Frontiers in Toxicology

Original Research

Published on 29 Oct 2021

Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints

Lynea Murphy
Matthew J. LeBaron
Kamin Johnson
Reza J. Rasoulpour
Xiujuan Wang
Jessica LaRocca

Frontiers in Toxicology

doi 10.3389/ftox.2021.766196

2,070 views
3 citations

Review

Published on 27 Oct 2021

On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies

Camilla Lindgren Schwartz
Sofie Christiansen
Ulla Hass
Louise Ramhøj
Marta Axelstad
Nathalie Michelle Löbl
Terje Svingen

Frontiers in Toxicology

doi 10.3389/ftox.2021.730752

9,411 views
20 citations

Methods

Published on 15 Oct 2021

Development of the SciRAP Approach for Evaluating the Reliability and Relevance of in vitro Toxicity Data

Nicolas Roth
Johanna Zilliacus
Anna Beronius

Frontiers in Toxicology

doi 10.3389/ftox.2021.746430

10,161 views
47 citations

Original Research

Published on 08 Oct 2021

Effects of Prenatal Exposure to Titanium Dioxide Nanoparticles on DNA Methylation and Gene Expression Profile in the Mouse Brain

Ken Tachibana
Shotaro Kawazoe
Atsuto Onoda
Masakazu Umezawa
Ken Takeda

Frontiers in Toxicology

doi 10.3389/ftox.2021.705910

5,831 views
14 citations

Original Research

Published on 06 Oct 2021

Development of Microfluidic, Serum-Free Bronchial Epithelial Cells-on-a-Chip to Facilitate a More Realistic In vitro Testing of Nanoplastics

Govind Gupta
Srikanth Vallabani
Romain Bordes
Kunal Bhattacharya
Bengt Fadeel

Frontiers in Toxicology

doi 10.3389/ftox.2021.735331

6,277 views
18 citations

Original Research

Published on 01 Oct 2021

Influence of Aging on Bioaccumulation and Toxicity of Copper Oxide Nanoparticles and Dissolved Copper in the Sediment-Dwelling Oligochaete Tubifex tubifex: A Long-Term Study Using a Stable Copper Isotope

Amalie Thit
Monica Hamann Sandgaard
Joachim Sturve
Catherine Mouneyrac
Anders Baun
Henriette Selck

Frontiers in Toxicology

doi 10.3389/ftox.2021.737158

2,696 views
9 citations

Systematic Review

Published on 29 Sep 2021

Current Insights into Potential Effects of Micro-Nanoplastics on Human Health by in-vitro Tests

Marta Llorca
Marinella Farré

Frontiers in Toxicology

doi 10.3389/ftox.2021.752140

14,902 views
65 citations

Original Research

Published on 29 Sep 2021

Seasonally Related Disruption of Metabolism by Environmental Contaminants in Male Goldfish (Carassius auratus)

Lisa N. Bottalico
Julia Korlyakova
Aalim M. Weljie
Hamid R Habibi

Frontiers in Toxicology

doi 10.3389/ftox.2021.750870

3,004 views
6 citations

Review

Published on 13 Sep 2021

Potential of NRF2 Pathway in Preventing Developmental and Reproductive Toxicity of Fine Particles

Ying-Ji Li
Ken Takeda
Masayuki Yamamoto
Tomoyuki Kawada

Frontiers in Toxicology

doi 10.3389/ftox.2021.710225

3,482 views
3 citations

Brief Research Report

Published on 27 Aug 2021

Reports of Doses Administered and Adverse Reactions to Snake Antivenom Used in Uruguay in 2018

Alba Negrin
María Alejandra Battocletti
Carolina Juanena
Victor Morais

Frontiers in Toxicology

doi 10.3389/ftox.2021.690964

4,228 views
4 citations

Original Research

Published on 11 Aug 2021

Effect of Carbon Black Nanoparticle on Neonatal Lymphoid Tissues Depending on the Gestational Period of Exposure in Mice

Atsuto Onoda
Saki Okamoto
Ryuhei Shimizu
Yasser S. El-Sayed
Shiho Watanabe
Shuhei Ogawa
Ryo Abe
Masao Kamimura
Kohei Soga
Ken Tachibana

