Frontiers in Physiology | Respiratory Physiology and Pathophysiology

Original Research

Published on 01 Oct 2025

The impact of obesity on upper airway anatomy as assessed by magnetic resonance imaging and obstructive sleep apnea endotypic traits

in Respiratory Physiology and Pathophysiology

Brandon Nokes
Aaron Schueler
Chantal Darquenne
Cristopher N. Schmickl
Brian S. Wojeck
Stacie Moore
Pamela Deyoung
Lana McGinnis
Rebecca J. Theilmann
Eli Gruenberg

Frontiers in Physiology

doi 10.3389/fphys.2025.1648767

2,558 views

Original Research

Published on 26 Sep 2025

Between endothelial activation and stress index (EASIX) and mortality in acute respiratory distress syndrome (ARDS) patients: a multicenter retrospective study

in Respiratory Physiology and Pathophysiology

Juan Chen
Jing Lv
Meijun Liu
Xue Dai
Wang Deng

Frontiers in Physiology

doi 10.3389/fphys.2025.1570988

2,468 views
1 citation

Original Research

Published on 24 Sep 2025

Effects of oral, oronasal, and oronasal breathing with a decongested nose during incremental maximal exercise testing of well-trained endurance athletes: a randomized cross-over study

in Respiratory Physiology and Pathophysiology

J. Bergqvist
F. Reite
F. Edin
L. Schiöler
M. Börjesson
S. Steinsvåg
S. Pettersson
J. Hellgren

Frontiers in Physiology

doi 10.3389/fphys.2025.1654725

3,118 views

Methods

Published on 24 Sep 2025

Perspectives on physics-based one-dimensional modeling of lung physiology

in Respiratory Physiology and Pathophysiology

Aranyak Chakravarty
Debjit Kundu
Mahesh V. Panchagnula
Alladi Mohan
Neelesh A. Patankar

Frontiers in Physiology

doi 10.3389/fphys.2025.1635983

2,192 views
2 citations

Original Research

Published on 19 Sep 2025

Computational modeling of cough-induced droplets and mucosal film dynamics in the upper airway for pulmonary disease classification

in Respiratory Physiology and Pathophysiology

Olusegun J. Ilegbusi
Rafid Jahangir Khan
Bari Hoffman

Frontiers in Physiology

doi 10.3389/fphys.2025.1666826

2,369 views
1 citation

Original Research

Published on 19 Sep 2025

Under the background of the new global definition of ARDS: an interpretable machine learning approach for predicting 28-day ICU mortality in patients with sepsis complicated by ARDS

in Respiratory Physiology and Pathophysiology

Peijie Zhang
Shuo Yuan
Shuzhan Zhang
Zhiheng Yuan
Zi Ye
Lanxin Lv
Hongning Yang
Hui Peng
Haiquan Li
Ningjun Zhao

Frontiers in Physiology

doi 10.3389/fphys.2025.1617196

3,495 views
2 citations

Original Research

Published on 16 Sep 2025

Small scale electrostatically-driven aerosol deposition in airway-on-chip models of bronchial constriction

in Respiratory Physiology and Pathophysiology

Ron Bessler
Tirosh Mekler
Rami Fishler
Oshri Farhana
Sigal Dhatavkar
Tamar Daniel
Bar Kalifa
Kenichiro Koshiyama
Netanel Korin
Josué Sznitman

Frontiers in Physiology

doi 10.3389/fphys.2025.1621177

2,390 views

Review

Published on 15 Sep 2025

Mitochondria as the central regulator of cell death in bronchopulmonary dysplasia

in Respiratory Physiology and Pathophysiology

Fan Zhang
Laishuan Wang
Yahui Zhou

Frontiers in Physiology

doi 10.3389/fphys.2025.1685526

2,993 views

Original Research

Published on 12 Sep 2025

Lung uptake of two SPECT markers identifies sensitivity to hyperoxia-induced acute respiratory distress syndrome in rats

in Respiratory Physiology and Pathophysiology

Anne V. Clough
Pardis Taheri
Guru P. Sharma
Ming Zhao
Elizabeth R. Jacobs
Said H. Audi

Frontiers in Physiology

doi 10.3389/fphys.2025.1648159

1,822 views

Review

Published on 09 Sep 2025

Advances in home-based respiratory muscle training for improving physical function in older adults with long COVID

in Respiratory Physiology and Pathophysiology

Xu Guo
Xuemei Li

Frontiers in Physiology

doi 10.3389/fphys.2025.1662537

3,233 views

Original Research

Published on 05 Sep 2025

Altered actin isoforms expression and enhanced airway responsiveness in asthma: the crucial role of β-cytoplasmic actin

in Respiratory Physiology and Pathophysiology

Marisol Alvarez-González
Angélica Flores-Flores
Verónica Carbajal-Salinas
Blanca Bazán-Perkins

Frontiers in Physiology

doi 10.3389/fphys.2025.1627443

2,217 views
1 citation

Systematic Review

Published on 13 Aug 2025

Vagus nerve stimulation as a potential treatment for acute asthmatic bronchoconstriction: a systematic review

in Respiratory Physiology and Pathophysiology

Elizabeth Di Flumeri
Francine M. Ducharme
Joël St-Pierre
Farbod Niazi
Nathan A. Shlobin
Simon Couillard
Jean-Paul Praud
Alexander G. Weil
Christian Iorio-Morin

