constipation in Patients with Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Partially Hydrolyzed Formula with High sn-2 Palmitic Acid on Eosinophils and Outcomes in Preterm Infants: PRIOR Secondary Analysis

Glutathione and Neurodegenerative Diseases: Immunopharmacological Implications

Incorporating Patient-Reported Outcome Measures into routine paediatric pharmacovigilance: opportunities for safety monitoring with practical use scenarios from paediatric oncology

Licochalcone B suppresses oxidative stress and apoptosis accompanied by upregulating Nrf2/HO-1 pathway to ameliorate diabetic nephropathy in mice

Setmelanotide-Mediated MC4R Activation Improves Hypothalamic Obesity via CaMKK2/AMPK Pathways

Parabrachial Calcitonin Gene-Related Peptide Neurons Sex-Specifically Modulate Behavior in Anxiety Assays During Alcohol Withdrawal

Inflammatory and chemotactic signals of the brainstem solitary tract mediate the morphine exacerbation of impaired reflex chronotropism in septic rats

Disposition and effects of alpha-pyrrolidinoisohexanophenone (α-PHiP) in comparison with cocaine: an observational study

Dual blockade of DPP-4 and CXCL12/CXCR4 axes synergistically protects podocytes in lupus nephritis

The Effect of Plant Active Substances on Cognitive Function in Healthy Older Adults: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials