Frontiers in Physiology | Gastrointestinal Sciences

Original Research

Published on 26 Mar 2019

Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules

in Gastrointestinal Sciences

Cristiane Assunção da Costa Cunha Mafra
Roseane Carvalho Vasconcelos
Caroline Addison Carvalho Xavier de Medeiros
Renata Ferreira de Carvalho Leitão
Gerly Anne de Castro Brito
Deiziane Viana da Silva Costa
Gerlane Coelho Bernardo Guerra
Raimundo Fernandes de Araújo
Aldo Cunha Medeiros
Aurigena Antunes de Araújo

Frontiers in Physiology

doi 10.3389/fphys.2019.00327

5,379 views
27 citations

Original Research

Published on 20 Mar 2019

Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage

in Gastrointestinal Sciences

Wuping Yang
Lijian Shao
Sihong Zhu
Huan Li
Xinxin Zhang
Congcong Ding
Xincheng Wu
Rui Xu
Mengzhen Yue
Jiahui Tang

Frontiers in Physiology

doi 10.3389/fphys.2019.00228

4,520 views
16 citations

Mini Review

Published on 14 Mar 2019

Intestinal Bacteria Interplay With Bile and Cholesterol Metabolism: Implications on Host Physiology

in Gastrointestinal Sciences

Natalia Molinero
Lorena Ruiz
Borja Sánchez
Abelardo Margolles
Susana Delgado

Frontiers in Physiology

doi 10.3389/fphys.2019.00185

37,964 views
223 citations

Original Research

Published on 26 Feb 2019

MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)

in Gastrointestinal Sciences

Ce Li
Susan Morvaridi
Gloria Lam
Chintan Chheda
Yoshiko Kamata
Makoto Katsumata
Mouad Edderkaoui
Xiaopu Yuan
Nicholas Nissen
Stephen J. Pandol

Frontiers in Physiology

doi 10.3389/fphys.2019.00147

6,014 views
21 citations

Original Research

Published on 12 Feb 2019

LSEC Fenestrae Are Preserved Despite Pro-inflammatory Phenotype of Liver Sinusoidal Endothelial Cells in Mice on High Fat Diet

in Gastrointestinal Sciences

Edyta Kus
Patrycja Kaczara
Izabela Czyzynska-Cichon
Karolina Szafranska
Bartlomiej Zapotoczny
Agnieszka Kij
Agnieszka Sowinska
Jerzy Kotlinowski
Lukasz Mateuszuk
Elzbieta Czarnowska

Frontiers in Physiology

doi 10.3389/fphys.2019.00006

12,718 views
59 citations

Original Research

Published on 08 Feb 2019

A Combined Metabolomic and Proteomic Study Revealed the Difference in Metabolite and Protein Expression Profiles in Ruminal Tissue From Goats Fed Hay or High-Grain Diets

in Gastrointestinal Sciences

Changzheng Guo
Daming Sun
Xinfeng Wang
Shengyong Mao

Frontiers in Physiology

doi 10.3389/fphys.2019.00066

6,313 views
23 citations

Original Research

Published on 08 Feb 2019

Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis

in Gastrointestinal Sciences

Peiyuan Li
Jiajun Lei
Guangsheng Hu
Xuanmin Chen
Zhifeng Liu
Jing Yang

Frontiers in Physiology

doi 10.3389/fphys.2019.00028

5,250 views
43 citations

Clinical Trial

Published on 05 Feb 2019

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity

in Gastrointestinal Sciences

Maria Carlota Dao
Nataliya Sokolovska
Rémi Brazeilles
Séverine Affeldt
Véronique Pelloux
Edi Prifti
Julien Chilloux
Eric O. Verger
Brandon D. Kayser
Judith Aron-Wisnewsky

Frontiers in Physiology

doi 10.3389/fphys.2018.01958

12,189 views
39 citations

Original Research

Published on 04 Feb 2019

Association Between Single Nucleotide Polymorphisms in PPARA and EPAS1 Genes and High-Altitude Appetite Loss in Chinese Young Men

in Gastrointestinal Sciences

Wenxu Pan
Chuan Liu
Jihang Zhang
Xubin Gao
Shiyong Yu
Hu Tan
Jie Yu
Dehui Qian
Jiabei Li
Shizhu Bian

