Frontiers in Toxicology

Original Research

Accepted on 04 Nov 2025

Role of bisphenol A in the aberrant activation of ionotropic glutamate transporters in the cerebral cortex and altered behavioral responses in C57BL/6J mice

in Neurotoxicology

Jasim Khan
Kajal Kamble
Dr Mohammad Waseem
Suhel Parvez
Basu Dev Banerjee
Sarika Gupta
Sheikh Raisuddin

Frontiers in Toxicology

246 views

Original Research

Published on 03 Nov 2025

Comprehensive methodology for standardized ecotoxicological assessment of TiO2-based sunscreen leachates in aquatic environment

in Environmental Toxicology

Roberta Nugnes
Giulia De Negri Atanasio
Elisabetta Perata
Erica Lertora
Lorenzo Dondero
Federica Robino
Francesca Tardanico
Cristina Capelli
Fabio Ghioni
Tania Cai

Frontiers in Toxicology

doi 10.3389/ftox.2025.1686954

1,256 views

Review

Accepted on 30 Oct 2025

Effect of Atrazine on the HPG and HPA Axes and Steroidogenic Pathways in Females: Relevance for Carcinogenicity to Reproductive Function and Carcinogenicity

in Developmental and Reproductive Toxicology

Ralph Cooper
James William Simpkins
Charles Breckenridge

Frontiers in Toxicology

Original Research

Published on 30 Oct 2025

Montmorillonite-based essential oil carrier and its effects on non-target species: an environmental perspective on its risk assessment

in Environmental Toxicology

Sofia Machado
Catarina Ganilho
Tatiana Andreani
Rose Marie O. F. Sousa
Artur Ribeiro
Ruth Pereira

Frontiers in Toxicology

doi 10.3389/ftox.2025.1696913

891 views

Review

Published on 30 Oct 2025

Developing an approach for evaluating the cardiotoxic potential of botanicals

in In Vitro Toxicology

Julie Krzykwa
Hemantkumar S. Chaudhari
Andre Monteiro Da Rocha
Matthias Gossmann
Peter Hoffmann
Yaser Khokhar
Nathan Meyer
Jin-Young K. Park
Robert Sprando
Ravi Vaidyanathan

Frontiers in Toxicology

doi 10.3389/ftox.2025.1646044

1,908 views
1 citation

Original Research

Published on 30 Oct 2025

Alternatives to animal-derived extracellular matrix hydrogels? An explorative study with HepaRG cells in animal-free hydrogels under static and dynamic culture conditions

in In Vitro Toxicology

Katharina S. Nitsche
Paul L. Carmichael
Sophie Malcomber
Iris Müller
Hans Bouwmeester

Frontiers in Toxicology

doi 10.3389/ftox.2025.1649393

2,013 views
1 citation

Original Research

Accepted on 28 Oct 2025

Development and validation of a bedside prognostic model for in-hospital mortality in acute diquat poisoning

in Clinical Toxicology

Ye Zhang
Xian Chen
Kang Liu
Haike Du
Xiaoming Jiang
Yingmin Ma

Frontiers in Toxicology

218 views

Original Research

Published on 28 Oct 2025

A toxicological assessment of Hericium erinaceus (Lion’s mane) and Trametes versicolor (Turkey tail) mushroom powders

in Food and Nutritional Toxicology

Kritika Mahadevan
Julie Daoust
Thomas Brendler
Ankit Chaudhary
Alimuddin Saifi
Vipin Kumar Garg

Frontiers in Toxicology

doi 10.3389/ftox.2025.1651442

3,086 views

Original Research

Published on 20 Oct 2025

Toxicological and nutritional evaluation of plant cell cultures from scurvy grass (Cochlearia danica) and rowan (Sorbus aucuparia)

in Food and Nutritional Toxicology

Felicianna
Ho Lam Cheung
Emily Kwun Kwan Lo
Fangfei Zhang
Hoi Kit Matthew Leung
Marsena Jasiel Ismaiah
Natalia Rosa-Sibakov
Valeria Iannone
Carlos Gómez-Gallego
Marjukka Kolehmainen

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655489

1,460 views

Original Research

Published on 20 Oct 2025

Toxicological effects of sublethal microcystin-LR exposure in Labeo rohita: histopathological, ultrastructural, immunological, and biochemical impairments

in Environmental Toxicology

Snatashree Mohanty
Anirban Paul
K. V. Rajendran
Gayatri Tripathi
Pratap Chandra Das
Pramoda Kumar Sahoo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1658995

1,311 views

Original Research

Published on 17 Oct 2025

Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish

in Neurotoxicology

Lindsey St. Mary
Ryan McClure
Lisa Truong
Steven J. Carrell
Katrina M. Waters
Robyn L. Tanguay

