Frontiers in Toxicology

Original Research

Accepted on 09 Sep 2025

Acetaldehyde and Methylglyoxal: Comparative Analysis of Toxic Electronic Cigarette Degradation Products in 3D and 2D Exposure Systems using Human Bronchial Epithelial Models

Man Wong
Teresa Martinez
Nathan Hendricks
Prue Talbot

Frontiers in Toxicology

doi 10.3389/ftox.2025.1624794

260 views

Review

Published on 09 Sep 2025

Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation

Seo-Hyuk Chang
Jieun Jang
Wonjun Yang
Nam-Kyung Lee
Seoyeon Choi
Hyo-Il Jung
Wantae Kim
Boksik Cha
Sung-Jin Yoon
Ji-Yoon Noh

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636246

806 views

Case Report

Published on 09 Sep 2025

Mercury exposure leading to functional vitamin B12 deficiency and subacute combined degeneration: a case report and literature review

Isidora Semnic
Valentino Rački
Olivia Perković
Vladimira Vuletić

Frontiers in Toxicology

doi 10.3389/ftox.2025.1580275

930 views

Original Research

Published on 08 Sep 2025

Occupational exposure and its mechanistic link to allergic asthma and lung function decline; a data-driven approach coupled to mining of adverse outcome pathway signatures

Rob Stierum
Manosij Ghosh
Marjolein Meijerink
Xavier Pinho
Joost Westerhout
Vivi Schlünssen
Anjoeka Pronk
Jolanda van Bilsen

Frontiers in Toxicology

doi 10.3389/ftox.2025.1589380

1,001 views

Original Research

Published on 03 Sep 2025

Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study

Xingyao Yang
Xin Wang
Shifu Bao
Zhengjiang Li
Shuxing Xing
Zhangzhen Du

Frontiers in Toxicology

doi 10.3389/ftox.2025.1617663

930 views

Original Research

Accepted on 02 Sep 2025

In Vitro Analysis of the Effect of Mono-(2-ethylhexyl) Phthalate (MEHP) Exposure on Macrophage Inflammatory Responses in Relationship to Leydig Cell Steroid Production

Akhil Adla
Allison Lunney
Barry Zirkin
Kassim Traore

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636395

308 views

Review

Published on 29 Aug 2025

The impact of perfumes and cosmetic products on human health: a narrative review

Sharifa Alblooshi

Frontiers in Toxicology

doi 10.3389/ftox.2025.1646075

1,688 views

Original Research

Accepted on 28 Aug 2025

Danger on the Plate: Human health risks derived from the consumption of Angular Angelshark (Squatina guggenheim) meat in Southeastern Brazil

Amanda Pontes Lopes
Rebeca Dias Coutinho
Tatiana Dillenburg Saint’Pierre
Rachel Ann Hauser-Davis

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645858

316 views

Original Research

Accepted on 27 Aug 2025

Proliferation and metabolic activity of the Atlantic sturgeon cell line AOXlar7y under short-term serum-reduced conditions, and the effect of stimulation with growth factors and cytokines

Valeria Di Leonardo
Julia Brenmoehl
Heike Wanka
Bianka Grunow

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636776

479 views

Systematic Review

Published on 25 Aug 2025

Stroke risk following bee and wasp stings: a systematic review of ischemic and hemorrhagic events

Jorge Vasconez-Gonzalez
Juan S. Izquierdo-Condoy
Karen Delgado-Moreira
María de Lourdes Noboa-Lasso
Esteban Gamez-Rivera
Camila Salazar-Santoliva
María Belén Lopez-Molina
Esteban Ortiz-Prado

Frontiers in Toxicology

doi 10.3389/ftox.2025.1632308

1,559 views

Hypothesis and Theory

Published on 21 Aug 2025

Determining a NOAEL for the consortium linking academic and regulatory insights on BPA toxicity (CLARITY-BPA) core study

