Frontiers in Toxicology

Original Research

Published on 22 Jul 2025

A deep-learning approach to predict reproductive toxicity of chemicals using communicative message passing neural network

Owen He
Daoxing Chen
Yimei Li

Frontiers in Toxicology

doi 10.3389/ftox.2025.1640612

2,849 views

Perspective

Published on 17 Jul 2025

Stress convulsions in rodents: within a weight-of-evidence framework for human seizure risk

Joseph J. DeGeorge
Monica R. Metea

Frontiers in Toxicology

doi 10.3389/ftox.2025.1600816

1,566 views

Original Research

Published on 15 Jul 2025

Chain length-dependent mitochondrial toxicity of perfluoroalkyl carboxylic acids: insights from Mito Tox Index evaluation

Yoonseok Kam
Lisa Winer
Natalia Romero

Frontiers in Toxicology

doi 10.3389/ftox.2025.1582891

2,508 views
2 citations

Original Research

Published on 14 Jul 2025

Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

Douae Benloughmari
Samir Bikri
Meriam El Aboubi
Fatima-Zahra Yassif
Youssef Aboussaleh

Frontiers in Toxicology

doi 10.3389/ftox.2025.1610720

1,757 views

Original Research

Published on 10 Jul 2025

Arsenic toxicity in the Drosophila brain at single cell resolution

Anurag Chaturvedi
Vijay Shankar
Bibhu Simkhada
Rachel A. Lyman
Patrick Freymuth
Elisabeth Howansky
Katelynne M. Collins
Trudy F. C. Mackay
Robert R. H. Anholt

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636431

2,638 views

Review

Published on 10 Jul 2025

25 years of research and regulation: Is nanotechnology safe to commercialize?

Kirsten Rasmussen
Phil Sayre
Andrej Kobe
Mar Gonzalez
Hubert Rauscher

Frontiers in Toxicology

doi 10.3389/ftox.2025.1629813

5,213 views
1 citation

Brief Research Report

Published on 07 Jul 2025

Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding

Luiz Ladeira
Anouk Verhoeven
Jonas van Ertvelde
Jian Jiang
Alessio Gamba
Julen Sanz-Serrano
Tamara Vanhaecke
Harm J. Heusinkveld
Ramiro Jover
Mathieu Vinken

Frontiers in Toxicology

doi 10.3389/ftox.2025.1619651

3,555 views
1 citation

Correction

Published on 04 Jul 2025

Correction: Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns

Antonin Ambroz
Jiri Klema
Andrea Rossnerova
Alena Milcova
Anna Pastorkova
Jana Pulkrabova
Ondrej Parizek
Veronika Gomersall
Tomas Gramblicka
Jaroslav Zelenka

Frontiers in Toxicology

doi 10.3389/ftox.2025.1650125

996 views
1 citation

Original Research

Published on 01 Jul 2025

Toxicity of glyphosate accelerates neurodegeneration in Caenorhabditis elegans model of Alzheimer’s disease

Nisha Rani
Mohammad Mumtaz Alam
Suhel Parvez

Frontiers in Toxicology

doi 10.3389/ftox.2025.1578230

2,496 views
2 citations

Original Research

Published on 01 Jul 2025

Tributyl phosphate as a type of environmental endocrine disruptor associated with liver fibrosis: insights from NHANES and in vitro validation

Liwei Yang
Aipeng Ju
Yawen Huang
Huibin Jiang
Jiaming Ye
Wen Qi
Liting Zhou

Frontiers in Toxicology

doi 10.3389/ftox.2025.1623830

2,364 views

Original Research

Published on 30 Jun 2025

An advancement in developmental and reproductive toxicity (DART) risk assessment: evaluation of a bioactivity and exposure-based NAM toolbox

Iris Mueller
Ashraf Abdelkhaliq
Paul Carmichael
Matthew Dent
Marleen Feliksik
Luke Flatt
Jade Houghton
José M. Horcas Nieto
Amer Jamalpoor
Predrag Kukic

Frontiers in Toxicology

doi 10.3389/ftox.2025.1602065

5,725 views
1 citation

Review

Published on 30 Jun 2025

An adverse outcome pathway for cigarette smoke-mediated oxidative stress in plaque formation

Patrudu Makena
Linsey E. Haswell
Michael McEwan
Brian M. Keyser
David E. Smart
Robert Leverette
Kristen Jordan
Damien Breheny
Sarah Baxter-Wright

Frontiers in Toxicology

doi 10.3389/ftox.2025.1554747

2,492 views
2 citations

Systematic Review

Published on 27 Jun 2025

Towards the standardization of human platelet lysate production and its comparison to fetal bovine serum for human hematopoietic cell culture: a scoping review

Shamili Immalaraju
Srishti Goyal
Rukmini Jonnalagadda

Frontiers in Toxicology

doi 10.3389/ftox.2025.1496231

3,374 views
2 citations

Original Research

Published on 25 Jun 2025

New psychoactive substances in roadway crash victims in California

Roy Gerona
Daniel Tomer
Donovan Nielsen
Allyson C. Sage
Deborah French
Juliana Tolles
James Alan Chenoweth

