Frontiers in Toxicology

Original Research

Published on 17 Feb 2026

Effect of the cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on in vivo platelet activation, oxidative stress, and procoagulant responses induced by waterpipe smoke exposure in mice

Sumaya Beegam
Nur. E. Zaaba
Ozaz Elzaki
Javed Yasin
Badreldin H. Ali
Abderrahim Nemmar

Frontiers in Toxicology

doi 10.3389/ftox.2026.1696863

186 views

Original Research

Accepted on 16 Feb 2026

Deciphering the toxicological mechanism of airway allergic diseases caused by Dioctyl terephthalate: a composite study

Zhi-qiang Zhang
You-wei Bao
Hongyou Wang
Jing-yang Li
Heng Wang
Xinyue Yang
Qi Chen
Jun Wu
Xinhua Zhu

Frontiers in Toxicology

Perspective

Accepted on 16 Feb 2026

From Prediction to Adaptation: Rethinking the Epistemic Role of Inhalation Toxicology

Samir Dekali

Frontiers in Toxicology

Original Research

Accepted on 16 Feb 2026

In Vitro BBB Triculture Assay and Preliminary Computational Model Development to Predict Brain Exposure

Zhuangyan (Monica) Xu
James Patrick Sluka
Charlie C Zhang
Gregory Thomas Knipp

Frontiers in Toxicology

Review

Accepted on 13 Feb 2026

Micro/Nanoplastics Pollution: Emerging Challenges for Aquatic Animals and Food Crops

Shrutarshee Kundu
Neeraj Kumar
Paritosh Kumar
Basavaraj PS
Ajay K Singh
Dipti Godse
Kotha Sammi Reddy

Frontiers in Toxicology

131 views

Review

Accepted on 12 Feb 2026

"Algal-dromes": A Novel Conceptual Approach to Illness in Humans Exposed to Harmful Algal Bloom Toxins

Brett Johnson
Mindy Richlen
Jeffrey Lai
Michael J. Twiner

Frontiers in Toxicology

Original Research

Accepted on 12 Feb 2026

Invisible Victims: Rising Pediatric Cocaine Exposures in France (2020–2024) – Insights from the National Poison Center Database

Katharina von Fabeck
Mathieu Glaizal
Corinne Schmitt
Romain Torrents
Nicolas Simon

Frontiers in Toxicology

Original Research

Published on 12 Feb 2026

Use of gastroscopy in the management of pediatric toxic ingestions: insights from a decade of experience – a retrospective study

Marco Marano
Lavinia Di Meglio
Mara Pisani
Bianca Maria Goffredo
Carla Olita
Simona Faraci
Francesca Rea
Salvatore Perdichizzi
Giorgio Zampini
Piero David

Frontiers in Toxicology

doi 10.3389/ftox.2026.1678559

454 views

Original Research

Accepted on 11 Feb 2026

Effects of predicted Khamisiyah exposure on default mode network resting state functional connectivity in Gulf War Veterans

Linda L. Chao
Salvatore Torrisi

Frontiers in Toxicology

141 views

Original Research

Published on 10 Feb 2026

Microplastics amplify the pro-inflammatory response to fungal mycelial fragments and spores in neutrophil-like cells

Anani K. Afanou
Andreas Solberg Sagen
Francesco Barbero
Ilaria Zanoni
Anna Costa
Øyvind P. Haugen
Shan Zienolddiny-Narui

Frontiers in Toxicology

doi 10.3389/ftox.2026.1718466

682 views

Original Research

Accepted on 09 Feb 2026

Ecotoxicological Thresholds of Glyphosate: Linking Sub-Lethal Exposure to Liver Tissue Damage and Behavioural Disturbances in African Catfish

Bethel Uchenna Udume
Anyaele Uka
Glory Nnenna Oji
Chieze Precious Chikezie
Chidi Onyewuchi
Obiahu Henry Ota

