Frontiers in Physiology | Metabolic Physiology

Original Research

Published on 11 May 2026

Glycemic efficacy of insulin icodec and risk factors for hypoglycemia in patients with type 2 diabetes mellitus: a real-world study

in Metabolic Physiology

Xiaodong Wanyan
Min Lin
Jianqing Tian
Yanmei Lin

Frontiers in Physiology

doi 10.3389/fphys.2026.1824651

325 views

Original Research

Accepted on 04 May 2026

The 2R,3R isomer of 2,3-butanediol prevents weight gain and decreases plasma glucose concentration of mice fed a fat-enriched diet

in Metabolic Physiology

Sunil Veeravalli
Toryn Poolman
Jeremy Everett
Ian Randall Phillips
Elizabeth A Shephard

Frontiers in Physiology

125 views

Original Research

Accepted on 04 May 2026

Knockout of IGFBP3 improves Alcohol-induced Liver injury via Akt/GSK3β and TMEM219/Caspase 8 Pathways

in Metabolic Physiology

Huimei Cai
Chenyu Zhu
Xi Zheng
Yiqi Lian
Enqi Tang
Yushan Chen
Wenyu Cao
Ying Sun
Yi Lv

Frontiers in Physiology

148 views

Review

Accepted on 04 May 2026

Targeting Necroptosis: How does exercise protect against metabolic dysfunction-associated fatty liver disease?

in Metabolic Physiology

Wenjing Song
Zhifei Ke

Frontiers in Physiology

111 views

Systematic Review

Accepted on 29 Apr 2026

Does acute caffeine ingestion improve high-intensity interval exercise performance? A systematic review and meta-analysis

in Metabolic Physiology

Yixiang Peng
Lei He
Wenxin Du
Baiyu Liu
Xinkai Wang
Kai Xu
Yun Gong

Frontiers in Physiology

296 views

Review

Accepted on 29 Apr 2026

GABA-Mediated Regulation of Lipid Metabolism: A Conserved Relation with Diverse Physiological Significances

in Metabolic Physiology

Samjhana Pradhan
Kavita Sharma
Sanaly Nava
Kristina Hall
Javier Ochoa-Repáraz

Frontiers in Physiology

181 views

Original Research

Published on 29 Apr 2026

Analysis of fatty acids concentration in the liver of rats with diet-induced obesity after bariatric surgery and a high-fat/high-sugar diet

in Metabolic Physiology

Wojciech Kazura
Katarzyna Michalczyk
Bronisława Skrzep-Poloczek
Marek Michalski
Jerzy Jochem
Elżbieta Chełmecka
Ewa Kaczmar
Jakub Poloczek
Michał Kukla
Dominika Stygar

Frontiers in Physiology

doi 10.3389/fphys.2026.1784452

468 views

Original Research

Published on 28 Apr 2026

From gut to brain: short-term ketogenic diet alleviates status epilepticus-induced cognitive deficits in rats

in Metabolic Physiology

Yimin Chen
Wanyin Xu
Qun Hou
Yan Jiang

Frontiers in Physiology

doi 10.3389/fphys.2026.1752371

553 views

Original Research

Published on 22 Apr 2026

Comparative associative and discriminative value of inflammatory, coagulation, hypoxia–perfusion, and electrolyte–metabolic indices for early respiratory physiological decompensation in acute pancreatitis

in Metabolic Physiology

Xiangyin Lv
Jiejun Hu
Jiao Bao

Frontiers in Physiology

doi 10.3389/fphys.2026.1775368

457 views

Correction

Published on 20 Apr 2026

Correction: Resting metabolic rate fluctuations across the menstrual cycle: a systematic review

in Metabolic Physiology

Anežka Hurtová
Marta Gimunová
Michaela Beníčková

Frontiers in Physiology

doi 10.3389/fphys.2026.1854612

329 views

Original Research

Published on 10 Apr 2026

Role of certain adipokines in the pathophysiology of hypertension

in Metabolic Physiology

Ahmet Yilmaz
Basra Deniz Obay
Aysun Ekinci

Frontiers in Physiology

doi 10.3389/fphys.2026.1762472

604 views

Review

Published on 10 Apr 2026

Metabolic inflammation at the adipose-brain axis

in Metabolic Physiology

Saudina Mateus-Gomes
Amnah Al-Sayyar
Baptiste Lobey
Agnes Nadjar
Rejane Rua
Rasheed Ahmad