Frontiers in Toxicology

doi 10.3389/ftox.2025.1572324

3,311 views
2 citations

Case Report

Published on 25 Jun 2025

Case Report: Evaluating toxic encephalopathy from occupational 1,2-dichloroethane exposure: magnetic resonance imaging contributions

Jieru Wang
Tianzi Jian
Guangcai Yu
Baotian Kan
Wei Li
Xiangdong Jian

Frontiers in Toxicology

doi 10.3389/ftox.2025.1557995

1,948 views
1 citation

Original Research

Published on 23 Jun 2025

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

Peter S. Walmod
Philip Kusk
Nina Jøhnk
Ieva Ankorina-Stark
Anthony Essex

Frontiers in Toxicology

doi 10.3389/ftox.2025.1585430

2,592 views

Original Research

Published on 12 Jun 2025

Bioengineering of novel organotypic 3D human liver tissue model for drug-induced liver injury and toxicity studies

Camden Holm
Joseph Finelli
Mateo Frare
Alex Armento
Seyoum Ayehunie

Frontiers in Toxicology

doi 10.3389/ftox.2025.1574387

3,096 views

Review

Published on 09 Jun 2025

Cannabis concentrate vaping chemistry

Kaelas R. Munger
Killian M. Anreise
Robert M. Strongin

Frontiers in Toxicology

doi 10.3389/ftox.2025.1568207

5,649 views
1 citation

Original Research

Published on 06 Jun 2025

The patterns of dynamic changes in blood toxicant levels, prognosis, and regression in a case of occupational chlorfenapyr exposure

Jianjian Liu
Zhaozhao Shan
Chen Wang
Xiangdong Jian
Baotian Kan
Yingli Ren

Frontiers in Toxicology

doi 10.3389/ftox.2025.1570887

2,063 views

Original Research

Published on 04 Jun 2025

Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values

Taylor Builee
Todd A. Kennedy
Valériane Levelut
Megan A. Hahn
Stephen Bond
Michael K. Peterson
Frances K. Hsia
Alessia Stornetta
Kristin J. Erickson
Kimberly D. Ehman

Frontiers in Toxicology

doi 10.3389/ftox.2025.1600127

6,358 views

Systematic Review

Published on 30 May 2025

A systematic review of the effects of nanoplastics on fish

Asok K. Dasmahapatra
Joydeep Chatterjee
Paul B. Tchounwou

Frontiers in Toxicology

doi 10.3389/ftox.2025.1530209

5,746 views
5 citations

Original Research

Published on 27 May 2025

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs

Thao Vo
Sonika Patial
Yogesh Saini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1540468

1,967 views

Original Research

Published on 26 May 2025

Immunotoxicity assessment of multiwalled carbon nanotubes following whole-body inhalation exposure for 30 and 90 days in B6C3F1/N mice and 30 days in HSD:Harlan Sprague Dawley SD® rats

Victor J. Johnson
Nigel J. Walker
Michael I. Luster
Gary R. Burleson
Michelle Cora
Gregory L. Baker
Barney Sparrow
Dori R. Germolec

Frontiers in Toxicology

doi 10.3389/ftox.2025.1539810

1,898 views
1 citation

Original Research

Published on 21 May 2025

Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina

Florencia Doná
Virginia Lorenz
Georgina Stegmayer
Tamara Ricardo
Stefanía D’Iorio
Fernando Ponzo
María Rosa Repetti
Luisina Delma Demonte
María Mercedes Milesi
Jorgelina Varayoud

Frontiers in Toxicology

doi 10.3389/ftox.2025.1579952

3,405 views
1 citation

160 Publications

volumes

A deep-learning approach to predict reproductive toxicity of chemicals using communicative message passing neural network

Stress convulsions in rodents: within a weight-of-evidence framework for human seizure risk

Chain length-dependent mitochondrial toxicity of perfluoroalkyl carboxylic acids: insights from Mito Tox Index evaluation

Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

Arsenic toxicity in the Drosophila brain at single cell resolution

25 years of research and regulation: Is nanotechnology safe to commercialize?

Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding

Correction: Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns

Toxicity of glyphosate accelerates neurodegeneration in Caenorhabditis elegans model of Alzheimer’s disease

Tributyl phosphate as a type of environmental endocrine disruptor associated with liver fibrosis: insights from NHANES and in vitro validation

An advancement in developmental and reproductive toxicity (DART) risk assessment: evaluation of a bioactivity and exposure-based NAM toolbox

An adverse outcome pathway for cigarette smoke-mediated oxidative stress in plaque formation

Towards the standardization of human platelet lysate production and its comparison to fetal bovine serum for human hematopoietic cell culture: a scoping review

New psychoactive substances in roadway crash victims in California

Case Report: Evaluating toxic encephalopathy from occupational 1,2-dichloroethane exposure: magnetic resonance imaging contributions

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

Bioengineering of novel organotypic 3D human liver tissue model for drug-induced liver injury and toxicity studies

Cannabis concentrate vaping chemistry

The patterns of dynamic changes in blood toxicant levels, prognosis, and regression in a case of occupational chlorfenapyr exposure

Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values

A systematic review of the effects of nanoplastics on fish

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs

Immunotoxicity assessment of multiwalled carbon nanotubes following whole-body inhalation exposure for 30 and 90 days in B6C3F1/N mice and 30 days in HSD:Harlan Sprague Dawley SD® rats

Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina