Frontiers in Physiology | Integrative Physiology

Original Research

Published on 08 Aug 2025

Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca2+-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsynaptic protein expression and function

in Integrative Physiology

Beatrice Cannata
Laura Sposito
Martina Albini
Giuseppe Aceto
Giulia Puliatti
Giacomo Lazzarino
Cristian Ripoli
Maria Rosaria Tropea
Daniela Puzzo
Roberto Piacentini

Frontiers in Physiology

doi 10.3389/fphys.2025.1662171

1,781 views

Original Research

Published on 05 Aug 2025

The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis

in Integrative Physiology

Yan Zhang
Xueju Wang
Xuefeng Wang
Gengdi Huang

Frontiers in Physiology

doi 10.3389/fphys.2025.1633028

1,915 views

Editorial

Published on 28 Jul 2025

Editorial: Unraveling the interconnected dynamics of exercise metabolism, environmental stress, and nutritional factors

in Integrative Physiology

Ignacio Bartolomé Sánchez
Víctor Toro-Román
Jesús Siquier-Coll
Ciro José Brito

Frontiers in Physiology

doi 10.3389/fphys.2025.1665703

1,154 views

Original Research

Published on 16 Jul 2025

Overuse injury induces persistent behavioral declines that correlate with higher IL-6 expression in the affected musculoskeletal tissues, circulation, and brain

in Integrative Physiology

Mary F. Barbe
Alex G. Lambi
Michele Y. Harris
Parth R. Patel
Istvan P. Tamas
Elizabeth R. McGonagle
Megan Van Der Bas
Betsy A. Kalicharan
Lewis Bright-Rowe
Steven N. Popoff

Frontiers in Physiology

doi 10.3389/fphys.2025.1500795

2,242 views

Review

Published on 15 Jul 2025

Hemodynamic homeostasis disequilibrium in critical illness

in Integrative Physiology

Jie Wang
Xiaoting Wang
Dawei Liu
Hui Lian
Guangjian Wang
Zewen Tong
Qingyu Deng
Qirui Guo
Qian Zhang
Yangong Chao

Frontiers in Physiology

doi 10.3389/fphys.2025.1503320

5,162 views

Editorial

Published on 09 Jul 2025

Editorial: Frontiers in the midlands society of physiological sciences (2023-2024)

in Integrative Physiology

Sathish Kumar Natarajan
Hong Zheng
Surabhi Chandra
Harold D. Schultz
William C. W. Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1654264

1,395 views

Review

Published on 26 Jun 2025

Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential

in Integrative Physiology

Cristina Porcari
Stefano Cattaneo
Lucia Crippa
Michele Simonato
Barbara Bettegazzi

Frontiers in Physiology

doi 10.3389/fphys.2025.1618330

3,560 views
3 citations

Original Research

Published on 24 Jun 2025

Interplay between sex, age, BMI, health-related quality of life, and coping strategies in amateur and professional athletes

in Integrative Physiology

Walter Sapuppo
Davide Giacconi
Antonietta Monda
Antonietta Messina
Daniele Saccenti
Claudia Maria Mineo
Maria Casillo
Salvatore Allocca
Giovanni Michelini
Regina Gregori Grgič

Frontiers in Physiology

doi 10.3389/fphys.2025.1626037

2,026 views
1 citation

Review

Published on 19 Jun 2025

Vision toolkit part 1. Neurophysiological foundations and experimental paradigms in eye-tracking research: a review

in Integrative Physiology

Quentin Laborde
Axel Roques
Matthieu P. Robert
Allan Armougum
Nicolas Vayatis
Ioannis Bargiotas
Laurent Oudre
Pierre-Paul Vidal

Frontiers in Physiology

doi 10.3389/fphys.2025.1571534

2,156 views
1 citation

Original Research

Published on 18 Jun 2025

Rat retinal function attenuation with IOP elevation is impacted by both blood pressure and intracranial pressure

in Integrative Physiology

Sera N. Ganearachchi
Anna K. van Koeverden
Christine T. O. Nguyen
Zheng He
Vickie H. Y. Wong
Bang V. Bui
Da Zhao

