Frontiers in Toxicology

Original Research

Published on 22 Jul 2024

Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish

in Environmental Toxicology

Yvonne Rericha
Lindsey St. Mary
Lisa Truong
Ryan McClure
J. Kainalu Martin
Scott W. Leonard
Preethi Thunga
Michael T. Simonich
Katrina M. Waters
Jennifer A. Field

Frontiers in Toxicology

doi 10.3389/ftox.2024.1425537

7,501 views
15 citations

Technology and Code

Published on 22 Jul 2024

Transforming environmental health datasets from the comparative toxicogenomics database into chord diagrams to visualize molecular mechanisms

in Computational Toxicology and Informatics

Brent Wyatt
Allan Peter Davis
Thomas C. Wiegers
Jolene Wiegers
Sakib Abrar
Daniela Sciaky
Fern Barkalow
Melissa Strong
Carolyn J. Mattingly

Frontiers in Toxicology

doi 10.3389/ftox.2024.1437884

3,130 views
12 citations

Perspective

Published on 19 Jul 2024

Safety of titanium dioxide (E171) as a food additive for humans

in Nanotoxicology

David B. Warheit

Frontiers in Toxicology

doi 10.3389/ftox.2024.1333746

15,220 views
10 citations

Correction

Published on 19 Jul 2024

Corrigendum: Applying new approach methodologies to assess next-generation tobacco and nicotine products

in In Vitro Toxicology

David Thorne
Damian McHugh
Liam Simms
K. Monica Lee
Hitoshi Fujimoto
Sara Moses
Marianna Gaca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1460271

1,482 views

Review

Published on 18 Jul 2024

Per- and poly-fluoroalkyl substances (PFAS) effects on lung health: a perspective on the current literature and future recommendations

in Environmental Toxicology

Megan E. Solan
Jin-Ah Park

Frontiers in Toxicology

doi 10.3389/ftox.2024.1423449

13,324 views
17 citations

Review

Published on 17 Jul 2024

Unleashing the potential of cell painting assays for compound activities and hazards prediction

in In Vitro Toxicology

Floriane Odje
David Meijer
Elena von Coburg
Justin J. J. van der Hooft
Sebastian Dunst
Marnix H. Medema
Andrea Volkamer

Frontiers in Toxicology

doi 10.3389/ftox.2024.1401036

7,946 views
5 citations

Original Research

Published on 15 Jul 2024

Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions

in Environmental Toxicology

Tea Pihlaja
Timo Oksanen
Netta Vinkvist
Tiina Sikanen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1406942

2,914 views
3 citations

Methods

Published on 15 Jul 2024

sendigR: an R package to leverage the value of CDISC SEND datasets for cross-study analysis

in Computational Toxicology and Informatics

K. Snyder
C. M. Sabbir Ahmed
Md Yousuf Ali
S. Butler
Michael DeNieu
W. Houser
B. Paisley
M. Rosentreter
W. Wang
B. Larsen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1392686

3,765 views
2 citations

Original Research

Published on 10 Jul 2024

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

in Immunotoxicology

Lorena Ndreu
Josefine Carlsson
David J. Ponting
Ida B. Niklasson
E. Johanna L. Stéen
Lukas McHugh
Niamh M. O’Boyle
Kristina Luthman
Ann-Therese Karlberg
Isabella Karlsson

Frontiers in Toxicology

doi 10.3389/ftox.2024.1398852

5,756 views
1 citation

Editorial

Published on 02 Jul 2024

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

in Computational Toxicology and Informatics

Kan Shao
Chao Ji
Bernard Gadagbui

Frontiers in Toxicology

doi 10.3389/ftox.2024.1440229

3,510 views
1 citation

Original Research

Published on 01 Jul 2024

Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells

in Nanotoxicology

Asuka Nishida
Yuka Sawada
Rion Arai
Naoki Ishibashi
Miho Suzuo
Akiko Ohno
Takao Ashikaga
Kazutoshi Iijima

Frontiers in Toxicology

doi 10.3389/ftox.2024.1293147

2,717 views
2 citations

Original Research

Published on 13 Jun 2024

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

in In Vitro Toxicology

Fiona Chapman
Luuk de Haan
Linda Gijzen
Wouter Strijker
Edgar Trelles Sticken
Sarah Jean Pour
Roman Wieczorek
Florian Haberstroh
Sandra Otte
Thomas Nahde

Frontiers in Toxicology

doi 10.3389/ftox.2024.1395670

5,814 views
1 citation

Review

Published on 13 Jun 2024

Applying new approach methodologies to assess next-generation tobacco and nicotine products

in In Vitro Toxicology

David Thorne
Damian McHugh
Liam Simms
K. Monica Lee
Hitoshi Fujimoto
Sara Moses
Marianna Gaca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1376118

7,315 views
5 citations

Policy and Practice Reviews

Published on 12 Jun 2024

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

in Regulatory Toxicology

Amber Goetz
Natalia Ryan
Alaina Sauve-Ciencewicki
Caleb C. Lord
Gina M. Hilton
Douglas C. Wolf

