Frontiers in Toxicology

Original Research

Published on 15 Jul 2022

“In Litero” Screening: Retrospective Evaluation of Clinical Evidence to Establish a Reference List of Human Chemical Respiratory Sensitizers

in Regulatory Toxicology

Jessica Ponder
Ramya Rajagopal
Madhuri Singal
Nancy Baker
Grace Patlewicz
Erwin Roggen
Stella Cochrane
Kristie Sullivan

Frontiers in Toxicology

doi 10.3389/ftox.2022.916370

4,079 views
13 citations

Review

Published on 06 Jul 2022

Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events

in Regulatory Toxicology

Shihori Tanabe
Jason O’Brien
Knut Erik Tollefsen
Youngjun Kim
Vinita Chauhan
Carole Yauk
Elizabeth Huliganga
Ruthann A. Rudel
Jennifer E. Kay
Jessica S. Helm

Frontiers in Toxicology

doi 10.3389/ftox.2022.887135

6,499 views
25 citations

Review

Published on 01 Jul 2022

Think Beyond Particle Cytotoxicity: When Self-Cellular Components Released After Immunogenic Cell Death Explain Chronic Disease Development

in Immunotoxicology

Riccardo Leinardi
Chiara Longo Sanchez-Calero
François Huaux

Frontiers in Toxicology

doi 10.3389/ftox.2022.887228

4,628 views
7 citations

Brief Research Report

Published on 01 Jul 2022

Toxicological Impact and in Vivo Tracing of Rhodamine Functionalised ZIF-8 Nanoparticles

in Nanotoxicology

Prateek Goyal
Pushpanjali Soppina
Superb K. Misra
Eugenia Valsami-Jones
Virupakshi Soppina
Swaroop Chakraborty

Frontiers in Toxicology

doi 10.3389/ftox.2022.917749

3,554 views
7 citations

Perspective

Published on 30 Jun 2022

Mentoring and Supporting Our Next Generation of Women Toxicologists

in Developmental and Reproductive Toxicology

Hollie I. Swanson

Frontiers in Toxicology

doi 10.3389/ftox.2022.920664

3,225 views
3 citations

Original Research

Published on 29 Jun 2022

Combination of Autophagy Selective Therapeutics With Doxil: An Assessment of Pathological Toxicity

in Immunotoxicology

Kristi L. Helke
Radhika R. Gudi
Chenthamarakshan Vasu
Joe R. Delaney

Frontiers in Toxicology

doi 10.3389/ftox.2022.937150

3,596 views
1 citation

Brief Research Report

Published on 27 Jun 2022

Evaluation of Transcriptomic Responses in Livers of Mice Exposed to the Short-Chain PFAS Compound HFPO-DA

in Toxicogenomics

Melissa M. Heintz
Grace A. Chappell
Chad M. Thompson
Laurie C. Haws

Frontiers in Toxicology

doi 10.3389/ftox.2022.937168

4,933 views
19 citations

Review

Published on 24 Jun 2022

Management of Severe Traumatic Brain Injury in Pediatric Patients

in Neurotoxicology

Austin Lui
Kevin K. Kumar
Gerald A. Grant

Frontiers in Toxicology

doi 10.3389/ftox.2022.910972

34,846 views
18 citations

Technology and Code

Published on 22 Jun 2022

Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research

in Computational Toxicology and Informatics

Kyle Roell
Lauren E. Koval
Rebecca Boyles
Grace Patlewicz
Caroline Ring
Cynthia V. Rider
Cavin Ward-Caviness
David M. Reif
Ilona Jaspers
Rebecca C. Fry

Frontiers in Toxicology

doi 10.3389/ftox.2022.893924

5,502 views
8 citations

Perspective

Published on 21 Jun 2022

Impact of Established and Emerging Software Tools on the Metabolite Identification Landscape

in Computational Toxicology and Informatics

Anne Marie E. Smith
Kiril Lanevskij
Andrius Sazonovas
Jesse Harris

Frontiers in Toxicology

doi 10.3389/ftox.2022.932445

4,561 views
4 citations

Editorial

Published on 21 Jun 2022

Editorial: Role of the Aryl Hydrocarbon Receptor in Immune Modulation

in Immunotoxicology

Barbara L. F. Kaplan
Carolyn J. Baglole
Courtney E. W. Sulentic

Frontiers in Toxicology

doi 10.3389/ftox.2022.941665

2,080 views
1 citation

Review

Published on 20 Jun 2022

Candidate Proficiency Test Chemicals to Address Industrial Chemical Applicability Domains for in vitro Human Cytochrome P450 Enzyme Induction

in Regulatory Toxicology

Miriam Naomi Jacobs
Barbara Kubickova
Eugene Boshoff

Frontiers in Toxicology

doi 10.3389/ftox.2022.880818

5,324 views
6 citations

Original Research

Published on 17 Jun 2022

A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System

in In Vitro Toxicology

Arunima Sengupta
Nuria Roldan
Mirjam Kiener
Laurène Froment
Giulia Raggi
Theo Imler
Lea de Maddalena
Aude Rapet
Tobias May
Patrick Carius

Frontiers in Toxicology

doi 10.3389/ftox.2022.840606

14,801 views
41 citations

Review

Published on 15 Jun 2022

Safety and Toxicity Implications of Multifunctional Drug Delivery Nanocarriers on Reproductive Systems In Vitro and In Vivo

in Developmental and Reproductive Toxicology

Anas Ahmad

Frontiers in Toxicology

doi 10.3389/ftox.2022.895667

4,810 views
21 citations

Original Research

Published on 15 Jun 2022

Mapping Adverse Outcome Pathways for Kidney Injury as a Basis for the Development of Mechanism-Based Animal-Sparing Approaches to Assessment of Nephrotoxicity

in In Vitro Toxicology

Angela Mally
Sebastian Jarzina

Frontiers in Toxicology

doi 10.3389/ftox.2022.863643

3,583 views
6 citations

Methods

Published on 08 Jun 2022

Thymidine Kinase+/− Mammalian Cell Mutagenicity Assays for Assessment of Nanomaterials

in Nanotoxicology

Tao Chen
Maria Dusinska
Rosalie Elespuru

Frontiers in Toxicology

doi 10.3389/ftox.2022.864753

4,833 views
4 citations