Frontiers in Physiology

doi 10.3389/fphys.2025.1566032

1,303 views
1 citation

Original Research

Published on 10 Jun 2025

Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation

in Integrative Physiology

Jianwei Peng
Zaoshang Chang
Jinyun Wang
Zijie Liao
Yunjie Yang
Lianwei Mu
Shen Wang
Junhao Huang
Jingbo Xia
Min Hu

Frontiers in Physiology

doi 10.3389/fphys.2025.1608268

2,694 views

Original Research

Published on 09 Jun 2025

Impact of polyethylene terephthalate nanoplastics (PET) on fibroblasts: a study on NIH-3T3 cells

in Integrative Physiology

Maria Elena Giordano
Francesca Lionetto
Maria Giulia Lionetto

Frontiers in Physiology

doi 10.3389/fphys.2025.1580682

2,563 views
2 citations

Original Research

Published on 30 May 2025

Fecal or bacterial transplantation in mice transfer environment-induced brain plasticity and associated behavioral changes

in Integrative Physiology

Francesco Marrocco
Rizwan Khan
Alice Reccagni
Xingzi Lin
Mary Delli Carpini
Valerio Iebba
Giuseppina D’Alessandro
Cristina Limatola

Frontiers in Physiology

doi 10.3389/fphys.2025.1572854

2,123 views

Review

Published on 27 May 2025

Circadian clocks and their role in kidney and eye diseases across organ systems

in Integrative Physiology

Xiuli Chen
Wenxiao Zhang
Yue Gu
Shenzhen Huang

Frontiers in Physiology

doi 10.3389/fphys.2025.1583502

3,825 views
3 citations

Editorial

Published on 15 May 2025

Editorial: Biological rhythms in the brain and gastrointestinal tract

in Integrative Physiology

Jingling Jin
Nange Jin
Byung Joo Kim
Maria Nathalia Moraes
Leonardo V. M. de Assis

Frontiers in Physiology

doi 10.3389/fphys.2025.1622475

1,913 views

Original Research

Published on 15 May 2025

Physical and metabolic requirements of elite military divers

in Integrative Physiology

Karen R. Kelly
Laura J. Palombo
Andrea C. Givens
Jake R. Bernards
Daniel Bennett

Frontiers in Physiology

doi 10.3389/fphys.2025.1505363

1,808 views

Review

Published on 06 May 2025

S-nitrosylation of cardiac myocyte proteins may underlie sex differences in cardiac disease

in Integrative Physiology

Esther U. Asamudo
Raquel E. Parackal
Jeffrey R. Erickson
Donald M. Bers

Frontiers in Physiology

doi 10.3389/fphys.2025.1565917

3,116 views
1 citation

Review

Published on 06 May 2025

Continuous personalized cerebrovascular reactivity-based physiologic metrics in neurocritical care: a narrative review of the current landscape, limitations, and future directions

in Integrative Physiology

Kevin Y. Stein
Logan Froese
Rakibul Hasan
Amanjyot Singh Sainbhi
Nuray Vakitbilir
Tobias Bergmann
Abrar Islam
Noah Silvaggio
Mansoor Hayat
Frederick A. Zeiler

Frontiers in Physiology

doi 10.3389/fphys.2025.1582813

2,428 views
1 citation

Original Research

Published on 28 Apr 2025

Exercise training reduces cardiac fibrosis, promoting improvement in arrhythmias and cardiac dysfunction in an experimental model of chronic chagasic cardiomyopathy

in Integrative Physiology

Alex Cleber Improta-Caria
Carolina Kymie Vasques Nonaka
Pâmela Santana Daltro
Carine Machado Azevedo
Breno Cardim Barreto
Gisele Batista Carvalho
Juliana Fraga Vasconcelos
Bruno Solano de Freitas Souza
Simone Garcia Macambira
Milena Botelho Pereira Soares

