Frontiers in Toxicology | Developmental and Reproductive Toxicology

Systematic Review

Published on 24 Nov 2025

Endocrine disruption rewards: bisphenol-A-induced reproductive toxicity and the precision ameliorative potential of flavonoids in preclinical studies. A systematic review and meta-analysis

in Developmental and Reproductive Toxicology

Michael Ben Okon
Ilemobayo Victor Fasongbon
Dominic Swase
Reuben Samson Dangana
Wusa Makena
Vivian Onyinye Ojiakor
Ekom Monday Etukudo
Joan Chebet
Angela Mumbua Musyoka
Sandra Etumah Ifie

Frontiers in Toxicology

doi 10.3389/ftox.2025.1687862

504 views

Original Research

Published on 24 Nov 2025

Cadmium and glyphosate jointly compromise sperm function, fertilization, and early development in Prochilodus magdalenae

in Developmental and Reproductive Toxicology

Jose Espinosa-Araujo
Lucellys Sierra-Marquez
Victor Atencio-Garcia
Jesus Olivero-Verbel

Frontiers in Toxicology

doi 10.3389/ftox.2025.1698489

318 views

Systematic Review

Published on 19 Nov 2025

Systematic literature review and meta-analysis on the reproductive effects of micro- pollutants in humans and animals

in Developmental and Reproductive Toxicology

Luca Coppeta
Cristiana Ferrari
Lorenzo Ippoliti
Luisa Campagnolo
Andrea Magrini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1671098

672 views

Original Research

Accepted on 13 Nov 2025

Astragaloside IV Ameliorates Atrazine-Induced Male Reproductive Toxicity: An In vivo and In Silico Analysis

in Developmental and Reproductive Toxicology

Srinivasa Rao Sirasanagandla
Mohamed Al Mushaiqri
Firas Al-Majrafi
Nadia Al- Abri
Selvaraj Jayaraman
Isehaq Saif Al Huseini

Frontiers in Toxicology

210 views

Original Research

Accepted on 03 Nov 2025

Hazard identification and characterization of leachable chemicals from plastic products – a new PARC project

in Developmental and Reproductive Toxicology

Hubert Dirven
Aleksandra Bogusz
Hans Bouwmeester
Mathias Busch
Guillaume DUFLOS
Gunnar Eriksen
Margarida Fardilha
Daniela Flores-Gomez
Nina Franko
Laurent Gaté

Frontiers in Toxicology

228 views

Review

Published on 03 Oct 2025

Pesticides, an urgent challenge to global environmental health and planetary boundaries

in Developmental and Reproductive Toxicology

Laura N. Vandenberg
Elise J. Pierce
Rachel M. Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

2,296 views

Original Research

Published on 29 Sep 2025

In Vitro analysis of the effect of mono-(2-ethylhexyl) phthalate (MEHP) exposure on macrophage inflammatory responses in relationship to Leydig cell steroid production

in Developmental and Reproductive Toxicology

Akhil Adla
Allison Lunney
Barry Zirkin
Kassim Traore

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636395

1,174 views

Original Research

Published on 25 Sep 2025

Implementing a trilineage differentiation in the ReproTracker assay for improved teratogenicity assessment

in Developmental and Reproductive Toxicology

José M. Horcas-Nieto
Sabine Hartvelt
Luke Flatt
Jing Fang
Esther Lam
Gaonan Zhang
Romy Van Vliet
Marleen Feliksik
Tom Zwetsloot
Connor Philippo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645842

2,028 views

Hypothesis and Theory

Published on 21 Aug 2025

Determining a NOAEL for the consortium linking academic and regulatory insights on BPA toxicity (CLARITY-BPA) core study

in Developmental and Reproductive Toxicology

Melissa Badding
Noor Aly
Kevin Sondenheimer

Frontiers in Toxicology

doi 10.3389/ftox.2025.1639737

1,525 views

Original Research

Published on 30 Jun 2025

An advancement in developmental and reproductive toxicity (DART) risk assessment: evaluation of a bioactivity and exposure-based NAM toolbox

in Developmental and Reproductive Toxicology

Iris Mueller
Ashraf Abdelkhaliq
Paul Carmichael
Matthew Dent
Marleen Feliksik
Luke Flatt
Jade Houghton
José M. Horcas Nieto
Amer Jamalpoor
Predrag Kukic

Frontiers in Toxicology

doi 10.3389/ftox.2025.1602065

5,291 views
1 citation

Original Research

Published on 21 May 2025

Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina

in Developmental and Reproductive Toxicology

Florencia Doná
Virginia Lorenz
Georgina Stegmayer
Tamara Ricardo
Stefanía D’Iorio
Fernando Ponzo
María Rosa Repetti
Luisina Delma Demonte
María Mercedes Milesi
Jorgelina Varayoud

Frontiers in Toxicology

doi 10.3389/ftox.2025.1579952

3,191 views

Original Research

Published on 08 May 2025

Rat embryonic stem cell-based in vitro testing platform for mammalian embryo toxicology at pre- and post-implantation stages

in Developmental and Reproductive Toxicology

Corinne Quadalti
Marzia Moretti
Fabio Ferrazzi
Laura Calzà
Luciana Giardino
Vito Antonio Baldassarro

Frontiers in Toxicology

doi 10.3389/ftox.2025.1561386

2,337 views

Perspective

Published on 13 Mar 2025

Pesticides and public health: discussing risks in Brazilian agro-industrial growth

in Developmental and Reproductive Toxicology

Juliana E. Perobelli

Frontiers in Toxicology

doi 10.3389/ftox.2025.1442801

8,834 views
3 citations

Review

Published on 26 Feb 2025

Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology

in Developmental and Reproductive Toxicology

Isaac Karimi
Layth Jasim Mohammad
A. Suvitha
Zohreh Haidari
Helgi B. Schiöth

Frontiers in Toxicology

doi 10.3389/ftox.2025.1477822

3,005 views
2 citations

Systematic Review

Published on 17 Oct 2024

A systematic review and meta-analysis of the impact of triclosan exposure on human semen quality

in Developmental and Reproductive Toxicology

Cecilia Adedeji Adegbola
Tunmise Maryanne Akhigbe
Adetomiwa Ezekiel Adeogun
Eva Tvrdá
Alica Pizent
Roland Eghoghosoa Akhigbe

Frontiers in Toxicology

doi 10.3389/ftox.2024.1469340

2,892 views
5 citations

Perspective

Published on 11 Oct 2024

Reproductive toxicology: keeping up with our changing world

in Developmental and Reproductive Toxicology

Laura B. Miller
Morgan B. Feuz
Ralph G. Meyer
Mirella L. Meyer-Ficca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1456687

6,161 views