Frontiers in Psychiatry | Mood Disorders

Original Research

Published on 02 Jan 2026

Proton pump inhibitor use and risk of depression among Sudanese adults: a cross-sectional community-based study

in Mood Disorders

Afnan A. Alwabili
Saeed M. Omar
Eman A. Alotaibi
Ishag Adam

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1689599

121 views

Opinion

Accepted on 31 Dec 2025

Treatment-Resistant Depression: Time to Rethink Current Definitions and Clinical Practice

in Mood Disorders

Walter Paganin

Frontiers in Psychiatry

208 views

Brief Research Report

Accepted on 29 Dec 2025

The Bipolar Disorder Medication Adherence Battery (BD-MAB): Validity, Reliability, and Clinical Benchmarks

in Mood Disorders

Buket Ünver
Özlem Sertel Berk
Nesrin Karamustafalıoğlu

Frontiers in Psychiatry

Original Research

Accepted on 29 Dec 2025

Cross‑national comparison of major depressive disorder burden in China, India, and the United States of America: An age‑period‑cohort analysis of GBD 2021

in Mood Disorders

Chengcheng Zhang
Chun Zhang
Wenjuan Ying
Wei Ma

Frontiers in Psychiatry

Systematic Review

Published on 29 Dec 2025

The effects of berberine on depressive symptoms: a systematic review and meta-analysis of preclinical studies

in Mood Disorders

Xiaona Li
Mei Lu
Xinkun Wang
Di Wu
Yongmei Chen
Ming Tao
Dengqun Gou
Runyu Yang
Jiamei Zhou

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1653929

1,472 views

Original Research

Accepted on 22 Dec 2025

Personalizing Esketamine Treatment in TRD and TRBD: The Role of Mentalization, Rigidity, Psychache, and Suicidality

in Mood Disorders

Miriam Olivola
Filippo Mazzoni
Barbara Tarantino
Alessandro Guffanti
Matteo Marcatili
Monica Macellaro
Nicolaja Girone
Vassilis Martiadis
Fabiola Raffone
Tiziano Prodi

Frontiers in Psychiatry

341 views

Original Research

Accepted on 22 Dec 2025

Efficacy and Safety of Toludesvenlafaxine hydrochloride sustained-release tablets in Depression with Ineffective or Partially Effective Initial Antidepressant Treatment:A Single-Arm,Multicenter Clinical Study

in Mood Disorders

Jingming Yang
Yanyan Jia
Ke Chen
Weiye Liang
Jing Long
Meijuan Li
Qianqian Wei
Jian Wang
Baoping Yan
Keqing Li

Frontiers in Psychiatry

163 views

Correction

Accepted on 19 Dec 2025

Correction: Impact of difficult-to-treat depression for patients and society: a real-world study

in Mood Disorders

Sergio Benavente
Alba Parra
Jorge Lopez-Castroman
Ismael Conejero
Pablo Alonso-Torres
Tatiana Caraballo López
Pablo Carrasco Arteaga
Enrique Baca-García

Frontiers in Psychiatry

Original Research

Accepted on 18 Dec 2025

Affective Forecasting dynamics as an Early Intervention Target in Depression: Evidence from Ecological Monitoring and Temporal Network Analysis

in Mood Disorders

Zhuoya Yang
Xuanang Liu
Yating Wang
Fenghua Li
Yixiao Fu
Zhengzhi Feng
Lei Xia
Chunmeng Shi

Frontiers in Psychiatry

Systematic Review

Published on 17 Dec 2025

Clinical prediction models for post-stroke depression: a systematic review and meta-analysis

in Mood Disorders

Honggang Wu
Yating Xiao
Xin Hu
Chao You
Niandong Zheng
Lu Ma

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1629023

569 views

Perspective

Published on 17 Dec 2025

Regulation as modulation: autonomic flexibility as a physiological buffer in bipolar II disorder — a perspective on somatic regulation and mood stability

in Mood Disorders

Kyndra Purcell

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1726708

628 views

Original Research

Published on 16 Dec 2025

Factors influencing patient decision-making on a multimodal precision medicine algorithm for depression: a qualitative European multicentre study of the PROMPT consortium

in Mood Disorders

Rosa Glaser
Johannes C. S. Zang
Britta Kelch
Silke Jörgens
Inga Stonner
Viktor T. H. Wahner
Ewa Ferensztajn-Rochowiak
Dobrochna Kopeć
Martina Contu
Pasquale Paribello