Frontiers in Physiology

doi 10.3389/fphys.2026.1795058

981 views

Systematic Review

Published on 27 Mar 2026

Resting metabolic rate fluctuations across the menstrual cycle: a systematic review

in Metabolic Physiology

Anežka Hurtová
Marta Gimunová
Michaela Beníčková

Frontiers in Physiology

doi 10.3389/fphys.2026.1778735

1,347 views

Original Research

Published on 25 Mar 2026

Acetate and combinations of short-chain fatty acids increase oxidative phenotype and contribute to muscle fiber type shift in myotubes

in Metabolic Physiology

Britt M.J. Otten
Mireille M. J. P. E. Sthijns
Harry R. Gosker
Marco C. J. M. Kelders
Freddy J. Troost

Frontiers in Physiology

doi 10.3389/fphys.2026.1757576

577 views

Review

Published on 11 Mar 2026

The gut-thyroid axis: physiological regulation of barrier function, microbiota, endocrine signaling and the consequences on energy metabolism

in Metabolic Physiology

Lucia Acampora
Federica Restolfer
Pierluigi De Pierro
Maria Masulli
Monica Dentice
Giovanni Sarnelli
Annunziata Gaetana Cicatiello

Frontiers in Physiology

doi 10.3389/fphys.2026.1753136

1,234 views

Perspective

Published on 19 Feb 2026

Hypoxia-inducible factors in the immunometabolism of metabolic dysfunction-associated steatotic liver disease (MASLD): molecular mechanisms and therapeutic implications

in Metabolic Physiology

Yinan Zhao
Yige Wang
Faying Li
Guoying Yu

Frontiers in Physiology

doi 10.3389/fphys.2026.1779019

621 views

Original Research

Published on 16 Feb 2026

The mechanisms of energy balance between oxidative phosphorylation and glycolysis in human ovarian granulosa cells

in Metabolic Physiology

Jing Wang
Gai-Jing Wang
Ling-Chao Wang
Lu-Lu Wang
Jin-Jin Qin
Bei Wang
Jie Cui
Hong-Li Wu
Rui Li
Wei Liu

Frontiers in Physiology

doi 10.3389/fphys.2026.1715312

504 views

Original Research

Published on 16 Jan 2026

Fasting vs. post-breakfast tabata exercise: implications for substrate metabolism and energy expenditure in young normal-weight women

in Metabolic Physiology

Yongbo Wang
Yanbai Han
Zhuoyue Cheng
Yaqing Fan
Hongli Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1721312

1,604 views

Original Research

Published on 15 Jan 2026

Pyridoxamine reduces inflammatory and microcirculatory abnormalities in metabolic dysfunction-associated steatohepatitis and modulates key factors in the hepatic AGE/ALE signaling pathway

in Metabolic Physiology

Raquel Rangel Silvares
Beatriz Peres de Araujo
Evelyn Nunes Goulart Da Silva Pereira
Karine Lino Rodrigues
Juliana Magalhães Chaves Barbosa
Juliana Florencio da Silva
Vivian Vieira Dias da Silva
Marjo Van de aarenburg
Jean Scheijen
Kristiaan Wouters

Frontiers in Physiology

doi 10.3389/fphys.2025.1736221

1,486 views

Review

Published on 12 Jan 2026

Immunometabolic programming of macrophages in asthma pathogenesis and therapy

in Metabolic Physiology

Lisha Lu
Mengdi Shi
Wen Qin
Mingshu Yang
Xiaochang Wang
Youpeng Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1736340

2,015 views
2 citations

Correction

Published on 09 Jan 2026

Correction: Mechanisms of metabolic transition in hypertrophic cardiomyopathy

in Metabolic Physiology

Conghao Tan
Zhexuan Guo
Junjie Zhou
Wei Yuan

Frontiers in Physiology

doi 10.3389/fphys.2025.1764781

608 views

Brief Research Report

Published on 07 Jan 2026

Heterozygous CYP27B1 c.262delG pathogenic variant and its impact on vitamin D metabolites and phosphocalcic profile in humans

in Metabolic Physiology

Lysanne Girard
Carol-Ann Fortin
Rosalie Plourde
Véronique Desgagné
Renée Guérin
Caroline Albert
Mathieu Desmeules
Patrice Perron
Luigi Bouchard

Frontiers in Physiology

doi 10.3389/fphys.2025.1716877

977 views

Original Research

Published on 07 Jan 2026

The role of impaired adipogenesis in insulin resistance among non-obese individuals

in Metabolic Physiology

Shamma Almuraikhy
Maha Alser
Khaled Naja
Najeha Anwardeen
Samir Taha
Jomon John
Sharique Halim
Saif Badran
Mohamed Badie Ahmed
Salma Jarrar

Frontiers in Physiology

doi 10.3389/fphys.2025.1739215

1,246 views

Systematic Review

Published on 08 Dec 2025

Orexinergic pathway as a potential therapeutic candidate for the modulation of glucose homeostasis

in Metabolic Physiology

Jean Claude Hakizimana
Pelagie Izabayo
Zephyrin Izukwizabigenza
Abdullateef Isiaka Alagbonsi

Frontiers in Physiology

doi 10.3389/fphys.2025.1659753

2,637 views
6 citations

244 articles

articles

Glycemic efficacy of insulin icodec and risk factors for hypoglycemia in patients with type 2 diabetes mellitus: a real-world study

The 2R,3R isomer of 2,3-butanediol prevents weight gain and decreases plasma glucose concentration of mice fed a fat-enriched diet

Knockout of IGFBP3 improves Alcohol-induced Liver injury via Akt/GSK3β and TMEM219/Caspase 8 Pathways

Targeting Necroptosis: How does exercise protect against metabolic dysfunction-associated fatty liver disease?

Does acute caffeine ingestion improve high-intensity interval exercise performance? A systematic review and meta-analysis

GABA-Mediated Regulation of Lipid Metabolism: A Conserved Relation with Diverse Physiological Significances

Analysis of fatty acids concentration in the liver of rats with diet-induced obesity after bariatric surgery and a high-fat/high-sugar diet

From gut to brain: short-term ketogenic diet alleviates status epilepticus-induced cognitive deficits in rats

Comparative associative and discriminative value of inflammatory, coagulation, hypoxia–perfusion, and electrolyte–metabolic indices for early respiratory physiological decompensation in acute pancreatitis

Correction: Resting metabolic rate fluctuations across the menstrual cycle: a systematic review

Role of certain adipokines in the pathophysiology of hypertension

Metabolic inflammation at the adipose-brain axis

Resting metabolic rate fluctuations across the menstrual cycle: a systematic review

Acetate and combinations of short-chain fatty acids increase oxidative phenotype and contribute to muscle fiber type shift in myotubes

The gut-thyroid axis: physiological regulation of barrier function, microbiota, endocrine signaling and the consequences on energy metabolism

Hypoxia-inducible factors in the immunometabolism of metabolic dysfunction-associated steatotic liver disease (MASLD): molecular mechanisms and therapeutic implications

The mechanisms of energy balance between oxidative phosphorylation and glycolysis in human ovarian granulosa cells

Fasting vs. post-breakfast tabata exercise: implications for substrate metabolism and energy expenditure in young normal-weight women

Pyridoxamine reduces inflammatory and microcirculatory abnormalities in metabolic dysfunction-associated steatohepatitis and modulates key factors in the hepatic AGE/ALE signaling pathway

Immunometabolic programming of macrophages in asthma pathogenesis and therapy

Correction: Mechanisms of metabolic transition in hypertrophic cardiomyopathy

Heterozygous CYP27B1 c.262delG pathogenic variant and its impact on vitamin D metabolites and phosphocalcic profile in humans

The role of impaired adipogenesis in insulin resistance among non-obese individuals

Orexinergic pathway as a potential therapeutic candidate for the modulation of glucose homeostasis