Frontiers in Psychiatry | Molecular Psychiatry

Original Research

Published on 20 May 2025

Exosomal microRNA signatures in youth at clinical high risk for bipolar disorder

in Molecular Psychiatry

Xinyu Meng
Shengmin Zhang
Yingzhen Xu
Zaohui Ma
Shuzhe Zhou
Yantao Ma
Hong Ma
Xin Yu
Lili Guan

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1589374

1,819 views
1 citation

Original Research

Published on 14 May 2025

Association between GRIN2B DNA methylation and cognitive impairment: a cross-sectional study of patients with bipolar depression

in Molecular Psychiatry

Hao Yu
Chengji Wang
Yao Wu
Changxing He
Shaohong Zou

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1574391

1,856 views

Original Research

Published on 12 May 2025

Unveiling chiral amino acid alterations and glycine dysregulation in late-life depression through targeted metabolomics

in Molecular Psychiatry

Mingxia Liu
Weigang Pan
Jing He
Sihai Ling
Yi He
Jian Yang
Peixian Mao
Zuoli Sun

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1558796

2,441 views

Systematic Review

Published on 29 Apr 2025

Translational interdisciplinary research on human chorionic gonadotropin’s enhancement of neuroendocrine crosstalk: a novel medical hypothesis for systemic adjunctive treatment of psychiatric disorders

in Molecular Psychiatry

João Francisco Pollo Gaspary
Luis Felipe Dias Lopes
Antonio Geraldo Camara

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1537442

2,267 views
1 citation

Original Research

Published on 22 Apr 2025

Genetic association between gene expression profiles in oligodendrocyte precursor cells and psychiatric disorders

in Molecular Psychiatry

Reon Kondo
Hiroki Kimura
Masashi Ikeda

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1566155

3,839 views
3 citations

Editorial

Published on 10 Apr 2025

Editorial: The individual and joint contributions of molecular and environmental factors on gene expression and psychopathology development

in Molecular Psychiatry

Gabriela Ariadna Martínez-Levy
Diego Luiz Rovaris
Rodrigo G. Arzate-Mejía
Jill A. Rabinowitz

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1599378

1,283 views

Original Research

Published on 21 Mar 2025

Sentence-level multi-modal feature learning for depression recognition

in Molecular Psychiatry

Guanghua Zhang
Guangping Zhuo
Yang Yang
Guohua Xu
Shukui Ma
Hao Liu
Zhiyong Ren

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1439577

2,665 views
1 citation

Review

Published on 18 Mar 2025

Knowledge graph and its application in the study of neurological and mental disorders

in Molecular Psychiatry

Qizheng Wang
Fan Yang
Lijie Quan
Mengjie Fu
Zhongli Yang
Ju Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1452557

4,935 views
1 citation

Original Research

Published on 12 Mar 2025

Interplay between polygenic risk and family processes in predicting trajectories of adolescent externalizing behaviors

in Molecular Psychiatry

Jinni Su
Belal Jamil
Kit K. Elam
Angel D. Trevino
Kathryn Lemery-Chalfant
Eleanor K. Seaton
Rick A. Cruz
Kevin J. Grimm

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1505035

2,356 views
1 citation

Original Research

Published on 27 Feb 2025

LncRNA of peripheral blood mononuclear cells: HYMAI acts as a potential diagnostic and therapeutic biomarker for female major depressive disorder

in Molecular Psychiatry

Tianyi Bu
Jiarun Yang
Jiawei Zhou
Yeran Liu
Kexin Qiao
Yan Wang
Jili Zhang
Erying Zhao
Boakye Kwame Owura
Xiaohui Qiu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1241089

1,637 views

Original Research

Published on 20 Feb 2025

Proteome analysis of the prefrontal cortex and the application of machine learning models for the identification of potential biomarkers related to suicide

in Molecular Psychiatry

Manuel Alejandro Rojo-Romero
Nora Andrea Gutiérrez-Nájera
Carlos Sabás Cruz-Fuentes
Ana Luisa Romero-Pimentel
Roberto Mendoza-Morales
Fernando García-Dolores
Mirna Edith Morales-Marín
Xóchitl Castro-Martínez
Elier González-Sáenz
Jonatan Torres-Campuzano

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1429953

4,109 views
1 citation

Original Research

Published on 18 Feb 2025

Utilizing metagenomic profiling and machine learning model to identify bacterial biomarkers for major depressive disorder

in Molecular Psychiatry

Xuan Wang
Di Cao
Hanlin Zhang
Wei Chen
Jiaxin Sun
Huimin Hu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1539596

3,078 views
6 citations

Original Research

Published on 14 Feb 2025

Assessing the feasibility of using salivary microRNAs as biomarkers to distinguish between chronic stress and childhood trauma in African American young women in an exploratory pilot study

in Molecular Psychiatry

Erica Holliday
Anisah Bagasra
Omar Bagasra
Pratima Pandey

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1507064

2,252 views
1 citation

Original Research

Published on 13 Feb 2025

Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study

in Molecular Psychiatry

Vanessa Kiyomi Ota
Adrielle Martins Oliveira
Amanda Victória Gomes Bugiga
Helena B. Conceição
Pedro Alexandre Favoretto Galante
Paula Fontes Asprino
Julia Luiza Schäfer
Mauricio Scopel Hoffmann
Rodrigo Bressan
Elisa Brietzke

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1505421

4,473 views
2 citations

Original Research

Published on 30 Jan 2025

NEK4: prediction of available drug targets and common genetic linkages in bipolar disorder and major depressive disorder

in Molecular Psychiatry

Bin Gong
Chenxu Xiao
Yu Feng
Jing Shen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1414015