Frontiers in Physiology

doi 10.3389/fphys.2019.00059

5,013 views
15 citations

Original Research

Published on 24 Jan 2019

Methylation in MIRLET7A3 Gene Induces the Expression of IGF-II and Its mRNA Binding Proteins IGF2BP-2 and 3 in Hepatocellular Carcinoma

in Gastrointestinal Sciences

Amr A. Waly
Nada El-Ekiaby
Reem A. Assal
Mohamed M. Abdelrahman
Karim A. Hosny
Hend M. El Tayebi
Gamal Esmat
Kai Breuhahn
Ahmed I. Abdelaziz

Frontiers in Physiology

doi 10.3389/fphys.2018.01918

5,457 views
21 citations

Review

Published on 23 Jan 2019

Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

in Gastrointestinal Sciences

Ajaz A. Bhat
Srijayaprakash Uppada
Iman W. Achkar
Sheema Hashem
Santosh K. Yadav
Muralitharan Shanmugakonar
Hamda A. Al-Naemi
Mohammad Haris
Shahab Uddin

Frontiers in Physiology

doi 10.3389/fphys.2018.01942

82,867 views
372 citations

General Commentary

Published on 22 Jan 2019

Commentary: Blood-Derived microRNAs for Pancreatic Cancer Diagnosis: A Narrative Review and Meta-Analysis

in Gastrointestinal Sciences

Rama Jayaraj
Chellan Kumarasamy
Shanthi Sabarimurugan
Siddhartha Baxi

Frontiers in Physiology

doi 10.3389/fphys.2018.01896

2,255 views
11 citations

Original Research

Published on 18 Jan 2019

Dietary Supplementation With High Fiber Alleviates Oxidative Stress and Inflammatory Responses Caused by Severe Sepsis in Mice Without Altering Microbiome Diversity

in Gastrointestinal Sciences

Yuanyuan Zhang
Aili Dong
Keliang Xie
Yonghao Yu

Frontiers in Physiology

doi 10.3389/fphys.2018.01929

7,342 views
25 citations

Original Research

Published on 17 Jan 2019

Intestinal Morphologic and Microbiota Responses to Dietary Bacillus spp. in a Broiler Chicken Model

in Gastrointestinal Sciences

Cheng-liang Li
Jing Wang
Hai-jun Zhang
Shu-geng Wu
Qian-ru Hui
Cheng-bo Yang
Re-jun Fang
Guang-hai Qi

Frontiers in Physiology

doi 10.3389/fphys.2018.01968

11,711 views
101 citations

Mini Review

Published on 15 Jan 2019

Investigating Gut Permeability in Animal Models of Disease

in Gastrointestinal Sciences

Marianela González-González
Camilo Díaz-Zepeda
Johana Eyzaguirre-Velásquez
Camila González-Arancibia
Javier A. Bravo
Marcela Julio-Pieper

Frontiers in Physiology

doi 10.3389/fphys.2018.01962

26,190 views
61 citations

Original Research

Published on 15 Jan 2019

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

in Gastrointestinal Sciences

Xiaoying Zhang
Tao Jin
Na Shi
Linbo Yao
Xinmin Yang
Chenxia Han
Li Wen
Dan Du
Peter Szatmary
Rajarshi Mukherjee

Frontiers in Physiology

doi 10.3389/fphys.2018.01922

13,006 views
38 citations

Review

Published on 20 Dec 2018

Cystic Fibrosis of the Pancreas: The Role of CFTR Channel in the Regulation of Intracellular Ca2+ Signaling and Mitochondrial Function in the Exocrine Pancreas

in Gastrointestinal Sciences

Tamara Madácsy
Petra Pallagi
Jozsef Maleth

Frontiers in Physiology

doi 10.3389/fphys.2018.01585

42,349 views
57 citations

Review

Published on 18 Dec 2018

Intestinal Microbiota Modulation in Obesity-Related Non-alcoholic Fatty Liver Disease

in Gastrointestinal Sciences

David Porras
Esther Nistal
Susana Martínez-Flórez
Javier González-Gallego
María Victoria García-Mediavilla
Sonia Sánchez-Campos