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1713160

569 views

Original Research

Accepted on 15 Dec 2025

Factors associated with violence in bipolar disorder versus major depressive disorder: insights from a retrospective cross-sectional study of 141 aged patients with mood disorders

in Mood Disorders

Junrong Ye
Tingwei Zhou
Lingli Lei
Lili Mo
Jiao Chen
Wen Wang
Yanheng WEI
Xueling LU
Lexin YUAN
Shengwei WU

Frontiers in Psychiatry

175 views

Review

Accepted on 15 Dec 2025

Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials

in Mood Disorders

Jiamin Fu
Yuchi Zhang
Jing Gao
Ming Lan
Zhixin Zhang
Ruiting Liang
Hongyun Zhou
Shirui Liu
Ziyi Zhou
Jinwan Zhao

Frontiers in Psychiatry

236 views

Original Research

Accepted on 12 Dec 2025

Three-Dimensional Facial Features of Suicide Risk in Females with Depression

in Mood Disorders

Jie Yang
Lingui Chen
Ling Zhang
Jing-Dong Han
Gang Wang

Frontiers in Psychiatry

257 views

Original Research

Accepted on 12 Dec 2025

Thyroid dysfunction in elderly first-episode drug-naïve major depressive disorder patients with comorbid dyslipidemia: prevalence, clinical profile and associated factors

in Mood Disorders

Xiuhua Song
Lei Yi
Shenghai Wang
Xiangyang Zhang

Frontiers in Psychiatry

167 views

Original Research

Accepted on 11 Dec 2025

Toward Precision Psychological Rehabilitation: Predicting CBT Efficacy in Post-Stroke Depression Using Machine Learning

in Mood Disorders

Jingyuan Lin
Jiansong Yu

Frontiers in Psychiatry

128 views

Systematic Review

Accepted on 11 Dec 2025

Effectiveness of unguided digital cognitive behavioral therapy for insomnia(dCBT-i) on depressive symptoms:a systematic review and meta-analysis of randomized controlled trials

in Mood Disorders

Peixuan Zhong
Qian Zhu
Tiemei Li
Li Tong
Wang Haijing
Wen Peng

Frontiers in Psychiatry

177 views

Systematic Review

Accepted on 10 Dec 2025

Clinical efficacy study on the combined treatment of cancer-related depression with traditional Chinese acupuncture-related therapies and drugs

in Mood Disorders

Ying Zhou
Feiqing Wang
Bo Yang
Xu Yang
Xiaoxu Chen
Bingbing Li
Yanqing Liu
Zhenhua Liu
Yang Liu
Dongxin Tang

Frontiers in Psychiatry

163 views

Original Research

Accepted on 10 Dec 2025

Aberrant Functional Connectivity of the Dorsolateral Prefrontal Cortex-Nucleus Accumbens During Naturalistic Stimulation in Adolescent Major Depressive Disorder

in Mood Disorders

Yingzhe Zhao
Xi Zhuo
Zhenxiang Zang
Zhi Yang
Jing Liu

Frontiers in Psychiatry

152 views

Systematic Review

Published on 10 Dec 2025

Exploring the bidirectional relationship between depressive disorder and dyslipidemia: a systematic review and meta-analysis

in Mood Disorders

Xiaxia Jin
Chaobin Kang
Yanrong Lu
Yifan Yang
Feng Zhou
Tao Gao
Xiaochun Liu
Yongmei Yan