3,546 views

Original Research

Published on 29 Jan 2025

Trace amine-associated receptors (TAARs)2-9 knockout mice exhibit reduced wakefulness and disrupted REM sleep

in Molecular Psychiatry

Sunmee Park
Jasmine Heu
Gavin Scheldrup
Ryan K. Tisdale
Yu Sun
Meghan Haire
Shun-Chieh Ma
Marius C. Hoener
Thomas S. Kilduff

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1467964

2,631 views
1 citation

Review

Published on 27 Jan 2025

Pituitary adenylyl cyclase-activating polypeptide modulates the stress response: the involvement of different brain areas and microglia

in Molecular Psychiatry

Anika Singh
Paul Shim
Sadaf Naeem
Shafiqur Rahman
Kabirullah Lutfy

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1495598

2,953 views
3 citations

Opinion

Published on 07 Jan 2025

Body and mind: how obesity triggers neuropsychiatric and neurodegenerative disorders

in Molecular Psychiatry

Claudio Pirozzi
Nicola Opallo
Filomena Del Piano
Stefania Melini
Adriano Lama

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1524555

3,669 views
7 citations

Original Research

Published on 20 Dec 2024

Polygenic risk for epigenetic aging and adverse life experiences interact to predict growth in adolescent depression in a racially/ethnically diverse sample

in Molecular Psychiatry

Kit K. Elam
Jinni Su
Weisiyu Abraham Qin
Kathryn Lemery-Chalfant

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1499395

2,208 views

Original Research

Published on 19 Dec 2024

Trace amine-associated receptor 1 agonist reduces aggression in brain serotonin-deficient tryptophan hydroxylase 2 knockout rats

in Molecular Psychiatry

Ilya S. Zhukov
Yazen Alnefeesi
Natalya A. Krotova
Vsevolod V. Nemets
Konstantin A. Demin
Marina N. Karpenko
Evgeny A. Budygin
Evgeny V. Kanov
Allan V. Kalueff
Petr D. Shabanov

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1484925

2,744 views
6 citations

Systematic Review

Published on 18 Dec 2024

Evaluating virtual reality technology in psychotherapy: impacts on anxiety, depression, and ADHD

in Molecular Psychiatry

Peng Wang
Xiaowen Ai
Xiyang Zhang
Fei Ma
Yan Zhuang
Suogang Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1480788

15,823 views
12 citations

Editorial

Published on 18 Dec 2024

Editorial: Methods and applications in molecular psychiatry: 2023

in Molecular Psychiatry

Sehyoun Yoon
Aye-Mu Myint
Karl Bechter

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1536404

1,156 views

Original Research

Published on 09 Dec 2024

Association between psychiatric symptoms with multiple peripheral blood sample test: a 10-year retrospective study

in Molecular Psychiatry

Jianqing Qiu
Cheng Yu
Yalan Kuang
Yao Hu
Ting Zhu
Ke Qin
Wei Zhang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1481006

2,836 views
1 citation

Mini Review

Published on 25 Nov 2024

Impact of the gut microbiota-Th17 cell axis on inflammatory depression

in Molecular Psychiatry

Xiuzhi Jia
Jiayi Wang
Dan Ren
Kaibo Zhang
Hongliang Zhang
Tengchuan Jin
Songquan Wu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1509191

3,177 views
3 citations

524 articles

articles

Exosomal microRNA signatures in youth at clinical high risk for bipolar disorder

Association between GRIN2B DNA methylation and cognitive impairment: a cross-sectional study of patients with bipolar depression

Unveiling chiral amino acid alterations and glycine dysregulation in late-life depression through targeted metabolomics

Translational interdisciplinary research on human chorionic gonadotropin’s enhancement of neuroendocrine crosstalk: a novel medical hypothesis for systemic adjunctive treatment of psychiatric disorders

Genetic association between gene expression profiles in oligodendrocyte precursor cells and psychiatric disorders

Editorial: The individual and joint contributions of molecular and environmental factors on gene expression and psychopathology development

Sentence-level multi-modal feature learning for depression recognition

Knowledge graph and its application in the study of neurological and mental disorders

Interplay between polygenic risk and family processes in predicting trajectories of adolescent externalizing behaviors

LncRNA of peripheral blood mononuclear cells: HYMAI acts as a potential diagnostic and therapeutic biomarker for female major depressive disorder

Proteome analysis of the prefrontal cortex and the application of machine learning models for the identification of potential biomarkers related to suicide

Utilizing metagenomic profiling and machine learning model to identify bacterial biomarkers for major depressive disorder

Assessing the feasibility of using salivary microRNAs as biomarkers to distinguish between chronic stress and childhood trauma in African American young women in an exploratory pilot study

Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study

NEK4: prediction of available drug targets and common genetic linkages in bipolar disorder and major depressive disorder

Trace amine-associated receptors (TAARs)2-9 knockout mice exhibit reduced wakefulness and disrupted REM sleep

Pituitary adenylyl cyclase-activating polypeptide modulates the stress response: the involvement of different brain areas and microglia

Body and mind: how obesity triggers neuropsychiatric and neurodegenerative disorders

Polygenic risk for epigenetic aging and adverse life experiences interact to predict growth in adolescent depression in a racially/ethnically diverse sample

Trace amine-associated receptor 1 agonist reduces aggression in brain serotonin-deficient tryptophan hydroxylase 2 knockout rats

Evaluating virtual reality technology in psychotherapy: impacts on anxiety, depression, and ADHD

Editorial: Methods and applications in molecular psychiatry: 2023

Association between psychiatric symptoms with multiple peripheral blood sample test: a 10-year retrospective study

Impact of the gut microbiota-Th17 cell axis on inflammatory depression