Frontiers in Toxicology

Original Research

Published on 27 Sep 2022

Exposure to environmental contaminants and folic acid supplementation intergenerationally impact fetal skeleton development through the paternal lineage in a rat model

Phanie L. Charest
Emmanuel Tessougue
Maryse Lessard
Pauline M. Herst
Pauline Navarro
Sarah Kimmins
Jacquetta M. Trasler
Amanda J. MacFarlane
Marie-Odile Benoit-Biancamano
Janice L. Bailey

Frontiers in Toxicology

doi 10.3389/ftox.2022.881622

4,039 views
2 citations

Original Research

Published on 26 Sep 2022

First report on atrazine monitoring in drinking water from Ijebu-North, South-West Nigeria: Human health risk evaluation and reproductive toxicity studies

Folarin Owagboriaye
Rasheed Oladunjoye
Oladunni Adekunle
Mistura Adeleke
Titilola Salisu
Adedamola Adenekan
Abibat Sulaimon
Gabriel Dedeke
Olusegun Lawal

Frontiers in Toxicology

doi 10.3389/ftox.2022.975636

4,443 views
9 citations

Original Research

Published on 23 Sep 2022

Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip® assay in TK6 cells

Julie K. Buick
Andrea Rowan-Carroll
Rémi Gagné
Andrew Williams
Renxiang Chen
Heng-Hong Li
Albert J. Fornace
Christy Chao
Bevin P. Engelward
Roland Frötschl

Frontiers in Toxicology

doi 10.3389/ftox.2022.991590

4,599 views
7 citations

Original Research

Published on 23 Sep 2022

In vitro biotransformation assays using fish liver cells: Comparing rainbow trout and carp hepatocytes

Ina Bischof
Jon A. Arnot
Heinrich Jürling
Georg Knipschild
Christian Schlechtriem
Anna Schauerte
Helmut Segner

Frontiers in Toxicology

doi 10.3389/ftox.2022.1021880

3,165 views
4 citations

Mini Review

Published on 20 Sep 2022

The intertwining between lead and ethanol in the model organism Caenorhabditis elegans

P. A. Albrecht
L .E. Fernandez-Hubeid
R. Deza-Ponzio
M. B. Virgolini

Frontiers in Toxicology

doi 10.3389/ftox.2022.991787

3,405 views
5 citations

Original Research

Published on 20 Sep 2022

Using in vitro bioassays to guide the development of safer bio-based polymers for use in food packaging

Emma Harper
Eoin Cunningham
Lisa Connolly

Frontiers in Toxicology

doi 10.3389/ftox.2022.936014

20,019 views
5 citations

Editorial

Published on 20 Sep 2022

Editorial: Occupational exposure to nanomaterials

Charlene Andraos
Mary Gulumian
Gaku Ichihara
Boowook Kim
Il Je Yu

Frontiers in Toxicology

doi 10.3389/ftox.2022.1014600

1,913 views
5 citations

Original Research

Published on 20 Sep 2022

Novel machine learning models to predict endocrine disruption activity for high-throughput chemical screening

Sean P. Collins
Tara S. Barton-Maclaren

Frontiers in Toxicology

doi 10.3389/ftox.2022.981928

4,647 views
13 citations

Original Research

Published on 19 Sep 2022

Prioritization of chemicals in food for risk assessment by integrating exposure estimates and new approach methodologies: A next generation risk assessment case study

Mirjam Luijten
R. Corinne Sprong
Emiel Rorije
Leo T. M. van der Ven

Frontiers in Toxicology

doi 10.3389/ftox.2022.933197

6,606 views
7 citations

Review

Published on 16 Sep 2022

Quaternary ammonium compounds in hypersensitivity reactions

Marine Peyneau
Luc de Chaisemartin
Nicolas Gigant
Sylvie Chollet-Martin
Saadia Kerdine-Römer

Frontiers in Toxicology

doi 10.3389/ftox.2022.973680

26,623 views
37 citations

Original Research

Published on 16 Sep 2022

Fate of engineered nanomaterials at the human epithelial lung tissue barrier in vitro after single and repeated exposures

Roman Lehner
Ilaria Zanoni
Anne Banuscher
Anna Luisa Costa
Barbara Rothen-Rutishauser

Frontiers in Toxicology

doi 10.3389/ftox.2022.918633

2,341 views
5 citations

Perspective

Published on 09 Sep 2022

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of tobacco and other nicotine-containing products

Jacqueline Miller-Holt
Holger P. Behrsing
Amy J. Clippinger
Carole Hirn
Todd J. Stedeford
Andreas O. Stucki

Frontiers in Toxicology

doi 10.3389/ftox.2022.943358

6,356 views
13 citations

Methods

Published on 07 Sep 2022

The colony forming efficiency assay for toxicity testing of nanomaterials—Modifications for higher-throughput

Elise Rundén-Pran
Espen Mariussen
Naouale El Yamani
Elisabeth Elje
Eleonora Marta Longhin
Maria Dusinska

Frontiers in Toxicology

doi 10.3389/ftox.2022.983316

13,406 views
22 citations

Original Research

Published on 05 Sep 2022

Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials

Sebastin Martin
Laura de Haan
Ignacio Miro Estruch
Kai Moritz Eder
Anne Marzi
Jürgen Schnekenburger
Magda Blosi
Anna Costa
Giulia Antonello
Enrico Bergamaschi

