Frontiers in Psychiatry | Mood Disorders

Brief Research Report

Published on 08 Dec 2025

Elevated monocyte-to-lymphocyte ratio, C-reactive protein and further inflammatory parameters as potential biomarkers of suicide risk in bipolar I disorder

in Mood Disorders

Borbála Pethő
Róbert Herold
Diána Simon
Márton Áron Kovács
Tünde Tóth
Noémi Albert
Dóra Hebling
András Sándor Hajnal
Tímea Csulak
Márton Herold

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1648202

582 views

Original Research

Published on 05 Dec 2025

Depressive symptoms and Learning Motivation among Chinese freshmen: a longitudinal study using random intercept cross-lagged panel model and the subgroup analysis of parental educational background

in Mood Disorders

Ye Yu
Ting Yu
Xinfeng Zhang
Li Zhang
Xuejian Su
Xinwei Yu
Yuwei Yang
Ting Pan
Xiaopeng Deng

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1715472

574 views

Original Research

Accepted on 04 Dec 2025

Acceptance and Commitment Therapy for Psychiatric Inpatients Diagnosed with Depression and Insomnia: A Multiple-Baseline Single-Case Study

in Mood Disorders

Zrinka Sosic-Vasic
Max Bergmann
Julia Kroener

Frontiers in Psychiatry

184 views

Original Research

Accepted on 04 Dec 2025

Effect of gender-affirming treatments on depression and anxiety symptoms in transgender people: A retrospective cohort study

in Mood Disorders

Chun Yip Wong
Sze Ting Joanna Ngan
Pak Wing, Calvin Cheng
Wing Ki Tang
Lai Yin Chow
Wai Kwok Kam

Frontiers in Psychiatry

1,408 views

Systematic Review

Published on 04 Dec 2025

Exploring the global prevalence of mood and anxiety disorders in LGBTIQ+ people: A systematic review

in Mood Disorders

Sarah Johnson
Mariia Bogdanova
Laith Alexander
Paul R. A. Stokes

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1662265

978 views

Original Research

Accepted on 03 Dec 2025

Can adaptive hyperactivation result in a positive score on the Mood Disorder Questionnaire? Evidence from a case-control study over a community survey

in Mood Disorders

Michela Atzeni
Michele Fornaro
Massimo Tusconi
Cesar Ivan Aviles Gonzalez
Elisa Cantone
Elisa Pintus
Serdar M Dursun
Antonio E Nardi
Federica Sancassiani
Mauro Giovanni Carta

Frontiers in Psychiatry

221 views

Review

Accepted on 03 Dec 2025

Cardiovascular Disease and Depression: A Bidirectional Relationship and Its Clinical Implications

in Mood Disorders

Jianbo Wu
Zifan Tian
Peng Yu

Frontiers in Psychiatry

240 views

Original Research

Accepted on 02 Dec 2025

Neurocognitive Risk Markers in First-Episode Major Depressive Disorder with Positive Family History: A Large-Scale Case-Control Study

in Mood Disorders

Zhiyong Li
Pan Min
Xialong Cheng
Xulai Zhang
Anzhen Wang
Wenmei Fang
Jianjun Guan
Boyu Zhang

Frontiers in Psychiatry

110 views

Original Research

Accepted on 30 Nov 2025

Proton pump inhibitor use and risk of depression among Sudanese adults: a cross-sectional community-based study

in Mood Disorders

Afnan Alwabili
Saeed Idris
Eman A Alotaibi
Ishag Adam

Frontiers in Psychiatry

120 views

Original Research

Accepted on 28 Nov 2025

Association of Personality Traits with Rumination Improvement Following Cognitive Behavioral Therapy in Major Depression: An Observational Study

in Mood Disorders

Sachiko Noda
Atsuo Nakagawa
Satoshi Umeda
Mizuki Amano
Waka Nogami
SAKAE IHARA
Yuki Kobayashi
Mire Ozawa Kinouchi
Ryo Takemura
Hiroyuki Uchida

