Frontiers in Toxicology

Original Research

Published on 15 May 2025

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke

in In Vitro Toxicology

Sakuya Ichikawa
Shugo Muratani
Keigo Sano
Kazuo Erami
Akina Mori
Risa Matsumoto
Shigeaki Ito

Frontiers in Toxicology

doi 10.3389/ftox.2025.1564857

1,975 views
1 citation

Editorial

Published on 15 May 2025

Editorial: Legacy & emerging contaminants in the aquatic environment—bridging knowledge, policy, and future

in Environmental Toxicology

Abdul Qadeer
Mengyang Liu
Sanjeeb Mohapatra
Racliffe Weng Seng Lai

Frontiers in Toxicology

doi 10.3389/ftox.2025.1611852

2,576 views

Original Research

Published on 15 May 2025

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

in Computational Toxicology and Informatics

Shigeaki Ito
Sakuya Ichikawa
Risa Matsumoto
Shugo Muratani
Keigo Sano
Akina Mori
Kazuo Erami

Frontiers in Toxicology

doi 10.3389/ftox.2025.1564864

1,805 views

Mini Review

Published on 14 May 2025

Optimizing Wnt activation in fetal calf serum (FCS)-free organoid expansion media

in Regulatory Toxicology

Esther J. M. Liefting
Jeffrey J. Bajramovic

Frontiers in Toxicology

doi 10.3389/ftox.2025.1504469

2,432 views
1 citation

Case Report

Published on 09 May 2025

Case report: Treatment of severe phorate poisoning

in Clinical Toxicology

Wang Kunlun
Yuan Jun
Xu Shiming
Shen Jie
Gao Mingqiang
Zhang Yuxia
Mo Weichun

Frontiers in Toxicology

doi 10.3389/ftox.2025.1581362

3,246 views

Opinion

Published on 08 May 2025

Raising awareness of riverine populations in the Brazilian Amazon about MeHg intoxication in APOE4 carriers: cardiovascular risk and potential benefit of native selenium diets

in Food and Nutritional Toxicology

Camila G. M. Carvalho
Patrícia Marçal Da Costa
Luana M. Rocha Souza
Vitória K. Félix Monteiro
Jacqueline I. Alvarez-leite
Maria Elena Crespo-Lopez
Reinaldo B. Oriá

Frontiers in Toxicology

doi 10.3389/ftox.2025.1571658

2,128 views

Original Research

Published on 08 May 2025

Rat embryonic stem cell-based in vitro testing platform for mammalian embryo toxicology at pre- and post-implantation stages

in Developmental and Reproductive Toxicology

Corinne Quadalti
Marzia Moretti
Fabio Ferrazzi
Laura Calzà
Luciana Giardino
Vito Antonio Baldassarro

Frontiers in Toxicology

doi 10.3389/ftox.2025.1561386

2,584 views

Editorial

Published on 06 May 2025

Editorial: Women in nanotoxicology 2023–2024

in Nanotoxicology

Iseult Lynch
Ilika Ghosh

Frontiers in Toxicology

doi 10.3389/ftox.2025.1599767

1,659 views

Original Research

Published on 01 May 2025

Nutrients and phytochemicals characterisations, acute and sub-acute oral toxicity studies of BobyGuard C, a polyherbal nutraceutical with anti-breast cancer properties

in Food and Nutritional Toxicology

Borelle Mafogang
Roger Ponka
Joseph Ngakou Mukam
Elie Fokou

Frontiers in Toxicology

doi 10.3389/ftox.2025.1598185

2,267 views
1 citation

Original Research

Published on 29 Apr 2025

Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns

in Environmental Toxicology

Antonin Ambroz
Jiri Klema
Andrea Rossnerova
Alena Milcova
Anna Pastorkova
Jana Pulkrabova
Ondrej Parizek
Veronika Gomersall
Tomas Gramblicka
Jaroslav Zelenka

Frontiers in Toxicology

doi 10.3389/ftox.2025.1572486

2,321 views
1 citation

Original Research

Published on 22 Apr 2025

Critical values for dimensional parameters of mesotheliomagenic mineral fibers: evidence from the dimensions and rigidity of MWCNT

in Nanotoxicology

Ann G. Wylie
Andrey A. Korchevskiy

Frontiers in Toxicology

doi 10.3389/ftox.2025.1568513

2,136 views
4 citations

Brief Research Report

Published on 22 Apr 2025

Elucidating the mechanistic relationships between peroxisome proliferator–activated receptors and hepatic fibrosis using the ROBOKOP knowledge graph

in Computational Toxicology and Informatics

Karamarie Fecho
Nyssa Tucker
Jon-Michael Beasley
Scott S. Auerbach
Chris Bizon
Alexander Tropsha

Frontiers in Toxicology

doi 10.3389/ftox.2025.1549268

1,956 views
1 citation

Original Research

Published on 17 Apr 2025

Developing a predictive model for blood-brain-barrier permeability to explore relevance of in vitro neurotoxicity data for in vivo risk assessment

in Computational Toxicology and Informatics

Siena E. Illa
Yumei Feng Earley
Li Li
Dingsheng Li

Frontiers in Toxicology

doi 10.3389/ftox.2025.1535112

3,672 views
2 citations

Original Research

Published on 16 Apr 2025

Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus)

in Environmental Toxicology

Bingbu Li
Guixing Wang
Xinyu Zheng
Mingyang Liu
Yucong Yang
Yuqin Ren
Yitong Zhang
Yufeng Liu
Zhongwei He
Jiangong Ren

