Frontiers in Systems Biology

Original Research

Published on 30 May 2024

Surface-displayed silicatein-α enzyme in bioengineered E. coli enables biocementation and silica mineralization

in Data and Model Integration

Toriana N. Vigil
Nikolas K. Schwendeman
Melanie L. M. Grogger
Victoria L. Morrison
Margaret C. Warner
Nathaniel B. Bone
Morgan T. Vance
David C. Morris
Kristi McElmurry
Bryan W. Berger

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1377188

2,527 views

Review

Published on 29 Apr 2024

Crosstalking with dendritic cells: a path to engineer advanced T Cell immunotherapy

in Systems and Synthetic Immunology

Sogand Schafer
Kaige Chen
Leyuan Ma

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1372995

3,877 views
1 citation

Original Research

Published on 25 Apr 2024

Elucidating a genomic signature associated with behavioral and executive function after moderate to severe pediatric TBI: a systems biology informed approach

in Integrative Genetics and Genomics

Brad G. Kurowski
Amery Treble-Barna
Valentina Pilipenko
Lisa J. Martin
Anil G. Jegga
Aimee E. Miley
Nanhua Zhang
Anthony Fabio
Ranjit S. Chima
Anna-Lynne R. Adlam

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1293265

1,486 views

Technology and Code

Published on 18 Apr 2024

Context-aware knowledge selection and reliable model recommendation with ACCORDION

in Data and Model Integration

Yasmine Ahmed
Cheryl A. Telmer
Gaoxiang Zhou
Natasa Miskov-Zivanov

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1308292

1,236 views
7 citations

Review

Published on 09 Apr 2024

A review of mathematical modeling of bone remodeling from a systems biology perspective

in Multiscale Mechanistic Modeling

Carley V. Cook
Ariel M. Lighty
Brenda J. Smith
Ashlee N. Ford Versypt

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1368555

5,005 views
9 citations

Original Research

Published on 09 Apr 2024

Forecasting SARS-CoV-2 spike protein evolution from small data by deep learning and regression

in Data and Model Integration

Samuel King
Xinyi E. Chen
Sarah W. S. Ng
Kimia Rostin
Samuel V. Hahn
Tylo Roberts
Janella C. Schwab
Parneet Sekhon
Madina Kagieva
Taylor Reilly

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1284668

3,710 views
3 citations

Perspective

Published on 03 Apr 2024

Is there room in epilepsy for the claustrum?

in Integrative Systems Neuroscience

Glenn D. R. Watson
Stefano Meletti
Anil K. Mahavadi
Pierre Besson
S. Kathleen Bandt
Jared B. Smith

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1385112

1,912 views
1 citation

Original Research

Published on 03 Apr 2024

Intein-mediated thyroid hormone biosensors: towards controlled delivery of hormone therapy

in Translational Systems Biology and In Silico Trials

Quim Martí-Baena
Andreu Pascuet-Fontanet
Tomas Berjaga-Buisan
Miriam Caravaca-Rodríguez
Jaume Puig-Costa-Jussà
Avencia Sanchez-Mejias
Dimitrije Ivančić
Sira Mogas-Díez
Marc Güell
Javier Macia

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1270071

2,556 views

Original Research

Published on 27 Mar 2024

In silico biomarker analysis of the adverse effects of perfluorooctane sulfonate (PFOS) exposure on the metabolic physiology of embryo-larval zebrafish

in Data and Model Integration

Rayna M. Nolen
Lene H. Petersen
Karl Kaiser
Antonietta Quigg
David Hala

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1367562

1,539 views
1 citation

Original Research

Published on 25 Mar 2024

Mathematical modeling of temperature-induced circadian rhythms

in Translational Systems Biology and In Silico Trials

Lingjun Lu
Yannuo Li
Rene Schloss
Ioannis P. Androulakis

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1256398

1,939 views
1 citation

Methods

Published on 21 Mar 2024

A robust ensemble feature selection approach to prioritize genes associated with survival outcome in high-dimensional gene expression data

in Integrative Genetics and Genomics

Phi Le
Xingyue Gong
Leah Ung
Hai Yang
Bridget P. Keenan
Li Zhang
Tao He

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1355595

1,728 views
3 citations

Original Research

Published on 15 Mar 2024

Calcium oscillations in HEK293 cells lacking SOCE suggest the existence of a balanced regulation of IP3 production and degradation

in Multiscale Mechanistic Modeling

Clara Octors
Ryan E. Yoast
Scott M. Emrich
Mohamed Trebak
James Sneyd

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1343006

1,810 views
1 citation

Mini Review

Published on 13 Mar 2024

Computational insights in cell physiology

in Data and Model Integration

Geneviève Dupont
Didier Gonze

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1335885

1,115 views

Original Research

Published on 08 Mar 2024

Uncertainty quantified discovery of chemical reaction systems via Bayesian scientific machine learning

in Translational Systems Biology and In Silico Trials

Emily Nieves
Raj Dandekar
Chris Rackauckas

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1338518

4,490 views
4 citations

Perspective

Published on 08 Mar 2024

Advancing precision medicine therapeutics for Parkinson’s utilizing a shared quantitative systems pharmacology model and framework

in Translational Systems Biology and In Silico Trials

Christopher Denaro
Diane Stephenson
Martijn L. T. M. Müller
Benedetto Piccoli
Karim Azer

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1351555

2,941 views
4 citations

Perspective

Published on 08 Mar 2024

Integrating inverse reinforcement learning into data-driven mechanistic computational models: a novel paradigm to decode cancer cell heterogeneity

in Data and Model Integration

Patrick C. Kinnunen
Kenneth K. Y. Ho
Siddhartha Srivastava
Chengyang Huang
Wanggang Shen
Krishna Garikipati
Gary D. Luker
Nikola Banovic
Xun Huan
Jennifer J. Linderman

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1333760

1,954 views
1 citation