Frontiers in Psychiatry

303 views

Original Research

Published on 28 Nov 2025

Reliability and convergent validity of the PHQ-2 for the rapid detection of depressive symptoms in healthcare professionals in Argentina

in Mood Disorders

Nicole Caldichoury
Breiner Morales-Asencio
Juan-Carlos Coronado
Luis Mario Castellanos-Alvarenga
César Quispe-Ayala
Carol Saldías
David Salazar
Daniela Ripoll-Córdoba
Wendy Bada
Juan Martínez

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1652072

1,037 views

Original Research

Published on 28 Nov 2025

Analysis of depression prevalence and associated influencing factors in maintenance hemodialysis patients

in Mood Disorders

Li Cao
Yongming Wu
Ruibo Deng
Xinwen Zhang
Hehua Li
Jiamin Li
Chenyu Liu
Ziyun Zhang
Lin Zhu
Yuanyuan Huang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1682681

688 views

Original Research

Accepted on 27 Nov 2025

Temperament and Character traits and profiles: Impact on Bipolar Disorder risk and onset age

in Mood Disorders

Ioannis Filis
Androniki Naska
ANASTASIA ANTONIOU
Ioanna Constantinidi
Vassiliki Benetou
Panagiotis Ferentinos

Frontiers in Psychiatry

183 views

Mini Review

Published on 26 Nov 2025

Preschool depression: clinical course, risk pathways, and early intervention strategies

in Mood Disorders

Maria Pontillo
Cristina Di Vincenzo
Ilaria Bertoncini
Chiara Pastore
Valeria Villani
Giulia D’Amario
Stefano Vicari

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1685131

1,071 views

Original Research

Accepted on 25 Nov 2025

The Effect of Non-invasive Transcranial Focused Ultrasound for Depression on the Default Mode Network: An Open-label Pilot Trial

in Mood Disorders

Jessica N Schachtner
Jacob F Dahill-Fuchel
Diheng Zhang
Katja E Ehrmann
Christopher R Bawiec
Peter J Hollender
Sarah B Ornellas
Soren D Konecky
Achal S Achrol
John JB Allen

Frontiers in Psychiatry

257 views

Correction

Published on 20 Nov 2025

Correction: Associations between childhood maltreatment and overt aggression in depressed adolescents: the mediating effect of alexithymia and insomnia

in Mood Disorders

Jiawei Wang
Lewei Liu
Sanhua Zhou
Lili Zhao
Qianqian Wu
Tiantian Sun
Nali Zhang
Xuemei Wei
Lei Xia
Feng Zhao

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1734316

456 views

Study Protocol

Published on 20 Nov 2025

Efficacy and safety of laser acupuncture for treating insomnia in major depressive disorder: study protocol for a randomized controlled trial

in Mood Disorders

Qiyue Qiu
Mun Fei Yam
Weiwei Yang
Fei Guo
Chenxi Liu
Mohammad Farris Iman Leong Bin Abdullah
Shichang Yang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1698773

1,138 views

Review

Published on 19 Nov 2025

The impact of nursing intervention on the quality of life of patients with major depressive disorder: a narrative review

in Mood Disorders

Zhizhen Liao
Wene Liu
Luojuan Yin

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1689832

1,296 views

Original Research

Published on 19 Nov 2025

A neural signature for gastrointestinal symptoms in depression: insula-gastric connectivity predicts symptom severity

in Mood Disorders

Li Qi
Ting Zhang
Xiaomin Pan
Zhishun Gao
Jin Li
Yue Yu
Wenjia Wang
Qiang Wei
Jin-Ying Yang
Kai Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1672148

964 views

Original Research

Published on 19 Nov 2025

Factorial invariance of the Spanish version of the PHQ-9 by gender and country in Latin America and the Caribbean

in Mood Disorders

Nicole Caldichoury
Breiner Morales-Asencio
Luis Mario Castellanos-Alvarenga
Juan-Carlos Coronado
César Quispe-Ayala
Daniela Ripoll-Córdoba
Carol Saldías
Wendy Bada
Karen Alcos-Flores
Boris Zurita-Cueva

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1667612

1,319 views

Systematic Review

Published on 19 Nov 2025

Association between atherogenic index of plasma and depression risk: a meta-analysis

in Mood Disorders

Gui-Ling Chen
Gui-Xin Chen
Wei-Tao Wan

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1665118

955 views

Review

Published on 18 Nov 2025

Novel and emerging anesthetic drugs for the treatments of major depression: a comprehensive review of efficacy, mechanism, and outlook

in Mood Disorders

Congyi Li
Zhihui Wang
Xinman Ye
Jiahui Lv
Fangming Chen
Yining Zhang
Jianhua Liu
Xin Li
Jinnian Duan
Ying Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1692751

1,425 views

Original Research

Published on 17 Nov 2025

Sex differences in the prevalence and risk factors of non-suicidal self-injury behaviors among adolescent outpatients with major depressive disorder

in Mood Disorders

Guangyou Lv
Botao Ma
Siyuan Qi
Huimei An

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1599627

841 views

Original Research

Published on 14 Nov 2025

Cognitive functions in euthymic bipolar I and II patients: a cross sectional study

in Mood Disorders

Rifat Serav Ilhan
Safiye Zeynep Tatli
Hilal Demirel
Vesile Şentürk Cankorur

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1659408

923 views

1,671 articles

articles

Elevated monocyte-to-lymphocyte ratio, C-reactive protein and further inflammatory parameters as potential biomarkers of suicide risk in bipolar I disorder

Depressive symptoms and Learning Motivation among Chinese freshmen: a longitudinal study using random intercept cross-lagged panel model and the subgroup analysis of parental educational background

Acceptance and Commitment Therapy for Psychiatric Inpatients Diagnosed with Depression and Insomnia: A Multiple-Baseline Single-Case Study

Effect of gender-affirming treatments on depression and anxiety symptoms in transgender people: A retrospective cohort study

Exploring the global prevalence of mood and anxiety disorders in LGBTIQ+ people: A systematic review

Can adaptive hyperactivation result in a positive score on the Mood Disorder Questionnaire? Evidence from a case-control study over a community survey

Cardiovascular Disease and Depression: A Bidirectional Relationship and Its Clinical Implications

Neurocognitive Risk Markers in First-Episode Major Depressive Disorder with Positive Family History: A Large-Scale Case-Control Study

Proton pump inhibitor use and risk of depression among Sudanese adults: a cross-sectional community-based study

Association of Personality Traits with Rumination Improvement Following Cognitive Behavioral Therapy in Major Depression: An Observational Study

Reliability and convergent validity of the PHQ-2 for the rapid detection of depressive symptoms in healthcare professionals in Argentina

Analysis of depression prevalence and associated influencing factors in maintenance hemodialysis patients

Temperament and Character traits and profiles: Impact on Bipolar Disorder risk and onset age

Preschool depression: clinical course, risk pathways, and early intervention strategies

The Effect of Non-invasive Transcranial Focused Ultrasound for Depression on the Default Mode Network: An Open-label Pilot Trial

Correction: Associations between childhood maltreatment and overt aggression in depressed adolescents: the mediating effect of alexithymia and insomnia

Efficacy and safety of laser acupuncture for treating insomnia in major depressive disorder: study protocol for a randomized controlled trial

The impact of nursing intervention on the quality of life of patients with major depressive disorder: a narrative review

A neural signature for gastrointestinal symptoms in depression: insula-gastric connectivity predicts symptom severity

Factorial invariance of the Spanish version of the PHQ-9 by gender and country in Latin America and the Caribbean

Association between atherogenic index of plasma and depression risk: a meta-analysis

Novel and emerging anesthetic drugs for the treatments of major depression: a comprehensive review of efficacy, mechanism, and outlook

Sex differences in the prevalence and risk factors of non-suicidal self-injury behaviors among adolescent outpatients with major depressive disorder

Cognitive functions in euthymic bipolar I and II patients: a cross sectional study