Frontiers in Toxicology

doi 10.3389/ftox.2021.700392

3,225 views
2 citations

Brief Research Report

Published on 19 Jul 2021

Analysis of Fluoride Contamination in Sheep Serum and in Water in the North East of Tunisia Ore Deposits

Rim Hadiji
Iheb Bannouri
Saida Zelfani
Aymen Mamlouk
Hela Jaballah
Arij Jemmal
Nadia Sdouga
Samir Ben Youssef

Frontiers in Toxicology

doi 10.3389/ftox.2021.643664

3,225 views
2 citations

Mini Review

Published on 19 Jul 2021

Insect in vitro System for Toxicology Studies — Current and Future Perspectives

Sheeja Cc
Damodaran Arun
Lekha Divya

Frontiers in Toxicology

doi 10.3389/ftox.2021.671600

4,791 views
5 citations

Brief Research Report

Published on 06 Jul 2021

The Aryl Hydrocarbon Receptor Suppresses Chronic Smoke-Induced Pulmonary Inflammation

Necola Guerrina
Hussein Traboulsi
David H. Eidelman
Carolyn J. Baglole

Frontiers in Toxicology

doi 10.3389/ftox.2021.653569

3,196 views
11 citations

Brief Research Report

Published on 05 Jul 2021

Impact of Quantisal® Oral Fluid Collection Device on Drug Stability

Michela Riggio
Keyur A. Dave
Branko Koscak
Mark Blakey
Charles Appleton

Frontiers in Toxicology

doi 10.3389/ftox.2021.670656

11,343 views
1 citation

Review

Published on 05 Jul 2021

Developmental Exposure to Endocrine Disrupting Chemicals and Its Impact on Cardio-Metabolic-Renal Health

Radha Dutt Singh
Kavita Koshta
Ratnakar Tiwari
Hafizurrahman Khan
Vineeta Sharma
Vikas Srivastava

Frontiers in Toxicology

doi 10.3389/ftox.2021.663372

9,722 views
21 citations

Review

Published on 29 Jun 2021

Spatiotemporal Small Non-coding RNAs Expressed in the Germline as an Early Biomarker of Testicular Toxicity and Transgenerational Effects Caused by Prenatal Exposure to Nanosized Particles

Satoshi Yokota
Ken Takeda
Shigeru Oshio

Frontiers in Toxicology

doi 10.3389/ftox.2021.691070

3,990 views
9 citations

Original Research

Published on 24 Jun 2021

Threshold of Toxicological Concern—An Update for Non-Genotoxic Carcinogens

Monika Batke
Fatemeh Moradi Afrapoli
Rupert Kellner
James F. Rathman
Chihae Yang
Mark T. D. Cronin
Sylvia E. Escher

Frontiers in Toxicology

doi 10.3389/ftox.2021.688321

12,346 views
12 citations

Original Research

Published on 22 Jun 2021

Untargeted Proteomics-Based Approach to Investigate Unintended Changes in Genetically Modified Maize for Environmental Risk Assessment Purpose

Sarah Zanon Agapito-Tenfen
Miguel Pedro Guerra
Rubens Onofre Nodari
Odd-Gunnar Wikmark

Frontiers in Toxicology

doi 10.3389/ftox.2021.655968

5,061 views
6 citations

Original Research

Published on 15 Jun 2021

Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification

Preethi Thunga
Lisa Truong
Robyn L. Tanguay
David M. Reif

Frontiers in Toxicology

doi 10.3389/ftox.2021.670496

3,646 views
8 citations

Mini Review

Published on 03 Jun 2021

Prospect of in vitro Bile Fluids Collection in Improving Cell-Based Assay of Liver Function

Astia Rizki-Safitri
Fumiya Tokito
Masaki Nishikawa
Minoru Tanaka
Kazuya Maeda
Hiroyuki Kusuhara
Yasuyuki Sakai