Frontiers in Toxicology

194 views

Original Research

Accepted on 09 Feb 2026

Protective Effects of Lagerstroemia speciosa Against Paracetamol-Induced Renal and Testicular Toxicity in Rats via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Mechanisms

Nagham E. Elsheshtawy
Engy Risha
Fatma M. Abdelhamid
Bodour Rajab
Rehab Bagadood
Bayan Bokhari
Ghadir Sindi
Ahmed I. Ateya
Shimaa Rezk
Mohamed El-Boshy

Frontiers in Toxicology

171 views

Mini Review

Published on 09 Feb 2026

From prioritization to implementation: updating the PARC WP5 project portfolio through the second prioritization round

Celia Garcia Arenas
Kiara Aiello Holden
Terje Svingen
Dries Knapen
Saadia Kerdine-Römer
Birgitte Lindeman
Nicola M. Smith
Ludovic Le Hegarat
Tamara Vanhaecke
Gilles Rivière

Frontiers in Toxicology

doi 10.3389/ftox.2026.1746437

577 views

Review

Accepted on 05 Feb 2026

Exploring Ethical, Sustainable and Effective Foetal Bovine Serum Alternatives for In Vitro Mammalian Cell Culture

Huiyuan Meng
Philip J.R. Day

Frontiers in Toxicology

202 views

Brief Research Report

Published on 05 Feb 2026

A case report of arsenic-induced peripheral neuropathy misdiagnosed as Guillain-Barré syndrome

Shanshan Fu
Guanao Wu
Yibo Zhan
Hui Xia
Chang Zhou
Jingjing Zeng
Ye Tang
Boyan Pan
Zequan Zheng
Min Zhao

Frontiers in Toxicology

doi 10.3389/ftox.2026.1722489

459 views

Mini Review

Published on 05 Feb 2026

Microplastic toxicity: mechanisms, assessment methods, and future research directions

Yifan Zhang
Jiale Ren
Binying Zheng
Jiefang Sun
Jing Zhang
Yumin Niu
Bing Shao
Yushen Jin

Frontiers in Toxicology

doi 10.3389/ftox.2026.1766103

612 views

Perspective

Published on 04 Feb 2026

Foreign body reaction: towards a macrophage-centered adverse outcome pathway for fibrotic encapsulation

Tom Meseberg
Susanne Kurz
Juliane Spohn

Frontiers in Toxicology

doi 10.3389/ftox.2026.1735871

807 views

Original Research

Published on 04 Feb 2026

Clinical features of toxic encephalopathy induced by 1,2-dichloroethane

Yuquan Chen
Yuqiang Lin
Yifan Ye
Meiwen Xie
Jiaqi Chen
Zhiqian Yang
Zhi Wang

Frontiers in Toxicology

doi 10.3389/ftox.2026.1683456

343 views

Original Research

Published on 04 Feb 2026

Multi-task deep learning models for mechanism-based prediction of developmental and reproductive toxicity (DART) using ToxCast bioassays

Siyeol Ahn
Hojun Jung
Jinwon Hwang
Donghyeon Kim
Hyunjun Kim
Wooseok Kim
Yunjung Lee
Changwon Lim
Jinhee Choi

Frontiers in Toxicology

doi 10.3389/ftox.2026.1751644

1,098 views

Review

Published on 03 Feb 2026

New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Jacob Ardenkjær-Skinnerup
Yoni Baert
Lola Bajard
Jonathan Blum
François Brion
Lucia Coppola
Jean-Baptiste Fini
Ellen Fritsche
Henrik Holbech
Selma Hurem

Frontiers in Toxicology

doi 10.3389/ftox.2026.1736963

1,188 views

Original Research

Accepted on 30 Jan 2026

Perspectives on Variability of In Vivo Toxicology Studies: Considerations for Next-generation Toxicology

Agnes L Karmaus
Anna L Kreutz
Oluwakemi Oyetade
Katie Paul Friedman
Martin Paparella
Emily N Reinke
David Allen
Helena Therese Hogberg
Nicole C Kleinstreuer