Frontiers in Physiology

doi 10.3389/fphys.2025.1558678

2,198 views
1 citation

Review

Published on 28 Apr 2025

Sex differences in the sensitization of prenatally programmed hypertension

in Integrative Physiology

Baojian Xue
Alan Kim Johnson
Alexander G. Bassuk

Frontiers in Physiology

doi 10.3389/fphys.2025.1589615

1,997 views
1 citation

Original Research

Published on 15 Apr 2025

Alteration of vasopressin-aquaporin system in hindlimb unloading mice

in Integrative Physiology

Marianna Ranieri
Maria Venneri
Giuseppina Storlino
Angela Ferrulli
Mariagrazia D’Agostino
Mariangela Centrone
Annarita Di Mise
Roberta Zerlotin
Grazia Tamma
Maria Grano

Frontiers in Physiology

doi 10.3389/fphys.2025.1535053

2,015 views

Mini Review

Published on 08 Apr 2025

A whole system approach to promoting health and human performance in military settings as vital prerequisites for force readiness and operational capability

in Integrative Physiology

Joanne L. Fallowfield
Jace R. Drain
Julia Carins
Helen Kilding
Emma Williams
Ben Fisher
Debra Hayhurst
Alysia Gourlay
Simon Olivotto
Garrett Bullock

Frontiers in Physiology

doi 10.3389/fphys.2025.1541256

3,561 views
1 citation

Review

Published on 27 Mar 2025

Angiotensin-(1-7) protective effects in neurocognitive disorders: molecular mechanisms to therapeutic implications

in Integrative Physiology

Lillia C. Lucas
Katherine D. Kimbark
Victoria L. Vernail
Yuval Silberman
Amy C. Arnold

Frontiers in Physiology

doi 10.3389/fphys.2025.1565270

2,204 views
7 citations

Original Research

Published on 26 Mar 2025

Interleukins expression by rat Lymphocytes exposed to chronic intermittent normobaric hypoxia

in Integrative Physiology

Rodrigo Calderon-Jofre
Giuliano Bernal
Daniel Moraga
Fernando A. Moraga

Frontiers in Physiology

doi 10.3389/fphys.2025.1520174

1,888 views

1,742 articles

articles

Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca2+-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsynaptic protein expression and function

The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis

Editorial: Unraveling the interconnected dynamics of exercise metabolism, environmental stress, and nutritional factors

Overuse injury induces persistent behavioral declines that correlate with higher IL-6 expression in the affected musculoskeletal tissues, circulation, and brain

Hemodynamic homeostasis disequilibrium in critical illness

Editorial: Frontiers in the midlands society of physiological sciences (2023-2024)

Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential

Interplay between sex, age, BMI, health-related quality of life, and coping strategies in amateur and professional athletes

Vision toolkit part 1. Neurophysiological foundations and experimental paradigms in eye-tracking research: a review

Rat retinal function attenuation with IOP elevation is impacted by both blood pressure and intracranial pressure

Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation

Impact of polyethylene terephthalate nanoplastics (PET) on fibroblasts: a study on NIH-3T3 cells

Fecal or bacterial transplantation in mice transfer environment-induced brain plasticity and associated behavioral changes

Circadian clocks and their role in kidney and eye diseases across organ systems

Editorial: Biological rhythms in the brain and gastrointestinal tract

Physical and metabolic requirements of elite military divers

S-nitrosylation of cardiac myocyte proteins may underlie sex differences in cardiac disease

Continuous personalized cerebrovascular reactivity-based physiologic metrics in neurocritical care: a narrative review of the current landscape, limitations, and future directions

Exercise training reduces cardiac fibrosis, promoting improvement in arrhythmias and cardiac dysfunction in an experimental model of chronic chagasic cardiomyopathy

Sex differences in the sensitization of prenatally programmed hypertension

Alteration of vasopressin-aquaporin system in hindlimb unloading mice

A whole system approach to promoting health and human performance in military settings as vital prerequisites for force readiness and operational capability

Angiotensin-(1-7) protective effects in neurocognitive disorders: molecular mechanisms to therapeutic implications

Interleukins expression by rat Lymphocytes exposed to chronic intermittent normobaric hypoxia