Frontiers in Physiology | Computational Physiology and Medicine

Original Research

Published on 12 Feb 2026

Development and validation of a high-performance clinical predictive model for early identification of non-alcoholic fatty liver disease

in Computational Physiology and Medicine

Tong Liang
Junli Ren

Frontiers in Physiology

doi 10.3389/fphys.2026.1689882

286 views

Original Research

Accepted on 06 Feb 2026

CRC-Former: Frequency-Domain Adaptive Swin-Transformer for Colorectal Cancer Histopathology Classification

in Computational Physiology and Medicine

Lei Chen
Chenguang Li
Fanqi Meng
Jiandong Tai
Kun Wang

Frontiers in Physiology

119 views

Original Research

Published on 05 Feb 2026

End-to-end non-invasive ECG signal generation from PPG signal: a self-supervised learning approach

in Computational Physiology and Medicine

Murat Yalcin
Marc Erich Latoschik

Frontiers in Physiology

doi 10.3389/fphys.2026.1694995

905 views

Original Research

Published on 03 Feb 2026

Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion

in Computational Physiology and Medicine

Daan Imholz
Sue A. Braithwaite
Paul Blankman
Eline Oppersma
Frans H. C. de Jongh
Linda M. de Heer
Bart Luijk
Wolfgang F. F. A. Buhre
Dirk W. Donker
Lex M. van Loon

Frontiers in Physiology

doi 10.3389/fphys.2025.1724724

879 views

Original Research

Published on 27 Jan 2026

Predicting the growth of asymptomatic small abdominal aortic aneurysms (AAA) based on deep learning

in Computational Physiology and Medicine

Jiaxin Cheng
Zhiqiang Zhang
Yasong Wang
Yu Sun
Nan Wang
Xiaozeng Wang
Sihan Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1704428

662 views

Original Research

Published on 23 Jan 2026

Non-contact seismocardiogram measurement and HRV analysis using cardiac beamforming with FMCW radar

in Computational Physiology and Medicine

Guang Yu
Chenxi Yang
Haobo Li
Chaochao Wang
Xianchao Zhang
Jianqing Li
Chengyu Liu

Frontiers in Physiology

doi 10.3389/fphys.2025.1733573

744 views

Original Research

Published on 22 Jan 2026

K+ channel blockade limits AF and suppresses phase 3 EADs by slowing repolarization in an electromechanical cell computational model

in Computational Physiology and Medicine

Fazeelat Mazhar
Stefano Severi
Chiara Bartolucci

Frontiers in Physiology

doi 10.3389/fphys.2025.1704051

887 views

Original Research

Accepted on 20 Jan 2026

Explainable Deep-Learning Models to Predict Diaphragmatic Dysfunction and Cognitive Stress in ICU Patients Under Mechanical Ventilation

in Computational Physiology and Medicine

YONGHUA WANG
YulingBai bai
GE JIN

Frontiers in Physiology

108 views

Original Research

Published on 15 Jan 2026

Integration of PCG spectrogram texture and deep features for the diagnosis of heart failure with preserved ejection fraction using heterogeneous stacking ensemble learning

in Computational Physiology and Medicine

Yineng Zheng
Jian Qin
Fajin Lv
Xia Li
Xingming Guo

Frontiers in Physiology

doi 10.3389/fphys.2025.1694781

769 views

Original Research

Published on 12 Jan 2026

Hemodynamic consequences of pressure-flow curve gradient variations in continuous-flow ventricular assist devices

in Computational Physiology and Medicine

Yuzhuo Yang
Zhenyu Wang
Zipeng Xie
Shunzhou Yu
Liang Zou

Frontiers in Physiology

doi 10.3389/fphys.2025.1730883

799 views

Original Research

Published on 08 Jan 2026

Lobe-wise cognitive load detection using empirical Fourier decomposition and optimized machine learning

in Computational Physiology and Medicine

Kunamneni Chervitha
Lakhan Dev Sharma

Frontiers in Physiology

doi 10.3389/fphys.2025.1700756

567 views

Original Research

Published on 05 Jan 2026

Profile-aided distillation framework for personalized sleep analysis with compact models using LLM-guided synthetic data

in Computational Physiology and Medicine

Huimin Zheng
Xingxing Ai
Xueyan Liu
Xiaofen Xing
Xiangmin Xu

Frontiers in Physiology

doi 10.3389/fphys.2025.1678364

1,294 views

Mini Review

Published on 05 Jan 2026

A new paradigm in postoperative colorectal cancer surveillance: integrating advanced imaging and multi-omics

in Computational Physiology and Medicine

Dongxue Yu
Jiandong Tai

Frontiers in Physiology

doi 10.3389/fphys.2025.1758385

919 views

Original Research

Published on 02 Jan 2026

Physiological framework for non-invasive detection and objective nociception activity in communicative patients: a pilot case study

in Computational Physiology and Medicine

Ghada Ben Othman
Dana Copot
Bora Ayvaz
Robin De Keyser
Clara M. Ionescu

Frontiers in Physiology

doi 10.3389/fphys.2025.1704303

916 views

Original Research

Published on 18 Dec 2025

Mechanically-foldable axial flow blood pump: response-surface-based structural optimization and hemolytic performance evaluation

in Computational Physiology and Medicine

Tairan Ji
Teng Jing
Jianan Cheng

Frontiers in Physiology

doi 10.3389/fphys.2025.1632333

1,201 views

Original Research

Published on 10 Dec 2025

The critical role of inflammation in osteoporosis prediction unveiled by a machine learning framework integrating multi-source data

in Computational Physiology and Medicine

Bo Liu
Hongli Chang
Peipei Li
Hongguang Chang
Xuenan Wang
Wubing He

Frontiers in Physiology

doi 10.3389/fphys.2025.1729997

1,471 views

Original Research

Published on 28 Nov 2025

A model to simulate human cardio-respiratory responses to airway obstruction

in Computational Physiology and Medicine

Xin Jin
Varghese Kurian
Kathy L. Ryan
Anders Wallqvist
Jaques Reifman
Sridevi Nagaraja