Frontiers in Toxicology

doi 10.3389/ftox.2022.974429

4,338 views
6 citations

Review

Published on 01 Sep 2022

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health

Andreas O. Stucki
Tara S. Barton-Maclaren
Yadvinder Bhuller
Joseph E. Henriquez
Tala R. Henry
Carole Hirn
Jacqueline Miller-Holt
Edith G. Nagy
Monique M. Perron
Deborah E. Ratzlaff

Frontiers in Toxicology

doi 10.3389/ftox.2022.964553

55,642 views
208 citations

Review

Published on 31 Aug 2022

Developmental and reproductive toxic effects of exposure to microplastics: A review of associated signaling pathways

Itishree Dubey
Sabbir Khan
Sapana Kushwaha

Frontiers in Toxicology

doi 10.3389/ftox.2022.901798

18,528 views
75 citations

Original Research

Published on 29 Aug 2022

Effects of gestational low dose perfluorooctanoic acid on maternal and “anxiety-like” behavior in dams

Alyssa K. Merrill
Katherine Conrad
Elena Marvin
Marissa Sobolewski

Frontiers in Toxicology

doi 10.3389/ftox.2022.971970

5,040 views
16 citations

Original Research

Published on 25 Aug 2022

Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene

Lindsay B. Wilson
Ryan S. McClure
Katrina M. Waters
Michael T. Simonich
Robyn L. Tanguay

Frontiers in Toxicology

doi 10.3389/ftox.2022.950503

4,100 views
17 citations

Brief Research Report

Published on 24 Aug 2022

Fluorescently labeled nuclear morphology is highly informative of neurotoxicity

Shijie Wang
Jeremy W. Linsley
Drew A. Linsley
Josh Lamstein
Steven Finkbeiner

Frontiers in Toxicology

doi 10.3389/ftox.2022.935438

3,609 views
4 citations

Original Research

Published on 22 Aug 2022

Chronic atrazine exposure increases the expression of genes associated with GABAergic and glutamatergic systems in the brain of male albino rat

D. Y. Reyes-Bravo
P. Villalobos-Aguilera
J. T. Almonte-Zepeda
M. S. Mendoza-Trejo
M. Giordano
A. Orozco
V. M. Rodríguez

Frontiers in Toxicology

doi 10.3389/ftox.2022.933300

2,717 views
5 citations

Original Research

Published on 22 Aug 2022

Dynamic Mass Balance Modeling for Chemical Distribution Over Time in In Vitro Systems With Repeated Dosing

Sherri Bloch
Jon A. Arnot
Nynke I. Kramer
James M. Armitage
Marc-André Verner

Frontiers in Toxicology

doi 10.3389/ftox.2022.911128

3,685 views
4 citations

Review

Published on 19 Aug 2022

Aquatic organisms modulate the bioreactivity of engineered nanoparticles: focus on biomolecular corona

Wei Liu
Isabelle A. M. Worms
Željko Jakšić
Vera I. Slaveykova

Frontiers in Toxicology

doi 10.3389/ftox.2022.933186

3,369 views
12 citations

Mini Review

Published on 19 Aug 2022

Multigenerational metabolic disruption: Developmental origins and mechanisms of propagation across generations

Daniel D. Davis
Carlos Diaz-Castillo
Raquel Chamorro-Garcia

Frontiers in Toxicology

doi 10.3389/ftox.2022.902201

3,258 views
5 citations

Mini Review

Published on 11 Aug 2022

Standardisation and international adoption of defined approaches for skin sensitisation

Silvia Casati
David Asturiol
Patience Browne
Nicole Kleinstreuer
Michèle Régimbald-Krnel
Pierre Therriault

Frontiers in Toxicology

doi 10.3389/ftox.2022.943152

3,049 views
10 citations

136 Publications

volumes

Exposure to environmental contaminants and folic acid supplementation intergenerationally impact fetal skeleton development through the paternal lineage in a rat model

First report on atrazine monitoring in drinking water from Ijebu-North, South-West Nigeria: Human health risk evaluation and reproductive toxicity studies

Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip® assay in TK6 cells

In vitro biotransformation assays using fish liver cells: Comparing rainbow trout and carp hepatocytes

The intertwining between lead and ethanol in the model organism Caenorhabditis elegans

Using in vitro bioassays to guide the development of safer bio-based polymers for use in food packaging

Editorial: Occupational exposure to nanomaterials

Novel machine learning models to predict endocrine disruption activity for high-throughput chemical screening

Prioritization of chemicals in food for risk assessment by integrating exposure estimates and new approach methodologies: A next generation risk assessment case study

Quaternary ammonium compounds in hypersensitivity reactions

Fate of engineered nanomaterials at the human epithelial lung tissue barrier in vitro after single and repeated exposures

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of tobacco and other nicotine-containing products

The colony forming efficiency assay for toxicity testing of nanomaterials—Modifications for higher-throughput

Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health

Developmental and reproductive toxic effects of exposure to microplastics: A review of associated signaling pathways

Effects of gestational low dose perfluorooctanoic acid on maternal and “anxiety-like” behavior in dams

Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene

Fluorescently labeled nuclear morphology is highly informative of neurotoxicity

Chronic atrazine exposure increases the expression of genes associated with GABAergic and glutamatergic systems in the brain of male albino rat

Dynamic Mass Balance Modeling for Chemical Distribution Over Time in In Vitro Systems With Repeated Dosing

Aquatic organisms modulate the bioreactivity of engineered nanoparticles: focus on biomolecular corona

Multigenerational metabolic disruption: Developmental origins and mechanisms of propagation across generations

Standardisation and international adoption of defined approaches for skin sensitisation