Frontiers in Toxicology

doi 10.3389/ftox.2025.1675060

1,415 views

Original Research

Published on 17 Oct 2025

Danger on the plate: human health risks derived from the consumption of angular angelshark (Squatina guggenheim) meat in southeastern Brazil

in Food and Nutritional Toxicology

Amanda Pontes Lopes
Rebeca Dias de Souza Coutinho
Tatiana Dillenburg Saint’Pierre
Rachel Ann Hauser-Davis

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645858

1,242 views

Original Research

Published on 15 Oct 2025

A short-term sublethal oral exposure to microcystin-LR disrupts cecal microbiome homeostasis in mallard

in Environmental Toxicology

Serguei V. Drovetski
Valerie I. Shearn-Bochsler
Erik K. Hofmeister
Natalie K. Karouna-Renier
Robert J. Dusek

Frontiers in Toxicology

doi 10.3389/ftox.2025.1634241

1,024 views

Original Research

Published on 14 Oct 2025

Intravenously administered iron oxide nanoparticles with different coatings reversibly perturb immune cells in peripheral blood without inducing toxicity in mice

in Nanotoxicology

Preethi Korangath
Chun-Ting Yang
Sean Healy
Cordula Grüttner
Kathleen Gabrielson
Robert Ivkov

Frontiers in Toxicology

doi 10.3389/ftox.2025.1673416

1,418 views

Perspective

Published on 13 Oct 2025

Refining the safety assessment of newly expressed proteins in GMOs

in In Vitro Toxicology

Elena Sánchez-Brunete
Arianna Ferrari
F. Javier Moreno
Tilemachos Goumperis
Michele Ardizzone
Reinhilde Schoonjans
Ian Dewhurst
Ivan Dimitrov
Michelle M. Epstein
Frits Koning

Frontiers in Toxicology

doi 10.3389/ftox.2025.1679506

1,877 views

Original Research

Published on 08 Oct 2025

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

in Regulatory Toxicology

Jessica Ryman
Richard A. Becker

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657708

1,588 views

Review

Published on 07 Oct 2025

Advancing human health risk assessment: the role of new approach methodologies

in Computational Toxicology and Informatics

Deepika Deepika
Kanchan Bharti
Shubh Sharma
Saurav Kumar
Rajesh Kumar Pathak
Judit Biosca Brull
Oscar Sabuz
Silvia García Vilana
Vikas Kumar

Frontiers in Toxicology

doi 10.3389/ftox.2025.1632941

2,647 views
3 citations

Original Research

Published on 03 Oct 2025

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays

in In Vitro Toxicology

Agnes L. Karmaus
Alex Charlton

Frontiers in Toxicology

doi 10.3389/ftox.2025.1682439

1,107 views

Review

Published on 03 Oct 2025

Pesticides, an urgent challenge to global environmental health and planetary boundaries

in Developmental and Reproductive Toxicology

Laura N. Vandenberg
Elise J. Pierce
Rachel M. Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

3,088 views
1 citation

Original Research

Published on 01 Oct 2025

Hospital admissions for acute drug poisoning in adults and children: a 7-year retrospective analysis of hospital discharges at a tertiary center

in Clinical Toxicology

Daniel Wang
Lina Camacho-Arteaga
Rosario Muñoz Gallarín
Immaculada Danés
Antònia Agustí Escasany

Frontiers in Toxicology

doi 10.3389/ftox.2025.1672470

1,599 views

Original Research

Published on 01 Oct 2025

Proliferation and metabolic activity of the Atlantic sturgeon cell line AOXlar7y under short-term serum-reduced conditions, and the effect of stimulation with growth factors and cytokines

in In Vitro Toxicology

Valeria Di Leonardo
Julia Brenmoehl
Heike Wanka
Bianka Grunow

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636776

1,496 views

Original Research

Published on 01 Oct 2025

Promoting ethical and reproducible cell culture: implementing animal-free alternatives to teaching in molecular and cell biology

in In Vitro Toxicology

Alexandra Nessar
Viola Röhrs
Mathias Ziersch
Ahmed S. M. Ali
Julia Moradi
Anke Kurreck
Johanna Berg
Jens Kurreck

Frontiers in Toxicology

doi 10.3389/ftox.2025.1670513

4,278 views
1 citation

Original Research

Published on 30 Sep 2025

Acetaldehyde and methylglyoxal: comparative analysis of toxic electronic cigarette degradation products in 3D and 2D exposure systems using human bronchial epithelial models

in In Vitro Toxicology

Man Wong
Teresa Martinez
Nathan Hendricks
Prue Talbot

Frontiers in Toxicology

doi 10.3389/ftox.2025.1624794

4,023 views

Original Research

Published on 29 Sep 2025

In Vitro analysis of the effect of mono-(2-ethylhexyl) phthalate (MEHP) exposure on macrophage inflammatory responses in relationship to Leydig cell steroid production

in Developmental and Reproductive Toxicology

Akhil Adla
Allison Lunney
Barry Zirkin
Kassim Traore

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636395

1,413 views