Frontiers in Toxicology

Original Research

Published on 01 Jul 2025

Tributyl phosphate as a type of environmental endocrine disruptor associated with liver fibrosis: insights from NHANES and in vitro validation

Liwei Yang
Aipeng Ju
Yawen Huang
Huibin Jiang
Jiaming Ye
Wen Qi
Liting Zhou

Frontiers in Toxicology

doi 10.3389/ftox.2025.1623830

194 views

Original Research

Published on 01 Jul 2025

Toxicity of glyphosate accelerates neurodegeneration in Caenorhabditis elegans model of Alzheimer’s disease

Nisha Rani
Mohammad Mumtaz Alam
Suhel Parvez

Frontiers in Toxicology

doi 10.3389/ftox.2025.1578230

345 views

Original Research

Published on 30 Jun 2025

An advancement in developmental and reproductive toxicity (DART) risk assessment: evaluation of a bioactivity and exposure-based NAM toolbox

Iris Mueller
Ashraf Abdelkhaliq
Paul Carmichael
Matthew Dent
Marleen Feliksik
Luke Flatt
Jade Houghton
José M. Horcas Nieto
Amer Jamalpoor
Predrag Kukic

Frontiers in Toxicology

doi 10.3389/ftox.2025.1602065

1,398 views

Review

Published on 30 Jun 2025

An adverse outcome pathway for cigarette smoke-mediated oxidative stress in plaque formation

Patrudu Makena
Linsey E. Haswell
Michael McEwan
Brian M. Keyser
David E. Smart
Robert Leverette
Kristen Jordan
Damien Breheny
Sarah Baxter-Wright

Frontiers in Toxicology

doi 10.3389/ftox.2025.1554747

584 views

Systematic Review

Published on 27 Jun 2025

Towards the standardization of human platelet lysate production and its comparison to fetal bovine serum for human hematopoietic cell culture: a scoping review

Shamili Immalaraju
Srishti Goyal
Rukmini Jonnalagadda

Frontiers in Toxicology

doi 10.3389/ftox.2025.1496231

376 views

Correction

Accepted on 26 Jun 2025

Correction: ASSOCIATIONS OF ENVIRONMENTAL POLLUTION WITH PRO-OXIDANT, ANTIOXIDANT AND INFLAMMATORY MARKERS IN PREGNANT MOTHERS AND NEWBORNS

Antonin Ambroz
Jiri Klema
Andrea Rossnerova
Alena Milcova
Anna Pastorkova
Jana Pulkrabova
Ondrej Parizek
Veronika Gomersall
Tomas Gramblicka
Jaroslav Zelenka

Frontiers in Toxicology

doi 10.3389/ftox.2025.1650125

105 views

Original Research

Accepted on 25 Jun 2025

Subchronic Effects of HgCl₂ on Cognitive Function and Central Inflammation in Type 2 Diabetic Rats: Involvement of BDNF and Acetylcholinesterase

Benloughmari Douae
Bikri Samir
ElAboubi Meriam
Yassif Fatima-Zahra
Youssef Aboussaleh

Frontiers in Toxicology

doi 10.3389/ftox.2025.1610720

Original Research

Accepted on 25 Jun 2025

Arsenic Toxicity in the Drosophila Brain at Single Cell Resolution

Anurag Chaturvedi
Vijay Shankar
Bibhu Simkhada
Rachel Lyman
Patrick Freymuth
Elisa Howansky
Katelynne Collins
Trudy Mackay
Robert Anholt

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636431

Original Research

Published on 25 Jun 2025

New psychoactive substances in roadway crash victims in California

Roy Gerona
Daniel Tomer
Donovan Nielsen
Allyson C. Sage
Deborah French
Juliana Tolles
James Alan Chenoweth

Frontiers in Toxicology

doi 10.3389/ftox.2025.1572324

713 views

Case Report

Published on 25 Jun 2025

Case Report: Evaluating toxic encephalopathy from occupational 1,2-dichloroethane exposure: magnetic resonance imaging contributions

Jieru Wang
Tianzi Jian
Guangcai Yu
Baotian Kan
Wei Li
Xiangdong Jian

Frontiers in Toxicology

doi 10.3389/ftox.2025.1557995

324 views

Review

Accepted on 23 Jun 2025

25 years of research and regulation: Is nanotechnology safe to commercialize?