Frontiers in Physiology

doi 10.3389/fphys.2025.1625871

5,456 views
1 citation

Original Research

Published on 29 Jul 2025

Patient-specific estimation of distal lung morphometry using aerosol deposition data

in Respiratory Physiology and Pathophysiology

S. G. Karthiga Devi
Alladi Mohan
Kalawat T.C
Mahesh V. Panchagnula

Frontiers in Physiology

doi 10.3389/fphys.2025.1611545

1,484 views

Systematic Review

Published on 25 Jul 2025

An updated insight into the effect of β-adrenergic receptor antagonists (β-blockers) on respiratory function in asthma patients: a systematic review and meta-analysis

in Respiratory Physiology and Pathophysiology

Monika Marko
Rafał Pawliczak

Frontiers in Physiology

doi 10.3389/fphys.2025.1582740

4,124 views
2 citations

Original Research

Published on 16 Jul 2025

Clinical study on modified Shenzhe Zhenqi Decoction combined with ambroxol hydrochloride in the treatment of severe pneumonia

in Respiratory Physiology and Pathophysiology

Binyu Xing
Cunyi Shen
Ting Lin
Xiaoning Li
Wenjun Tan

Frontiers in Physiology

doi 10.3389/fphys.2025.1601761

1,902 views

Original Research

Published on 01 Jul 2025

Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HIF-1α signaling pathway

in Respiratory Physiology and Pathophysiology

Yuchan Zhou
Yuting Wang
Delong Yu
Xiaoyan Liu
Wenjuan Cao
Huanhuan Li
Ye Gu
Liqun Hu
Yupeng Bai

Frontiers in Physiology

doi 10.3389/fphys.2025.1573405

1,984 views

Original Research

Published on 30 Jun 2025

Fe2O3 nanoparticles disrupt microstructure and reduce the viscoelasticity of simulated asthma airway mucus for potential airway mucus clearance applications

in Respiratory Physiology and Pathophysiology

Jiayuan Zhong
Lei Shi
Zhiwei Liu
Kai Ni
Lei Liu
Yan Pan
Jingjing Li
Xiaowei Yu
Linhong Deng
Mingzhi Luo

Frontiers in Physiology

doi 10.3389/fphys.2025.1566716

1,797 views

Original Research

Published on 26 Jun 2025

An optimization method for hemi-diaphragm measurement of dynamic chest X-ray radiography during respiration based on graphics and diaphragm motion consistency criterion

in Respiratory Physiology and Pathophysiology

Yingjian Yang
Jie Zheng
Peng Guo
Tianqi Wu
Qi Gao
Yong Li
Chengcheng Liu
Yang Liu
Yingwei Guo
Huai Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1528067

2,247 views
1 citation

Original Research

Published on 23 Jun 2025

Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner

in Respiratory Physiology and Pathophysiology

Amy Fagan
Mariana Sponchiado
Luz Mata
Shanil Amin
J. Ignacio Aguirre
Sreekala Prabhakaran
Leah R. Reznikov

Frontiers in Physiology

doi 10.3389/fphys.2025.1578553

1,972 views
1 citation

Original Research

Published on 13 Jun 2025

A feedback-driven ventilation model for assessing airway secretions in mechanically ventilated patients

in Respiratory Physiology and Pathophysiology

D. Vijay Anand
Manuel Teixeira Cabeleira
Claire Black
Vanessa Diaz-Zuccarini
Nicholas C. Ovenden

Frontiers in Physiology

doi 10.3389/fphys.2025.1612501

2,520 views

Case Report

Published on 02 Jun 2025

Weaning management in a patient with heart dysfunction: a case report

in Respiratory Physiology and Pathophysiology

Haobo Jiang
Meiling Lao
Weixian Xu
Yunhai Zhang

Frontiers in Physiology

doi 10.3389/fphys.2025.1609975

1,808 views

Original Research

Published on 30 May 2025

Longitudinal analysis of coal workers’ pneumoconiosis using enhanced resolution-computed tomography images: unveiling patterns in lung structure, function, and clinical correlations

in Respiratory Physiology and Pathophysiology

Ngan-Khanh Chau
Eun-Kee Park
Sanghun Choi

Frontiers in Physiology

doi 10.3389/fphys.2025.1578058

2,443 views
3 citations

Original Research

Published on 15 May 2025

Investigating pulmonary inflammation and injury after progressive systemic inflammation in preterm fetal sheep

in Respiratory Physiology and Pathophysiology

E. G. Vandenberg
S. B. Kelly
V. A. Zahra
H. Lu
A. Thiel
S. B. Hooper
R. Galinsky
G. R. Polglase

Frontiers in Physiology

doi 10.3389/fphys.2025.1542613

2,094 views

Systematic Review

Published on 15 May 2025

The effects of exercise based on adherence to ACSM recommendations on pulmonary function and quality of life in adults with asthma: a systematic review and meta-analysis

in Respiratory Physiology and Pathophysiology

Jinhan Li
Jianxu Zhao
Jiahao Wei
Baofa Wu
Wuzhuang Sun

Frontiers in Physiology

doi 10.3389/fphys.2025.1548382

4,152 views