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560192

10,111 views
1 citation

Mini Review

Published on 15 Apr 2025

Developing a feasible fast-track testing method for developmental neurotoxicity studies: alternative model for risk assessment of micro- and nanoplastics

in Environmental Toxicology

Xian Wu
TinChung Leung
Dereje D. Jima
Majemite Iyangbe
John Bang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1567225

2,966 views
2 citations

Editorial

Published on 14 Apr 2025

Editorial: “Unravelling micro-/nano-plastics toxicity profiling: can we link associated effects to intrinsic characteristics?”

in Environmental Toxicology

Sebastian Beggel
Valentina Helen Pauna
Vanessa Modesto
Marisa Sárria Pereira de Passos

Frontiers in Toxicology

doi 10.3389/ftox.2025.1605402

1,767 views

Review

Published on 14 Apr 2025

Acute cannabis intoxication among the paediatric population

in Clinical Toxicology

Ginevra Malta
Giuseppe Davide Albano
Gianluca Lavanco
Anna Brancato
Carla Cannizzaro
Antonina Argo
Simona Contorno
Fulvio Plescia
Stefania Zerbo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1558721

7,665 views
4 citations

Systematic Review

Published on 09 Apr 2025

Lupin poisoning: a review

in Clinical Toxicology

Meye Bloothooft
Pien Cremers
Sükriye Güven
Stijn J. Stoutjesdijk
Mara Jiron
Mark Wessel
Marcel A. G. Van Der Heyden

Frontiers in Toxicology

doi 10.3389/ftox.2025.1547535

7,321 views
4 citations

Original Research

Published on 01 Apr 2025

Promising protective potential of MiR-103a-3p against polystyrene microplastic neurotoxicity in rats

in Neurotoxicology

Leila Mohammadi
Tourandokht Baluchnejadmojarad
Mina Goudarzi
Vahid Khodashenas
Roya Khoshravesh
Mehrdad Roghani

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560980

3,561 views
4 citations

Original Research

Published on 26 Mar 2025

Advancing humanized 3D tumor modeling using an open access xeno-free medium

in In Vitro Toxicology

Atena Malakpour-Permlid
Manuel Marcos Rodriguez
Kinga Zór
Anja Boisen
Stina Oredsson

Frontiers in Toxicology

doi 10.3389/ftox.2025.1529360

3,404 views
3 citations

Original Research

Published on 21 Mar 2025

Toxic effects of Lepidium sativum seed fixed oil on Wistar albino rats in acute and subacute toxicity models

in Food and Nutritional Toxicology

Teshome Gebremeskel Aragie
Kaleab Asres
Wondwossen Ergete
Samual Woldekidan
Sileshi Degu
Abiy Abebe
Worku Gemechu
Derso Furgasa
Girma Seyoum

Frontiers in Toxicology

doi 10.3389/ftox.2025.1535597

2,488 views
1 citation

Original Research

Published on 17 Mar 2025

Modeling marine microplastic emissions in Life Cycle Assessment: characterization factors for biodegradable polymers and their application in a textile case study

in Environmental Toxicology

Felicitas Pellengahr
Elena Corella-Puertas
Valérie Mattelin
Nadim Saadi
Francesca Bertella
Anne-Marie Boulay
Yvonne van der Meer

Frontiers in Toxicology

doi 10.3389/ftox.2025.1494220

5,369 views
6 citations

Editorial

Published on 17 Mar 2025

Editorial: Global excellence in toxicology: Asia, Australia and New Zealand

in Nanotoxicology

Yongning Wu

Frontiers in Toxicology

doi 10.3389/ftox.2025.1584009

1,556 views

Original Research

Published on 14 Mar 2025

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS

in Regulatory Toxicology

L. Brunken
A. Vieira Silva
M. Öberg

Frontiers in Toxicology

doi 10.3389/ftox.2025.1525089

2,380 views

618 articles

articles

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke

Editorial: Legacy & emerging contaminants in the aquatic environment—bridging knowledge, policy, and future

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

Optimizing Wnt activation in fetal calf serum (FCS)-free organoid expansion media

Case report: Treatment of severe phorate poisoning

Raising awareness of riverine populations in the Brazilian Amazon about MeHg intoxication in APOE4 carriers: cardiovascular risk and potential benefit of native selenium diets

Rat embryonic stem cell-based in vitro testing platform for mammalian embryo toxicology at pre- and post-implantation stages

Editorial: Women in nanotoxicology 2023–2024

Nutrients and phytochemicals characterisations, acute and sub-acute oral toxicity studies of BobyGuard C, a polyherbal nutraceutical with anti-breast cancer properties

Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns

Critical values for dimensional parameters of mesotheliomagenic mineral fibers: evidence from the dimensions and rigidity of MWCNT

Elucidating the mechanistic relationships between peroxisome proliferator–activated receptors and hepatic fibrosis using the ROBOKOP knowledge graph

Developing a predictive model for blood-brain-barrier permeability to explore relevance of in vitro neurotoxicity data for in vivo risk assessment

Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus)

Developing a feasible fast-track testing method for developmental neurotoxicity studies: alternative model for risk assessment of micro- and nanoplastics

Editorial: “Unravelling micro-/nano-plastics toxicity profiling: can we link associated effects to intrinsic characteristics?”

Acute cannabis intoxication among the paediatric population

Lupin poisoning: a review

Promising protective potential of MiR-103a-3p against polystyrene microplastic neurotoxicity in rats

Advancing humanized 3D tumor modeling using an open access xeno-free medium

Toxic effects of Lepidium sativum seed fixed oil on Wistar albino rats in acute and subacute toxicity models

Modeling marine microplastic emissions in Life Cycle Assessment: characterization factors for biodegradable polymers and their application in a textile case study

Editorial: Global excellence in toxicology: Asia, Australia and New Zealand

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS