Review
Accepted on 12 Nov 2025
Mechanistic Read-Across Comes of Age: A Comparative Appraisal of EFSA 2025 Guidance, ECHA's RAAF, and Good Read-Across Practice
in Regulatory Toxicology
Frontiers in Toxicology
Type at least 3 characters
66 articles
Original Research
Published on 05 Nov 2025
Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1655330
- 1,524 views
Original Research
Published on 08 Oct 2025
Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1657708
- 1,414 views
Original Research
Published on 15 Sep 2025
Error-corrected next-generation sequencing mutagenicity assays in human HepaRG cells as human-relevant genetic toxicology new approach methodology
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1657189
- 1,446 views
Original Research
Published on 11 Aug 2025
Assessment of heated herbal products’ tobacco harm reduction potential: pre‐clinical and clinical studies
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1589480
- 3,371 views
Original Research
Published on 04 Aug 2025
Refinement of a workflow for human relevance assessment of adverse outcome pathways and associated new approach methodologies
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1616817
- 1,439 views
Perspective
Published on 17 Jul 2025
Stress convulsions in rodents: within a weight-of-evidence framework for human seizure risk
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1600816
- 1,285 views
Original Research
Published on 04 Jun 2025
Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1600127
- 5,823 views
Mini Review
Published on 14 May 2025
Optimizing Wnt activation in fetal calf serum (FCS)-free organoid expansion media
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1504469
- 2,170 views
- 1 citation
Original Research
Published on 14 Mar 2025
Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2025.1525089
- 2,145 views
Perspective
Published on 15 Jan 2025
Young TPI: empowering animal-free science among the next- generation of scientists
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2024.1521317
- 9,312 views
Editorial
Published on 10 Jan 2025
Editorial: Emerging topics on chemical safety assessment
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2024.1542469
- 2,141 views
- 1 citation
Editorial
Published on 18 Dec 2024
Editorial: Reducing animal use in carcinogenicity testing
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2024.1538905
- 1,210 views
Perspective
Published on 06 Dec 2024
Considering future qualification for regulatory science in the early development of microphysiological systems: a case study of microthrombosis in a Vessel-on-Chip
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2024.1513002
- 2,354 views
- 1 citation
Original Research
Published on 01 Nov 2024
Identifying non-essential uses to phase out substances of very high concern under REACH
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2024.1488336
- 3,924 views
Original Research
Published on 03 Oct 2024
Fulfilling the criteria for CLP classification: the implications for substances under the EU chemicals legislation
in Regulatory Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2024.1452065
- 3,565 views
- 1 citation