Frontiers in Toxicology

257 views

Perspective

Published on 29 Jan 2026

Addressing animal methods bias through government-led initiatives

Jessica S. Kopew
Merel Ritskes-Hoitinga
Mikalah Singer
Emily R. Trunnell
Gabby Vidaurre
Catharine E. Krebs

Frontiers in Toxicology

doi 10.3389/ftox.2026.1761759

1,104 views

Original Research

Accepted on 27 Jan 2026

A Comparison of Honeybee and Scorpion Venoms as Anticancer Agents Against three different cancer cell lines: Lung, Colon, and Breast Cancer

Fatma Galal
Fahad M Alshammari
Abdulrahman S. Aldaghmi
Elsayed E. Hafez
Ghada El-sayed
Riyadh H Aeban
Saad A Alharb

Frontiers in Toxicology

246 views

Original Research

Accepted on 27 Jan 2026

Appearance-Based Computer Vision Pipeline for Multi-Animal Monitoring of Canine Activity, Behavior and Clinical Observations

Eline Eberhardt
Jef Plochaet
Tanguy Ophoff
Floris De Feyter
Sarah De Landtsheer
Greet B.A. Teuns
Maarten Vergauwen
Bianca Feyen
Toon Goedemé
Ivan Kopljar

Frontiers in Toxicology

248 views

29 Publications

volumes

Effect of the cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on in vivo platelet activation, oxidative stress, and procoagulant responses induced by waterpipe smoke exposure in mice

Deciphering the toxicological mechanism of airway allergic diseases caused by Dioctyl terephthalate: a composite study

From Prediction to Adaptation: Rethinking the Epistemic Role of Inhalation Toxicology

In Vitro BBB Triculture Assay and Preliminary Computational Model Development to Predict Brain Exposure

Micro/Nanoplastics Pollution: Emerging Challenges for Aquatic Animals and Food Crops

"Algal-dromes": A Novel Conceptual Approach to Illness in Humans Exposed to Harmful Algal Bloom Toxins

Invisible Victims: Rising Pediatric Cocaine Exposures in France (2020–2024) – Insights from the National Poison Center Database

Use of gastroscopy in the management of pediatric toxic ingestions: insights from a decade of experience – a retrospective study

Effects of predicted Khamisiyah exposure on default mode network resting state functional connectivity in Gulf War Veterans

Microplastics amplify the pro-inflammatory response to fungal mycelial fragments and spores in neutrophil-like cells

Ecotoxicological Thresholds of Glyphosate: Linking Sub-Lethal Exposure to Liver Tissue Damage and Behavioural Disturbances in African Catfish

Protective Effects of Lagerstroemia speciosa Against Paracetamol-Induced Renal and Testicular Toxicity in Rats via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Mechanisms

From prioritization to implementation: updating the PARC WP5 project portfolio through the second prioritization round

Exploring Ethical, Sustainable and Effective Foetal Bovine Serum Alternatives for In Vitro Mammalian Cell Culture

A case report of arsenic-induced peripheral neuropathy misdiagnosed as Guillain-Barré syndrome

Microplastic toxicity: mechanisms, assessment methods, and future research directions

Foreign body reaction: towards a macrophage-centered adverse outcome pathway for fibrotic encapsulation

Clinical features of toxic encephalopathy induced by 1,2-dichloroethane

Multi-task deep learning models for mechanism-based prediction of developmental and reproductive toxicity (DART) using ToxCast bioassays

New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Perspectives on Variability of In Vivo Toxicology Studies: Considerations for Next-generation Toxicology

Addressing animal methods bias through government-led initiatives

A Comparison of Honeybee and Scorpion Venoms as Anticancer Agents Against three different cancer cell lines: Lung, Colon, and Breast Cancer

Appearance-Based Computer Vision Pipeline for Multi-Animal Monitoring of Canine Activity, Behavior and Clinical Observations