Frontiers in Physiology

doi 10.3389/fphys.2018.01813

14,268 views
89 citations

Original Research

Published on 17 Dec 2018

Arcuate Nucleus Orexin-A Signaling Alleviates Cisplatin-Induced Nausea and Vomiting Through the Paraventricular Nucleus of the Hypothalamus in Rats

in Gastrointestinal Sciences

Feifei Guo
Shengli Gao
Luo Xu
Xiangrong Sun
Nana Zhang
Yanling Gong
Xiao Luan

Frontiers in Physiology

doi 10.3389/fphys.2018.01811

3,855 views
10 citations

Original Research

Published on 12 Dec 2018

Dynamic Metabolic Zonation of the Hepatic Glucose Metabolism Is Accomplished by Sinusoidal Plasma Gradients of Nutrients and Hormones

in Gastrointestinal Sciences

Nikolaus Berndt
Hermann-Georg Holzhütter

Frontiers in Physiology

doi 10.3389/fphys.2018.01786

8,301 views
33 citations

Original Research

Published on 04 Dec 2018

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice

in Gastrointestinal Sciences

Han Zheng
Yang You
Meiyun Hua
Pengfei Wu
Yu Liu
Zishuo Chen
Li Zhang
Haoche Wei
Yan Li
Mei Luo

Frontiers in Physiology

doi 10.3389/fphys.2018.01671

26,026 views
51 citations

Data Report

Published on 27 Nov 2018

Complete Genome Sequencing of Lactobacillus plantarum ZLP001, a Potential Probiotic That Enhances Intestinal Epithelial Barrier Function and Defense Against Pathogens in Pigs

in Gastrointestinal Sciences

Wei Zhang
Haifeng Ji
Dongyan Zhang
Hui Liu
Sixin Wang
Jing Wang
Yamin Wang

Frontiers in Physiology

doi 10.3389/fphys.2018.01689

11,435 views
60 citations

Systematic Review

Published on 19 Nov 2018

PPIs Are Not Responsible for Elevating Cardiovascular Risk in Patients on Clopidogrel—A Systematic Review and Meta-Analysis

in Gastrointestinal Sciences

Alexandra Demcsák
Tamás Lantos
Emese Réka Bálint
Petra Hartmann
Áron Vincze
Judit Bajor
László Czopf
Hussain Alizadeh
Zoltán Gyöngyi
Katalin Márta

Frontiers in Physiology

doi 10.3389/fphys.2018.01550

15,688 views
27 citations

Review

Published on 12 Nov 2018

Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors

in Gastrointestinal Sciences

Sarah C. Pearce
Heidi G. Coia
J. P. Karl
Ida G. Pantoja-Feliciano
Nicholas C. Zachos
Kenneth Racicot

Frontiers in Physiology

doi 10.3389/fphys.2018.01584

38,761 views
145 citations

573 articles

articles

Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules

Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage

Intestinal Bacteria Interplay With Bile and Cholesterol Metabolism: Implications on Host Physiology

MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)

LSEC Fenestrae Are Preserved Despite Pro-inflammatory Phenotype of Liver Sinusoidal Endothelial Cells in Mice on High Fat Diet

A Combined Metabolomic and Proteomic Study Revealed the Difference in Metabolite and Protein Expression Profiles in Ruminal Tissue From Goats Fed Hay or High-Grain Diets

Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity

Association Between Single Nucleotide Polymorphisms in PPARA and EPAS1 Genes and High-Altitude Appetite Loss in Chinese Young Men

Methylation in MIRLET7A3 Gene Induces the Expression of IGF-II and Its mRNA Binding Proteins IGF2BP-2 and 3 in Hepatocellular Carcinoma

Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

Commentary: Blood-Derived microRNAs for Pancreatic Cancer Diagnosis: A Narrative Review and Meta-Analysis

Dietary Supplementation With High Fiber Alleviates Oxidative Stress and Inflammatory Responses Caused by Severe Sepsis in Mice Without Altering Microbiome Diversity

Intestinal Morphologic and Microbiota Responses to Dietary Bacillus spp. in a Broiler Chicken Model

Investigating Gut Permeability in Animal Models of Disease

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

Cystic Fibrosis of the Pancreas: The Role of CFTR Channel in the Regulation of Intracellular Ca2+ Signaling and Mitochondrial Function in the Exocrine Pancreas

Intestinal Microbiota Modulation in Obesity-Related Non-alcoholic Fatty Liver Disease

Arcuate Nucleus Orexin-A Signaling Alleviates Cisplatin-Induced Nausea and Vomiting Through the Paraventricular Nucleus of the Hypothalamus in Rats

Dynamic Metabolic Zonation of the Hepatic Glucose Metabolism Is Accomplished by Sinusoidal Plasma Gradients of Nutrients and Hormones

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice

Complete Genome Sequencing of Lactobacillus plantarum ZLP001, a Potential Probiotic That Enhances Intestinal Epithelial Barrier Function and Defense Against Pathogens in Pigs

PPIs Are Not Responsible for Elevating Cardiovascular Risk in Patients on Clopidogrel—A Systematic Review and Meta-Analysis

Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors