Frontiers in Physiology | Gastrointestinal Sciences

Original Research

Published on 07 Jul 2015

A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes

in Gastrointestinal Sciences

Daniel J Cook
Biswanath Patra
Lakshmi Kuttippurathu
Jan B Hoek
Rajanikanth Vadigepalli

Frontiers in Physiology

doi 10.3389/fphys.2015.00189

5,020 views
8 citations

Mini Review

Published on 23 Jun 2015

Human liver myofibroblasts during development and diseases with a focus on portal (myo)fibroblasts

in Gastrointestinal Sciences

Sébastien Lepreux
Alexis Desmoulière

Frontiers in Physiology

doi 10.3389/fphys.2015.00173

10,309 views
54 citations

Review

Published on 16 Jun 2015

Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure

in Gastrointestinal Sciences

Hong-Lei Weng
Xiaobo Cai
Xiaodong Yuan
Roman Liebe
Steven Dooley
Hai Li
Tai-Ling Wang

Frontiers in Physiology

doi 10.3389/fphys.2015.00178

17,191 views
49 citations

Original Research

Published on 22 May 2015

Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production

in Gastrointestinal Sciences

Milan Fiala
Ramesh Halder
Anasheh Almasi
Bien Sagong
Jessica Leung
Anahid Jewett

Frontiers in Physiology

doi 10.3389/fphys.2015.00129

8,794 views
53 citations

Mini Review

Published on 15 May 2015

What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?

in Gastrointestinal Sciences

Stephen J. Pandol
Mouad Edderkaoui

Frontiers in Physiology

doi 10.3389/fphys.2015.00125

7,755 views
15 citations

Review

Published on 06 May 2015

The hop constituent xanthohumol exhibits hepatoprotective effects and inhibits the activation of hepatic stellate cells at different levels

in Gastrointestinal Sciences

Ralf Weiskirchen
Abdo Mahli
Sabine Weiskirchen
Claus Hellerbrand

Frontiers in Physiology

doi 10.3389/fphys.2015.00140

21,089 views
53 citations

Original Research

Published on 24 Mar 2015

Chemical coding and chemosensory properties of cholinergic brush cells in the mouse gastrointestinal and biliary tract

in Gastrointestinal Sciences

Burkhard Schütz
Innokentij Jurastow
Sandra Bader
Cornelia Ringer
Jakob von Engelhardt
Vladimir Chubanov
Thomas Gudermann
Martin Diener
Wolfgang Kummer
Gabriela Krasteva-Christ

Frontiers in Physiology

doi 10.3389/fphys.2015.00087

12,812 views
121 citations

Original Research

Published on 27 Feb 2015

High fat feeding affects the number of GPR120 cells and enteroendocrine cells in the mouse stomach

in Gastrointestinal Sciences

Patricia Widmayer
Hannah Goldschmid
Helena Henkel
Markus Küper
Alfred Königsrainer
Heinz Breer

Frontiers in Physiology

doi 10.3389/fphys.2015.00053

7,727 views
24 citations

Mini Review

Published on 16 Dec 2014

Allosteric modulation of Ras and the PI3K/AKT/mTOR pathway: emerging therapeutic opportunities

in Gastrointestinal Sciences

Paul A. Hubbard
Colleen L. Moody
Ramachandran Murali

Frontiers in Physiology

doi 10.3389/fphys.2014.00478

14,206 views
47 citations

Editorial

Published on 10 Dec 2014

Risk factors for pancreatic cancer: underlying mechanisms and potential targets

in Gastrointestinal Sciences

Mouad Edderkaoui
Guido Eibl

Frontiers in Physiology

doi 10.3389/fphys.2014.00490

4,993 views
6 citations

Review

Published on 04 Dec 2014

Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models

in Gastrointestinal Sciences

Brian T. DeCant
Daniel R. Principe
Carmen Guerra
Marina Pasca di Magliano
Paul J. Grippo

Frontiers in Physiology

doi 10.3389/fphys.2014.00464

11,302 views
21 citations

Mini Review

Published on 07 Nov 2014

Diabetes, pancreatic cancer, and metformin therapy

in Gastrointestinal Sciences

Jun Gong
Lori A. Robbins
Aurelia Lugea
Richard T. Waldron
Christie Y. Jeon
Stephen J. Pandol

Frontiers in Physiology

doi 10.3389/fphys.2014.00426

25,975 views
55 citations

Original Research

Published on 03 Nov 2014

Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC- pathway and modulated by endogenous H2S

in Gastrointestinal Sciences

Vanitha Bala
Senthilkumar Rajagopal
Divya P Kumar
Ancy D Nalli
Sunila Mahavadi
Arun J Sanyal
John R Grider
Karnam Murthy

Frontiers in Physiology

doi 10.3389/fphys.2014.00420

16,343 views
106 citations

Review

Published on 15 Oct 2014

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts

in Gastrointestinal Sciences

Marco Falasca
Tania Maffucci

Frontiers in Physiology

doi 10.3389/fphys.2014.00391

6,326 views
11 citations

Mini Review

Published on 23 Sep 2014

Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells

in Gastrointestinal Sciences

Enrique Rozengurt

Frontiers in Physiology

doi 10.3389/fphys.2014.00357

15,165 views
59 citations

Editorial

Published on 11 Aug 2014

Recent advances in pancreatology

in Gastrointestinal Sciences

Atsushi Masamune

Frontiers in Physiology

doi 10.3389/fphys.2014.00300

3,942 views

Mini Review

Published on 25 Jun 2014

Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin

in Gastrointestinal Sciences

Guisheng Zhou
Jim Sinnett-Smith
Shi-He Liu
Juehua Yu
James Wu
Robbi Sanchez
Stephen J. Pandol
Ravinder Abrol
John Nemunaitis
Enrique Rozengurt

Frontiers in Physiology

doi 10.3389/fphys.2014.00226

8,732 views
20 citations

Original Research

Published on 16 Apr 2014

Receptors for short-chain fatty acids in brush cells at the “gastric groove”

in Gastrointestinal Sciences

Julia Anna-Maria Eberle
Patricia Widmayer
Heinz Breer

Frontiers in Physiology

doi 10.3389/fphys.2014.00152

7,461 views
32 citations

Review

Published on 09 Apr 2014

Role of pancreatic stellate cells in chemoresistance in pancreatic cancer

in Gastrointestinal Sciences

Joshua A. McCarroll
Stephanie Naim
George Sharbeen
Nelson Russia
Julia Lee
Maria Kavallaris
David Goldstein
Phoebe A. Phillips

Frontiers in Physiology

doi 10.3389/fphys.2014.00141

19,603 views
140 citations

Review

Published on 03 Mar 2014

Genetic determinants and potential therapeutic targets for pancreatic adenocarcinoma

in Gastrointestinal Sciences

Robert Reznik
Andrew Eugene Hendifar
Richard Tuli

Frontiers in Physiology

doi 10.3389/fphys.2014.00087

9,317 views
23 citations

Review

Published on 03 Mar 2014

Pancreatic cancer cachexia: a review of mechanisms and therapeutics

in Gastrointestinal Sciences

Carlyn Rose Tan
Laith Jamil
Patrick Yaffee
Richard Tuli
Nick Nissen
Simon Lo
Stephen J Pandol
Andrew Eugene Hendifar

Frontiers in Physiology

doi 10.3389/fphys.2014.00088

26,186 views
107 citations

Mini Review

Published on 20 Feb 2014

Pancreatic cancer risk in hereditary pancreatitis

in Gastrointestinal Sciences

Frank Ulrich Weiss

Frontiers in Physiology

doi 10.3389/fphys.2014.00070

16,391 views
57 citations

Review

Published on 14 Feb 2014

Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progression

in Gastrointestinal Sciences

Jeremy Somers Wilson
Romano Cesare Pirola
Minoti Apte

Frontiers in Physiology

doi 10.3389/fphys.2014.00052

17,733 views
82 citations

Original Research

Published on 04 Feb 2014

Inflammation induced by mast cell deficiency rather than the loss of interstitial cells of Cajal causes smooth muscle dysfunction in W/Wv mice

in Gastrointestinal Sciences

John H. Winston
Jinghong Chen
Xuan-Zheng Shi
Sushil K. Sarna

Frontiers in Physiology

doi 10.3389/fphys.2014.00022

6,252 views
9 citations

566 articles

articles

A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes

Human liver myofibroblasts during development and diseases with a focus on portal (myo)fibroblasts

Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure

Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production

What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?

The hop constituent xanthohumol exhibits hepatoprotective effects and inhibits the activation of hepatic stellate cells at different levels

Chemical coding and chemosensory properties of cholinergic brush cells in the mouse gastrointestinal and biliary tract

High fat feeding affects the number of GPR120 cells and enteroendocrine cells in the mouse stomach

Allosteric modulation of Ras and the PI3K/AKT/mTOR pathway: emerging therapeutic opportunities

Risk factors for pancreatic cancer: underlying mechanisms and potential targets

Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models

Diabetes, pancreatic cancer, and metformin therapy

Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC- pathway and modulated by endogenous H2S

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts

Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells

Recent advances in pancreatology

Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin

Receptors for short-chain fatty acids in brush cells at the “gastric groove”

Role of pancreatic stellate cells in chemoresistance in pancreatic cancer

Genetic determinants and potential therapeutic targets for pancreatic adenocarcinoma

Pancreatic cancer cachexia: a review of mechanisms and therapeutics

Pancreatic cancer risk in hereditary pancreatitis

Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progression

Inflammation induced by mast cell deficiency rather than the loss of interstitial cells of Cajal causes smooth muscle dysfunction in W/Wv mice