Frontiers in Physiology

doi 10.3389/fphys.2025.1699315

1,488 views

Original Research

Published on 26 Nov 2025

Impact of vascular density on pancreatic islet viability: a computational study

in Computational Physiology and Medicine

Gerardo J. Félix-Martínez
Lizbeth de la Cruz
Daniel Whisman
J. Rafael Godínez-Fernández

Frontiers in Physiology

doi 10.3389/fphys.2025.1707026

1,356 views

Technology and Code

Published on 26 Nov 2025

Snoring sound classification in patients with cerebrovascular stenosis based on an improved ConvNeXt model

in Computational Physiology and Medicine

Caijian Hua
Zhihui Liu
Liuying Li
Xia Zhou
Caorong Xiang

Frontiers in Physiology

doi 10.3389/fphys.2025.1661258

1,154 views

Original Research

Published on 25 Nov 2025

Deep learning approach for objective differentiation of kidney deficiency syndrome in reproductive age females: a tongue-face fusion model

in Computational Physiology and Medicine

Kaiwei Li
Zehong Qiu
Jialing Li
Feilin Deng
Kun Zou
Yihua Xu
Chen Huang
Ran Wang
Zhaoji Yu
Yuzhi Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1701545

1,220 views

Original Research

Published on 18 Nov 2025

The microbiological and metabolic traits associated with pT3 colorectal cancer metastasis to lymph nodes

in Computational Physiology and Medicine

Lei Chen
Yiwen Zhang
Yilin Wang
Dianbo Cao
Jiandong Tai
Kaiyue Gao

Frontiers in Physiology

doi 10.3389/fphys.2025.1724429

973 views

Original Research

Published on 17 Nov 2025

An EEG-based machine learning framework for diagnosing acute sleep deprivation

in Computational Physiology and Medicine

Daya Kumar
Apurva Narayan
Saptharishi Lalgudi Ganesan

Frontiers in Physiology

doi 10.3389/fphys.2025.1668129

1,990 views

Original Research

Published on 17 Nov 2025

Machine learning model for detecting masked hypertension in young adults

in Computational Physiology and Medicine

Brendyn Miller
Samuel J. Coeyman
Annemarie Wentzel
Carina M. C. Mels
William J. Richardson

Frontiers in Physiology

doi 10.3389/fphys.2025.1684693

1,538 views

Original Research

Published on 13 Nov 2025

The establishment and biomechanical analysis of finite element model for halo-pelvic traction in scoliosis correction

in Computational Physiology and Medicine

Wanzhong Yang
Wei Guo
Jie Yang
Honglai Zhang
Zemin Wang
Shiyong Wang
Jianqun Zhang
Xiaoyin Liu
Rong Ma
Zhaohui Ge

Frontiers in Physiology

doi 10.3389/fphys.2025.1670376

1,603 views

1,170 articles

articles

Development and validation of a high-performance clinical predictive model for early identification of non-alcoholic fatty liver disease

CRC-Former: Frequency-Domain Adaptive Swin-Transformer for Colorectal Cancer Histopathology Classification

End-to-end non-invasive ECG signal generation from PPG signal: a self-supervised learning approach

Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion

Predicting the growth of asymptomatic small abdominal aortic aneurysms (AAA) based on deep learning

Non-contact seismocardiogram measurement and HRV analysis using cardiac beamforming with FMCW radar

K+ channel blockade limits AF and suppresses phase 3 EADs by slowing repolarization in an electromechanical cell computational model

Explainable Deep-Learning Models to Predict Diaphragmatic Dysfunction and Cognitive Stress in ICU Patients Under Mechanical Ventilation

Integration of PCG spectrogram texture and deep features for the diagnosis of heart failure with preserved ejection fraction using heterogeneous stacking ensemble learning

Hemodynamic consequences of pressure-flow curve gradient variations in continuous-flow ventricular assist devices

Lobe-wise cognitive load detection using empirical Fourier decomposition and optimized machine learning

Profile-aided distillation framework for personalized sleep analysis with compact models using LLM-guided synthetic data

A new paradigm in postoperative colorectal cancer surveillance: integrating advanced imaging and multi-omics

Physiological framework for non-invasive detection and objective nociception activity in communicative patients: a pilot case study

Mechanically-foldable axial flow blood pump: response-surface-based structural optimization and hemolytic performance evaluation

The critical role of inflammation in osteoporosis prediction unveiled by a machine learning framework integrating multi-source data

A model to simulate human cardio-respiratory responses to airway obstruction

Impact of vascular density on pancreatic islet viability: a computational study

Snoring sound classification in patients with cerebrovascular stenosis based on an improved ConvNeXt model

Deep learning approach for objective differentiation of kidney deficiency syndrome in reproductive age females: a tongue-face fusion model

The microbiological and metabolic traits associated with pT3 colorectal cancer metastasis to lymph nodes

An EEG-based machine learning framework for diagnosing acute sleep deprivation

Machine learning model for detecting masked hypertension in young adults

The establishment and biomechanical analysis of finite element model for halo-pelvic traction in scoliosis correction