Melissa Badding
Noor Aly
Kevin Sondenheimer

Frontiers in Toxicology

doi 10.3389/ftox.2025.1639737

1,016 views

Original Research

Published on 21 Aug 2025

Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds

Brigitta R. Szabo
Jeroen Stein
Anna Savchenko
Thomas Hutschalik
Filip Van Nieuwerburgh
Tim Meese
Georgios Kosmidis
Paul G. A. Volders
Elena Matsa

Frontiers in Toxicology

doi 10.3389/ftox.2025.1644119

1,243 views

Original Research

Published on 18 Aug 2025

Validation of a novel questionnaire for assessing occupational exposure to organophosphate pesticides in Chilean agricultural workers

Liliana Zúñiga-Venegas
Natalia Landeros
Floria Pancetti
Sandra Cortés
Boris Lucero
Ana M. Brito
Ian S. Acuña-Rodríguez
María Teresa Muñoz-Quezada

Frontiers in Toxicology

doi 10.3389/ftox.2025.1588408

1,191 views

Perspective

Published on 11 Aug 2025

Uncovering exposome-related diseases through the pathologic metallome: a novel approach for clinical populations

Riccardo Leinardi
François Huaux

Frontiers in Toxicology

doi 10.3389/ftox.2025.1625874

868 views

Original Research

Published on 11 Aug 2025

Assessment of heated herbal products’ tobacco harm reduction potential: pre‐clinical and clinical studies

Alvaro-Flavio Marinas-Lacasta
Ian M. Fearon
Matthew Stevenson
Tasnim Abusalem
Fiona Chapman
Edgar Trelles Sticken
Roman Wieczorek
Sarah Jean Pour
Ole Dethloff
Ourania Komini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1589480

2,467 views

Original Research

Accepted on 08 Aug 2025

Reproduction of the Human Relevant Potency Threshold (HRPT) for Estrogen Receptor Alpha Agonism in an Inference Performance Screen for ICCVAM's Regulatory Scientific Confidence Framework

Jessica Ryman Ph.D., D.A.B.T.
Richard Becker

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657708

667 views

560 Publications

Volume 7 - 2025

Acetaldehyde and Methylglyoxal: Comparative Analysis of Toxic Electronic Cigarette Degradation Products in 3D and 2D Exposure Systems using Human Bronchial Epithelial Models

Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation

Mercury exposure leading to functional vitamin B12 deficiency and subacute combined degeneration: a case report and literature review

Occupational exposure and its mechanistic link to allergic asthma and lung function decline; a data-driven approach coupled to mining of adverse outcome pathway signatures

Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study

In Vitro Analysis of the Effect of Mono-(2-ethylhexyl) Phthalate (MEHP) Exposure on Macrophage Inflammatory Responses in Relationship to Leydig Cell Steroid Production

The impact of perfumes and cosmetic products on human health: a narrative review

Danger on the Plate: Human health risks derived from the consumption of Angular Angelshark (Squatina guggenheim) meat in Southeastern Brazil

Proliferation and metabolic activity of the Atlantic sturgeon cell line AOXlar7y under short-term serum-reduced conditions, and the effect of stimulation with growth factors and cytokines

Stroke risk following bee and wasp stings: a systematic review of ischemic and hemorrhagic events

Determining a NOAEL for the consortium linking academic and regulatory insights on BPA toxicity (CLARITY-BPA) core study

Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds

Validation of a novel questionnaire for assessing occupational exposure to organophosphate pesticides in Chilean agricultural workers

Uncovering exposome-related diseases through the pathologic metallome: a novel approach for clinical populations

Assessment of heated herbal products’ tobacco harm reduction potential: pre‐clinical and clinical studies

Reproduction of the Human Relevant Potency Threshold (HRPT) for Estrogen Receptor Alpha Agonism in an Inference Performance Screen for ICCVAM's Regulatory Scientific Confidence Framework