Frontiers in Toxicology

doi 10.3389/ftox.2024.1394361

3,405 views
3 citations

Editorial

Published on 07 Jun 2024

Editorial: Linking environmental exposure to toxicants and chronic disease

in Developmental and Reproductive Toxicology

David R. Wallace
Aleksandra Buha Đorđević

Frontiers in Toxicology

doi 10.3389/ftox.2024.1430316

1,637 views

Original Research

Published on 05 Jun 2024

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

in Environmental Toxicology

Archana Hari
Mohamed Diwan M. AbdulHameed
Michele R. Balik-Meisner
Deepak Mav
Dhiral P. Phadke
Elizabeth H. Scholl
Ruchir R. Shah
Warren Casey
Scott S. Auerbach
Anders Wallqvist

Frontiers in Toxicology

doi 10.3389/ftox.2024.1390196

7,200 views
15 citations

Systematic Review

Published on 30 May 2024

Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis

in Developmental and Reproductive Toxicology

Roland Eghoghosoa Akhigbe
Precious Adeoye Oyedokun
Tunmise Maryanne Akhigbe
Suliat Adenike
Ayoola Abimbola Oladipo
Jennifer Rose Hughes

Frontiers in Toxicology

doi 10.3389/ftox.2024.1395010

3,008 views
6 citations

Review

Published on 30 May 2024

Global challenges in aging: insights from comparative biology and one health

in Environmental Toxicology

Mary Ann Ottinger
Jacquelyn K. Grace
Terri J. Maness

Frontiers in Toxicology

doi 10.3389/ftox.2024.1381178

3,022 views
3 citations

Perspective

Published on 28 May 2024

The DaNa projects: public communication of (nano)material safety data—from conspiracy theories to study quality

in Nanotoxicology

Dana Kühnel
Harald F. Krug
Christoph Steinbach
Katja Nau

Frontiers in Toxicology

doi 10.3389/ftox.2024.1382458

2,500 views

Perspective

Published on 23 May 2024

ICH S1 prospective evaluation study and weight of evidence assessments: commentary from industry representatives

in Regulatory Toxicology

John L. Vahle
Joe Dybowski
Michael Graziano
Shigeru Hisada
Jose Lebron
Thomas Nolte
Ronald Steigerwalt
Kenjiro Tsubota
Frank D. Sistare

Frontiers in Toxicology

doi 10.3389/ftox.2024.1377990

4,907 views
4 citations

Original Research

Published on 16 May 2024

Dechloranes and chlorinated paraffins in sediments and biota of two subarctic lakes

in Environmental Toxicology

Aline Arriola
Insam Al Saify
Nicholas A. Warner
Dorte Herzke
Mikael Harju
Per-Arne Amundsen
Anita Evenset
Claudia Möckel
Ingjerd S. Krogseth

Frontiers in Toxicology

doi 10.3389/ftox.2024.1298231

2,230 views
1 citation

Original Research

Published on 10 May 2024

The application of natural language processing for the extraction of mechanistic information in toxicology

in Computational Toxicology and Informatics

Marie Corradi
Thomas Luechtefeld
Alyanne M. de Haan
Raymond Pieters
Jonathan H. Freedman
Tamara Vanhaecke
Mathieu Vinken
Marc Teunis

Frontiers in Toxicology

doi 10.3389/ftox.2024.1393662

16,002 views
8 citations

Case Report

Published on 09 May 2024

Asystole in a young child with tetrahydrocannabinol overdose: a case report and review of literature

in Clinical Toxicology

Mats Steffi Jennifer Masilamani
Rebecca Leff
Yu Kawai

Frontiers in Toxicology

doi 10.3389/ftox.2024.1371651

2,980 views
1 citation

Review

Published on 07 May 2024

Impact of dioxins on reproductive health in female mammals

in Developmental and Reproductive Toxicology

Nour Aldeli
Denis Murphy
Abdulsamie Hanano

Frontiers in Toxicology

doi 10.3389/ftox.2024.1392257

5,294 views
14 citations

618 articles

articles

Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish

Transforming environmental health datasets from the comparative toxicogenomics database into chord diagrams to visualize molecular mechanisms

Safety of titanium dioxide (E171) as a food additive for humans

Corrigendum: Applying new approach methodologies to assess next-generation tobacco and nicotine products

Per- and poly-fluoroalkyl substances (PFAS) effects on lung health: a perspective on the current literature and future recommendations

Unleashing the potential of cell painting assays for compound activities and hazards prediction

Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions

sendigR: an R package to leverage the value of CDISC SEND datasets for cross-study analysis

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

Applying new approach methodologies to assess next-generation tobacco and nicotine products

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

Editorial: Linking environmental exposure to toxicants and chronic disease

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis

Global challenges in aging: insights from comparative biology and one health

The DaNa projects: public communication of (nano)material safety data—from conspiracy theories to study quality

ICH S1 prospective evaluation study and weight of evidence assessments: commentary from industry representatives

Dechloranes and chlorinated paraffins in sediments and biota of two subarctic lakes

The application of natural language processing for the extraction of mechanistic information in toxicology

Asystole in a young child with tetrahydrocannabinol overdose: a case report and review of literature

Impact of dioxins on reproductive health in female mammals