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1498773

736 views

Original Research

Published on 10 Dec 2025

The effect of childhood maltreatment on non-suicidal self-injury in adolescents with bipolar disorder: the mediating role of dysfunctional attitudes and the moderating role of social support

in Mood Disorders

Huawei Tan
Dan Zhao
Jiarui Cao
Ting Huang
Jiahui Yi
Zhihui Wan
Fan Zhang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1698424

600 views

Systematic Review

Accepted on 09 Dec 2025

Efficacy of Probiotic Intervention in Unmedicated Depression: A Systematic Review and Meta-Analysis

in Mood Disorders

liu haiyan
wan xiaochao
xiuxiu chen
dan wang
ye liu
zhiguo chen
ting liu

Frontiers in Psychiatry

171 views

Original Research

Published on 09 Dec 2025

Impact of difficult-to-treat depression for patients and society: a real-world study

in Mood Disorders

Sergio Benavente
Alba Parra
Jorge Lopez-Castroman
Ismael Conejero
Pablo Alonso-Torres
Tatiana Caraballo López
Pablo Carrasco Arteaga
Enrique Baca-García

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1702137

666 views

1,671 articles

articles

Proton pump inhibitor use and risk of depression among Sudanese adults: a cross-sectional community-based study

Treatment-Resistant Depression: Time to Rethink Current Definitions and Clinical Practice

The Bipolar Disorder Medication Adherence Battery (BD-MAB): Validity, Reliability, and Clinical Benchmarks

Cross‑national comparison of major depressive disorder burden in China, India, and the United States of America: An age‑period‑cohort analysis of GBD 2021

The effects of berberine on depressive symptoms: a systematic review and meta-analysis of preclinical studies

Personalizing Esketamine Treatment in TRD and TRBD: The Role of Mentalization, Rigidity, Psychache, and Suicidality

Efficacy and Safety of Toludesvenlafaxine hydrochloride sustained-release tablets in Depression with Ineffective or Partially Effective Initial Antidepressant Treatment:A Single-Arm,Multicenter Clinical Study

Correction: Impact of difficult-to-treat depression for patients and society: a real-world study

Affective Forecasting dynamics as an Early Intervention Target in Depression: Evidence from Ecological Monitoring and Temporal Network Analysis

Clinical prediction models for post-stroke depression: a systematic review and meta-analysis

Regulation as modulation: autonomic flexibility as a physiological buffer in bipolar II disorder — a perspective on somatic regulation and mood stability

Factors influencing patient decision-making on a multimodal precision medicine algorithm for depression: a qualitative European multicentre study of the PROMPT consortium

Factors associated with violence in bipolar disorder versus major depressive disorder: insights from a retrospective cross-sectional study of 141 aged patients with mood disorders

Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials

Three-Dimensional Facial Features of Suicide Risk in Females with Depression

Thyroid dysfunction in elderly first-episode drug-naïve major depressive disorder patients with comorbid dyslipidemia: prevalence, clinical profile and associated factors

Toward Precision Psychological Rehabilitation: Predicting CBT Efficacy in Post-Stroke Depression Using Machine Learning

Effectiveness of unguided digital cognitive behavioral therapy for insomnia(dCBT-i) on depressive symptoms:a systematic review and meta-analysis of randomized controlled trials

Clinical efficacy study on the combined treatment of cancer-related depression with traditional Chinese acupuncture-related therapies and drugs

Aberrant Functional Connectivity of the Dorsolateral Prefrontal Cortex-Nucleus Accumbens During Naturalistic Stimulation in Adolescent Major Depressive Disorder

Exploring the bidirectional relationship between depressive disorder and dyslipidemia: a systematic review and meta-analysis

The effect of childhood maltreatment on non-suicidal self-injury in adolescents with bipolar disorder: the mediating role of dysfunctional attitudes and the moderating role of social support

Efficacy of Probiotic Intervention in Unmedicated Depression: A Systematic Review and Meta-Analysis

Impact of difficult-to-treat depression for patients and society: a real-world study