Frontiers in Toxicology

doi 10.3389/ftox.2021.657432

6,719 views
2 citations

Original Research

Published on 28 May 2021

Prediction of Skin Sensitization Potential of Silver and Zinc Oxide Nanoparticles Through the Human Cell Line Activation Test

Ravi Gautam
SuJeong Yang
Anju Maharjan
JiHun Jo
Manju Acharya
Yong Heo
ChangYul Kim

Frontiers in Toxicology

doi 10.3389/ftox.2021.649666

8,669 views
22 citations

Original Research

Published on 26 May 2021

Association of Prenatal Ambient Air Pollution Exposure With Placental Mitochondrial DNA Copy Number, Telomere Length and Preeclampsia

Yumjirmaa Mandakh
Anna Oudin
Lena Erlandsson
Christina Isaxon
Stefan R. Hansson
Karin Broberg
Ebba Malmqvist

Frontiers in Toxicology

doi 10.3389/ftox.2021.659407

6,074 views
14 citations

Original Research

Published on 14 May 2021

Adult Male Rats Show Resilience to Adolescent Bisphenol A Effects on Hormonal and Behavioral Responses While Co-Exposure With Hop Extracts Supports Synergistic Actions

Alexandre Morin
Lise Van de Beeck
Emmanuelle Person
Helene Plamondon

Frontiers in Toxicology

doi 10.3389/ftox.2021.639820

5,138 views
6 citations

69 Publications

volumes

Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints

On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies

Development of the SciRAP Approach for Evaluating the Reliability and Relevance of in vitro Toxicity Data

Effects of Prenatal Exposure to Titanium Dioxide Nanoparticles on DNA Methylation and Gene Expression Profile in the Mouse Brain

Development of Microfluidic, Serum-Free Bronchial Epithelial Cells-on-a-Chip to Facilitate a More Realistic In vitro Testing of Nanoplastics

Influence of Aging on Bioaccumulation and Toxicity of Copper Oxide Nanoparticles and Dissolved Copper in the Sediment-Dwelling Oligochaete Tubifex tubifex: A Long-Term Study Using a Stable Copper Isotope

Current Insights into Potential Effects of Micro-Nanoplastics on Human Health by in-vitro Tests

Seasonally Related Disruption of Metabolism by Environmental Contaminants in Male Goldfish (Carassius auratus)

Potential of NRF2 Pathway in Preventing Developmental and Reproductive Toxicity of Fine Particles

Reports of Doses Administered and Adverse Reactions to Snake Antivenom Used in Uruguay in 2018

Effect of Carbon Black Nanoparticle on Neonatal Lymphoid Tissues Depending on the Gestational Period of Exposure in Mice

Analysis of Fluoride Contamination in Sheep Serum and in Water in the North East of Tunisia Ore Deposits

Insect in vitro System for Toxicology Studies — Current and Future Perspectives

The Aryl Hydrocarbon Receptor Suppresses Chronic Smoke-Induced Pulmonary Inflammation

Impact of Quantisal® Oral Fluid Collection Device on Drug Stability

Developmental Exposure to Endocrine Disrupting Chemicals and Its Impact on Cardio-Metabolic-Renal Health

Spatiotemporal Small Non-coding RNAs Expressed in the Germline as an Early Biomarker of Testicular Toxicity and Transgenerational Effects Caused by Prenatal Exposure to Nanosized Particles

Threshold of Toxicological Concern—An Update for Non-Genotoxic Carcinogens

Untargeted Proteomics-Based Approach to Investigate Unintended Changes in Genetically Modified Maize for Environmental Risk Assessment Purpose

Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification

Prospect of in vitro Bile Fluids Collection in Improving Cell-Based Assay of Liver Function

Prediction of Skin Sensitization Potential of Silver and Zinc Oxide Nanoparticles Through the Human Cell Line Activation Test

Association of Prenatal Ambient Air Pollution Exposure With Placental Mitochondrial DNA Copy Number, Telomere Length and Preeclampsia

Adult Male Rats Show Resilience to Adolescent Bisphenol A Effects on Hormonal and Behavioral Responses While Co-Exposure With Hop Extracts Supports Synergistic Actions