Perspective
Published on 27 Feb 2024
BioModels’ Model of the Year 2023
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2024.1363884
- 4,001 views
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172 articles
articles
Original Research
Published on 15 Feb 2024
Computational inference of chemokine-mediated roles for the vagus nerve in modulating intra- and inter-tissue inflammation
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2024.1266279
- 2,208 views
- 2 citations
Editorial
Published on 02 Feb 2024
Editorial: Combining mechanistic modeling with machine learning to study multiscale biological processes
in Multiscale Mechanistic Modeling
Frontiers in Systems Biology
doi 10.3389/fsysb.2024.1367549
- 2,221 views
- 2 citations
Original Research
Published on 29 Jan 2024
Genome-scale flux balance analysis reveals redox trade-offs in the metabolism of the thermoacidophile Methylacidiphilum fumariolicum under auto-, hetero-and methanotrophic conditions
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2024.1291612
- 6,202 views
- 6 citations
Original Research
Published on 22 Jan 2024
A framework for multi-scale intervention modeling: virtual cohorts, virtual clinical trials, and model-to-model comparisons
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1283341
- 4,286 views
- 15 citations
Original Research
Published on 08 Jan 2024
Metabolic perturbation studies using a Nash Equilibrium model of liver machine perfusion: modeling oxidative stress and effect of glutathione supplementation
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1260315
- 1,638 views
Editorial
Published on 20 Dec 2023
Editorial: Integrative systems biology and big data for agricultural improvement and understanding
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1347323
- 1,473 views
Original Research
Published on 13 Dec 2023
An enhanced transcription factor repressilator that buffers stochasticity and entrains to an erratic external circadian signal
in Multiscale Mechanistic Modeling
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1276734
- 1,929 views
- 2 citations
Hypothesis and Theory
Published on 05 Dec 2023
The development of an ingestible biosensor for the characterization of gut metabolites related to major depressive disorder: hypothesis and theory
in Integrative Systems Microbiology
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1274184
- 7,835 views
- 1 citation
Original Research
Published on 20 Nov 2023
Fine tuning a logical model of cancer cells to predict drug synergies: combining manual curation and automated parameterization
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1252961
- 3,561 views
- 6 citations
Editorial
Published on 29 Sep 2023
Editorial: Virtual patients and digital twins in the systems analysis of drug discovery and development
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1293076
- 2,711 views
- 1 citation
Editorial
Published on 29 Sep 2023
Editorial: Systems biology, women in science 2021/22: translational systems biology and in silico trials
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1293298
- 1,484 views
Editorial
Published on 22 Sep 2023
Editorial: Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1291610
- 2,502 views
- 2 citations
Original Research
Published on 22 Sep 2023
Multilayered safety framework for living diagnostics in the colon
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1240040
- 4,936 views
- 4 citations
Review
Published on 19 Sep 2023
What’s next for computational systems biology?
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1250228
- 10,954 views
- 12 citations
Original Research
Published on 18 Sep 2023
Systems biology platform for efficient development and translation of multitargeted therapeutics
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1229532
- 6,466 views
- 4 citations
Original Research
Published on 23 Aug 2023
In-silico modelling of the mitogen-activated protein kinase (MAPK) pathway in colorectal cancer: mutations and targeted therapy
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1207898
- 3,211 views
- 4 citations
Original Research
Published on 08 Aug 2023
A microbiota-epigenetic circuit controls systematic circadian programs in the gut epithelium
in Integrative Genetics and Genomics
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1175306
- 3,887 views
- 5 citations
Hypothesis and Theory
Published on 25 Jul 2023
Generating synthetic multidimensional molecular time series data for machine learning: considerations
in Multiscale Mechanistic Modeling
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1188009
- 4,818 views
- 13 citations
Original Research
Published on 13 Jul 2023
Alzheimer’s disease protein relevance analysis using human and mouse model proteomics data
in Integrative Systems Neuroscience
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1085577
- 4,333 views
- 7 citations
Original Research
Published on 12 Jul 2023
Contribution of farms to the microbiota in the swine value chain
in Data and Model Integration
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1183868
- 7,796 views
- 5 citations
Original Research
Published on 20 Jun 2023
Application of machine learning in combination with mechanistic modeling to predict plasma exposure of small molecules
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1180948
- 7,865 views
- 24 citations
Methods
Published on 16 Jun 2023
A practical guide for the generation of model-based virtual clinical trials
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1174647
- 13,009 views
- 40 citations
Original Research
Published on 14 Jun 2023
A computational framework for identifying chemical compounds to bind Apolipoprotein E4 for Alzheimer’s disease intervention
in Translational Systems Biology and In Silico Trials
Frontiers in Systems Biology
doi 10.3389/fsysb.2023.1188430
- 4,189 views
- 3 citations