Frontiers in Tuberculosis

Original Research

Published on 16 Feb 2026

Evaluation of host-immune biomarker signatures as multiplex qPCR diagnostic assays: a pilot study toward meeting WHO target product profiles for TB diagnosis in India

in Diagnosis of Tuberculosis

Harriet N. Garlant
Kalaiarasan Ellappan
Noyal Mariya Joseph
Carrie Turner
Vishnukanth Govindaraj
Saka Vinod Kumar
Sanjeev Kumar
Seshadri Vasan
Karen E. Kempsell

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1678039

476 views

Study Protocol

Published on 13 Feb 2026

An integrated psycho-social intervention to improve self-efficacy toward TB treatment uptake and infection prevention among patients and family caregivers: a multicentric implementation research study protocol

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Karikalan Nagaraj
Bella Devaleenal Daniel
Chandra Suresh
Dhanalakshmi Angamuthu
Shobana Palanisamy
Muniyandi Malaisamy

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1713844

238 views

Original Research

Published on 12 Feb 2026

Acceptability and feasibility of oral swabs for tuberculosis diagnosis in young children: a qualitative study from Uganda and Peru

in Diagnosis of Tuberculosis

Francesca W. Basile
Rodrigo Calderón-Flores
Franziska Held
Luisa Pollmeier
Emmanuel Nasinghe
Godfrey Bagenda
Lazaaro Mujumbusi
Rose Namaganda
Angel Kanyange
Prossy Mbekeeka

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1726647

410 views

Original Research

Accepted on 05 Feb 2026

Evaluation of the performance of promising host transcriptional biosignatures in predicting TB progression during a 1-year prospective cohort study in Indian household contacts

in Diagnosis of Tuberculosis

Synne Jenum
Steffen Hadasch
Dhanasekaran Sivakumaran
Christina Skår Saghaug
Jonas Høgberg
Kasama Chusang Larsen
Sumithra Selvam
Helene Larsen
Christian Ritz
Harleen Grewal

Frontiers in Tuberculosis

209 views

Original Research

Published on 27 Jan 2026

The “yeast-drop” treatment protocol in the Drosophila model for rapid and cost-effective TB drug testing

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Maria Vidal
Esther Fuentes
Nerea Escobar
Marta Arch
Pere-Joan Cardona

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1746664

442 views

Original Research

Published on 13 Jan 2026

Evaluation of a short, all oral treatment regimen including bedaquiline, delamanid, linezolid, clofazimine, and pyrazinamide named “Regimen C” for pre-XDR tuberculosis in Niger

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Soumana Boubacar Soumana
Abdourahamane Yacouba
Cheikh Aboubacar Abdoul Lawi
Ibrahim Oumar
Bassirou Souleymane
Alphazazi Soumana
Tapha Ounoussa
Mahamadou Doutchi
Mamane Daou
Souleymane Brah

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1718997

448 views

Review

Published on 12 Jan 2026

Bidirectional pathogenesis between non-tuberculous mycobacteria and bronchiectasis: clinical insights, diagnostic challenges and future directions—Perspectives from South Asia

in Non-Tuberculous Mycobacteria

Amresh Kumar Singh
Sneha Singh
Nandini Singh
Priyanka Gaur
Ashwini Kumar Mishra
Raj Kishore Singh
Sushil Kumar

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1735568

677 views

Original Research

Published on 09 Jan 2026

A synthesis of youth activation initiatives and their impact on tuberculosis knowledge, knowledge-seeking, and healthcare-seeking behavior in vulnerable populations

in Epidemiology of Tuberculosis

Ana-Maria Ionescu
Joelle Mak
Qu Yan
Nishant Kumar
Raghuram Rao
Sanjay Mattoo
Deepak Balasubramanian
Rachana Acharya
Subhi Quraishi
Niraj Sharma

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1668711

684 views

Original Research

Published on 17 Dec 2025

Proteomic insights into mycobacterial responses to elevated riboflavin reveal a role for flavin-sequestering proteins in flavin homeostasis

in Pathogen and Host Biology of Tuberculosis

Nurudeen Oketade
Karen M. Dobos

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1719707

924 views

Review

Published on 12 Dec 2025

Mycobacteria as evolutionary drivers of host innate immunity: insights from comparing experimental host models

in Pathogen and Host Biology of Tuberculosis

Mariona Cortacans
Pere-Joan Cardona

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1735950

875 views

Perspective

Published on 28 Nov 2025

Implementing TB-Stigma reduction interventions in High Burden Countries: a perspective on a conceptual framework

in Epidemiology of Tuberculosis

Bushra Bibi
Mark Goodall
Injety Ranjit
Stephanie Jones
Colette Miller

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1721361

898 views

Original Research

Published on 06 Nov 2025

Low treatment completion rates reveal gaps in the LTBI care cascade among university students

in Epidemiology of Tuberculosis

Anu K. Murthy
Richard A. Goodman
Miranda A. Moore

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1710215

1,107 views

Original Research

Published on 01 Oct 2025

Predicting treatment adherence in patients with drug-resistant tuberculosis: insights from socioeconomic, demographic, and clinical factors of patients in the rural Eastern Cape

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Lindiwe Modest Faye
Mojisola Clara Hosu
Ntandazo Dlatu
Joshua Iruedo
Teke Apalata

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1659333

1,499 views

Original Research

Published on 25 Sep 2025

Country-level heterogeneity in MDR-TB drug susceptibility supports country-specific policy development

in Epidemiology of Tuberculosis

Naomi M. Fuller
Nicholas G. Davies
Timothy D. McHugh
Gwenan M. Knight

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1667354

1,209 views

Original Research

Published on 02 Sep 2025

Targeted transcriptomic analyses of tuberculosis treatment response and outcomes in The Gambia

in Diagnosis of Tuberculosis

Ismaila L. Manneh
Fatoumatta Darboe
Haddijatou Jobe
Binta Sarr Kuyateh
Ousainou Cham
Olumuyiwa Owolabi
Brezesky Kotanmi
Andrea Rachow
Salome Charalambous
Kathrin Held

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1540194

1,438 views

Review

Published on 12 Aug 2025

The value of LAM and LprG in extracellular vesicles in the diagnostic and therapeutic field of renal tuberculosis

in Diagnosis of Tuberculosis

Xuefeng Peng
Yue Li
Suiyang Jin
Qiang Wang

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1608780

1,457 views

Original Research

Published on 01 Aug 2025

Assessment of knowledge, attitudes, and practices regarding TB prevention and treatment among college students in Wuhan, central China

in Epidemiology of Tuberculosis

Gang Wu
Chao Quan
Aiping Yu
Li Li
Jun Chen
Yun Yang
Guiyang Wang
Zhouqin Lu
Xiaojun Wang
Qionghong Duan

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1587839

2,511 views
1 citation

Original Research

Published on 18 Jul 2025

Risk factors associated with multidrug-resistant pulmonary tuberculosis in patients over 15 years old: a retrospective case-control study

in Epidemiology of Tuberculosis

Odete Bambi Receado
Paulo Ney Solary
Emanuel Catumbela
Carlos Alberto Pinto de Sousa

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1608364

1,383 views

Original Research

Published on 17 Jul 2025

Optimizing use of data and evidence-related tools to complement routine surveillance systems for tuberculosis program planning

in Epidemiology of Tuberculosis

Rachel M. Fiorillo
Eveline Klinkenberg
Christina Braccio
Daniel Chin
Stavia Turyahabwe
Moses Arinaitwe
Razia Fatima
Taye Letta
Binh Hoa Nguyen
Aiban Ronoh

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1622167

2,318 views

Original Research

Published on 09 Jul 2025

Prevalence and risk factors of high blood pressure among persons assessed for TB at three health facilities in Lusaka, Zambia

in Epidemiology of Tuberculosis

Seke G. Y. Muzazu
Daniel Siameka
Nsala Sanjase
Brian Shuma
Mary Kagujje
Monde Muyoyeta

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1548843

1,553 views
1 citation

Editorial

Published on 01 Jul 2025

Editorial: Rising stars in tuberculosis

in Pathogen and Host Biology of Tuberculosis

Harald G. Wiker
Elsa Anes
Philippe Clevenbergh
Seyed Ehtesham Hasnain
Sven Hoffner
Alissa C. Rothchild
Vishwanath Venketaraman