Kirsten Rasmussen
Phil Sayre
Andrej Kobe
Mar Gonzalez
Hubert Rauscher

Frontiers in Toxicology

doi 10.3389/ftox.2025.1629813

110 views

Original Research

Published on 23 Jun 2025

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

Peter S. Walmod
Philip Kusk
Nina Jøhnk
Ieva Ankorina-Stark
Anthony Essex

Frontiers in Toxicology

doi 10.3389/ftox.2025.1585430

613 views

Original Research

Accepted on 20 Jun 2025

Assessment of a Heated Herbal Product's Tobacco Harm Reduction Potential: Pre-Clinical and Clinical Studies

Álvaro Marinas-Lacasta
Ian M Fearon
Matthew Stevenson
Tasnim Abusalem
Fiona Chapman
Edgar Trelles-Sticken
Roman Wieczorek
Sarah Jean Pour
Ole Dethloff
Ourania Komini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1589480

163 views

Brief Research Report

Accepted on 18 Jun 2025

Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding

Luiz Ladeira
Anouk Verhoeven
Jonas van Ertvelde
Jian Jiang
Alessio Gamba
Julen Sanz Serrano
Tamara Vanhaecke
Harm Heusinkveld
Ramiro Jover
Mathieu Vinken

Frontiers in Toxicology

doi 10.3389/ftox.2025.1619651

264 views

Original Research

Accepted on 18 Jun 2025

Refinement of a Workflow for Human Relevance Assessment of Adverse Outcome Pathways and Associated New Approach Methodologies

Annick D. van den Brand
Julia J. Meerman
Christina H.J. Veltman
Mirjam Luijten

Frontiers in Toxicology

doi 10.3389/ftox.2025.1616817

165 views

Original Research

Accepted on 17 Jun 2025

Chain Length-Dependent Mitochondrial Toxicity of Perfluoroalkyl Carboxylic Acids: Insights from Mito Tox

Yoonseok Kam
Lisa Winer
Natalia Romero

Frontiers in Toxicology

doi 10.3389/ftox.2025.1582891

173 views

524 Publications

Volume 7 - 2025

Tributyl phosphate as a type of environmental endocrine disruptor associated with liver fibrosis: insights from NHANES and in vitro validation

Toxicity of glyphosate accelerates neurodegeneration in Caenorhabditis elegans model of Alzheimer’s disease

An advancement in developmental and reproductive toxicity (DART) risk assessment: evaluation of a bioactivity and exposure-based NAM toolbox

An adverse outcome pathway for cigarette smoke-mediated oxidative stress in plaque formation

Towards the standardization of human platelet lysate production and its comparison to fetal bovine serum for human hematopoietic cell culture: a scoping review

Correction: ASSOCIATIONS OF ENVIRONMENTAL POLLUTION WITH PRO-OXIDANT, ANTIOXIDANT AND INFLAMMATORY MARKERS IN PREGNANT MOTHERS AND NEWBORNS

Subchronic Effects of HgCl₂ on Cognitive Function and Central Inflammation in Type 2 Diabetic Rats: Involvement of BDNF and Acetylcholinesterase

Arsenic Toxicity in the Drosophila Brain at Single Cell Resolution

New psychoactive substances in roadway crash victims in California

Case Report: Evaluating toxic encephalopathy from occupational 1,2-dichloroethane exposure: magnetic resonance imaging contributions

25 years of research and regulation: Is nanotechnology safe to commercialize?

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

Assessment of a Heated Herbal Product's Tobacco Harm Reduction Potential: Pre-Clinical and Clinical Studies

Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding

Refinement of a Workflow for Human Relevance Assessment of Adverse Outcome Pathways and Associated New Approach Methodologies

Chain Length-Dependent Mitochondrial Toxicity of Perfluoroalkyl Carboxylic Acids: Insights from Mito Tox