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1635563

1,194 views

Editorial

Published on 26 Jun 2025

Editorial: Discerning active TB from latent infection

in Diagnosis of Tuberculosis

Pere-Joan Cardona
Synne Jenum
Novel N. Chegou

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1623373

1,104 views
1 citation

Original Research

Published on 20 Jun 2025

Trends and impact of government prevention policies on pulmonary tuberculosis notification and mortality in Ningbo, China (2004–2021)

in Epidemiology of Tuberculosis

Tianfeng He
Lin Lin
Xujun Qian
Weitao Yao
Guoxing Li
Jing Huang

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1615486

1,182 views

Original Research

Published on 23 May 2025

Patterns of Mycobacterium tuberculosis genotypes and resistance mutations in patients with pulmonary multidrug-resistant tuberculosis in Sverdlovsk Oblast, Russia

in Pathogen and Host Biology of Tuberculosis

Tatiana Umpeleva
Elena Mazurina
Leonid Lavrenchuk
Sven G. Hinderaker
Einar Heldal
Andrei Mariandyshev
Diana Vakhrusheva
Irina Vasilieva

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1406536

1,574 views
2 citations

57 articles

articles

Evaluation of host-immune biomarker signatures as multiplex qPCR diagnostic assays: a pilot study toward meeting WHO target product profiles for TB diagnosis in India

An integrated psycho-social intervention to improve self-efficacy toward TB treatment uptake and infection prevention among patients and family caregivers: a multicentric implementation research study protocol

Acceptability and feasibility of oral swabs for tuberculosis diagnosis in young children: a qualitative study from Uganda and Peru

Evaluation of the performance of promising host transcriptional biosignatures in predicting TB progression during a 1-year prospective cohort study in Indian household contacts

The “yeast-drop” treatment protocol in the Drosophila model for rapid and cost-effective TB drug testing

Evaluation of a short, all oral treatment regimen including bedaquiline, delamanid, linezolid, clofazimine, and pyrazinamide named “Regimen C” for pre-XDR tuberculosis in Niger

Bidirectional pathogenesis between non-tuberculous mycobacteria and bronchiectasis: clinical insights, diagnostic challenges and future directions—Perspectives from South Asia

A synthesis of youth activation initiatives and their impact on tuberculosis knowledge, knowledge-seeking, and healthcare-seeking behavior in vulnerable populations

Proteomic insights into mycobacterial responses to elevated riboflavin reveal a role for flavin-sequestering proteins in flavin homeostasis

Mycobacteria as evolutionary drivers of host innate immunity: insights from comparing experimental host models

Implementing TB-Stigma reduction interventions in High Burden Countries: a perspective on a conceptual framework

Low treatment completion rates reveal gaps in the LTBI care cascade among university students

Predicting treatment adherence in patients with drug-resistant tuberculosis: insights from socioeconomic, demographic, and clinical factors of patients in the rural Eastern Cape

Country-level heterogeneity in MDR-TB drug susceptibility supports country-specific policy development

Targeted transcriptomic analyses of tuberculosis treatment response and outcomes in The Gambia

The value of LAM and LprG in extracellular vesicles in the diagnostic and therapeutic field of renal tuberculosis

Assessment of knowledge, attitudes, and practices regarding TB prevention and treatment among college students in Wuhan, central China

Risk factors associated with multidrug-resistant pulmonary tuberculosis in patients over 15 years old: a retrospective case-control study

Optimizing use of data and evidence-related tools to complement routine surveillance systems for tuberculosis program planning

Prevalence and risk factors of high blood pressure among persons assessed for TB at three health facilities in Lusaka, Zambia

Editorial: Rising stars in tuberculosis

Editorial: Discerning active TB from latent infection

Trends and impact of government prevention policies on pulmonary tuberculosis notification and mortality in Ningbo, China (2004–2021)

Patterns of Mycobacterium tuberculosis genotypes and resistance mutations in patients with pulmonary multidrug-resistant tuberculosis in Sverdlovsk Oblast, Russia